Estrategias de comunicación para promover el potencial turístico de la Laguna de Conache del distrito de Laredo – departamento de La Libertad - 2016

El presente estudio se ha realizado con el propósito de elaborar estrategias de comunicación para promover el potencial turístico de la laguna de Conache del Distrito de Laredo – Departamento de la Libertad - 2016”. Por tal motivo, el objetivo del siguiente informe consiste en Identificar el potencial turístico que existe en la laguna de Conache del Distrito de Laredo. Para ver la situación actual posteriormente elaborar el plan de comunicación de marketing. Han participado en la investigación 266 visitantes a los cuales se les aplico un cuestionario que ha permitido conocer la opinión de los mismos con respecto a las variables de estudio, así mismo se ha utilizado el diseño de contrastación de una sola casilla de tipo no experimental transversal de un solo grupo, para el análisis de los datos se ha utilizado la estadística descriptiva Los resultados de la investigación ha permitido conocer el potencial turístico que posee la Laguna de Conache siendo este bastante alto, y apropiado para desarrollar el turismo rural, turismo de aventura, el ecoturismo, el turismo gastronómico y el turismo cultural, sin embargo carece de servicios que cubran las necesidades básicas que permitan el disfrute de los recursos turísticos como hoteles, restaurantes, transporte, servicios de guía, etc., sin embargo los rubros más demandados son los deportes de aventura como sandboarding, tirolesa y palestra, seguido del paisaje que contiene el lugar. Por lo cual se considera oportuno y eficaz, impulsar considerablemente el desarrollo de una estrategia de comunicación para promover el potencial turístico de la laguna de Conache del Distrito de Laredo, Departamento de La Libertad, que involucre en primera instancia a los pobladores aledaños a ella a fin de que se vayan generando iniciativas empresariales orientadas a mejorar su calidad de vida y la de sus familias y en segunda instancia con los gobiernos local, regional y PROMPERU. Estrategia de comunicación que finalmente impulsara la demanda de turistas nacionales e internacionalesThis study was conducted in order to develop communication strategies to promote the tourism potential of Lake District Conache Laredo - Department of Freedom - 2016 ". Therefore, the aim of this report is to identify the tourism potential that exists in the lagoon Conache Laredo District. To view the current situation subsequently develop the marketing communication plan. They have participated in research 266 visitors who were applied a questionnaire that has allowed to know the opinion of the same with respect to the study variables, also has been used to design contrasting one-box type no experimental cross one group for data analysis was used descriptive statistics The results of the research has revealed the tourist potential that owns the Laguna Conache this being quite high, and appropriate for developing rural tourism, adventure tourism, eco-tourism, gastronomic tourism and cultural tourism, however lacks services covering the basic needs that allow the enjoyment of tourist resources such as hotels, restaurants, transportation, guide services, etc., however the most popular items are the adventure sports like sandboarding, zip line and palestra, followed landscape containing the place. Therefore it is considered appropriate and effective, greatly promote the development of a communications strategy to promote the tourism potential of Lake Conache District Laredo, Department of La Libertad, involving in the first instance to the surrounding villagers to it so that they are generated business initiatives aimed at improving their quality of life and that of their families and secondly with local, regional and PROMPERU governments. Communication strategy that ultimately will boost demand for domestic tourists and internationalTesi

Conocimientos y actitudes sobre requerimientos nutricionales durante el embarazo en gestantes del I trimestre. Hospital Belén de Trujillo año 2012.

