213 research outputs found
Propuesta de planificación estratégica para la mejora y renovación de la imagen corporativa del Instituto Superior Tecnológico Particular Sudamericano de la ciudad de Cuenca
Hoy en día la sociedad reclama honestidad y transparencia al mundo empresarial, por tanto, las empresas se ven en la necesidad de buscar estrategias que permitan persuadir a los públicos a través de una imagen positiva que provoque en ellos el sentimiento de confianza, satisfacción y fidelidad. Es así como se planteó dicho proyectotitulado Propuesta de planificación estratégica para la mejora y renovación de la imagen corporativa del Instituto Superior Tecnológico Particular Sudamericano de la ciudad de Cuenca, que tiene como objetivo, elevar el nivel de calidad de imagen corporativa de la institución, pero enfocada en el ámbito de las relaciones públicas; esto consiste en valorar todos los activos intangibles del instituto, mismos que se relacionan con: la cultura corporativa, la filosofía corporativa, y la comunicación organizacional.
Para ello y para mayor discernimiento del tema, se explicará el proyecto en cuatro capítulos: el primero hace referencia a la fundamentación teórica, basada en teorías de diferentes autores de la rama de comunicación y relaciones públicas; el segundo capítulo se centra en el análisis general del Instituto, esto comprende un análisis interno y externo, la investigación metodológica y el análisis FODA; el tercer capítulo presenta la propuesta de un plan de mejora para la imagen corporativa del Instituto Tecnológico Particular Sudamericano; y finalmente, en el cuarto capítulo se expone la aplicación y ejecución de las estrategias planteadas en el proyecto.Nowadays society demands honesty and transparency to business world, therefore, enterprises are in need to seek strategies to persuade people with a positive image that causes them the feeling of confidence, satisfaction and loyalty . Thus, the project entitled Proposal of strategic planning for the improvement and renewal of the corporate image ofInstitutoTecnológico Particular Sudamericano in Cuenca, has the objective of raising the quality level of corporate image of the institution, but focusing on the field of public relations; this is to value all intangible assets of the institute, which are related to: corporate culture, corporate philosophy, and organizational communication.
For this and for further insight into the topic, the project will be explained in four chapters: the first one refers to the theoretical basis based on the theories of different authors in the field of social communication and public relations; the second chapter focuses on the general analysis of the institute, this comprises an internal and external analysis and methodological research and SWOT analysis; in the third chapter, a proposal for an improvement plan for the corporate image of InstitutoTecnológico Particular Sudamericano is presented; and finally, in the fourth chapter, the application and execution of the strategies proposed in the project are exposed.Licenciada en Ciencias de la Comunicación Social. Mención Publicidad y Relaciones PúblicasCuenc
La responsabilidad social corporativa como oportunidad para las empresas turísticas
[Resumo] En primeiro lugar realízase unha aproximación xeral ao concepto de responsabilidade social
empresarial e coméntanse algunhas das características deste novo modelo de xestión. A
seguir, repásanse algunhas das responsabilidades que cabe esperar que as empresas turísticas
asuman, así como tamén algunhas iniciativas de dentro e fóra do sector do turismo para
fomentar a RSC por parte de distintos organismos internacionais, e as iniciativas desenvolvidas
polas propias empresas neste sentido. Nas últimas seccións estúdase unha iniciativa concreta,
a norma SA8000 de auditoría social, e as memorias de sustentabilidade.[Resumen] Primero se hace una aproximación general a la responsabilidad social empresarial
y se comentan algunas características de este nuevo modelo de gestión. Después se hace un
repaso de algunas de las responsabilidades que cabe esperar que desarrollen las empresas
turísticas, así como algunas iniciativas, dentro y fuera del sector del turismo, para fomentar la
responsabilidad por parte de distintos organismos internacionales, y las iniciativas desarrolla-
das por las propias empresas. En los últimos apartados se estudia una iniciativa concreta, la
norma SA8000 de auditoría social, y las memorias de sostenibilidad.[Abstract] This study begins with a general overview of corporate social responsibility, commenting on
some of the characteristics of this new management model. The study then reviews some of
the responsibilities that tourism companies can be expected to perform, as well as some ini-
tiatives, both inside and outside the tourism sector, to promote responsibility by different
international bodies, and the initiatives performed by the companies themselves. The final sec-
