2,565 research outputs found
Colonialism and Male Domestic Service Across the Asia Pacific
Examining the role of Asian and indigenous male servants across the Asia Pacific from the late-19th century to the 1930s, this study shows how their ubiquitous presence in these purportedly \u27humble\u27 jobs gave them a degree of cultural influence that has been largely overlooked in the literature on labour mobility in the age of empire. With case studies from British Hong Kong, Singapore, Northern Australia, Fiji and British Columbia, French Indochina, the American Philippines and the Dutch East Indies, the book delves into the intimate and often conflicted relationships between European and American colonists and their servants. It explores the lives of \u27houseboys\u27, cooks and gardeners in the colonial home, considers the bell-boys and waiters in the grand colonial hotels, and follows the stewards and cabin-boys on steamships travelling across the Indian and Pacific Oceans. This broad conception of service allows Colonialism and Male Domestic Service across Asia and the Pacific to illuminate trans-colonial or cross-border influences through the mobility of servants and their employers. This path-breaking study is an important book for students and scholars of colonialism, labour history and the Asia Pacific region
Design principles for the future internet architecture
Design principles play a central role in the architecture of the Internet as driving most engineering decisions at conception level and operational level. This paper is based on the EC Future Internet Architecture (FIArch) Group results and identifies some of the design principles that we expect to govern the future architecture of the Internet. We believe that it may serve as a starting point and comparison for most research and development projects that target the so-called Future Internet Architecture
Low tortoise abundances in pine forest plantations in forest-shrubland transition areas
The Spanish Ministry of Science and European Regional Development Fund funded this work through Projects CGL2012-33536 and CGL2015- 64144; MINECIO/FEDER. Regional Government of the Community of Valencia supported R.R-C. by a postgraduate grant (ACIF/2010/133) and E.G. by a postdoctoral grant (APOSTD/2015/048).In the transition between Mediterranean forest and the arid subtropical shrublands of the southeastern Iberian Peninsula, humans have transformed habitat since ancient times. Understanding the role of the original mosaic landscapes in wildlife species and the effects of the current changes as pine forest plantations, performed even outside the forest ecological boundaries, are important conservation issues. We studied variation in the density of the endangered spur-thighed tortoise (Testudo graeca) in three areas that include the four most common land types within the species’ range (pine forests, natural shrubs, dryland crop fields, and abandoned crop fields). Tortoise densities were estimated using a two-stage modeling approach with line transect distance sampling. Densities in dryland crop fields, abandoned crop fields and natural shrubs were higher (>6 individuals/ha) than in pine forests (1.25 individuals/ha). We also found large variation in density in the pine forests. Recent pine plantations showed higher densities than mature pine forests where shrub and herbaceous cover was taller and thicker. We hypothesize that mature pine forest might constrain tortoise activity by acting as partial barriers to movements. This issue is relevant for management purposes given that large areas in the tortoise’s range have recently been converted to pine plantations.Publisher PDFPeer reviewe
Increasing tuberculosis burden in Latin America: an alarming trend for global control efforts.