Con el objetivo de determinar el nivel de conocimientos y actitudes sobre requerimientos nutricionales durante el embarazo en gestantes del I trimestre. Hospital Belén de Trujillo año 2012; se realizó un estudio descriptivo, retrospectivo de corte transversal, en 115 gestantes en el I trimestre; para lo cual se elaboró una encuesta semi estructurada, para medir los conocimientos sobre requerimientos nutricionales a través de diez preguntas con tres alternativas cada uno de ellas y otra sección sobre actitudes en requerimientos nutricionales que constó de 10 preguntas con 5 alternativas. Encontrándose que el 40% de las encuestadas tuvieron un nivel de conocimiento medio; un 36% de las encuestadas tuvieron un nivel de conocimiento alto; y un 24% se encuentran en un nivel de conocimiento bajo. Las gestantes señalaron el tipo de alimentos correcto para proteínas en un 63%, 71% para calcio; 63% en vitamina A; 83% en sulfato ferroso; 65% de hierro; 73% de zinc; 70% de ácido fólico y tan solo conocen en 54% los alimentos que aportan fibra y llama la atención que solo conocen 35% los alimentos que proporcionan vitamina B6.El nivel de actitud sobre el requerimiento se encontró que el 70% de las encuestadas tuvieron un nivel de actitud adecuado; el 25% se encuentra en un nivel de actitud neutral y un 5% se encuentran en un nivel de actitud inadecuado.In order to determine the level of knowledge and attitudes about nutritional requirements during pregnancy in pregnant the first quarter. Hospital Belen de Trujillo 2012; A descriptive, retrospective cross-sectional study was conducted on 115 pregnant women in the first quarter; for which a semi structured questionnaire was developed to measure knowledge about nutritional requirements through ten questions with three alternatives each of them and another section on attitudes nutritional requirements that consisted of 10 questions with five alternatives. Finding that 40% of respondents had an average level of knowledge; 36% of respondents had a high level of knowledge; and 24% are at a low level of knowledge. Pregnant said the right kind of food proteins by 63%, 71% for calcium; 63% vitamin A; 83% ferrous sulfate; 65% iron; 73% zinc; 70% of folic acid and only 54% know the foods that provide fiber and striking that only 35% know the foods that provide vitamin B6. The level of attitude towards the requirement was found that 70% of respondents had an adequate standard of attitude; 25% is in a neutral level attitude and 5% are at a level of improper attitude.Tesi

Neutrophil extracellular trap inhibition increases inflammation, bacteraemia and mortality in murine necrotizing enterocolitis

Necrotizing enterocolitis (NEC) is a devastating gastrointestinal disease affecting primarily premature infants. The disease is characterized by intestinal inflammation and leucocyte infiltration, often progressing to necrosis, perforation, systemic inflammatory response and death. Neutrophil extracellular traps (NETs), denoting nuclear DNA, histone and antimicrobial protein release, have been suggested to play a role in NEC. This study aimed to determine the role of NETs in NEC and explore the effect of chloramidine, a NET inhibitor, on a murine NEC-like intestinal injury model. Blood and intestinal tissues were collected from infants diagnosed with ≥ Stage II NEC, and levels of nucleosomes and NETs, respectively, were compared with those of case-matched controls. In mice, NEC was induced with dithizone/Klebsiella, and mice in the treatment group received 40 mg/kg chloramidine. Bacterial load, intestinal histology, plasma myeloperoxidase and cytokine levels, and immunofluorescent staining were compared with controls. Nucleosomes were significantly elevated in both human and mouse NEC plasma, whereas NET staining was only present in NEC tissue in both species. Chloramidine treatment increased systemic inflammation, bacterial load, organ injury and mortality in murine NEC. Taken together, our findings suggest that NETs are critical in the innate immune defence during NEC in preventing systemic bacteraemia

“Influencia en la aplicación de la metodología en el proceso de aprendizaje en estudiantes del nivel medio ciclo básico de los Institutos Nacionales, muestra representativa de los municipios de Cuyotenango, San Gabriel, Sto. Domingo, San Bernandino, Samayac y San Francisco Zapotitlán del departamento de Suchitepéquez”.

