Profile of residents: attitude towards tourism in Benalmádena (Costa del Sol, Spain)

Tourism development and evolution along the time causes multiple impacts. Based on characteristic profiles of resident, these impacts may be assessed differently. The attitude of residents and the identification of profiles is a tool that allows to asses the status of destination and propose future strategies for improving the destination. This study aims to analyse the role of residents regarding the perception of tourism.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. Así mismo, Esta investigación ha sido subvencionada por el programa Nacional de Investigación Básica 2012, CS2010-30840. "Geografías de la crisis: analisis urbano turístico de las Islas Baleares, Costa del Sol y principales destinos en el Caribe

Residents´ perceptions of tourism development in Benalmádena (Spain)

DOI: 10.1016/j.tourman.2015.11.007This study examines the residents´ perceptions of the impact of tourism in Benalmádena, and the profiles of the residents according to socio-demographic characteristics. A questionnaire assessed how these characteristics influence the residents' perceptions towards the environment, economy, and socio-cultural aspects. The survey was administered to a stratified sample of 770 residents in Benalmádena. Results show a significant effect of socio-demographic variables on perception of tourism impact. The educational background, place of birth and how long respondents had been living in the community explain a significant amount of the variance in overall attitudes. Interaction analyses revealed that place of birth moderated the relationship between the tourism dimensions and the years of residence. For instance, the respondents with less than five years of residence showed more positive attitude towards the impact of tourism. We offer a profile of these residents according to their perceptions of the impact of tourism in their community.This research has received funding from the Spanish Government, Fundamental Research Program (R+D) (CSO2012-30840), “Geographies of crisis: analysis of urban and tourist territories of the Balearic Islands, Costa del Sol and main tourist destinations of the Caribbean and Central America”. Andalucia Tech, Universidad de Málaga, Spain

Ciencias de la Biología y Agronomía

Este volumen I contiene 17 capítulos arbitrados que se ocupan de estos asuntos en Tópicos Selectos de Ciencias de la Biología y Agronomía, elegidos de entre las contribuciones, reunimos algunos investigadores y estudiantes. Se presenta un Estudio Comparativo de los Recursos Hidrológico-Forestales de la Microcuenca de la Laguna de Epatlan, Pue. (1993 a 2014); la Situación Actual de la Mancha de Asfalto en Maíz (Zea mays L.) en los Municipios de Jiquipilas y Ocozocoautla, Chiapas, México; las poblaciones sobresalientes de maíz de la raza Zapalote Chico, en la Región Istmeña de Oaxaca; Se indica el índice de área foliar de cultivo de Chile Poblano mediante dos métodos en condiciones protegidas; Esquivel, Urzúa y Ramírez exploran el efecto de la biofertilización con Azospirillum en el crecimiento y producción de Jitomate; esbozan su artículo sobre la determinación del nivel de Heterosis en híbridos de Maíz para la Comarca Lagunera; una investigación sobre la estabilización de semilla de Solanum lycopersicum durante el almacenamiento y estimulación de la germinación; acotan sobre el CTAB como una nueva opción para la detección de Huanglongbing en cítricos, plantean su evaluación sobre el aluminio y cómo afecta la vida de florero de Heliconia psittacorum; indican sobre el impacto del H-564C, como un híbrido de maíz con alta calidad de proteina para el trópico húmedo de México; presetan su investigación sobre la producción de Piña Cayena Lisa y MD2 (Ananas comosus L.) en condiciones de Loma Bonita, en Oaxaca; acotan sobre el efecto de coberteras como control biológico por conservación contra áfidos en Nogal Pecanero; esbozan sobre la caracterización de cuatro genotipos de Frijol Negro en Martínez de la Torre, Veracruz, México; presentan una caracterización hidroecológica de la microcuenca de Arroyo Prieto, Yuriría, Gto., y alternativas para su restauración ambiental; presentan su investigación sobre el efecto del hongo Beauveria bassiana sobre solubilización de fosfatos y la disponibilidad de fósforo en el suelo; plantean su investigación sobre la Germinación y regeneración in vitro de Epidendrum falcatum LINDL; esbozan su artículo sobre genotipos de frijol negro y su tolerancia a sequía terminal en Veracruz, México

Research Priorities for Neglected Infectious Diseases in Latin America and the Caribbean Region

Dujardin, J. C. et al. 5 p.-1 tab.Global priorities for research in neglected infectious diseases (NIDs) can be assessed in different ways, but it is important to realize that regional priorities may significantly differ one from another. The region of Latin America and the Caribbean (LAC) is—along with Africa and Asia—more affected by NIDs than other regions of the world. Some of the Latin American NIDs are common to other continents, while others are very specific or disproportionately affect the Latin American region [1– 3] (Table 1). Because of its huge ecological diversity, ongoing environmental changes, and massive migrations, LAC is also a catalyst for the (re-)emergence and spreading of NIDs, both inside and outside the subcontinent. Following a colloquium on NIDs in LAC held in Lima, Peru, between 12 and 14 November 2009, a thematic workshop was organized with the support of the European Commission (EC). It involved 29 scientists (16 from the Americas, two from the Democratic Republic of Congo and India, respectively, and nine from Europe) working on different NIDs and representing several research areas from basic to applied. This report summarizes the consensus comments of the expert group after oral and written consultation. It is envisaged that this document should stimulate a debate within the scientific community and serve as a recommendation for future actions by international or regional funding agencies in the area of NIDs in LACThis work was supported by the Directorate-General for Development Cooperation of the Belgian Government (framework agreement 03, project 95502) and the European CommissionPeer reviewe