Editoria
Differential protein expression of hippocampal cells associated with heavy metals (Pb, As, and MeHg) neurotoxicity::Deepening into the molecular mechanism of neurodegenerative diseases
Chronic exposure to heavy metals such as Pb, As, and MeHg can be associated with an increased risk of developing neurodegenerative diseases. Our in vitro bioassays results showed the potency of heavy metals in the order of Pb <As <MeHg on hippocampal cells. The main objective of this study was combining in vitro label free proteomics and systems biology approach for elucidating patterns of biological response, discovering underlying mechanisms of Pb, As, and MeHg toxicity in hippocampal cells. The omics data was refined by using different filters and normalization and multilevel analysis tools were employed to explore the data visualization. The functional and pathway visualization was performed by using Gene ontology and PathVisio tools. Using these all integrated approaches, we identified significant proteins across treatments within the mitochondrial dysfunction, oxidative stress, ubiquitin proteome dysfunction, and mRNA splicing related to neurodegenerative diseases. The systems biology analysis revealed significant alterations in proteins implicated in Parkinson's disease (PD) and Alzheimer's disease (AD). The current proteomics analysis of three metals support the insight into the proteins involved in neurodegeneration and the altered proteins can be useful for metal-specific biomarkers of exposure and its adverse effects.Significance: The proteomics techniques have been claimed to be more sensitive than the conventional toxicological assays, facilitating the measurement of responses to heavy metals (Pb, As, and MeHg) exposure before obvious harm has occurred demonstrating their predictive value. Also, proteomics allows for the comparison of responses between Pb, As, and MeHg metals, permitting the evaluation of potency differences hippocampal cells of the brain. Hereby, the molecular information provided by pathway and gene functional analysis can be used to develop a more thorough understanding of each metal mechanism at the protein level for different neurological adverse outcomes (e.g. Parkinson's disease, Alzheimer's diseases). Efforts are put into developing proteomics based toxicity testing methods using in vitro models for improving human risk assessment. Some of the key proteins identified can also potentially be used as biomarkers in epidemiologic studies. These heavy metal response patterns shed new light on the mechanisms of mRNA splicing, ubiquitin pathway role in neurodegeneration, and can be useful for the development of molecular biomarkers of heavy metals exposure.</p
Design of the nutritional therapy for overweight and obese Spanish adolescents conducted by registered dieticians: the EVASYON study
Background: Dietary treatment for obese adolescents should aim to ensure adequate growth and development, by reducing excessive fat mass accumulation, avoiding loss of lean body mass, improving well-being and selfesteem and preventing cyclical weight regain. The aim of this article is to describe the dietary intervention design and the methods used to evaluate nutritional knowledge and behavior in the EVASYON study (Development, implementation and evaluation of the efficacy of a therapeutic programme for overweight/obese adolescents). Methods/design: EVASYON is a multi-centre study conducted in 5 Spanish hospital settings (Granada, Madrid, Pamplona, Santander and Zaragoza), where 204 overweight/obese Spanish adolescents were treated in groups of 9 to 11 subjects over 20 visits. The study was implemented in two stages: an intensive, calorie-restricted period for the first 9 weeks, and an extensive body-weight follow-up period for the last 11 months. A moderate energy intake restriction was applied in the intensive period according to the degree of obesity, on the basis of a balanced diet supplying 50-55% of daily energy as carbohydrates; 30-35% as fats and 10-15% as proteins. In the intensive period, adolescents were prescribed both a fixed full-day meal plan for the first three weeks and a full day meal plan with different food-choices for 6 weeks. Later, adolescents received a flexible meal plan based on food exchanges for the follow-up period until the end of the trial. Data on food intake, dietary and meal-related habits and behavior were collected by means of dietary questionnaires. To analyse nutritional knowledge, adolescents were examined regarding nutrient concepts and food items for a healthy diet with the appropriate tools. Participants were given nutritional information with complementary teaching material, which was available on the EVASYON website (www.estudioevasyon.com). Discussion: The dietary intervention of the EVASYON programme with a moderate calorie restriction for a limi - ted period of time could be a good strategy in treating overweight and obese adolescents and that will be tested further. Moreover, combining fixed plan with free-choice menus may help adolescents and their families to make right decisions for every day meals
The Physical Activity and Redesigned Community Spaces (PARCS) Study: Protocol of a Natural Experiment to Investigate The Impact of Citywide Park Redesign and Renovation
Background: The built environment plays a critical role in promoting physical activity and health. The association between parks, as a key attribute of the built environment, and physical activity, however, remains inconclusive. This project leverages a natural experiment opportunity to assess the impact of the Community Parks Initiative (CPI), a citywide park redesign and renovation effort in New York City, on physical activity, park usage, psychosocial and mental health, and community wellbeing.
