68 research outputs found

    Umowa o podział majątku wspólnego a zajęcie prawa do podziału tego majątku (art. 912 Kodeksu postępowania cywilnego). Glosa do postanowienia Sądu Najwyższego z dnia 14 lipca 2017 r. (II CSK 718/16, OSNC 2018, nr 7–8, poz. 78)

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    The commentary is approving. A proceeding concerning the distribution of joint marital property was ongoing in the case. It was issued upon the request of the creditor, who in the course of the enforcement proceedings made a request to have the right to have a distribution claim of that joint marital property. After making this request, the spouses conducted the distribution of their property on the grounds of a contract. In the decision of 14 July 2017, the Supreme Court settled the issue whether a distribution of joint marital property agreement, made during the course of the enforcement proceedings, is void against the enforcement creditor. The Supreme Court has given a positive reply to this question. The commentary concerns the interpretation of Article 912 of the Code of Civil Procedure, which apart from short comments, has never been analysed in the context of the doctrine. At the same time, the comments contain short observations repeated by most authors. In this regard, the issues raised in the commentary are the first scholarly publication deepening this topic. The issues connected with making the request to have the right to have a claim to distribute joint marital property, time as of which this request comes into effect and the consequences of the request, especially with respect to the enforcement creditor, are discussed in the commentary to this decision.Glosa ma charakter aprobujący. W sprawie toczyło się postępowanie o podział majątku wspólnego małżonków. Zostało ono wszczęte na wniosek wierzyciela, który w toku postępowania egzekucyjnego dokonał zajęcia prawa do żądania podziału tego majątku. Po dokonaniu tego zajęcia małżonkowie dokonali podziału majątku w drodze umowy o podział majątku wspólnego. W postanowieniu z dnia 14 lipca 2017 r. Sąd Najwyższy rozstrzygnął kwestię, czy umowa o podział majątku wspólnego, zawarta w toku postępowania egzekucyjnego, jest bezskuteczna wobec wierzyciela egzekwującego. Sąd Najwyższy udzielił pozytywnej odpowiedzi na to pytanie. Glosa dotyczy wykładni art. 912 Kodeksu postępowania cywilnego, który poza krótkimi wypowiedziami komentarzowymi, nigdy nie został dokładnie przeanalizowany w doktrynie, a komentarze zawierają krótkie, powielane przez autorów uwagi. W tym zakresie problematyka poruszona w glosie stanowi pierwsze w tym zakresie pogłębione opracowanie naukowe. W glosie omówiono zagadnienia związane z zajęciem prawa do żądania podziału majątku wspólnego, chwilę, z jaką następuje to zajecie, a także skutki zajęcia, w szczególności w stosunku do wierzyciela egzekwującego

    'Laboratory investigations of diclofenac migration in saturated porous media - a case study

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    At present, concentrations of pharmaceuticals in surface and ground waters are low; however, even low concentrations of certain substances may prove very harmful. One of such pharmaceutical drugs is diclofenac, a popular non-steroidal anti-inflammatory drug (NSAID). For this reason, it is important to determine its mobility in groundwater and to estimate parameters of migration. Authors conducted column tests for two porous media: an artificial one, consisting of glass granules, and a natural one, i.e., sandur sand obtained from a site north of the city of Poznań (Poland). During the test, impulse breakthrough curves of chloride ions and diclofenac were recorded. The results were used to identify a specific sorption model and to determine values of migration parameters. Solutions of the inverse problem using optimisation methods and of equations of mathematical migration models were carried out in a MATLAB environment. Based on test results, the mobility of diclofenac is shown to be very high and comparable to that of chloride ions. The tests also revealed a slight and irreversible sorption of diclofenac on grains of both porous media

    The verification of the estimation of transport and sorption parameters in the MATLAB environment. A column test

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    Mathematical modelling of the migration of pollutants in the groundwater environment requires knowledge of the values of transport and sorption parameters. The aim of this study was 1) to determine the values of advection, dispersion and sorption parameters of selected tracers that are transported through a porous medium, and 2) to verify the applied parameters estimation procedure.The authors examined the migration of a solution containing conservative and reactive tracers (chloride, nitrate, lithium and ammonium ions) through a sample of medium sand. The soil sample for the column test was taken from an aquifer near the Tursko groundwater intake (Wielkopolska province, Poland).The parameter estimation procedure, conducted in the MATLAB environment, included the numerical solution of the differential equations of transport and sorption, and the application of the numerical optimization method. During the identification, the authors tested twelve mathematical models including the advection-dispersion model, as well as single and hybrid (i.e. two-site) sorption models. The authors made a comparison of parameter values obtained by means of the global and local optimization method. The fitting quality was assessed by calculatingthe root mean square error RMSE and correlation coefficient r. As a result of the research, the authors determined the values of the advection-dispersion parameters: hydraulic conductivity k, effective porosity ne, and longitudinal dispersivity α. The authors found out that the nature of lithium ions migration is best captured by the single sorption model (equilibrium sorption), whereas the nature of ammonium ions migration is by the hybrid model with irreversible sorption. Lithium ions on the tested soil revealed low sorption intensity, ammonium ions showed medium intensity, while nitrate ions were transported at the same rate as chloride ions, exhibiting no retardation. The verification of parameter estimation in the MATLAB environment was carried out by comparing itagainst the alternative, well-known and often tested method, based on analytical solutions of the transport and sorption equation, combined with optimization within the FIELD and KLUTE-STEP programmes

