92 research outputs found
Analyse de la traduction chinoise des verbes visuels dans L’étranger
Vecteurs fondamentaux de la perception humaine, les verbes visuels possèdent une valeur singulière en traduction littéraire. Notre étude interroge les stratégies traductives et les fonctions narratives de ces unités lexicales à travers l’analyse contrastive de L’Étranger de Camus, archétype du roman existentialiste, et de sa version chinoise par Liu Mingjiu. L’original français déploie une palette perceptive précise de voir et de regarder, qui structure simultanément la diégèse et module les affects. L’examen de la traduction chinoise révèle comment ces verbes actualisent des reconstructions interlinguistiques complexes et assument une polyfonctionnalité textuelle
Pro-inflammatory miR-223 mediates the cross-talk between the IL23 pathway and the intestinal barrier in inflammatory bowel disease
Genes that showed greater than four-fold upregulation in IBD. (XLSX 28 kb
Different active exogenous carbons improve the yield and quality of roses by shaping different bacterial communities
The application of exogenous organic carbon represents a significant strategy for enhancing soil fertility and promoting sustainable agricultural development. This approach modifies the physicochemical properties of soil and influences microbial community structures, consequently improving crop yield and quality. Nevertheless, the mechanisms underlying microbial community responses to various forms of active exogenous organic carbon remain poorly understood and require further investigation. A 1-year follow-up experiment was conducted to examine the effects of different carbon sources on the yield and quality of cut roses, along with the characteristics of the soil bacterial community. The results indicated that applying organic fertiliser and biochar significantly enhanced the productivity of cut roses, demonstrating a sustained growth-promoting effect. Organic fertiliser provides more active, readily oxidisable organic carbon to the soil compared to biochar. In contrast, biochar supplies stable organic carbon, including inert organic carbon that is difficult to oxidise, firm organic carbon (FOC), and total inert organic carbon, which has a high degree of humification that significantly exceeds that of organic fertiliser. The application of biochar and organic fertiliser not only altered the abundance, diversity, and composition of the rhizosphere microbial community but also enriched beneficial microorganisms. Redundancy analysis results indicated that FOC, available phosphorus, and soil organic matter were the primary factors influencing the bacterial community. The results of this study demonstrated that exogenous organic carbon exerted positive and indirect effects on crop yield by influencing soil properties and bacterial communities. These findings provide novel evidence supporting the rational application of biochar and organic fertilisers as a means to promote agricultural sustainability in red soil regions
Compound K Inhibits Autophagy-Mediated Apoptosis Through Activation of the PI3K-Akt Signaling Pathway Thus Protecting Against Ischemia/Reperfusion Injury
Background/Aims: A series of reports revealed that autophagy and apoptosis exerted detrimental effects on the pathology of cardiac ischemia/reperfusion (I/R) injury. Ginsenoside compound K (CK), a major intestinal metabolite underlying the pharmacological actions of orally administered ginseng, has a protective effect against myocardial I/R injury. However, the molecular mechanisms by which CK protects against I/R injury remain unclear. In this study, we hypothesized that the cardioprotective effects of CK against I/R injury are mediated by inhibiting autophagy/apoptosis-related signaling pathways in H9c2 cardiomyocyte cells. Methods: H9c2 cells were incubated with CK and exposed to I/R. Cell viability and damage was analyzed by MTT and lactate dehydrogenase assays. Reactive oxygen species (ROS) generation, mitochondrial damage, and cell apoptosis were analyzed by flow cytometry and TUNEL staining. The expression of autophagy, apoptosis, and related signaling proteins was analyzed by Western blotting and immunofluorescence staining. Results: CK pretreatment promoted cell viability and attenuated ROS accumulation and intracellular mitochondrial damage induced by I/R injury Moreover, CK reduced autophagy by regulating the formation of phagocytic precursors to autophagosomes and also inhibited apoptosis through a mitochondrial-mediated pathway. Additionally the cardioprotective effect of CK against I/R injury was mainly through the activation of the PI3K-Akt signaling pathway. Conclusions: CK pretreatment inhibits autophagy-mediated apoptosis induced by I/R injury through the activation of the PI3K-Akt signaling pathway, which reveals that CK may be one of the key bioactive ingredients of ginseng for the treatment of myocardial I/R injury
