18 research outputs found

    Pisces, Characiformes, Characidae, Glandulocaudinae, <i>Mimagoniates barberi</i> Regan, 1907: First Argentinean distribution record.

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    The current note reports the presence of Mimagoniates barberi at northeastern Argentina. This record representsthe southernmost limit for this species and the first country record of the genus

    The theoretical capacity of the Parity Source Coder

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    The Parity Source Coder is a protocol for data compression which is based on a set of parity checks organized in a sparse random network. We consider here the case of memoryless unbiased binary sources. We show that the theoretical capacity saturate the Shannon limit at large K. We also find that the first corrections to the leading behavior are exponentially small, so that the behavior at finite K is very close to the optimal one.Comment: Added references, minor change

    Linear Complexity Lossy Compressor for Binary Redundant Memoryless Sources

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    A lossy compression algorithm for binary redundant memoryless sources is presented. The proposed scheme is based on sparse graph codes. By introducing a nonlinear function, redundant memoryless sequences can be compressed. We propose a linear complexity compressor based on the extended belief propagation, into which an inertia term is heuristically introduced, and show that it has near-optimal performance for moderate block lengths.Comment: 4 pages, 1 figur

    Dravet syndrome as epileptic encephalopathy: evidence from long-term course and neuropathology

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    Dravet syndrome is an epilepsy syndrome of infantile onset, frequently caused by SCN1A mutations or deletions. Its prevalence, long-term evolution in adults and neuropathology are not well known. We identified a series of 22 adult patients, including three adult post-mortem cases with Dravet syndrome. For all patients, we reviewed the clinical history, seizure types and frequency, antiepileptic drugs, cognitive, social and functional outcome and results of investigations. A systematic neuropathology study was performed, with post-mortem material from three adult cases with Dravet syndrome, in comparison with controls and a range of relevant paediatric tissue. Twenty-two adults with Dravet syndrome, 10 female, were included, median age 39 years (range 20–66). SCN1A structural variation was found in 60% of the adult Dravet patients tested, including one post-mortem case with DNA extracted from brain tissue. Novel mutations were described for 11 adult patients; one patient had three SCN1A mutations. Features of Dravet syndrome in adulthood include multiple seizure types despite polytherapy, and age-dependent evolution in seizure semiology and electroencephalographic pattern. Fever sensitivity persisted through adulthood in 11 cases. Neurological decline occurred in adulthood with cognitive and motor deterioration. Dysphagia may develop in or after the fourth decade of life, leading to significant morbidity, or death. The correct diagnosis at an older age made an impact at several levels. Treatment changes improved seizure control even after years of drug resistance in all three cases with sufficient follow-up after drug changes were instituted; better control led to significant improvement in cognitive performance and quality of life in adulthood in two cases. There was no histopathological hallmark feature of Dravet syndrome in this series. Strikingly, there was remarkable preservation of neurons and interneurons in the neocortex and hippocampi of Dravet adult post-mortem cases. Our study provides evidence that Dravet syndrome is at least in part an epileptic encephalopathy

    Expression patterns of glial fibrillary acidic protein (GFAP)-delta in epilepsy-associated lesional pathologies

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    AIMS: Glial fibrillary acidic protein (GFAP)-delta is a novel isoform that differs in its C-terminal sequence from other GFAP isoforms. Previous studies suggest restriction of expression to the subpial layer, subventricular zone and the subgranular zone astrocytes, with an absence in pathological conditions causing reactive gliosis. GFAP-delta is speculated to have roles in regulation of astrocyte size and motility and a subpopulation of GFAP-delta-positive glia may be multipotent stem cells. The aim of this study was to investigate its expression in common causes of lesion-related refractory epilepsy. METHODS: Hippocampal sclerosis (HS), focal cortical dysplasia (FCD) type IIB, cortical tuberous sclerosis (TSC) lesions, gangliogliomas, grey matter heterotopias and hemimegalencephaly from a wide age range of patients using both surgical and post mortem tissue specimens were studied. RESULTS: GFAP-delta expression was observed in CA4 and CA1 astrocytes in HS with less frequent labelling in the granule cell layer, even where granule cell dispersion was present. No significant labelling was noted in the subiculum in HS cases or in any subfields in non-HS epilepsy cases. Balloon cells in FCDIIB and hemimegalencephaly, giant cells in TSC and the astrocytic component of gangliogliomas showed immunoreactivity, colocalizing with conventional GFAP. No neuronal expression for GFAP-delta was seen in any of the pathologies. Quantitative analysis in 10 FCDIIB and five TSC cases revealed greater numbers of GFAP-delta-positive balloon cells than conventional GFAP. There was no GFAP-delta expression within nodular heterotopia. CONCLUSIONS: GFAP-delta expression patterns in HS overall appears to mirror regional reactive gliosis. It is a useful marker for the demonstration of balloon cells in FCD and TSC, which may be relevant to their abnormal size and localization. The lack of GFAP-delta within heterotopia supports their composition from cells destined for deeper cortical layer

    Iris Template Protection

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    Witsenhausen’s counterexample and its links with multimedia security problems

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    Witsenhausen’s counterexample was proposed more than four decades ago in order to show that affine control strategies are not optimal for systems with non-classical information patterns. Finding the optimal solution to Witsenhausen’s problem however remains an open problem. Recently, the stochastic control community has re-discovered Costa’s Dirty Paper result as a potential solution to Witsenhausen’s problem. In this paper the similarities and differences between Witsenhausen’s scenario and multimedia security problems are reviewed, and the historical evolution of the solutions to Witsenhausen’s problem compared with those proposed for watermarking detection
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