Разбирање на здравствениот контекст за имплементација на нова дигитална психосоцијална интервенција за подобрување на менталното здравје во Северна Македонија

The aim of this study was to identify the contextual attributes in North Macedonia and their characteristics relevant to the implementation of a new digital intervention to improve mental health, called DIALOG+. This research is the first of its kind in North Macedonia due to the analysis of contextual attributes that may affect the effectiveness of the intervention and its acceptability in various settings of mental health care. Some of the data processed in this paper were provided and analyzed by the National Mental Health Strategy 2018-2025 and other relevant accompanying documents from the World Health Organization and action plans, as well as through interviews with stakeholders (patients, carers, clinicians and policy makers) for their opinion before introducing the DIALOG + intervention and the report on the assessment of the situation in the centers where the implementation of the intervention should have started. The collected data were then mapped to a framework developed by the Ottawa Implementation Group, which included 14 contextual attributes. The results are summarized in 2 subgroups, and are presented as facilitators and barriers to implementation, specific to the mental health system in North Macedonia. The characteristics of DIALOG + (widely applicable psychosocial intervention) are in accordance with modern assumptions for psychosocial rehabilitation of patients with psychosis. Hence, we can conclude that it is a useful tool for professionals in monitoring and achieving the true vision and mission of these institutions. It will help patients reintegrate into society, become more independent and use their full potential in the pursuit of healthy and functional living.Целта на оваа студија беше да ги идентификува контекстуалните атрибути во Северна Македонија и нивните карактеристики релевантни за спроведување на нова дигитална интервенција за подобрување на менталното здравје, наречена DIALOG+.  Ова истражување е прво од ваков вид во Северна Македонија поради анализата на контекстуалните атрибути што може да влијаат на ефективноста на интервенцијата и на нејзината прифатливост во различни поставки на здравствената заштита на менталното здравје. Дел од податоците обработени во овој труд се обезбедени и анализирани од Националната стратегија за ментално здравје 2018-2025 и други соодветни придружни документи од Светската здравствена организација и акциски планови, како и преку интервјуа со засегнатите страни (пациенти, негуватели, клиничари и креатори на политики) за нивното мислење пред воведување на интервенцијата DIALOG+ и извештајот за проценка на состојбата во центрите каде требаше да се започне со имплементирање на интервенцијата. Потоа, собраните податоци беа мапирани на рамката развиена од Групата за имплементација на Отава, која вклучува 14 контекстуални атрибути. Резултатите беа сумирани во 2 подгрупи, и се прикажани како фацилитатори и бариери за спроведување, специфични за ментално-здравствениот систем во Северна Македонија. Карактеристиките на DIALOG+ (широко применлива психосоцијална интервенција) се во согласност со современите претпоставки за психосоцијална рехабилитација на пациенти со психоза. Оттука, може да заклучиме дека претставува корисна алатка за професионалците во следење и остварување на вистинската визија и мисија на овие установи. Тоа ќе им помогне на пациентите да се реинтегрираат во општеството, да станат понезависни и да ги искористат своите целосни капацитети во потрага по здравствено и функционално живеење

Mental Health Legislation and Involuntary Hospitalization in the Republic of Macedonia

As psychiatrists, we are often obliged to provide non-consensual treatment. This institute comprises the rights of the patients with mental health disorders. The aim of this paper is to explain the contemporary mental health legislation in our country the Republic of Macedonia and the problems with the implementation of involuntary hospitalisation. This could be overcome with close cooperation between the judicial and health care system

Rare Pathogenic Copy Number Variation in the 16p11.2 (BP4–BP5) Region Associated with Neurodevelopmental and Neuropsychiatric Disorders: A Review of the Literature

Copy number variants (CNVs) play an important role in the genetic underpinnings of neuropsychiatric/neurodevelopmental disorders. The chromosomal region 16p11.2 (BP4-BP5) harbours both deletions and duplications that are associated in carriers with neurodevelopmental and neuropsychiatric conditions as well as several rare disorders including congenital malformation syndromes. The aim of this article is to provide a review of the current knowledge of the diverse neurodevelopmental disorders (NDD) associated with 16p11.2 deletions and duplications reported in published cohorts. A literature review was conducted using the PubMed/MEDLINE electronic database limited to papers published in English between 1 January 2010 and 31 July 2020, describing 16p11.2 deletions and duplications carriers' cohorts. Twelve articles meeting inclusion criteria were reviewed from the 75 articles identified by the search. Of these twelve papers, eight described both deletions and duplications, three described deletions only and one described duplications only. This study highlights the heterogeneity of NDD descriptions of the selected cohorts and inconsistencies concerning accuracy of data reporting.info:eu-repo/semantics/publishedVersio

Predictors and moderators of outcome of psychotherapeutic interventions for mental disorders in adolescents and young adults : protocol for systematic reviews