Association of anthropometry and weight change with risk of dementia and its major subtypes : A meta-analysis consisting 2.8 million adults with 57 294 cases of dementia
Uncertainty exists regarding the relation of body size and weight change with dementia risk. As populations continue to age and the global obesity epidemic shows no sign of waning, reliable quantification of such associations is important. We examined the relationship of body mass index, waist circumference, and annual percent weight change with risk of dementia and its subtypes by pooling data from 19 prospective cohort studies and four clinical trials using meta-analysis. Compared with body mass index-defined lower-normal weight (18.5-22.4 kg/m(2)), the risk of all-cause dementia was higher among underweight individuals but lower among those with upper-normal (22.5-24.9 kg/m(2)) levels. Obesity was associated with higher risk in vascular dementia. Similarly, relative to the lowest fifth of waist circumference, those in the highest fifth had nonsignificant higher vascular dementia risk. Weight loss was associated with higher all-cause dementia risk relative to weight maintenance. Weight gain was weakly associated with higher vascular dementia risk. The relationship between body size, weight change, and dementia is complex and exhibits non-linear associations depending on dementia subtype under scrutiny. Weight loss was associated with an elevated risk most likely due to reverse causality and/or pathophysiological changes in the brain, although the latter remains speculative.Peer reviewe
Ag modified g-C<sub>3</sub>N<sub>4</sub> composite entrapped PES UF membrane with visible-light-driven photocatalytic antifouling performance
Membrane fouling is still the main obstacle for the wider application of membrane processes.</p
Step-scheme heterojunction g-C3N4/TiO2 for efficient photocatalytic degradation of tetracycline hydrochloride under UV light
Design scheme of ship risk prediction model from the perspective of artificial intelligence
Abstract
Vessels sailing at sea are full of risks, accidents occur frequently, and it is easy to cause heavy casualties and property losses. To this end, this article focuses on how to build a high-precision and rapid ship risk prediction model, and proposes a design plan for a ship risk prediction model based on big data and artificial intelligence. The plan includes a basic data layer, a technical business layer, and an application layer, with a focus on The technical research scheme of the graph representation model construction of the ship risk big data, the dynamic graph matching algorithm and the ship risk prediction is elaborated in detail, and finally the experimental design method of the scheme is given. The design scheme proposed in this paper can provide reference and inspiration for the research and development of marine risk system.</jats:p
Real-time shear wave elastography in measuring normal ileocolon intestinal wall stiffness using colonoscopy as reference: A single-center research
Purpose: To investigate the feasibility of real-time shear wave elastography (SWE) in evaluating intestinal wall stiffness, and to establish the threshold SWE value of normal intestinal wall and explore the influencing factors of intestinal SWE. Method: 659 subjects who underwent intestinal SWE and colonoscopy were retrospectively enrolled. The wall elasticity of colonoscopy-confirmed normal/abnormal intestinal segment was measured by transabdominal SWE. Measurement reliability was evaluated by the intraclass correlation coefficient (ICC). The threshold value of SWE in differentiating normal and abnormal intestine was determined using ROC curve analysis with the largest Youden index, and the diagnostic performance of this threshold was evaluated. We explored the effects of gender, age, depth and type of the targeted intestinal segment on the intestinal wall elasticity by t test and logistic linear regression analysis. Results: The technical success rate of SWE examination is 95.3 % (628/659). The mean SWE value of normal intestinal walls is (5.45 ± 1.34) kPa, which was significantly lower than that of abnormal ones (15.38 kPa±7.22, P < 0.001). Using 8.1 kPa as the threshold, the sensitivity and specificity were 93.5 % and 96.0 % with an AUC of 94.8 %. The overall ICC for SWE measurements was 0.933. Gender (ß=0.278, P = 0.013), depth (ß=0.220, P = 0.043) and type of the targeted segment (ß=0.522, P < 0.001) was associated with the SWE value of intestinal wall, but age was not (ß=0.050, P = 0.484). Conclusions: SWE is feasible in evaluating the stiffness of intestinal wall with high reliability. The SWE threshold value differentiating normal intestinal wall and abnormal intestinal wall is 8.1 kPa
Design tremella-like Ni-Co selenide with wonderful electrochemical performances as supercapacitor cathode material
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