220 research outputs found
La resolución de problemas, mucho más que un eslogan
En el saco de las metodologías activas, participativas y sociales se introduce, normalmente, todo lo que no sea clase tradicional, sea lo que sea a lo que se refiera ese término. Especialmente, se meten acrónimos, términos anglosajones y, últimamente, cualquier cosa con el adjetivo emocional o el prefijo «neuro». Un clásico de las metodologías activas es el flipped learning. ¿Es realmente tan innovadora esta metodología? Como señalan Arce, Conejo y Muñoz-Escolano (2019), al margen del elemento tecnológico, la clase invertida asume algunas de las prácticas habituales de la enseñanza tradicional. Por ejemplo, tal como señalan estos autores, que el contenido tiene que ser explicitado antes de que el alumnado aborde la tarea, sin reservar momentos a su construcción, exploración o aparición como solución óptima ante un problema que le sirva como razón de ser. ¿Enseñar para después aplicar a problemas o enseñar a través de la resolución de problemas? Para nosotros, este segundo enfoque sería la auténtica revolución en la clase de matemáticas. Esto sí que invertiría las clases «tradicionales»..
Local lung immune response to mycobacterium bovis challenge after BCG and M. Bovis heat-inactivated vaccination in European Badger (meles meles)
Tuberculosis (TB) vaccination could be used as a key part of integrated strategies for the disease’s control if an effective and safe vaccine under field conditions is obtained. Recent studies in Spain have evaluated the protective efficacy of two oral vaccines against experimental challenge with live intra-bronchial Mycobacterium bovis in captive badgers: the live-attenuated M. bovis BCG vaccine (Danish strain) and a heat-inactivated M. bovis (HIMB) vaccine. With the objective of increasing the knowledge of the cellular development progress of infection and generating further tools to discriminate between mild and severe TB lesions between and within animals, the immunopathology of tuberculous lesions was studied to characterize the local immune response (cell type profile) within lung granulomas from control (non-vaccinated), BCG vaccinated and HIMB-vaccinated experimentally infected badgers with M. bovis. Four immunohistochemical protocols, for the specific detection of macrophages, T lymphocytes, B lymphocytes and plasma cells within TB granulomas in formalin fixed sections of the right middle lung lobe (lobe targeted for the M. bovis delivery), were performed. Immunolabelled sections were scanned and five randomly selected areas were analyzed with digital image analysis software. The results were expressed as the proportion of the positively immunolabelled area within the total area of the selected site. Data was analyzed using the statistical analysis software (SAS). In the three treatment groups, macrophages were the most abundant inflammatory cells within the granulomas, followed by B lymphocytes and plasma cells. T lymphocyes were absent in those granulomas. This would suggest a predominance of a non-specific innate response mediated by phagocytic cells over an adaptative humoral immune response. The proportion of macrophages and plasma cells was higher in BCG and HIMB-vaccinated badgers, respectively, suggesting the establishment of an adaptative humoral response in HIMB-vaccinated badgers. The lower bacterial load at the lung level, as well as the volume of lesions in lungs using magnetic resonance imaging in badgers with the HIMB vaccine in relation with local immune response presented, must be highlighted, since it would be an advantage in favor of its use under field conditions in terms of reducing TB transmission and environmental contamination.This work has been funded by Ministerio de Ciencia, Innovación y Universidades (MCIU) and the
Agencia Estatal de Investigación (AEI) reference project RTI2018-096010-B-C21 (FEDER co-funded) and, by PCTI
2018–2020 (GRUPIN: IDI2018-000237) and FEDER. Ms. Cristina Blanco Vázquez was granted with a predoctoral
fellowship funded by INIA-CCAA (FPI-INIA) (2018 call). Ms. Ileana Z. Martínez was supported by a Fundación
Carolina PhD scholarship (2017 call). We have received funds by RTI2018-096010-B-C21 (FEDER co-funded) to
cover publication costs
Precise measurement of the top quark mass in the dilepton channel at D0
We measure the top quark mass (mt) in ppbar collisions at a center of mass
energy of 1.96 TeV using dilepton ttbar->W+bW-bbar->l+nubl-nubarbbar events,
where l denotes an electron, a muon, or a tau that decays leptonically. The
data correspond to an integrated luminosity of 5.4 fb-1 collected with the D0
detector at the Fermilab Tevatron Collider. We obtain mt = 174.0 +- 1.8(stat)
+- 2.4(syst) GeV, which is in agreement with the current world average mt =
173.3 +- 1.1 GeV. This is currently the most precise measurement of mt in the
dilepton channel.Comment: 7 pages, 4 figure
Measurement of the semileptonic charge asymmetry in B0 meson mixing with the D0 detector
We present a measurement of the semileptonic mixing asymmetry for B0 mesons,
a^d_{sl}, using two independent decay channels: B0 -> mu+D-X, with D- ->
K+pi-pi-; and B0 -> mu+D*-X, with D*- -> antiD0 pi-, antiD0 -> K+pi- (and
charge conjugate processes). We use a data sample corresponding to 10.4 fb^{-1}
of ppbar collisions at sqrt(s) = 1.96 TeV, collected with the D0 experiment at
the Fermilab Tevatron collider. We extract the charge asymmetries in these two
channels as a function of the visible proper decay length (VPDL) of the B0
meson, correct for detector-related asymmetries using data-driven methods, and
account for dilution from charge-symmetric processes using Monte Carlo
simulation. The final measurement combines four signal VPDL regions for each
channel, yielding a^d_{sl} = [0.68 \pm 0.45 \text{(stat.)} \pm 0.14
\text{(syst.)}]%. This is the single most precise measurement of this
parameter, with uncertainties smaller than the current world average of B
factory measurements.Comment: Version includes minor textual changes following peer review by
journal, most notably the updating of Ref. [21] to reflect the most recent
publicatio
Direct measurement of the mass difference between top and antitop quarks
We present a direct measurement of the mass difference between top and
antitop quarks (dm) in lepton+jets top-antitop final states using the "matrix
element" method. The purity of the lepton+jets sample is enhanced for
top-antitop events by identifying at least one of the jet as originating from a
b quark. The analyzed data correspond to 3.6 fb-1 of proton-antiproton
collisions at 1.96 TeV acquired by D0 in Run II of the Fermilab Tevatron
Collider. The combination of the e+jets and mu+jets channels yields dm = 0.8
+/- 1.8 (stat) +/- 0.5 (syst) GeV, which is in agreement with the standard
model expectation of no mass difference.Comment: submitted to Phys. Rev.
