Evidence for coseismic events of recurrent prehistoric deformation along the Alhama de Murcia fault, southeastern Spain

The Alhama de Murcia fault is a 85 km long oblique-slip fault, and is related to historical and instrumental seismic activity. A paleoseismic analysis of the Lorca-Totana sector of the fault containing MSK I=VIII historical earthquakes was made in order to identify and quantify its seismic potential. We present 1) the results of the neotectonic, structural and geomorphological analyses and, 2) the results of trenching. In the study area, the Alhama de Murcia fault forms a depressed corridor between two strands, the northwestern fault with morphological and structural features of a reverse component of slip, bounding the La Tercia range to the South, and the southeastern fault strand with evidence of sinistral oblique strike-slip movement. The offset along this latter fault trapped the sediments in transit from the La Tercia range towards the Guadalentín depression. The most recent of these sediments are arranged in three generations of alluvial fans and terraces. The first two trenches were dug in the most recent sediments across the southeastern fault strand. The results indicate a coseismic reverse fault deformation that involved the sedimentary sequence up to the intermediate alluvial fan and the Holocene terrace deposits. The sedimentary evolution observed in the trenches suggests an event of temporary damming of the Colmenar creek drainage to the South due to uplifting of the hanging wall during coseismic activation of the fault. Trench, structural and sedimentological features provide evidence of at least three coseismic events, which occurred after 125,000 yr. The minimum vertical slip rate along the fault is 0.06 mm/yr and the average recurrence period should not exceed 40,000 yr in accordance with the results obtained by fan topographic profiling. Further absolute dating is ongoing to constrain these estimates.Se presentan los primeros resultados del estudio paleosísmico del sector Lorca-Totana (con terremotos históricos de I=VIII) de la falla de Alhama de Murcia, de deslizamiento direccional oblícuo sinestroso, para caracterizar su potencial sísmico. Esto incluye: 1) resultados del estudio neotectónico, estructural y geomorfológico y 2) primeros resultados obtenidos en trincheras. El área estudiada muestra dos zonas de falla, la noroeste, que limita la sierra de la Tercia, con morfología y estructuras típicas de movimiento inverso, y la sureste con evidencias de deslizamiento direccional sinestroso, separadas por un corredor deprimido. La actividad de estas fallas ha atrapado en el corredor gran cantidad de sedimentos en su transporte hacia la depresión del Guadalentín, los más recientes de los cuales se organizan en tres generaciones de abanicos aluviales y terrazas. Las dos trincheras se ex c avaron en los sedimentos de la generación intermedia de abanicos aluviales y en la de terrazas más recientes deformados por la falla sureste. Los primeros resultados indican deformación cosísmica con deslizamiento inverso. Se interpreta también un bloqueo temporal del drenaje hacia el sur de la rambla de El Colmenar debido al levantamiento del bloque superior de la falla en un proceso cosísmico. Se describen evidencias de hasta tres paleoterremotos que, en un primer análisis sin datos de edad absoluta, habrían tenido lugar posteriormente a 125.000 años. La velocidad de deslizamiento no sería inferior a 0,06 mm/a y el período de recurrencia no sería mayor a 40.000 años. Estos primeros datos se podrán ajustar mediante dataciones absolutas que están en curso

Effects of repeated paleoearthquakes on the Alhama de Murcia Fault (Betic Cordillera, Spain) on the Quaternary evolution of an alluvial fan system

In this work we present a study of an alluvial fan system, which is affected by the Quaternary activity of the leftlateral, reverse Alhama de Murcia Fault (Betic Cordillera). Paleoseismic studies in this area yield data that can be compared and correlated with the morphologic and tectono-sedimentary evolution of the alluvial fan. The spatial arrangement of the sedimentary alluvial fan units near the fault zone, shown in trenches, is controlled by the recurrent reverse, left-lateral coseismic events. We analysed the morphology of the drainage network using a 1:5000 scale orthoimage to identify and measure horizontal deflections along the fault. The channel pattern analysis allowed us to estimate the average horizontal slip rate of the SAMF for the last 130 ka. This value is 0.21 mm/a, which is slightly higher than the range of values obtained by trenching analysis for the last 30 ka, (0.06 to 0.15 mm/yr). The interpretation of the stratigraphic sequence exposed along the trench walls constrained the occurrence of at least two surface faulting earthquakes during the last 30000 years. The most recent event happened after the El Saltador Creek dissected the alluvial fan. The penultimate event occurred while the alluvial fan was still active

