DCMF: DC & Microformats, a good marriage

This report introduces the Dublin Core Microformats (DCMF) project, a new way to use the DC element set within X/HTML. The DC microformats encode explicit semantic expressions in an X/HTML webpage, by using a specific list of terms for values of the attributes “rev” and “rel” for and elements, and “class” and “id” of other elements. Microformats can be easily processed by user agents and software, enabling a high level of interoperability. These characteristics are crucial for the growing number of social applications allowing users to participate in the Web 2.0 environment as information creators and consumers. This report reviews the origins of microformats; illustrates the coding of DC microformats using the Dublin Core Metadata Gen tool, and a Firefox extension for extraction and visualization; and discusses the benefits of creating Web services utilizing DC microformats

Growth and yield models in Spain: historical overview, contemporary examples and perspectives

Producción CientíficaIn this paper we present a review of forest models developed in Spain in recent years for both timber and non timber production and forest dynamics (regeneration, mortality,..). Models developed are whole stand, size (diameter) class and individual-tree. The models developed to date have been developed using data from permanent plots, experimental sites and the National Forest Inventory. In this paper we show the different sub-models developed so far and the friendly use software. Main perspectives of forest modelling in Spain are presented

Personal factors, living environments, and specialized supports: their role in the self-determination of people with intellectual disability

The self-determination of people with disabilities, and specifically people with intellectual disabilities (ID), is a growing issue due to its relevance in the field of inclusion and human rights. Although research has shown a significant relationship between self-determination and intelligence, other factors also contribute to its development. The purpose of this study was to understand what other variables may be influencing self-determination. Using the scores from 483 adolescents and adults with ID who completed the AUTODDIS scale, we performed inferential and regression analyses to determine the relationships between levels of self-determination, personal variables (sex, age, severity of ID), and contextual variables (living environment, specialized supports). We found that self-determination is affected by the severity of ID, and when this variable is controlled for, greater self-determination is mainly related to receiving occupational support and support for autonomy and independent living. Results also showed that, together with ID severity, occupational and psychoeducational support, as well as support for autonomy and independent living, were also predictors of the level of self-determination. In conclusion, this study confirms the importance of contextual variables in the development of self-determination in people with ID, placing the focus of intervention on social opportunities

Age-Mediated Transcriptomic Changes in Adult Mouse Substantia Nigra

Substantia nigra pars compacta (SNpc) is highly sensitive to normal aging and selectively degenerates in Parkinson's disease (PD). Until now, molecular mechanisms behind SNpc aging have not been fully investigated using high throughput techniques. Here, we show early signs of aging in SNpc, which are more evident than in ventral tegmental area (VTA), a region adjacent to SNpc but less affected in PD. Aging-associated early changes in transcriptome were investigated comparing late middle-aged (18 months old) to young (2 months old) mice in both SNpc and VTA. A meta-analysis of published microarray studies allowed us to generate a common >transcriptional signature> of the aged (≥ 24 months old) mouse brain. SNpc of late-middle aged mice shared characteristics with the transcriptional signature, suggesting an accelerated aging in SNpc. Age-dependent changes in gene expression specific to SNpc were also observed, which were related to neuronal functions and inflammation. Future studies could greatly help determine the contribution of these changes to SNpc aging. These data help understand the processes underlying SNpc aging and their potential contribution to age-related disorders like PD. © 2013 Gao et al.This work was funded by Spanish Ministry of Science and Education, Andalusian Government, and “Marcelino Botín” Foundation. “CIBERNED” (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) was funded by the Spanish “Carlos III” Institute of Health. LME was supported by the Spanish “Carlos III” Institute of Health. Support from the Spanish Ministry of Science and Education for MHF (“FPI” predoctoral fellowship) is also acknowledged.Peer Reviewe