Customized Treatment in Non-Small-Cell Lung Cancer Based on EGFR Mutations and BRCA1 mRNA Expression

BACKGROUND: Median survival is 10 months and 2-year survival is 20% in metastatic non-small-cell lung cancer (NSCLC) treated with platinum-based chemotherapy. A small fraction of non-squamous cell lung cancers harbor EGFR mutations, with improved outcome to gefitinib and erlotinib. Experimental evidence suggests that BRCA1 overexpression enhances sensitivity to docetaxel and resistance to cisplatin. RAP80 and Abraxas are interacting proteins that form complexes with BRCA1 and could modulate the effect of BRCA1. In order to further examine the effect of EGFR mutations and BRCA1 mRNA levels on outcome in advanced NSCLC, we performed a prospective non-randomized phase II clinical trial, testing the hypothesis that customized therapy would confer improved outcome over non-customized therapy. In an exploratory analysis, we also examined the effect of RAP80 and Abraxas mRNA levels. METHODOLOGY/PRINCIPAL FINDINGS: We treated 123 metastatic non-squamous cell lung carcinoma patients using a customized approach. RNA and DNA were isolated from microdissected specimens from paraffin-embedded tumor tissue. Patients with EGFR mutations received erlotinib, and those without EGFR mutations received chemotherapy with or without cisplatin based on their BRCA1 mRNA levels: low, cisplatin plus gemcitabine; intermediate, cisplatin plus docetaxel; high, docetaxel alone. An exploratory analysis examined RAP80 and Abraxas expression. Median survival exceeded 28 months for 12 patients with EGFR mutations, and was 11 months for 38 patients with low BRCA1, 9 months for 40 patients with intermediate BRCA1, and 11 months for 33 patients with high BRCA1. Two-year survival was 73.3%, 41.2%, 15.6% and 0%, respectively. Median survival was influenced by RAP80 expression in the three BRCA1 groups. For example, for patients with both low BRCA1 and low RAP80, median survival exceeded 26 months. RAP80 was a significant factor for survival in patients treated according to BRCA1 levels (hazard ratio, 1.3 [95% CI, 1-1.7]; P = 0.05). CONCLUSIONS/SIGNIFICANCE: Chemotherapy customized according to BRCA1 expression levels is associated with excellent median and 2-year survival for some subsets of NSCLC patients , and RAP80 could play a crucial modulating effect on this model of customized chemotherapy. TRIAL REGISTRATION: (ClinicalTrials.gov) NCT00883480

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

The original version of this article unfortunately contained a mistake

Proyecto de inversión para la creación de una planta productora de chocolate de exportacion

SE ESTABLECE UNA PLANTA PRODUCTORA DE CHOCOLATE DE EXPORTACION, QUE CUMPLA CON ESTANDARES Y CALIDAD PARA QUE DE ESTA FORMA PUEDA COMPETIR EN EL MERCADO INTER, EN ESTE PROYECTO SE ENFOCA LA ELBORACION DEL CHOCOLATE FINO PERO SE TOMA COMO REFERENCIA LA OFERTA Y LA DEMANDA DEL PRODUCTO EN GENERAL, YA QUE COMUNMENTE ES LO QUE SE CONSUME EN EL MERCADO. SE DEMUESTRA QUE EXISTE UNA FUENTE DE INVERSION EN ESTE RUBRO, Y A PESAR DE SER UAN INVERSION SUMAMENTE FUERTE, SE PROBARA QUE TAN RENTABLE ES LA CREACION DE ESTA PLANTA PRODUCTORA, SU COSTO DE PRODUCCION, INGRESOS, EGRESOS Y UTILIDAD

Torremolinos, análisis de cambios urbanos hoteleros en un destino de sol y playa

Presentación de la comunicación del congreso.The city of Torremolinos was one of the pioneering spaces in the implementation of mass tourism of sun and beach on the Costa del Sol, Spain. The town of Torremolinos in 2014 had a population of 67,353 inhabitants, an area of 19.8 km2. The city is located in the province of Malaga in the Costa del Sol. The objectives of this study are approaching the study of the implementation of the hotels in Torremolinos and its integration into the urban system of the municipality. The changes in land use are analyzed during the fifty years of the study. We aim to characterize the urban-regional model generated by the hotel implantation as singular element Torremolinos growth Method To achieve these objectives has produced a digital mapping of urban growth in Torremolinos (ArcGis.10). We have conducted a mapping of the evolution of urban areas and the location of the hotel industry, from aerial orthophotos. Regarding the layer hotels, we have made the digitization of occupied facilities and buildings of the hotel area. To do this operation, we have used the Register of Hoteliers of the Junta de Andalucía (Regional Government) and we have located hotels with the help of Google Maps and StreetView. We have conducted a cluster analysis about the hotel supply of Torremolinos. Results and conclusions Between 1957 and 1977, was built most of the tourist area of Torremolinos, especially hotels and apartments. In these twenty years urbanization rate was 36.1 ha / year, which was reflected: (i) intense growth of dense urban area (it has tripled from 75.9 to 242.4 ha.. ); (ii) expansion of housing developments that quintupled its surface and above all, (iii) strong increase in other developed areas (5,598.2%), linked to infrastructure. The rate of urbanization and construction was more moderate in the following periods. In the analysis period (1959-2010) we observed that the average plot of hotels has increased: from 10,000 m2 to 20,000 m2. This increase was a business strategy to maintain low profit margin of hotels for mass tourism. Cluster analysis identified two main hotel groups: the seaside front cluster and backside group. This study shows the evolution of a mature destination for sun and beach, which has maintained over time its hotel activity.Universidad de Málaga. Campus de Excelencia Internacional Andalucía TECH