Methods: The project will use a longitudinal design with matched controls. Thirty intervention park neighborhoods are socio-demographically matched to 20 control park neighborhoods. The study will investigate whether improvements in physical activity, park usage, psychosocial and mental health, and community wellbeing are observed from baseline to 3 years post-renovation among residents in intervention vs. control neighborhoods.
Discussion: This study represents a rare opportunity to provide robust evidence to further our understanding of the complex relationship between parks and health. Findings will inform future investments in health-oriented urban design policies and offer evidence for addressing health disparities through built environment strategies
Comment Re: Non-Compete Clause Rulemaking, Matter No. P201200
Within signed law professors and law students submitted this letter to the Federal Trade Commission, writing in their individual capacities, not as agents of their affiliated institutions, in support of the Federal Trade Commission’s proposed rule to ban most non-compete clauses (the “Proposal”) as an unfair method of competition.
This letter offers comments in response to areas where the FTC has requested public comment. To make our views clear, this letter contains the following sections:
I. Summary of the Proposal;
II. The Commission Should Consider Expanding Its Definition of Non-Compete Clauses to Prevent Employers from Requiring Workers to Quit Before Seeking Alternative Employment;
III. Non-Compete Clauses Are Unfair Methods of Competition;
IV. Non-Compete Clauses Negatively Impact Workers and Their Families;
V. The Proposed Rule Protects Small Businesses and Entrepreneurs; and
VI. The Commission Should Consider a Factor Test for Its Unfairness Analysis for Senior Executive
Factors affecting the number of sentinel lymph nodes removed in patients having surgery for breast cancer
Evaluation of Essential Fatty Acids in Lactating Sow Diets on Sow Reproductive Performance, Colostrum and Milk Composition, and Piglet Survivability
A total of 3,451 mixed parity sows and their litters were used to evaluate the effects of essential fatty acid intake on sow reproductive performance, piglet growth and survivability, and colostrum and milk composition. At approximately d 112 of gestation, sows were blocked by parity within farrowing room and randomly assigned to 1 of 4 experimental treatments. Lactation diets were corn-soybean meal-wheat-based and included 0.5 (Control) or 3% choice white grease (CWG), 3% soybean oil (SO), or a combination of 3% soybean oil and 2% choice white grease (Combination). Thus, sows were provided diets with low essential fatty acid (EFA; as linoleic [LA] and α-linolenic acid [ALA]) in diets with choice white grease or high EFA in diets with soybean oil. Prior to farrowing, sows were provided 4 lb/d of their assigned lactation diet and then allowed ad libitum access after parturition. Overall lactation ADFI increased (P \u3c 0.001) when sows were fed the Combination and CWG treatments compared to sows fed the Control or diet with 3% SO. Regardless of differences among ADFI, daily LA and ALA intake of sows assigned to the Combination and SO treatments were greater (P \u3c 0.001) than sows fed diets with lower EFA provided as CWG. There was no effect of sow EFA intake on piglet survivability from birth to 24 h or from 24 h to weaning (P \u3e 0.10). Overall, sows consuming high EFA provided in the Combination and SO diets produced litters with greater (P \u3c 0.05) litter gain and litter ADG during the lactation period and heavier (P \u3c 0.001) piglet weaning weights when compared to litters from sows fed diets with low EFA provided through CWG. Lactation diet EFA composition did not influence colostrum or milk dry matter, crude protein, or crude fat content (P \u3e 0.10). However, LA and ALA content in both colostrum and milk at weaning increased (P \u3c 0.05) in response to increased EFA levels in diets that contained SO. There was no evidence for differences (P \u3e 0.10) in wean-to-estrus interval, percentage of sows bred by d 7, percentage of sows bred by d 12, farrowing rate, or subsequent farrowing performance due to sow lactation EFA intake. In conclusion, increased LA and ALA intake during the lactation period from soybean oil addition increased overall litter growth and average weaning weights of pigs but did not affect piglet survivability or subsequent reproductive performance of sows
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