Uniform attractors for a non-autonomous semilinear heat equation with memory

n this paper we investigate the asymptotic behavior, as time tends to infinity, of the solutions of a non-autonomous integro-partial differential equation describing the heat how in a rigid heat conductor with memory. Existence and uniqueness of solutions is provided. Moreover, under proper assumptions on the heat flux memory kernel and on the magnitude of nonlinearity, the existence of uniform absorbing sets and of a global uniform attractor is achieved. In the case of quasiperiodic dependence of time of the external heat supply the above attractor is shown to have finite Hausdorff dimension

Response of microchannel plates in ionization mode to single particles and electromagnetic showers

Hundreds of concurrent collisions per bunch crossing are expected at future hadron colliders. Precision timing calorimetry has been advocated as a way to mitigate the pileup effects and, thanks to their excellent time resolution, microchannel plates (MCPs) are good candidate detectors for this goal. We report on the response of MCPs, used as secondary emission detectors, to single relativistic particles and to electromagnetic showers. Several prototypes, with different geometries and characteristics, were exposed to particle beams at the INFN-LNF Beam Test Facility and at CERN. Their time resolution and efficiency are measured for single particles and as a function of the multiplicity of particles. Efficiencies between 50% and 90% to single relativistic particles are reached, and up to 100% in presence of a large number of particles. Time resolutions between 20ps and 30ps are obtained.Comment: 20 pages, 9 figures. Paper submitted to NIM

Scoring and ranking probabilistic seismic hazard models: an application based on macroseismic intensity data

A probabilistic seismic hazard model consists of a set of weighted models/branches that describes the center, the body and the range of seismic hazard. Owing to the intrinsic nature of this kind of analysis, the weight of each model/branch represents its scientific credibility. However, practical uses of this model may sometimes require the selection of one or a few hazard curves that are sampled from the whole model, which often consists of thousands of branches. Here we put forward an innovative procedure that facilitates the scoring, ranking and selection of the hazard curves to account for the requirements of a specific application. The approach consists of a careful quality check of the data used for scoring and the adoption of a proper scoring rule. To show the applicability of this approach, we present an example that consists of scoring and ranking a set of multiple models/branches constituting a recent seismic hazard model of Italy. To score these branches, hazard estimates produced by each of them are compared with time series of macroseismic observations available in the Italian macroseismic database for a carefully selected set of localities deemed sufficiently representative, homogeneously distributed in space and complete with respect to time and intensity levels. The proper scoring parameter used for such a comparison is the logarithmic score, which can always be applied independently of the distribution of the data.</p

Reaching activity in parietal area V6A of macaque: eye influence on arm activity or retinocentric coding of reaching movements?

Parietal area V6A contains neurons modulated by the direction of gaze as well as neurons able to code the direction of arm movement. The present study was aimed to disentangle the gaze effect from the effect of reaching activity upon single V6A neurons. To this purpose, we used a visuomotor task in which the direction of arm movement remained constant while the animal changed the direction of gaze. Gaze direction modulated reach-related activity in about two-thirds of tested neurons. In several cases, modulations were not due to the eye-position signal per se, the apparent eye-position modulation being just an epiphenomenon. The real modulating factor was the location of reaching target with respect to the point gazed by the animal, that is, the retinotopic coordinates towards which the action of reaching occurred. Comparison of neural discharge of the same cell during execution of foveated and non-foveated reaching movements, performed towards the same or different spatial locations, confirmed that in a part of V6A neurons reaching activity is coded retinocentrically. In other neurons, reaching activity is coded spatially, depending on the direction of reaching movement regardless of where the animal was looking at. The majority of V6A reaching neurons use a system that encompasses both of these reference frames. These results are in line with the view of a progressive visuomotor transformation in the dorsal visual stream, that changes the frame of reference from the retinocentric one, typically used by the visual system, to the arm-centred one, typically used by the motor system

Clinical impact of an inter-hospital transfer strategy in patients with ST-elevation myocardial infarction undergoing primary angioplasty: the Emilia-Romagna ST-segment elevation acute myocardial infarction network

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Executive functions in children with specific learning disorders: Shedding light on a complex profile through teleassessment

