Arquitectura, urbanismo y obras públicas civiles y militares en el Atlas Geográfico de España de Tomás López de 1804

This manuscript presents a novel analysis that deals about how architecture, urban planning and civil and military public works are represented in Geographic Atlas of Spain 1804 (AGE) of Tomas Lopez. For this it has been characterized different map symbols appearing on maps, which are the benchmarks for analysis and transmit accurate information on the shape and meaning of what is represented. So, more than one hundred different symbols were found. This gives an idea of the great detail and richness of the information contained in AGE. A deeper analysis shows that eighteen of them are equivalent to other previous cartographic symbols. These were from Chevalier, D’Anville teacher, who in turn was the teacher Thomas Lopez in Paris. Additionally, we found that there are several symbols with similarity to their corresponding of the Ordinances of the Royal Corps of Engineers from 1803.El objetivo que planteamos es analizar cómo Tomás López representó en su Atlas Geográfico de España (AGE) de 1804, la arquitectura, el urbanismo y las obras públicas civiles y militares, un análisis hasta el momento inédito. Para ello se han caracterizado los diferentes símbolos cartográficos que aparecen en los mapas, que constituyen los parámetros de referencia del análisis y transmiten información fidedigna de la forma y significado de lo representado. Para esas tipologías se han encontrado ciento trece símbolos diferentes, lo que da idea de la minuciosidad y riqueza de la información contenida en los mapas. Dieciocho de ellos, son equivalentes con otros tantos símbolos cartográficos de Chevalier, maestro de D’Anville, de quien Tomás López fue discípulo en París. También hay una similitud entre cuatro símbolos del AGE con sus correspondientes signos de las Ordenanzas del Real Cuerpo de Ingenieros de 1803

Five-year trajectories of multimorbidity patterns in an elderly Mediterranean population using Hidden Markov Models

This is the final version. Available on open access from Nature Research via the DOI in this recordThis study aimed to analyse the trajectories and mortality of multimorbidity patterns in patients aged 65 to 99 years in Catalonia (Spain). Five year (2012–2016) data of 916,619 participants from a primary care, population-based electronic health record database (Information System for Research in Primary Care, SIDIAP) were included in this retrospective cohort study. Individual longitudinal trajectories were modelled with a Hidden Markov Model across multimorbidity patterns. We computed the mortality hazard using Cox regression models to estimate survival in multimorbidity patterns. Ten multimorbidity patterns were originally identified and two more states (death and drop-outs) were subsequently added. At baseline, the most frequent cluster was the Non-Specific Pattern (42%), and the least frequent the Multisystem Pattern (1.6%). Most participants stayed in the same cluster over the 5 year follow-up period, from 92.1% in the Nervous, Musculoskeletal pattern to 59.2% in the Cardio-Circulatory and Renal pattern. The highest mortality rates were observed for patterns that included cardio-circulatory diseases: Cardio-Circulatory and Renal (37.1%); Nervous, Digestive and Circulatory (31.8%); and Cardio-Circulatory, Mental, Respiratory and Genitourinary (28.8%). This study demonstrates the feasibility of characterizing multimorbidity patterns along time. Multimorbidity trajectories were generally stable, although changes in specific multimorbidity patterns were observed. The Hidden Markov Model is useful for modelling transitions across multimorbidity patterns and mortality risk. Our findings suggest that health interventions targeting specific multimorbidity patterns may reduce mortality in patients with multimorbidity.Carlos III Institute of Health, Ministry of Economy and Competitiveness (Spain)European Regional Development FundDepartment of Health of the Catalan GovernmentCatalan Governmen

Early to mid-Holocene spatiotemporal vegetation changes and tsunami impact in a paradigmatic coastal transitional system (Doñana National Park, southwestern Europe)

Ministry of Economy and Competitiveness, Spanish National Park Autonomous Organism, Ministry of Natural, Rural and Marine Environment and Fundación Sénec

Quantitative study of hydration of C3S and C2S by thermal analysis. Evolution and composition of C-S-H gels formed

This research is part of a European project (namely, CODICE project), main objective of which is modelling, at a multi-scale, the evolution of the mechanical performance of non-degraded and degraded cementitious matrices. For that, a series of experiments were planned with pure synthetic tri-calcium silicate (C3S) and bi-calcium silicate (C2S) (main components of the Portland cement clinker) to obtain different calcium–silicate–hydrate (C–S–H) gel structures during their hydration. The characterization of those C–S–H gels and matrices will provide experimental parameters for the validation of the multi-scale modelling scheme proposed. In this article, a quantitative method, based on thermal analyses, has been used for the determination of the chemical composition of the C–S–H gel together with the degree of hydration and quantitative evolution of all the components of the pastes. Besides, the microstructure and type of silicate tetrahedron and mean chain length (MCL) were studied by scanning electron microscopy (SEM) and 29Si magic-angle-spinning (MAS) NMR, respectively. The main results showed that the chemical compositions for the C–S–H gels have a CaO/SiO2 M ratio almost constant of 1.7 for both C3S and C2S compounds. Small differences were found in the gel water content: the H2O/SiO2 M ratio ranged from 2.9 ± 0.2 to 2.6 ± 0.2 for the C3S (decrease) and from 2.4 ± 0.2 to 3.2 ± 0.2 for the C2S (increase). The MCL values of the C–S–H gels, determined from 29Si MAS NMR, were 3.5 and 4 silicate tetrahedron, for the hydrated C3S and C2S, respectively, remaining almost constant at all hydration periods