Search for new fermions ("quirks") at the Fermilab Tevatron Collider
We report results of a search for particles with anomalously high ionization
in events with a high transverse energy jet and large missing transverse energy
in fb of integrated luminosity collected by the D0 experiment at
the Fermilab Tevatron collider. Production of such particles
(quirks) is expected in scenarios with extra QCD-like {\it SU(N)} sectors, and
this study is the first dedicated search for such signatures. We find no
evidence of a signal and set a lower mass limit of 107 ~GeV for the mass of a
charged quirk with strong dynamics scale in the range from 10 keV to
1 MeV.Comment: submitted to Phys. Rev. Letter
Measurement of the top quark pair production cross section in the lepton+jets channel in proton-antiproton collisions at =1.96 TeV
We present a measurement of the inclusive top quark pair production cross
section in \ppbar collisions at (\sqrt{s}=1.96) TeV utilizing data
corresponding to an integrated luminosity of \lumi\ collected with the D0
detector at the Fermilab Tevatron Collider. We consider final states containing
one high- isolated electron or muon and at least two jets, and we
perform three analyses: one exploiting specific kinematic features of \ttbar
events, the second using -jet identification, and the third using both
techniques to separate \ttbar\ signal from background. In the third case, we
determine simultaneously the cross section and the ratio of the
production rates of +heavy flavor jets and +light flavor jets, which
reduces the impact of the systematic uncertainties related to the background
estimation. Assuming a top quark mass of 172.5 GeV, we obtain
pb. This result agrees with
predictions of the standard model.Comment: 19 pages, 6 figures, submitted to Phys. Rev.
Measurements of single top quark production cross sections and |Vtb| in ppbar collisions at sqrt{s}=1.96 TeV
We present measurements of production cross sections of single top quarks in
\ppbar collisions at in a data sample corresponding
to an integrated luminosity of collected by the D0 detector
at the Fermilab Tevatron Collider. We select events with an isolated electron
or muon, an imbalance in transverse energy, and two, three, or four jets, with
one or two of them containing a bottom hadron. We obtain an inclusive cross
section of \sigma({\ppbar}{\rargap}tb+X, tqb+X) = 3.43\pm^{0.73}_{0.74}\;\rm
pb and use it to extract the CKM matrix element at
the 95% C.L. We also measure \sigma({\ppbar}{\rargap}tb+X) =
0.68\pm^{0.38}_{0.35}\;\rm pb and \sigma({\ppbar}{\rargap}tqb+X) =
2.86\pm^{0.69}_{0.63}\;\rm pb when assuming, respectively, and
production rates as predicted by the standard model.Comment: 11 pages, 8 figures, submitted to Phys. Rev.
Evidence for an anomalous like-sign dimuon charge asymmetry
We measure the charge asymmetry A of like-sign dimuon events in 6.1 fb(-1) of p (p) over bar collisions recorded with the D0 detector at a center-of-mass energy root s = 1.96 TeV at the Fermilab Tevatron collider. From A, we extract the like-sign dimuon charge asymmetry in semileptonic b-hadron decays: A(sl)(b) = -0.00957 +/- 0.00251 (stat) +/- 0.00146 (syst). This result differs by 3.2 standard deviations from the standard model prediction A(sl)(b)(SM) = (-2.3(0.6)(+0.5)) x 10(-4) and provides first evidence of anomalous CP violation in the mixing of neutral B mesons
Search for sneutrino production in emu final states in 5.3 fb^-1 of ppbar collisions at sqrt(s) =1.96 TeV
We report the results of a search for R parity violating (RPV) interactions
leading to the production of supersymmetric sneutrinos decaying into emu final
states using 5.3 fb^-1 of integrated luminosity collected by the D0 experiment
at the Fermilab Tevatron Collider. Having observed no evidence for production
of emu resonances, we set direct bounds on the RPV couplings lambda^'_311 and
lambda_312 as a function of sneutrino mass.Comment: 7 pages, 6 figures. To be submitted to Phys. Rev. Let
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