2,072 research outputs found
Mapping the ultrafast flow of harvested solar energy in living photosynthetic cells
Photosynthesis transfers energy efficiently through a series of antenna complexes to the
reaction center where charge separation occurs. Energy transfer in vivo is primarily monitored
by measuring fluorescence signals from the small fraction of excitations that fail to
result in charge separation. Here, we use two-dimensional electronic spectroscopy to follow
the entire energy transfer process in a thriving culture of the purple bacteria, Rhodobacter
sphaeroides. By removing contributions from scattered light, we extract the dynamics of
energy transfer through the dense network of antenna complexes and into the reaction
center. Simulations demonstrate that these dynamics constrain the membrane organization
into small pools of core antenna complexes that rapidly trap energy absorbed by surrounding
peripheral antenna complexes. The rapid trapping and limited back transfer of these excitations
lead to transfer efficiencies of 83% and a small functional light-harvesting unit
Bottom Effect in Atomic Force Microscopy Nanomechanics
In this work, the influence of the rigid substrate on the determination of the sample Young''s modulus, the so-called bottom-effect artifact, is demonstrated by an atomic force microscopy force-spectroscopy experiment. The nanomechanical properties of a one-component supported lipid membrane (SLM) exhibiting areas of two different thicknesses are studied: While a standard contact mechanics model (Sneddon) provides two different elastic moduli for these two morphologies, it is shown that Garcia''s bottom-effect artifact correction yields a unique value, as expected for an intrinsic material property. Remarkably, it is demonstrated that the ratio between the contact radius (and not only the indentation) and the sample thickness is the key parameter addressing the relevance of the bottom-effect artifact. The experimental results are validated by finite element method simulations providing a solid support to Garcia''s theory. The amphiphilic nature of the investigated material is representative of several kinds of lipids, suggesting that the results have far reaching implications for determining the correct Young''s modulus of SLMs. The generality of Garcia''s bottom-effect artifact correction allows its application to every kind of supported soft film
Methylthiolate-induced reconstruction of Ag(1 1 1): A medium energy ion scattering study
Medium energy ion scattering (MEIS), using 100 keV H+ incident ions, has been used to investigate the structure of the Ag(1 1 1)(√7 × √7)R19° –CH3S surface phase. The results provide the first direct evidence that this structure does involve substantial reconstruction of the Ag surface layer. The measured absolute scattered ion yields and blocking curves are in generally good agreement with a specific structural model of the surface based on a reconstructed layer containing 3/7 ML Ag atoms, previously suggested on the basis of scanning tunnelling microscopy (STM) and normal incidence X-ray standing wave (NIXSW) studies. However, the MEIS data indicate that any rumpling of the thiolate layer, is small, and probably 0.2 Å. This value is smaller than the amplitude suggested in the STM and NIXSW studies, but could be entirely consistent with the earlier experimental data
Degenerative mitral valve disease: Survival of dogs attending primary-care practice in england
Influence of heavy modes on perturbations in multiple field inflation
We investigate linear cosmological perturbations in multiple field
inflationary models where some of the directions are light while others are
heavy (with respect to the Hubble parameter). By integrating out the massive
degrees of freedom, we determine the multi-dimensional effective theory for the
light degrees of freedom and give explicitly the propagation matrix that
replaces the effective sound speed of the one-dimensional case. We then examine
in detail the consequences of a sudden turn along the inflationary trajectory,
in particular the possible breakdown of the low energy effective theory in case
the heavy modes are excited. Resorting to a new basis in field space, instead
of the usual adiabatic/entropic basis, we study the evolution of the
perturbations during the turn. In particular, we compute the power spectrum and
compare with the result obtained from the low energy effective theory.Comment: 24 pages, 13 figures; v2 substantial changes in sec.V; v3 matching
the published version on JCA
Expanded Vandermonde powers and sum rules for the two-dimensional one-component plasma
The two-dimensional one-component plasma (2dOCP) is a system of mobile
particles of the same charge on a surface with a neutralising background.