El desarrollo de una nación está determinado por los niveles educativos alcanzados, así como la influencia que tienen cada uno de los elementos que se desarrollan y llevan a la educación a cada uno de los lugares del país. Un elemento indispensable dentro del rol educativo es, el docente quien tiene como papel fundamental la aplicación de metodologías para que estas sean absorbidas y luego reflejadas en el proceso de aprendizaje del alumno. Por ello debe mantenerse de forma activa y actualizada, conociendo los procesos actuales, para que con dedicación y esmero impartan sus clases y así el alumno pueda llevar a cabo lo aprendido siendo de manera significativa y con sentido común. El presente informe es del seminario sobre “Influencia en la aplicación de la metodología constructivista en el proceso de aprendizaje de estudiantes del nivel medio ciclo básico de los Institutos Nacionales de Educación Básica, muestra representativa de los municipios de Cuyotenango, San Gabriel, Sto. Domingo, San Bernandino, Samayac y San Francisco Zapotitlán del departamento de Suchitepéquez”. A través del cual se pudo conocer ciertos factores presentes en la educación así como la influencia que estos tienen, además de evidenciar necesidades palpables dentro de las instituciones educativas, para con ello tratar de proponer alternativas que permitan mejorar la calidad educativa. El informe está estructurado en V capítulos; El informe está estructurado en V capítulos; el capítulo I contiene el diseño de investigación dentro del cual están: el problema de investigación, definición del problema, planteamiento del problema, justificación, definición de unidad de análisis, delimitación del problema, objetivos e hipótesis

Cerebrospinal fluid studies in an intensive care nursery

Peer Reviewe

Gut bacteria dysbiosis and necrotising enterocolitis in very low birthweight infants: a prospective case-control study.

BACKGROUND: Gut bacteria might predispose to or protect from necrotising enterocolitis, a severe illness linked to prematurity. In this observational prospective study we aimed to assess whether one or more bacterial taxa in the gut differ between infants who subsequently develop necrotising enterocolitis (cases) and those who do not (controls). METHODS: We enrolled very low birthweight (1500 g and lower) infants in the primary cohort (St Louis Children\u27s Hospital) between July 7, 2009, and Sept 16, 2013, and in the secondary cohorts (Kosair Children\u27s Hospital and Children\u27s Hospital at Oklahoma University) between Sept 12, 2011 and May 25, 2013. We prospectively collected and then froze stool samples for all infants. Cases were defined as infants whose clinical courses were consistent with necrotising enterocolitis and whose radiographs fulfilled criteria for Bell\u27s stage 2 or 3 necrotising enterocolitis. Control infants (one to four per case; not fixed ratios) with similar gestational ages, birthweight, and birth dates were selected from the population after cases were identified. Using primers specific for bacterial 16S rRNA genes, we amplified and then pyrosequenced faecal DNA from stool samples. With use of Dirichlet multinomial analysis and mixed models to account for repeated measures, we identified host factors, including development of necrotising enterocolitis, associated with gut bacterial populations. FINDINGS: We studied 2492 stool samples from 122 infants in the primary cohort, of whom 28 developed necrotising enterocolitis; 94 infants were used as controls. The microbial community structure in case stools differed significantly from those in control stools. These differences emerged only after the first month of age. In mixed models, the time-by-necrotising-enterocolitis interaction was positively associated with Gammaproteobacteria (p=0·0010) and negatively associated with strictly anaerobic bacteria, especially Negativicutes (p=0·0019). We studied 1094 stool samples from 44 infants in the secondary cohorts. 18 infants developed necrotising enterocolitis (cases) and 26 were controls. After combining data from all cohorts (166 infants, 3586 stools, 46 cases of necrotising enterocolitis), there were increased proportions of Gammaproteobacteria (p=0·0011) and lower proportions of both Negativicutes (p=0·0013) and the combined Clostridia-Negativicutes class (p=0·0051) in infants who went on to develop necrotising enterocolitis compared with controls. These associations were strongest in both the primary cohort and the overall cohort for infants born at less than 27 weeks\u27 gestation. INTERPRETATION: A relative abundance of Gammaproteobacteria (ie, Gram-negative facultative bacilli) and relative paucity of strict anaerobic bacteria (especially Negativicutes) precede necrotising enterocolitis in very low birthweight infants. These data offer candidate targets for interventions to prevent necrotising enterocolitis, at least among infants born at less than 27 weeks\u27 gestation. FUNDING: National Institutes of Health (NIH), Foundation for the NIH, the Children\u27s Discovery Institute. Lancet 2016 May 7; 387(10031):1928-3