LIUM-CVC submissions for WMT17 multimodal translation task

This paper describes the monomodal and multimodal Neural Machine Translation systems developed by LIUM and CVC for WMT17 Shared Task on Multimodal Translation. We mainly explored two multimodal architectures where either global visual features or convolutional feature maps are integrated in order to benefit from visual context. Our final systems ranked first for both En-De and En-Fr language pairs according to the automatic evaluation metrics METEOR and BLEU

The Gaia spectrophotometric standard stars survey -II. Instrumental effects of six ground-based observing campaigns

The Gaia SpectroPhotometric Standard Stars (SPSS) survey started in 2006, it was awarded almost 450 observing nights, and accumulated almost 100,000 raw data frames, with both photometric and spectroscopic observations. Such large observational effort requires careful, homogeneous, and automated data reduction and quality control procedures. In this paper, we quantitatively evaluate instrumental effects that might have a significant (i.e.,$\geq$1%) impact on the Gaia SPSS flux calibration. The measurements involve six different instruments, monitored over the eight years of observations dedicated to the Gaia flux standards campaigns: DOLORES@TNG in La Palma, EFOSC2@NTT and ROSS@REM in La Silla, [email protected] in Calar Alto, BFOSC@Cassini in Loiano, and [email protected] in San Pedro Martir. We examine and quantitatively evaluate the following effects: CCD linearity and shutter times, calibration frames stability, lamp flexures, second order contamination, light polarization, and fringing. We present methods to correct for the relevant effects, which can be applied to a wide range of observational projects at similar instruments.Comment: 16 pages, 13 figures, accepted for publication in Astron. Nach

The multiplicity fraction in 202 open clusters from Gaia

In this study, we estimate the fraction of binaries with high mass ratios for 202 open clusters in the extended solar neighbourhood (closer than 1.5 kpc from the Sun). This is one of the largest homogeneous catalogues of multiplicity fractions in open clusters to date, including the unresolved and total (close-binary) multiplicity fractions of main-sequence systems with mass ratio larger than $0.6_{-0.15}^{+0.05}$. The unresolved multiplicity fractions are estimated applying a flexible mixture model to the observed Gaia colour-magnitude diagrams of the open clusters. Then we use custom Gaia simulations to account for the resolved systems and derive the total multiplicity fractions. The studied open clusters have ages between 6.6 Myr and 3.0 Gyr and total high-mass-ratio multiplicity fractions between 6% and 80%, with a median of 18%. The multiplicity fractions increase with the mass of the primary star, as expected. The average multiplicity fraction per cluster displays an overall decreasing trend with the open cluster age up to ages about 100 Myr, above which the trend increases. Our simulations show that most of this trend is caused by complex selection effects (introduced by the mass dependence of the multiplicity fraction and the magnitude limit of our sample). Furthermore, the multiplicity fraction is not significantly correlated with the clusters' position in the Galaxy. The spread in multiplicity fraction decreases significantly with the number of cluster members (used as a proxy for cluster mass). We also find that the multiplicity fraction decreases with metallicity, in line with recent studies using field stars.Comment: 17 pages, 13 figures, resubmitted to A&A following referee comment

Kinematic analysis of the Large Magellanic Cloud using Gaia DR3

Context: The high quality of the Gaia mission data is allowing to study the internal kinematics of the Large Magellanic Cloud (LMC) in unprecedented detail, providing insights on the non-axisymmetric structure of its disc. Aims: To define and validate an improved selection strategy to distinguish the LMC stars from the Milky Way foreground. To check the possible biases that assumed parameters or sample contamination from the Milky Way can introduce in the analysis of the internal kinematics of the LMC using Gaia data. Methods: Our selection is based on a supervised Neural Network classifier using as much as of the Gaia DR3 data as possible. We select three samples of candidate LMC stars with different degrees of completeness and purity; we validate them using different test samples and we compare them with the Gaia Collaboration paper sample. We analyse the resulting velocity profiles and maps, and we check how these results change when using also the line-of-sight velocities, available for a subset of stars. Results: The contamination in the samples from Milky Way stars affects basically the results for the outskirts of the LMC, and the absence of line-of-sight velocities does not bias the results for the kinematics in the inner disc. For the first time, we perform a kinematic analysis of the LMC using samples with the full three dimensional velocity information from Gaia DR3. Conclusions: The dynamics in the inner disc is mainly bar dominated; the kinematics on the spiral arm over-density seem to be dominated by an inward motion and a rotation faster than that of the disc in the piece of the arm attached to the bar; contamination of MW stars seem to dominate the outer parts of the disc and mainly affects old evolutionary phases; uncertainties in the assumed disc morphological parameters and line-of-sight velocity of the LMC can in some cases have significant effects. [ABRIDGED

Adipose-Derived Fatty Acid-Binding Proteins Plasma Concentrations Are Increased in Breast Cancer Patients.