Background: Adolescence and young adulthood is a risk period for the emergence of mental disorders. There is strong evidence that psychotherapeutic interventions are effective for most mental disorders. However, very little is known about which of the different psychotherapeutic treatment modalities are effective for whom. This large systematic review aims to address this critical gap within the literature on non-specific predictors and moderators of the outcomes of psychotherapeutic interventions among adolescents and young adults with mental disorders. Methods: The protocol is being reported in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) Statement. PubMed and PsycINFO databases will be searched for randomized controlled and quasi-experimental/naturalistic clinical trials. Risk of bias of all included studies will be assessed by the Mixed Methods Appraisal Tool. The quality of predictor and moderator variables will be also assessed. A narrative synthesis will be conducted for all included studies. Discussion: This systematic review will strengthen the evidence base on effective mental health interventions for young people, being the first to explore predictors and moderators of outcome of psychotherapeutic interventions for a wide range of mental disorders in young people.Peer reviewe

Dual training as clinician-scientist in child and adolescent psychiatry : are we there yet?

Peer reviewe

Attitudes of the autism community to early autism research

Investigation into the earliest signs of autism in infants has become a significant sub-field of autism research. This work invokes specific ethical concerns such as: use of ‘at-risk’ language; communicating study findings to parents; and the future perspective of enrolled infants when they reach adulthood. The current study aimed to ground this research field in an understanding of the perspectives of members of the autism community. Following focus groups to identify topics, an online survey was distributed to autistic adults, parents of children with autism, and practitioners in health and education settings across eleven European countries. Survey respondents (n=2317) were positively disposed towards early autism research and there was significant overlap in their priorities for the field, and preferred language to describe infant research participants. However there were also differences including overall less favourable endorsement of early autism research by autistic adults relative to other groups and a dislike of the phrase ‘at-risk’ to describe infant participants, in all groups except healthcare practitioners. The findings overall indicate that the autism community in Europe is supportive of early autism research. Researchers should endeavour to maintain this by continuing to take community perspectives into account

Forensic mental health in Europe: some key figures

Purpose. While the number of forensic beds and the duration of psychiatric forensic psychiatric treatment have increased in several European Union (EU) states, this is not observed in others. Patient demographics, average lengths of stay and legal frameworks also differ substantially. The lack of basic epidemiological information on forensic patients and of shared indicators on forensic care within Europe is an obstacle to comparative research. The reasons for such variation are not well understood. Methods. Experts from seventeen EU states submitted data on forensic bed prevalence rates, gender distributions and average length of stay in forensic in-patient facilities. Average length of stay and bed prevalence rates were examined for associations with country-level variables including Gross Domestic Product (GDP), expenditure on healthcare, prison population, general psychiatric bed prevalence rates and democracy index scores. Results. The data demonstrated substantial differences between states. Average length of stay was approximately ten times greater in the Netherlands than Slovenia. In England and Wales, 18% of patients were female compared to 5% in Slovenia. There was a 17-fold difference in forensic bed rates per 100,000 between the Netherlands and Spain. Exploratory analyses suggested average length of stay was associated with GDP, expenditure on healthcare and democracy index scores. Conclusion. The data presented in this study represent the most recent overview of key epidemiological data in forensic services across seventeen EU states. However, systematically collected epidemiological data of good quality remain elusive in forensic psychiatry. States need to develop common definitions and recording practices and contribute to a publicly available database of such epidemiological indicators

Оrganizational attention deficit as sustainability indicator: assessment and management

<p>The aim of this paper is to contribute towards dealing with the attention indicator in a standard Pressure-State-Response (PSR) framework of sustainable development. Hence, the daily information overflow is identified as a pressure variable adversely affecting the attention. This is manifested by an increased likelihood of missing key information when making decisions, diminished time for attentive reflection, difficulty in holding others’ attention, as well as by decreased ability to focus when necessary, which are symptoms of the so-called organizational attention deficit disorder - OADD. As to the state variable there were combined techniques from cognitive neuroscience and applied sciences in order to objectively measure the incidence of OADD. In particular, the use of neuropsychological procedures for objective assessment of OADD will be summarized. Namely, few attention diagnostic tests of the Amsterdam Neuropsychological Tasks Program (ANT) will be considered for determining the focused, shifted and sustained attention. As intervention measure attention strengthening techniques is applied. In particular, in research were proposed the neurofeedback technique as response variable and have shown its effectiveness in coping with the OADD. This approach represents a new perspective in social psychophysiology and expands the potential applications of ANT and neurofeedback methodology.</p><p> </p

Модулација на електрични мозочни осцилации (МЕМО)

Креирање на модели на машинско учење, со цел класифицирање на возрасни со Attention Deficit Hyperactivity Disorder (ADHD), врз основа на QEEG (Quantitative EEG) анализа