New Management Discourses: Difussion, impacts and resistances

El presente monográfico de Recerca titulado «Los nuevos discursos del management: contribuciones desde una perspectiva crítica», se compone de siete artículos de investigación y dos recensiones. A través de los diferentes escritos se pretende realizar un recorrido por el estado actual de los discursos del management y sus repercusiones no solo en el mundo del trabajo, sino en el grueso de la sociedad desde una perspectiva crítica. Así pues, a lo largo de las siguientes páginas el/la lector/a podrá transitar por los diferentes discursos que hoy en día caracterizan el espacio social. Nos referimos a marcos generales de sentido como el individualismo y la descolectivización de lo social, pero también a cuestiones más concretas como el emprendimiento y la precariedad; todos ellos componentes que conforman el escenario al que nos estamos remitiendo en todo momento, esto es, el del discurso neoliberal o el «nuevo espíritu del capitalismo» (Boltanski y Chiapello, 2002)

Neoliberal subjectivities in the post-pandemic era: philosophical and sociological reflections

This special issue aims at proposing a reflection on the construction of contemporary subjectivities in a post-pandemic context. The starting point of this editorial project has been the debates linked to the new subjectivities associated with the hegemony of neoliberalism. Within the framework of contemporary societies, neoliberal subjectivities emerge, where individuals incorporate ideas and practices analogous to those of businesses. How does the post-pandemic context affect these subjectivities? According to the claims deployed in the different contributions of this special issue, it might not be mistaken to point out that, despite the future challenges and the impact of the pandemic on a reassessment of the vital projects of citizens, the cultural colonization of neoliberalism is still strongly present in both our societies and even in ourselves.El presente monográfico pretende plantear una reflexión sobre la construcción de las subjetividades contemporáneas en un contexto de pospandemia. El punto de partida en la gestación de este proyecto editorial han sido los debates vinculados a las nuevas subjetividades asociadas a la hegemonía del neoliberalismo. En el marco de las sociedades contemporáneas emergen las subjetividades neoliberales, individuos que, en su conducta cotidiana, incorporan ideas y prácticas análogas a las de las empresas. ¿Cómo afecta el contexto pospandémico a dichas subjetividades? A partir de los argumentos expuestos en las distintas contribuciones de este monográfico, no es imprudente señalar que, pese a los desafíos futuros y el impacto de la pandemia en una reevaluación de los proyectos vitales de los ciudadanos, la colonización cultural del neoliberalismo sigue presente todavía en nuestras sociedades y entre nosotros con mucha, mucha fuerza

Docència per a l’obtenció del certificat de Capacitació en valencià a través dels estudis de Grau de Mestre: assignatures de competència professional

El present article resumeix a grans trets les tasques dutes a terme des de la Xarxa «Docència per a la capacitació en valencià: assignatures de competència professional» (3003), motivades en essència per una sèrie de canvis en la legislació educativa que han obligat a reformular algunes de les assignatures dels itineraris de Capacitació que s’ofereixen dins els plans d’estudis de Mestre de la Facultat d’Educació. En aquestes línies es detalla allò més ressenyable quant al disseny i procés de confecció de les guies docents de dues noves assignatures transversals d’impartició imminent (curs acadèmic 2014-2015) que substituiran el gruix de l’optativitat en valencià impartida pel Departament de Filologia Catalana dins les titulacions de Grau d’Educació Infantil i Grau d’Educació Primària de la Universitat d’Alacant. També s’hi descriu la reorientació d’una altra assignatura ―en aquest cas, de formació bàsica i exclusiva de l’àmbit de l’educació infantil―, arran també dels canvis en l’optativitat adés advertits. En suma: s’hi detalla el seguiment reglat i continuat d’aquests processos per tal de garantir la correcta reestructuració dels continguts i la resta d’elements (requisits lingüístics, pràctiques sense encavallaments, processos de seguiment, criteris d’avaluació, etc.) que integren cada guia docent

Regulatory circuits involving bud dormancy factor PpeDAM6

DORMANCY-ASSOCIATED MADS-BOX (DAM) genes have recently emerged as key potential regulators of the dormancy cycle and climate adaptation in perennial species. Particularly, PpeDAM6 has been proposed to act as a major repressor of bud dormancy release and bud break in peach (Prunus persica). PpeDAM6 expression is downregulated concomitantly with the perception of a given genotype-dependent accumulation of winter chilling time, and the coincident enrichment in H3K27me3 chromatin modification at a specific genomic region. We have identified three peach BASIC PENTACYSTEINE PROTEINs (PpeBPCs) interacting with two GA-repeat motifs present in this H3K27me3- enriched region. Moreover, PpeBPC1 represses PpeDAM6 promoter activity by transient expression experiments. On the other hand, the heterologous overexpression of PpeDAM6 in European plum (Prunus domestica) alters plant vegetative growth, resulting in dwarf plants tending toward shoot meristem collapse. These alterations in vegetative growth of transgenic lines associate with impaired hormone homeostasis due to the modulation of genes involved in jasmonic acid, cytokinin, abscisic acid, and gibberellin pathways, and the downregulation of shoot meristem factors, specifically in transgenic leaf and apical tissues. The expression of many of these genes is also modified in flower buds of peach concomitantly with PpeDAM6 downregulation, which suggests a role of hormone homeostasis mechanisms in PpeDAM6-dependent maintenance of floral bud dormancy and growth repression