BACKGROUND: Adipose tissue is an endocrine organ that could play a role in tumor progression via its secreted adipokines. The role of adipose-derived fatty acid-binding protein (FABP) 4 and FABP5 in breast cancer is presently under study, but their circulating levels in this pathology are poorly known. We analyzed the blood concentrations of FABP4 and FABP5 in breast cancer patients to determine whether there is an association between them and breast cancer. MATERIALS AND METHODS: We studied 294 women in the oncology department with a family history of breast cancer; 198 of the women had breast cancer, and 96 were healthy controls. The levels of FABP4, FABP5, lipid profile, standard biochemical parameter, and high-sensitivity C-reactive protein (hsCRP) were determined. We analyzed the association of FABP4 and FABP5 with breast cancer, while adjusting for demographic, anthropometric, and biochemical parameters. RESULTS: Breast cancer patients had a 24.8% (p < .0001) and 11.4% (p < .05) higher blood concentration of FABP4 and FABP5, respectively. Fatty acid-binding protein 4 was positively associated with age, body mass index (BMI), FABP5, very-low-density lipoprotein cholesterol (VLDLc), non-high-density lipoprote in cholesterol (non-HDLc), Apolipoprotein B 100 (ApoB100), triglycerides, glycerol, glucose, and hsCRP (p < .05), and was negatively associated with HDLc (p < .005) in breast cancer patients. Fatty acid-binding protein 5 was positively associated with BMI, FABP4, VLDLc, triglycerides, glycerol, and hsCRP (p < .05), and was negatively associated with HDLc and Apolipoprotein AI (ApoAI) (p < .05) in breast cancer patients. Using a logistic regression analysis and adjusting for age, BMI, hsCRP, non-HDLc, and triglycerides, FABP4 was independently associated with breast cancer (odds ratio [OR]: 1.091 [95% CI: 1.037-1.149]). Moreover, total cholesterol, VLDLc, non-HDLc, ApoB100, triglycerides, and hsCRP were significantly increased in breast cancer patients (p < .005). In contrast, the non-esterified fatty acids concentrations were significantly decreased in breast cancer patients (p < .05). CONCLUSION: Circulating FABP4 and FABP5 levels were increased in breast cancer patients compared with controls. The positive association of FABP4 with breast cancer was maintained after adjusting for important covariates, while the association with FABP5 was lost. Our data reinforce the role of adipose tissue and their adipokines in breast cancer. Despite these data, further studies must be performed to better explain the prognosis or diagnostic value of these blood parameters and their possible role in breast cancer. IMPLICATIONS FOR PRACTICE: We focus on the effect of adipose tissue on cancer, which is increasingly recognized. The association between adipocyte-derived adipokines and breast cancer opens new diagnosis and therapy perspectives. In this study, we provide original data concerning FABP4 and FABP5 plasma concentrations in breast cancer patients. Compared to control group, breast cancer patients show higher FABP4 and FABP5 blood levels. Our data suggest that, particularly, circulating FABP4 levels could be considered a new independent breast cancer biomarker. Our work translates basic science data to clinic linking the relationship between adipose tissue and lipid metabolism to breast cancer

Bright low mass eclipsing binary candidates observed by STEREO

Observations from the Heliospheric Imagers (HI-1) on both the STEREO spacecraft have been analysed to search for bright low mass eclipsing binaries (EBs) and potential brown dwarf transits and to determine the radii of the companions. A total of 9 EB candidates have been found, ranging in brightness from V=6.59 mag to V=11.3 mag, where the radius of the companion appears to be less than 0.4 Rsol, with a diverse range of host temperatures, from 4074 K to 6925 K. Both components of one candidate, BD-07 3648, appear to be less than 0.4 Rsol and this represents a particularly interesting system for further study. The shapes of the eclipses in some cases are not clear enough to be certain they are total and the corresponding radii found should therefore be considered as lower limits. The EBs reported in this paper have either been newly found by the present analysis, or previously reported to be eclipsing by our earlier STEREO/HI-1 results. One of the new objects has subsequently been confirmed using archival SuperWASP data. This study was made possible by using an improved matched filter extraction algorithm, which is described in this paper.Comment: 11 pages, 6 figures, 2 tables, accepted for publication in MNRA

Enhanced sensitivity of MRM-based protein quantitation using a triple quadrupole LC/MS system with dual ion funnel

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