Therapeutic communication does not burn you out; it is invigorating

El objetivo de este trabajo es ayudar a clarificar y modificar la idea que tienen ciertos profesionales de que la "relación de ayuda quema". Es decir, tratar de precisar, partiendo de cómo la Relación de Ayuda si la entendemos en su justo valor, no sólo no quema, no nos lleva al síndrome del burn-out, sino que ésta es vivificante tanto a nivel personal como profesional. Si ciertos profesionales han llegado a esa triste experiencia, (de que la relación de ayuda quema) pensamos se debe, entre otras razones: por una parte, a no tener una idea clara de lo que es la comunicación y la relación terapéutica o de ayuda; por otra parte, a habernos olvidado que no podemos dedicarnos a esta noble labor, sin antes haber trabajado un mínimo sobre nosotros mismos, es decir, sobre nuestro crecimiento personal, autoestima, problemas, conflictos, etc. Si esto no se hace, cabe el peligro de no saber dónde nos situamos, transgrediendo ciertos principios o límites que van anejos a la Relación de Ayuda. Asi mismo, intentamos exponer algunas de las fases por las que se llega al síndrome del burn-out, con el fin de que nos sirvan de reflexión, y poder así restaurar la "vida" personal y profesional que hayamos podido haber dejado en este caminar acompañando a los pacientes.The aim of this work is to help to clarify and modify the perception of some professionals that therapeutic communication is something that leads to "burn out". That is to say, to show how therapeutic communication not only does not burn you out, but can be invigorating at both a personal and professional level. The fact that some professionals have been through this sad experience (burnt out by therapeutic communication) may be due, among other reasons, to not having a clear concept of communication and the therapeutic relationship, and having forgotten that we cannot dedicate ourselves to this noble task without working first on ourselves, our personal growth, self-esteem, problems, conflicts, etc. If this is not done, there is a risk of not knowing where we stand—transgressing certain limits or principles that go along with therapeutic communication. Moreover, we try to state some of the stages of "burn-out syndrome", in order to help us to reflect, and to restore the professional and personal "life" that we may have left behind while caring for our patients

Vaccination of rabbits with immunodominant antigens from Sarcoptes scabiei induced high levels of humoral responses and pro-inflammatory cytokines but confers limited protection

© 2016 The Author(s). Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.[EN]Background: Vaccination is an attractive ecological alternative to the use of acaricides for parasite control. However, effective anti-parasite vaccines against sarcoptic mange have not yet been developed. The purpose of this study was first to identify Sarcoptes scabiei immunodominant antigens and second to evaluate them as vaccine candidates in a rabbit/S. scabiei var. cuniculi model. Methods: The S. scabiei Ssλ15 immunodominant antigen was selected by immunoscreening of a S. scabiei var. hominis cDNA. The full-length cDNA was sequenced and cloned into the pGEX vector and the recombinant protein expressed in BL21 (DE3) cells and purified. A vaccination trial was performed consisting of a test group (n = 8) immunised with recAgs (a mix of two recombinant antigens, Ssλ15 and the previously described Ssλ20ΔB3) and a control group (n = 8) immunised with PBS. All analyses were performed with R Statistical Environment with α set at 0.050. Results: The full-length open reading frame of the 1,821 nt cloned cDNA encodes a 64 kDa polypeptide, the sequence of which had 96 % identity with a hypothetical protein of S. scabiei. Ssλ15 was localised by immunostaining of skin sections in the tegument surrounding the mouthparts and the coxa in the legs of mites. Rabbit immunisation with recAgs induced high levels of specific IgG (P < 0.010) and increased levels of total IgEs. However, no significant clinical protection against S. scabiei challenge was detected. Unexpectedly, the group immunised with the recAgs mix had significantly higher lesion scores (P = 0.050) although lower mean mite densities than those observed in the control group. These results might indicate that the lesions in the recAgs group were due not only to the mites density but also to an exacerbated immunological response after challenge, which is in agreement with the specific high levels of pro-inflammatory cytokines (IL-1 and TNFα) detected after challenge in this group. Conclusions: The selected antigens delivered as recombinant proteins had no clinical protective efficacy against S. scabiei infestation although immunisation reduced mite density. However, these results pave the way for future studies on alternative production systems, adjuvants, delivery methods and combinations of antigens in order to manage stimulation of clinical protective immune responses.SIThis work was partially funded by grant RTA11-00087-00-00 from the Spanish Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Fondo Europeo de Desarrollo Regional (FEDER), AGL2010-22200-C02-01 from Spanish Ministry (MINECO) and the Biotechnology and Biological Sciences Research Council (BBSRC) grant BBS/E/I/00002014

Las gotas lípidicas nucleares constituyen un nuevo dominio nuclear

Teniendo en cuenta que los lípidos neutros nucleares pueden representar pooles alternativos de ácidos grasos y lípidos de señalización celular, el objetivo de este trabajo fue dilucidar un modelo de organización de estos lípidos neutro

Aceites esenciales: productos antimicrobianos y antioxidantes naturales en la industria agroalimentaria