Relationship between the Sensory-Determined Astringency and the Flavanolic Composition of Red Wines

[EN] The relationship between the proanthocyanidin profile and the perceived astringency was assessed in 13 commercial Tempranillo red wines. The concentration and compositional information were obtained by liquid chromatography with diode array detection coupled to electrospray ionization mass spectrometry after acid-catalyzed depolymerization of wine proanthocyanidins in the presence of excess phloroglucinol. Statistical analysis of the results showed significant correlations between sensory and chemical determinations. Astringency was more affected by the subunit composition than by the total concentration or the average degree of polymerization of wine proanthocyanidins. Higher proportions of epicatechin (EC) subunits in extension positions and gallocatechin (GC) subunits in terminal positions were shown to increase astringency. On the contrary, the amount of epigallocatechin (EGC) in both extension and terminal positions was negatively correlated with the perceived astringency

ICTON 2018

Producción CientíficaA genetic algorithm is proposed to map virtual network functions in computing resources over 5G networks with an optical backhauling system. The algorithm outperforms other proposals in terms of blocking ratio and active CPU cores utilization.Ministerio de Economía, Industria y Competitividad (Projects TEC2014- 53071-C3 -2-P, TEC2017-84423- C3 -1-P, TEC2015-71932- REDT)Ministerio de Educación, Cultura y Deporte (Proyects BES -2015-074514 and FPU14/04227

Trichinellosis survey in wild fauna from various regions of Spain

Se presentan los resultados del estudio de vigilancia epidemiológica de triquinelosis (Trichinella spiralis y T. britovi) en fauna salvaje (jabalí y zorro), llevado a cabo en Catalunya (2006-2008), La Rioja (2001-2003) y Castilla-La Mancha (2007-2008). Las prevalencias fluctúan entre 0,7-0,93 % en jabalí y 0,64-4,2 % en zorro. Póster. EPI 27. Abstract Book. 4th Annual Scientific Meeting (2008). MED-VET-NET. Saint-Malo, France. Autores: Manzano-Lorenzo R., Nogal-Ruíz J.J., Fonseca-Salamanca F., García-Sancho R.N., Arroyo-Díaz J.M., Jiménez S., Fàbregas X., Colomer A., Bolás-Fernández F., Martínez-Fernández A.M. 520 3_ $a Es presenten els resultats de l'estudi de vigilància epidemiològica de triquinel·losis (Trichinella spiralis y T. britovi) en fauna salvatge (porc senglar i guineu), portat a terme a Catalunya (2006-2008), La Rioja (2001-2003) i Castilla-La Mancha (2007-2008). Les prevalences fluctuen entre 0,7-0,93 % en senglar i 0,64-4,2 % en guineu. Pòster. EPI 27. Abstract Book. 4th Annual Scientific Meeting (2008). MED-VET-NET. Saint-Malo, France

Pharmacovigilance in children in Camagüey Province, Cuba

Purpose: Our aim was to describe the adverse drug reactions (ADRs) detected following increased education about pharmacovigilance and drug toxicity in children in Camagüey Province, Cuba. Methods: Over a period of 24 months (January 2009 to December 2010), all reports of suspected ADRs in children to the Provincial Pharmacovigilance Centre in Camagüey Province were analysed. ADRs were classified in relation to causality and severity. Results: There were 533 reports involving suspected ADRs in children in the period. Almost one third of the reports received were classified as moderate (155, 29%) or severe (10, 2%). There was one fatality in association with the use of ceftriaxone. Vaccines and antibiotics were responsible for most of the ADR reports (392, 74%) and for all ten severe ADRs. After an intensive educational package, both within the community and the Children’s Hospital, the number of reports increased from 124 in 2008 to 161 in 2009 and 372 in 2010. This was equivalent to a reporting rate of 879 and 2,031 reports per million children per year for 2009 and 2010, respectively. Conclusions: The incidence of ADRs in children Camagüey Province, Cuba, is greater than previously reported. An educational intervention about pharmacovigilance and drug toxicity in children can improve the reporting of ADRs