Ensenyar valencià com a L2 en l'aula d'Educació Infantil: reformulació metodològica, replantejament didàctic i revisió de continguts

L’article resumeix de forma succinta la revisió densa de l’assignatura “Habilitats comunicatives i lectoescriptura en català” a càrrec de l’equip docent responsable, al cap d’un lustre de bagatge. D’ençà l’entrada en vigor del Pla d’Estudis 2010 del grau de Mestre d’Educació Infantil de la Universitat d’Alacant, aquesta ha estat l’única matèria de formació bàsica de la titulació que integra continguts de didàctica de la llengua oral i escrita circumscrits a l’etapa infantil, amb un procediment metodològic orientat sobretot a l’ensenyament-aprenentatge del valencià com a segona llengua; això és, com a llengua vehicular escolar no familiar (L2). L’actuació, escomesa dins el marc del programa Xarxes d’Investigació en Docència Universitària 2015-2016, ha comportat una reformulació metodològica, un replantejament didàctic i una revisió de continguts ajustada als darrers canvis adoptats pel sistema educatiu en matèria de plurilingüisme. Esqueia l’actualització profunda del temari i de la metodologia docent; la fixació de nous criteris unificats i coherents per al sistema d’avaluació no presencial; i la millora de les pràctiques, amb una proposta definida de bifurcació dels grups de treball. La conversió dels materials i del temari a format Prezi com a recurs didàctic n’ha vertebrat el conjunt de l’actuació

Análisis de campañas de comunicación social

Sisenes Jornades de Foment de la Investigació de la FCHS (Any 2000-2001

Risk factors and outcome of COVID-19 in patients with hematological malignancies

Background: Prognostic factors of poor outcome in patients with hematological malignancies and COVID-19 are poorly defned. Patients and methods: This was a Spanish transplant group and cell therapy (GETH) multicenter retrospective observational study, which included a large cohort of blood cancer patients with laboratory-confrmed SARS-CoV-2 infection through PCR assays from March 1st 2020 to May 15th 2020. Results: We included 367 pediatric and adult patients with hematological malignancies, including recipients of autologous (ASCT) (n=58) or allogeneic stem cell transplantation (allo-SCT) (n=65) from 41 hospitals in Spain. Median age of patients was 64 years (range 1-93.8). Recipients of ASCT and allo-SCT showed lower mortality rates (17% and 18%, respectively) compared to non-SCT patients (31%) (p=0.02). Prognostic factors identifed for day 45 overall mortality (OM) by logistic regression multivariate analysis included age>70 years [odds ratio (OR) 2.1, 95% con‑ fdence interval (CI) 1.2-3.8, p=0.011]; uncontrolled hematological malignancy (OR 2.9, 95% CI 1.6-5.2, p20 mg/dL (OR 3.3, 95% CI 1.7-6.4, p<0.0001). In multivariate analysis of 216 patients with very severe COVID-19, treatment with azithromycin or low dose corticosteroids was associated with lower OM (OR 0.42, 95% CI 0.2-0.89 and OR 0.31, 95% CI 0.11-0.87, respectively, p=0.02) whereas the use of hidroxycloroquine did not show signifcant improvement in OM (OR 0.64, 95% CI 0.37-1.1, P=0.1). Conclusions: In most patients with hematological malignancies COVID-19 mortality was directly driven by older age, disease status, performance status, as well as by immune (neutropenia) parameters and level of infammation (high CRP). Use of azithromycin and low dose corticosteroids may be of value in very severe COVID-19

Impact of interstitial lung disease on the survival of systemic sclerosis with pulmonary arterial hypertension