[ES] Los consumidores son conscientes del peligro derivado del uso de antioxidantes y antimicrobianos sintéticos en la industria agroalimentaria, demandando alternativas más seguras y ecológicas. En este estudio, se ha determinado la actividad antioxidante de aceites esenciales comerciales mediante el método DPPH y su efecto antimicrobiano frente a la bacteria Pseudomonas syringae y el hongo fitopatógeno Fusarium oxysporum a través del empleo del método estandarizado de disco. Los aceites esenciales de clavo, ajedrea, canela y orégano, así como carvacrol, mostraron la máxima actividad antioxidante, comparable a antioxidantes establecidos. El aceite esencial de gaulteria fue el más potente inhibidor del crecimiento de P. syringae en las dosis más altas (20 y 10 µL) ensayadas. El aceite esencial de orégano, así como su componente principal carvacrol, detuvieron el crecimiento de la bacteria incluso a la dosis más baja ensayada (1 µL). Los aceites esenciales de canela, orégano y menta inhibieron el desarrollo de F. oxysporum en todas las dosis (20, 10 y 5 µL) aplicadas. En general, la mayoría de aceites esenciales mostraron más actividad antifúngica que antibacteriana y antioxidante.[EN] Consumers are aware of the dangers arising from the use of synthetic antioxidants and antimicrobials in the agrifood industry, demanding safer and "greener" alternatives. In this study, the antioxidant activity of commercial essential oils through DPPH method, their antimicrobial effects against the bacterium Pseudomonas syringae and the phytopathogenic fungus Fusarium oxysporum by means of the standardized disk method were determined. Clove along with winter savory, cinnamon and oregano essential oils as well as carvacrol showed the highest antioxidant activity comparable to reference standards. Wintergreen essential oil was the most potent inhibitor against P. syringae growth at the highest doses (20 and 10 µL). Oregano essential oil and its main component carvacrol were able to stop the bacterium growth even at the lowest treatment (1 µL). Cinnamon, oregano and peppermint essential oils inhibited F. oxysporum development at all doses (20, 10 and 5 µL) assayed. In general, most of the essential oils displayed more antifungal than antibacterial and antioxidant activities.Ibáñez, MD.; López-Gresa, MP.; Lisón, P.; Rodrigo Bravo, I.; Belles Albert, JM.; González-Mas, MC.; Blázquez, MA. (2020). Essential oils as natural antimicrobial and antioxidant products in the Agrifood Industry. Nereis. Revista Iberoamericana Interdisciplinar de Métodos, Modelización y Simulación. (12):55-69. https://doi.org/10.46583/nereis_2020.12.585S55691

Analizadores de red de bajo coste

El uso masivo de dispositivos electrónicos, tanto en entornos domésticos como industriales, tiene un impacto directo e inmediato en la creciente y compleja red de distribución eléctrica a la que se conectan. De aquí la necesidad de analizar la calidad de la señal eléctrica y su energía asociada en la propia red e instalaciones afectadas. Por otra parte, la evolución exponencial de microcontroladores y micro PC´S y su aplicación al procesado de señales, convierte a estos dispositivos en candidatos excepcionales para cubrir la mencionada necesidad del análisis de la calidad eléctrica. Esta es justamente la propuesta que se hace en este trabajo. La detección de las perturbaciones eléctricas de mayor incidencia en la calidad de la señal de red se puede realizar de diferentes formas. En este caso, se propone el uso de una potente herramienta matemática como es la Transformada Wavelet (TW), con una contrastada aplicabilidad en este campo. Su traducción a nivel de programación mediante un complejo algoritmo es implementada en dispositivos de bajo coste, particularmente en Arduino y Raspberry Pi. A partir de este algoritmo es posible la detección, análisis y clasificación de distintas perturbaciones eléctricas de forma más intuitiva. Se ha diseñado un sistema capaz de adquirir y analizar la señal de la tensión eléctrica y monitorizar dichos resultados, demostrando la aptitud de estos sistemas de bajo coste para dicho análisis.The massive use of electronic devices, both in domestic and industrial environments, has a direct and immediate impact on the electrical network in which they are connected. This fact generates the need for a power quality analysis in the electrical distribution network and affected installations. On the other hand, the exponential evolution of microcontrollers and micro PC'S and their application to signal processing, makes these devices exceptional candidates to cover the aforementioned power quality analysis. This is precisely the proposal made in this work. The detection of electrical disturbances with greater incidence in power quality can be made in different ways. In this case, the use of a powerful mathematical tool such as the Wavelet Transform (WT), with a proven applicability in this field, is proposed. Its translation at the programming level through a complex algorithm is implemented in low cost devices, particularly in Arduino and Raspberry Pi. From this algorithm it is possible to detect, analyze and classify different electrical disturbances in a more intuitive way. A system capable of acquiring and analyzing the voltage signal, as well as monitoring the results, has been designed, showing the capacity of these low cost devices for such analysis.Plan Propio de la Universidad de Sevilla Proyecto: 2017/0000096