The Boltzmann factor of the 2dOCP at temperature can be expressed as a
Vandermonde determinant to the power . Recent advances in
the theory of symmetric and anti-symmetric Jack polymonials provide an
efficient way to expand this power of the Vandermonde in their monomial basis,
allowing the computation of several thermodynamic and structural properties of
the 2dOCP for values up to 14 and equal to 4, 6 and 8. In this
work, we explore two applications of this formalism to study the moments of the
pair correlation function of the 2dOCP on a sphere, and the distribution of
radial linear statistics of the 2dOCP in the plane
Quantification of a lubricant transfer process that enhances the sliding life of a MoS2 coating
Exhaustion of the CD8+ T cell compartment in patients with mutations in phosphoinositide 3-kinase delta
Pathogenic gain-of-function mutations in the gene encoding phosphoinositide 3-kinase delta (PI3Kδ) cause activated PI3Kδ syndrome (APDS), a disease characterized by humoral immunodeficiency, lymphadenopathy, and an inability to control persistent viral infections including Epstein-Barr virus (EBV) and cytomegalovirus (CMV) infections. Understanding the mechanisms leading to impaired immune response is important to optimally treat APDS patients. Immunosenescence of CD8+ T cells was suggested to contribute to APDS pathogenesis. However, the constitutive activation of T cells in APDS may also result in T cell exhaustion. Therefore, we studied exhaustion of the CD8+ T cell compartment in APDS patients and compared them with healthy controls and HIV patients, as a control for exhaustion. The subset distribution of the T cell compartment of APDS patients was comparable with HIV patien
BINGO: A code for the efficient computation of the scalar bi-spectrum
We present a new and accurate Fortran code, the BI-spectra and
Non-Gaussianity Operator (BINGO), for the efficient numerical computation of
the scalar bi-spectrum and the non-Gaussianity parameter f_{NL} in single field
inflationary models involving the canonical scalar field. The code can
calculate all the different contributions to the bi-spectrum and the parameter
f_{NL} for an arbitrary triangular configuration of the wavevectors. Focusing
firstly on the equilateral limit, we illustrate the accuracy of BINGO by
comparing the results from the code with the spectral dependence of the
bi-spectrum expected in power law inflation. Then, considering an arbitrary
triangular configuration, we contrast the numerical results with the analytical
expression available in the slow roll limit, for, say, the case of the
conventional quadratic potential. Considering a non-trivial scenario involving
deviations from slow roll, we compare the results from the code with the
analytical results that have recently been obtained in the case of the
Starobinsky model in the equilateral limit. As an immediate application, we
utilize BINGO to examine of the power of the non-Gaussianity parameter f_{NL}
to discriminate between various inflationary models that admit departures from
slow roll and lead to similar features in the scalar power spectrum. We close
with a summary and discussion on the implications of the results we obtain.Comment: v1: 5 pages, 5 figures; v2: 35 pages, 11 figures, title changed,
extensively revised; v3: 36 pages, 11 figures, to appear in JCAP. The BINGO
code is available online at
http://www.physics.iitm.ac.in/~sriram/bingo/bingo.htm
Optimal bispectrum constraints on single-field models of inflation
We use WMAP 9-year bispectrum data to constrain the free parameters of an 'effective field theory' describing fluctuations in single-field inflation. The Lagrangian of the theory contains a finite number of operators associated with unknown mass scales. Each operator produces a fixed bispectrum shape, which we decompose into partial waves in order to construct a likelihood function. Based on this likelihood we are able to constrain four linearly independent combinations of the mass scales. As an example of our framework we specialize our results to the case of 'Dirac-Born-Infeld' and 'ghost' inflation and obtain the posterior probability for each model, which in Bayesian schemes is a useful tool for model comparison. Our results suggest that DBI-like models with two or more free parameters are disfavoured by the data by comparison with single parameter models in the same class
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