tions study a specific initiative, standard SA8000 on social accountability, and sustainability
reports
Enfoque perioperatorio de la insuficiencia suprarrenal en el contexto de un paciente con síndrome poliglandular: Reporte de caso
Fast Quality Control of Natural Gas for Commercial Supply and Transport Utilities
Financiado para publicación en acceso aberto: Universidade da Coruña/CISUG[Abstract] Quality control of natural gas frequently relies on off-line slow standardized chromatographic techniques. Previous implementations of new measurement approaches focused of synthetic mixtures without extensive industrial validation. Here, a fast alternative based on infrared spectra is presented to predict the gas constituents and a physical parameter, the Wobbe index. Commercial samples instead of synthetic mixtures were used to develop predictive models. Method performance parameters were calculated and ca. 100 % of the sample-specific confidence intervals for the predictions overlapped with those of the reference values and the approach was unbiased and precise. The limits of detection and quantification (classical and considering errors of type I and II) outperformed other approaches. Validation included commercial samples and primary mixtures. Furthermore, prediction models considering reduced sets of variables were sought for using Markov-chain Monte Carlo guided searches (uninformative variable elimination and random frog) and common (iPLS, UVE and SR) approaches. The prediction errors and limits of detection of these ‘reduced’ models outperformed those from other approaches. The methodology takes only minutes to analyse a sample, requires few sample and no reagents (only some argon), making this approach cost-effective and environmentally-friendly.Xunta de Galicia; ED431C-2017/2
Resultados contrapuestos en una experiencia piloto de docencia inversa
El uso de la tecnología de la información y las comunicaciones permite explorar nuevas alternativas para la mejora del proceso de enseñanza-aprendizaje. En esta comunicación se exponen los resultados obtenidos en relación con la docencia de la materia de Teoría de Autómatas durante el segundo año de la experiencia piloto de implantación de la docencia inversa en el Grado de Informática de la Universidad Politécnica de Valencia. Los buenos resultados obtenidos por el equipo en el primer año sugirieron mantener el protocolo de trabajo y autoevaluación previa a la clase presencial. La experiencia limitada del primer año se mantuvo en un grupo exclusivo de matrícula voluntaria, extendiéndose además de forma puntual en la docencia de distintos grupos de matrícula ordinaria para valorar el efecto en grupos de mayor tamaño. Los resultados obtenidos en el segundo año no son comparables a los obtenidos el curso anterior, siendo necesaria una modificación del protocolo si se busca utilizar la docencia inversa en grupos de tamaño medio/alto
Evaluation of diagnostic and prognostic candidate biomarkers in drug-induced liver injury vs. other forms of acute liver damage
Aims
Detection and characterization of idiosyncratic drug-induced liver injury (DILI) currently rely on standard liver tests, which are suboptimal in terms of specificity, sensitivity and prognosis. Therefore, DILI diagnosis can be delayed, with important consequences for the patient. In this study, we aimed to evaluate the potential of osteopontin, cytokeratin-18 (caspase-cleaved: ccK18 and total: K18), α-glutathione-S-transferase and microRNA-122 as new DILI biomarkers.
Methods
Serial blood samples were collected from 32 DILI and 34 non-DILI acute liver injury (ALI) cases and a single sample from 43 population controls without liver injury (HLC) and analysed using enzyme-linked immunosorbent assay (ELISA) or single-molecule arrays.
Results
All biomarkers differentiated DILI and ALI from HLC with an area under receiver operator characteristic curve (AUC) value of >0.75 but were less efficient in distinguishing DILI from ALI, with ccK18 (0.79) and K18 (0.76) demonstrating highest potential. However, the AUC improved considerably (0.98) for ccK18 when comparing DILI and a subgroup of autoimmune hepatitis cases. Cytokeratin-18, microRNA-122 and α-glutathione-S-transferase correlated well with traditional transaminases, while osteopontin correlated most strongly with the international normalized ratio (INR).
Conclusions
ccK18 appears promising in distinguishing DILI from autoimmune hepatitis but less so from other forms of acute liver injury. Osteopontin demonstrates prognostic potential with higher levels detected in more severe cases regardless of aetiology.Consejería de Salud y Familia de la Junta de
Andalucía, Grant/Award Numbers: PI 0274-2016, P18-RT-3364; Instituto de Salud Carlos III (ISCIII) cofounded by Fondo Europeo de Desarrollo Regional - FEDER, Grant/Award Numbers: PI19/00883, PI18/00901,
UMA18-FEDERJA-193; Universidad de Málaga/CBUA for open access charge: Universidad de Málaga / CBUA.