To assess severity markers and outcomes of patients with systemic sclerosis (SSc) with or without pulmonary arterial hypertension (PAH-SSc/non-PAH-SSc), and the impact of interstitial lung disease (ILD) on PAH-SSc. Non-PAH-SSc patients from the Spanish SSc registry and PAH-SSc patients from the Spanish PAH registry were included. A total of 364 PAH-SSc and 1589 non-PAH-SSc patients were included. PAH-SSc patients had worse NYHA-functional class (NYHA-FC), worse forced vital capacity (FVC) (81.2 ± 20.6% vs 93.6 ± 20.6%, P &lt; 0.001), worse tricuspid annular plane systolic excursion (TAPSE) (17.4 ± 5.2 mm vs 19.9 ± 6.7 mm, P &lt; 0.001), higher incidence of pericardial effusion (30% vs 5.2%, P &lt; 0.001) and similar prevalence of ILD (41.8% vs. 44.9%). In individuals with PAH-SSc, ILD was associated with worse hemodynamics and pulmonary function tests (PFT). Up-front combination therapy was used in 59.8% and 61.7% of patients with and without ILD, respectively. Five-year transplant-free survival rate was 41.1% in PAH-SSc patients and 93.9% in non-PAH-SSc patients (P &lt; 0.001). Global survival of PAH-SSc patients was not affected by ILD regardless its severity. The multivariate survival analysis in PAH-SSc patients confirmed age at diagnosis, worse NYHA-FC, increased PVR, reduced DLCO, and lower management with up-front combination therapy as major risk factors. In conclusion, in PAH-SSc cohort risk of death was greatly increased by clinical, PFT, and hemodynamic factors, whereas it was decreased by up-front combination therapy. Concomitant ILD worsened hemodynamics and PFT in PAH-SSc but not survival regardless of FVC impairment

Impact of interstitial lung disease on the survival of systemic sclerosis with pulmonary arterial hypertension

To assess severity markers and outcomes of patients with systemic sclerosis (SSc) with or without pulmonary arterial hypertension (PAH-SSc/non-PAH-SSc), and the impact of interstitial lung disease (ILD) on PAH-SSc. Non-PAH-SSc patients from the Spanish SSc registry and PAH-SSc patients from the Spanish PAH registry were included. A total of 364 PAH-SSc and 1589 non-PAH-SSc patients were included. PAH-SSc patients had worse NYHA-functional class (NYHA-FC), worse forced vital capacity (FVC) (81.2 +/- 20.6% vs 93.6 +/- 20.6%, P < 0.001), worse tricuspid annular plane systolic excursion (TAPSE) (17.4 +/- 5.2 mm vs 19.9 +/- 6.7 mm, P < 0.001), higher incidence of pericardial effusion (30% vs 5.2%, P < 0.001) and similar prevalence of ILD (41.8% vs. 44.9%). In individuals with PAH-SSc, ILD was associated with worse hemodynamics and pulmonary function tests (PFT). Up-front combination therapy was used in 59.8% and 61.7% of patients with and without ILD, respectively. Five-year transplant-free survival rate was 41.1% in PAH-SSc patients and 93.9% in non-PAH-SSc patients (P < 0.001). Global survival of PAH-SSc patients was not affected by ILD regardless its severity. The multivariate survival analysis in PAH-SSc patients confirmed age at diagnosis, worse NYHA-FC, increased PVR, reduced DLCO, and lower management with up-front combination therapy as major risk factors. In conclusion, in PAH-SSc cohort risk of death was greatly increased by clinical, PFT, and hemodynamic factors, whereas it was decreased by up-front combination therapy. Concomitant ILD worsened hemodynamics and PFT in PAH-SSc but not survival regardless of FVC impairment

Risk Factors for COVID-19 in Inflammatory Bowel Disease: A National, ENEIDA-Based Case–Control Study (COVID-19-EII)

(1) Scant information is available concerning the characteristics that may favour the acquisition of COVID-19 in patients with inflammatory bowel disease (IBD). Therefore, the aim of this study was to assess these differences between infected and noninfected patients with IBD. (2) This nationwide case-control study evaluated patients with inflammatory bowel disease with COVID-19 (cases) and without COVID-19 (controls) during the period March-July 2020 included in the ENEIDA of GETECCU. (3) A total of 496 cases and 964 controls from 73 Spanish centres were included. No differences were found in the basal characteristics between cases and controls. Cases had higher comorbidity Charlson scores (24% vs. 19%; p = 0.02) and occupational risk (28% vs. 10.5%; p < 0.0001) more frequently than did controls. Lockdown was the only protective measure against COVID-19 (50% vs. 70%; p < 0.0001). No differences were found in the use of systemic steroids, immunosuppressants or biologics between cases and controls. Cases were more often treated with 5-aminosalicylates (42% vs. 34%; p = 0.003). Having a moderate Charlson score (OR: 2.7; 95%CI: 1.3-5.9), occupational risk (OR: 2.9; 95%CI: 1.8-4.4) and the use of 5-aminosalicylates (OR: 1.7; 95%CI: 1.2-2.5) were factors for COVID-19. The strict lockdown was the only protective factor (OR: 0.1; 95%CI: 0.09-0.2). (4) Comorbidities and occupational exposure are the most relevant factors for COVID-19 in patients with IBD. The risk of COVID-19 seems not to be increased by immunosuppressants or biologics, with a potential effect of 5-aminosalicylates, which should be investigated further and interpreted with caution