Executive Functions (EFs) are high-order cognitive processes relevant to learning and adaptation and frequently impaired in children with specific learning disorders (SLDs). This study aimed to investigate EFs in children with SLD and explore the role of specific EF-related subprocesses, such as stimuli processing and processing speed. Fifty-seven SLD and 114 typically developing (TD) children, matched for gender and age, completed four tasks measuring response inhibition, interference control, shifting, and updating on a web-based teleassessment platform. The results show that SLD children performed lower in all EF tasks than TD children, regardless of stimulus type and condition. Mediation analyses suggested that differences between the SLD and TD groups are mediated by EF-related subprocesses, offering an interpretative model of EF deficits in children with SLD

Ocean Modeling on a Mesh With Resolution Following the Local Rossby Radius

We discuss the performance of the Finite Element Ocean Model (FESOM) on locally eddy-resolving global unstructured meshes. In particular, the utility of the mesh design approach whereby mesh horizontal resolution is varied as half the Rossby radius in most of the model domain is explored. Model simulations on such a mesh (FESOM-XR) are compared with FESOM simulations on a smaller-size mesh, where refinement depends only on the pattern of observed variability (FESOM-HR). We also compare FESOM results to a simulation of the ocean model of the Max Planck Institute for Meteorology (MPIOM) on a tripolar regular grid with refinement toward the poles, which uses a number of degrees of freedom similar to FESOM-XR. The mesh design strategy, which relies on the Rossby radius and/or the observed variability pattern, tends to coarsen the resolution in tropical and partly subtropical latitudes compared to the regular MPIOM grid. Excessive variations of mesh resolution are found to affect the performance in other nearby areas, presumably through dissipation that increases if resolution is coarsened. The largest improvement shown by FESOM-XR is a reduction of the surface temperature bias in the so-called North-West corner of the North Atlantic Ocean where horizontal resolution was increased dramatically. However, other biases in FESOM-XR remain largely unchanged compared to FESOM-HR. We conclude that resolving the Rossby radius alone (with two points per Rossby radius) is insufficient, and that careful use of a priori information on eddy dynamics is required to exploit the full potential of ocean models on unstructured meshes

Multi-dimensional scaling techniques unveiled gain1q&loss13q co-occurrence in Multiple Myeloma patients with specific genomic, transcriptional and adverse clinical features

The complexity of Multiple Myeloma (MM) is driven by several genomic aberrations, interacting with disease-related and/or -unrelated factors and conditioning patients’ clinical outcome. Patient’s prognosis is hardly predictable, as commonly employed MM risk models do not precisely partition high- from low-risk patients, preventing the reliable recognition of early relapsing/refractory patients. By a dimensionality reduction approach, here we dissect the genomic landscape of a large cohort of newly diagnosed MM patients, modelling all the possible interactions between any MM chromosomal alterations. We highlight the presence of a distinguished cluster of patients in the low-dimensionality space, with unfavorable clinical behavior, whose biology was driven by the co-occurrence of chromosomes 1q CN gain and 13 CN loss. Presence or absence of these alterations define MM patients overexpressing either CCND2 or CCND1, fostering the implementation of biology-based patients’ classification models to describe the different MM clinical behaviors

Constraints on the χ_(c1) versus χ_(c2) polarizations in proton-proton collisions at √s = 8 TeV

The polarizations of promptly produced χ_(c1) and χ_(c2) mesons are studied using data collected by the CMS experiment at the LHC, in proton-proton collisions at √s=8  TeV. The χ_c states are reconstructed via their radiative decays χ_c → J/ψγ, with the photons being measured through conversions to e⁺e⁻, which allows the two states to be well resolved. The polarizations are measured in the helicity frame, through the analysis of the χ_(c2) to χ_(c1) yield ratio as a function of the polar or azimuthal angle of the positive muon emitted in the J/ψ → μ⁺μ⁻ decay, in three bins of J/ψ transverse momentum. While no differences are seen between the two states in terms of azimuthal decay angle distributions, they are observed to have significantly different polar anisotropies. The measurement favors a scenario where at least one of the two states is strongly polarized along the helicity quantization axis, in agreement with nonrelativistic quantum chromodynamics predictions. This is the first measurement of significantly polarized quarkonia produced at high transverse momentum