Funding for open access charge: Universidad de Málaga / CBU
Modeling the natural gas knocking behaviour using gas-phase infrared spectra and multivariate calibration
[Abstract] To assess the knocking properties of natural gas (NG) when it is used as fuel for vehicles is vital to optimize the design and functioning of their motors. Analytical efforts in this field are needed as the engines used to define it empirically are not available anymore, and existent mathematical algorithms yield different accuracy. The hybridization of gas-phase infrared spectrometry and partial least squares multivariate regression is presented first time to address the determination of the methane number (MN) of NG samples. It circumvents the need for the previous knowledge of the NG composition required to apply dedicated equations. The use of true NG samples to develop the models is also quite new in the field. Proof-of-concept studies were made with synthetic spectra and, then, a collection of liquefied NG samples for which MN values were computed by the National Physics Laboratory algorithm (NPL) from their sample composition were used to develop operative models. Additional validation was made with a collection of synthetic standard mixtures prepared for two European projects (EMRP LNG II and EMPIR LNG III) whose service methane numbers (SMN) were measured with an engine. The FTIR-PLS approach yielded statistically unbiased predictions with average standard errors around 0.4% MN when compared to the NPL-MN and SMN values, and standard deviations of the means ca. 1% MN. The approach is fast, cost effective as it involves standard instrumentation, and can be considered compliant with the green chemistry principles.This work is part of the EMPIR 16ENG09 project ‘Metrological support for LNG and LBG as transport fuel (LNG III)’. This project has received funding from the EMPIR programme co-financed by the Participant States and from the European Union's Horizon 2020 Research and Innovation programme. The authors from TU Braunschweig would like to thank IAV, Mahle, MAN Truck & Bus and Motortech for their support in preparing the test engine. The Group of Applied Analytical Chemistry of the University of A Coruña acknowledges Mestrelab, Reganosa and Naturgy for hiring its services for FTIR method developmentFinanciado para publicación en acceso aberto: Universidade da Coruña/CISU
New insights in the TRAZELGA project for the adult type 1 Gaucher disease patients treated with eliglustat follow-up
Reviewing Self-Injuries Behavior in Macaques: The Role of Early Experience and Genetics in an Integrated Non-Human Model
Genetic differences in non-human primates and the context where they were reared are important in the determination
of their behaviors. Some studies suggest that Self-Injurious Behavior results from stress or anxiety, but
some macaques appear to be more vulnerable to acquiring Self-Injurious Behavior. Vulnerability and risk for
socially reared macaques of developing Self-Injurious Behavior increased when they experienced early adverse
events and suffered from consequent stress. Stressful events can cause alterations in the neuroendocrine and
neuropeptide systems associated with the regulation of stress and anxiety. Dysregulation in these systems contributes
to the occurrence of anxious episodes that lead to self-harm. This could be used by those animals to
counteract the effects of anxiety, causing euphoria by releasing endogenous opioids. In developing an integrative
approach of Self-Injurious Behavior, we propose the diathesis-stress model to illustrate how the environment
and genetics are influenced as well, taking rhesus monkeys as an example. Rhesus macaques and humans have
essentially the same gene 5-HTT as well as functional polymorphism. The allelic variation in the region promoting
the serotonin transporter gene (5-HTT) was associated with significant differences in the number of depressive
symptoms and contributions to social reward and punishment. Growing up without the mother and the
rearing environment are important risk factors for developing abnormal behaviors. The main idea is that monkeys
who carry short 5-HTT allele and are reared with their peers (without their mother) suffer from neurobiological
developmental delay, deteriorated serotonergic functioning and act more aggressively. Monkeys who
carry short 5-HIAA allele and are reared with their mothers, though, show normal behavioral patterns. We
could conclude that carrying the short allele of gene 5-HTT leads to a psychopathological tendency in macaques
with a poor parenting history, but it may be adaptive for those who establish an attached relationship with their
mothers. Stressful early experiences result in impaired 5-HTT expression as well. There are both specific genetic
and environmental factors which pose a risk in the development of adverse responses to stress and environment.
Rhesus macaques, as well as humans, show big individual differences in their responses to environmental stress.
Some are very fearful and anxious, others are aggressive and impulsive. It is possible to identify genetic and environmental
patterns that contribute to these differe
- …