    Synthesis of new 4-butyl-arylpiperazine-3-(1H-indol-3-yl)pyrrolidine-2,5-dione derivatives and evaluation for their 5-HT1A_{1A} and D2_{2} receptor affinity and serotonin transporter inhibition

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    A series of novel 4-butyl-arylpiperazine-3-(1H-indol-3-yl)pyrrolidine-2,5-dione derivatives were synthesized and evaluated for their 5-HT1A_{1A}/D2 receptor affinity and serotonin reuptake inhibition. The compounds exhibited high affinity for the 5-HT1A_{1A} receptor, (especially 4d Ki_{i} = 0.4 nM) which depended on the substitution pattern at the phenylpiperazine moiety. From this series screen, compound 4c emerged with promising mixed receptor profiles for the 5-HT1A_{1A}/D2 receptors and the serotonin transporter (Ki_{i} = 1.3 nM, 182 nM and 64 nM, respectively).long-chain arylpiperazinesdepression5-HT1A_{1A} receptor ligandsschizophreniamulti-target ligand

    Seasonal changes in chemical and mineralogical composition of sewage sludge incineration residues and their potential for metallic elements and valuable components recovery

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    The incineration products composition is dependent on the incineration technology, operating conditions and also on the waste feed composition, which can change seasonally, depending on the temporal growth of the population due to tourism, micro-industry seasonality, intensity of atmospheric precipitation and other factors. Seasonal variations in potentially valuable elements concentrations in incineration products are visible but their overall content is low, therefore this material should not be considered as a source of valuable elements. Due to high content of phosphorus (7.5 wt%) only the fly ash can be considered as a potential source of this critical raw material

    Solanum nigrum extract and solasonine affected hemolymph metabolites and ultrastructure of the fat body and the midgut in Galleria mellonella

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    Glycoalkaloids, secondary metabolites abundant in plants belonging to the Solanaceae family, may affect the physiology of insect pests. This paper presents original results dealing with the influence of a crude extract obtained from Solanum nigrum unripe berries and its main constituent solasonine on the physiology of Galleria mellonella (Lepidoptera). Both extract and solasonine applied in the nourishment changed the level of hemolymph metabolites such as sugars, polyols and proline, and ultrastructure of the fat body and the midgut cells. The extract and solasonine, tested in the same concentration found in the extract, decreased the proline level, while mannitol was under the limit of detection in the hemolymph. The extract increased the erythritol level in the hemolymph compared to control, enlarged the intracellular space in fat body cells, decreased cytoplasm and lipid droplets electron density. In the midgut, vacuolized areas of cytoplasm ap-peared with vast reticulum systems. Solasonine, tested with three concentrations, caused the decrease of cytoplasm electron density in both fat body and midgut cells. Obtained results high-lighted the disturbance of the midgut and the fat body due to glycoalkaloids and the potential role of hemolymph ingredients in its detoxification

    Apophis planetary defense campaign

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    We describe results of a planetary defense exercise conducted during the close approach to Earth by the near-Earth asteroid (99942) Apophis during 2020 December–2021 March. The planetary defense community has been conducting observational campaigns since 2017 to test the operational readiness of the global planetary defense capabilities. These community-led global exercises were carried out with the support of NASA's Planetary Defense Coordination Office and the International Asteroid Warning Network. The Apophis campaign is the third in our series of planetary defense exercises. The goal of this campaign was to recover, track, and characterize Apophis as a potential impactor to exercise the planetary defense system including observations, hypothetical risk assessment and risk prediction, and hazard communication. Based on the campaign results, we present lessons learned about our ability to observe and model a potential impactor. Data products derived from astrometric observations were available for inclusion in our risk assessment model almost immediately, allowing real-time updates to the impact probability calculation and possible impact locations. An early NEOWISE diameter measurement provided a significant improvement in the uncertainty on the range of hypothetical impact outcomes. The availability of different characterization methods such as photometry, spectroscopy, and radar provided robustness to our ability to assess the potential impact risk

    The thiosemicarbazone Me2NNMe2 induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition

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    Due to their high biological activity, thiosemicarbazones have been developed for treatment of diverse diseases, including cancer, resulting in multiple clinical trials especially of the lead compound Triapine. During the last years, a novel subclass of anticancer thiosemicarbazones has attracted substantial interest based on their enhanced cytotoxic activity. Increasing evidence suggests that the double-dimethylated Triapine derivative Me2NNMe2 differs from Triapine not only in its efficacy but also in its mode of action. Here we show that Me2NNMe2- (but not Triapine)-treated cancer cells exhibit all hallmarks of paraptotic cell death including, besides the appearance of endoplasmic reticulum (ER)-derived vesicles, also mitochondrial swelling and caspase-independent cell death via the MAPK signaling pathway. Subsequently, we uncover that the copper complex of Me2NNMe2 (a supposed intracellular metabolite) inhibits the ER-resident protein disulfide isomerase, resulting in a specific form of ER stress based on disruption of the Ca2+ and ER thiol redox homeostasis. Our findings indicate that compounds like Me2NNMe2 are of interest especially for the treatment of apoptosis-resistant cancer and provide new insights into mechanisms underlying drug-induced paraptosis. © 2018, The Author(s)
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