470 research outputs found
Transnational labor regulation, reification and commodification: A critical review
Why does scholarship on transnational labor regulation
(TLR) consistently fails to search for improvements in
working conditions, and instead devotes itself to relentless
efforts for identifying administrative processes, semantics,
and amalgamations of stakeholders? This article critiques
TLR from a pro-worker perspective, through the philosophical
work of Georg Lukács, and the concepts of reification
and commodification. A set of theoretically grounded criteria
is developed and these are applied against selected
contemporary cases of TLR. In the totality that is capitalism,
reification of social relations of production conceals
completely the experiences of workers. In TLR, managerialist
and process-oriented scholarship is dominant, verifiable
outcomes and positive improvements in conditions of
employment are not sought, and worse, meaningless
procedures are celebrated as positive achievements
Dialectics and difference: against Harvey's dialectical post-Marxism
David Harvey`s recent book, Justice, nature and the geography of difference (JNGD), engages with a central philosophical debate that continues to dominate human geography: the tension between the radical Marxist project of recent decades and the apparently disempowering relativism and `play of difference' of postmodern thought. In this book, Harvey continues to argue for a revised `post-Marxist' approach in human geography which remains based on Hegelian-Marxian principles of dialectical thought. This article develops a critique of that stance, drawing on the work of Jacques Derrida, Gilles Deleuze and Felix Guattari. I argue that dialectical thinking, as well as Harvey's version of `post-Marxism', has been undermined by the wide-ranging `post-' critique. I suggest that Harvey has failed to appreciate the full force of this critique and the implications it has for `post-Marxist' ontology and epistemology. I argue that `post-Marxism', along with much contemporary human geography, is constrained by an inflexible ontology which excessively prioritizes space in the theory produced, and which implements inflexible concepts. Instead, using the insights of several `post-' writers, I contend there is a need to develop an ontology of `context' leading to the production of `contextual theories'. Such theories utilize flexible concepts in a multilayered understanding of ontology and epistemology. I compare how an approach which produces a `contextual theory' might lead to more politically empowering theory than `post-Marxism' with reference to one of Harvey's case studies in JNGD
VEGF and Angiopoietin-1 Exert Opposing Effects on Cell Junctions by Regulating the Rho GEF Syx
Vascular endothelial growth factor (VEGF) and Ang1 (Angiopoietin-1) have opposing effects on vascular permeability, but the molecular basis of these effects is not fully known. We report in this paper that VEGF and Ang1 regulate endothelial cell (EC) junctions by determining the localization of the RhoA-specific guanine nucleotide exchange factor Syx. Syx was recruited to junctions by members of the Crumbs polarity complex and promoted junction integrity by activating Diaphanous. VEGF caused translocation of Syx from cell junctions, promoting junction disassembly, whereas Ang1 maintained Syx at the junctions, inducing junction stabilization. The VEGF-induced translocation of Syx from EC junctions was caused by PKD1 (protein kinase D1)-mediated phosphorylation of Syx at Ser806, which reduced Syx association to its junctional anchors. In support of the pivotal role of Syx in regulating EC junctions, syx−/− mice had defective junctions, resulting in vascular leakiness, edema, and impaired heart function
Sequential innovation, naked exclusion, and upfront lump-sum payments
We present a potentially benign naked exclusion mechanism that can be applied to sequential innovation; a non-patentable original innovation by the incumbent supplier fosters derivative innovation by rivals. In the absence of an appropriate legal framework, the original innovator’s equilibrium exclusivity contracts block subsequent efficient entry even if there is (leader-follower) competition in the contracting phase. However, the legal framework may maximize social welfare by imposing a ban on upfront lumps-sum payments in exclusivity contracts (by all suppliers) combined with an outright ban on exclusivity contracts by the derivative innovator. The former ban precludes the exclusion of socially beneficial derivative innovation by causing the incumbent supplier to resort to accommodation, rather than to pure exclusion, strategies. The latter ban complements the former by preventing inefficient or excessive derivative innovation
Schools and skills of critical thinking for urban design
© 2017, © 2017 Informa UK Limited, trading as Taylor & Francis Group. This paper explores possible ways in which urban design can engage with critical thinking and critical theory. After a brief explanation of the terms, with particular attention to the Frankfurt School of thought, it provides various answers to the question as to whether urban design is critical or not. One categorization applied to planning critical theory is then used to explain the potential for employing critical theories in urban design. Critical thinking skills are then argued to be helpful for enriching the literature of urban design in order to achieve better practice. The conclusion is that urban design can benefit from critical creativity, which is an embodiment of critical thinking within the limits imposed onto creativity. In this paper, the ways in which urban design can engage with both critical theory and with critical thinking are explored in order to achieve better critical creativity in the field
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Smart sensor technology for joint test assembly flights.
The world relies on sensors to perform a variety of tasks from the mundane to sophisticated. Currently, processors associated with these sensors are sufficient only to handle rudimentary logic tasks. Though multiple sensors are often present in such devices, there is insufficient processing power for situational understanding. Until recently, no processors that met the electrical power constraints for embedded systems were powerful enough to perform sophisticated computations. Sandia performs many expensive tests using sensor arrays. Improving the efficacy, reliability and information content resulting from these sensor arrays is of critical importance. With the advent of powerful commodity processors for embedded use, a new opportunity to do just that has presented itself. This report describes work completed under Laboratory-Directed Research and Development (LDRD) Project 26514, Task 1. The goal of the project was to demonstrate the feasibility of using embedded processors to increase the amount of useable information derived from sensor arrays while improving the believability of the data. The focus was on a system of importance to Sandia: Joint Test Assemblies for ICBM warheads. Topics discussed include: (1) two electromechanical systems to provide data, (2) sensors used to monitor those systems, (3) the processors that provide decision-making capability and data manipulation, (4) the use of artificial intelligence and other decision-making software, and (5) a computer model for the training of artificial intelligence software
Structural factors controlling the spin-spin exchange coupling: EPR spectroscopic studies of highly asymmetric trityl-nitroxide biradicals
Highly asymmetric exchange-coupled biradicals, like the trityl-nitroxides (TN), possess particular magnetic properties opening new possibilities for their application in biophysical, physicochemical and biological studies. In the present work, we investigated the effect of the linker length on the spin-spin coupling interaction in TN biradicals using the newly synthesized biradicals CT02-GT, CT02-AT, CT02-VT and CT02-PPT as well as the previously reported biradicals TNN14 and TN1. Results show that the magnitude of the spin-spin interaction (J) can be easily tuned from ~ 4 G (conformer 1 in CT02-PPT) to over 1200 G (in TNN14) using various linkers separating the two radical moieties and with varying temperature. Computer simulation of EPR spectra was carried out to directly estimate J values of the TN biradicals. In addition to the spin-spin coupling interaction of TN biradicals, their g, hyperfine splitting and zero-field splitting interactions were explored at low temperature (220 K). Our present study clearly shows that the spin-spin interaction variation as a function of linker distance and temperature provides an effective strategy to develop new TN biradicals which can find wide applications in relevant fields
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