770 research outputs found
Rape Crisis Center Professionals\u27 Perception of Sexual Violence Policy: A Qualitative Analysis
The purpose of this study is to collect information about the perceptions of rape crisis center professionals regarding the current policies surrounding sexual violence crimes that victimize people over the age of 18. This research aims to gather information about effective and ineffective policies from professionals who are first- responders to sexual assaults
Estimation of μy Using the General Regression Model (in sampling)
The methods of ratio and regression estimators discussed by Cochran(l977) are given as background materials and extended to the estimation of µy, the population mean of the Y\u27s, using a general regression model.
The propagation of error technique given by Deming(l948) is used as an approximation to find the variance of the estimator µy.
Examples are given for each of the various models. Variances of μy are calculated and compare
Court protocol in Nara Japan: an annotated translation of the <i>Giseiryō</i> and the <i>Ebukuryō</i>
This article furnishes the analysis and the philological translation for the first time into English of two laws contained in Book 7 of the Yōrōryō (Yōrō Administrative Code, 718), i.e. the Giseiryō 儀制令 (Law on Ceremonies and Regulations) and the Ebukuryō 衣服令 (Law on Robes and Garments). These two laws are pivotal in regulating the court etiquette, not only regarding the behavior but also the appearance of the political elites, as etiquette and attires define the hierarchy and the interpersonal relations between aristocracy, officialdom, and personnel down to the servants. On the one hand, the two laws highlight some basic differences between the Japanese rulers and their Chinese counterparts; on the other hand, the emphasis on ceremonies, regulations, and attires molded the subsequent Heian court society, as can be easily inferred from the significant production of texts emphasizing rituals and etiquette, such as manuals on protocol and precedents and journals written by court officials
O cidadão ideal no Liberalismo de John Rawls
O objetivo deste artigo é um estudo do cidadão ideal na obra O liberalismo político de John Rawls. No universo teórico do liberalismo político, o pensamento de John Rawls corresponde aum avanço significativo na teorização da sociedade democrática. Especialmente em O liberalismo político há uma contribuição valiosa em torno da representação do cidadão em uma sociedade bem ordenada, de base constitucional. Nesse quadro interpretativo, destaca-se o conceito de consenso sobreposto, indicado comoforma superior ao consenso constitucional
Metabolic genes in hepatocellular carcinoma developement
Tesis doctoral inédita leída en la Universidad Autónoma de Madrid, Facultad de Ciencias, Departamento de Biología Molecular. Fecha de lectura: 08-09-2016Esta tesis tiene embargado el acceso al texto completo hasta el 09-09-2018Hepatocellular carcinoma (HCC) is the second leading cause of death for cancer worldwide. Several studies on hepatocellular carcinoma epidemiology linked this malignancy with obesity and metabolic disorders. However, little is known about the molecular mechanisms responsible for this connection. The main purpose of this thesis is to elucidate the role of Jnk1 and Ppara, two important metabolic genes, in hepatocellular carcinoma development.
Adipose tissue is the most important organ for lipid storage; during obesity it undergoes to a substantial remodeling. JNK1 is known to control IL-6 production in the adipose tissue during obesity and its depletion in adipocyte protects against liver steatosis, a predisposing factor for HCC development. We demonstrate that adipose tissue JNK1 in normal diet can trigger hepatocellular carcinoma development. In fact, the deletion of JNK1 in adipose tissue increases circulating levels of adiponectin, which in turn activates AMPKα and p38α in hepatocytes, protecting against chemical-induced tumor development. Our results highlight the relevance of adipose tissue in liver cancer development and the central role that JNK1 plays in this crosstalk.
PPARα is a nuclear receptor of fatty acids. It is highly expressed in the liver and obesity induces its activation. However, PPARα role in liver carcinogenesis is controversial. Here we show that PPARα activation promotes obesity-associated hepatic cancer. Mice lacking PPARα are protected against chemical-induced hepatocellular carcinoma when fed a high fat diet. Additionally, bone marrow transplantation experiments reveal no significant contribution of inflammatory cells, suggesting a cell-autonomous function of PPARα in hepatocytes. Hepatic PPARα activation, induced by Jnk1 and Jnk2 deletion, is sufficient to cause spontaneous liver cancer, confirming a central role of PPARα activation in liver tumorigenesis. Our results provide a molecular mechanism linking metabolic disorders with liver cancer, emphasizing a central role for PPARα in the connectionThe support received from the following Grants and Fellowships has permitted to develop this PhD work: La Caixa International PhD Fellowship Program, 2010 Cal
CANGAÇO E MEMÓRIA COLETIVA NO NORDESTE BRASILEIRO
Resenha do livro: CLEMENTE, Marcos E. de. Lampiões acesos: O cangaço na memória coletiva. São Cristóvão: Editora UFS; Aracaju: Fundação Oviêdo Teiveira, 2009
O INDIVÍDUO NA CONDIÇÃO PÓS-MODERNA: a perspectiva critica de Zygmunt Bauman
O objetivo deste artigo é um estudo do indivíduo na era pós-moderna na perspectiva de Zygmunt Bauman. Segundo este último, o cidadão se converte em um indivíduo consumidor, com enorme prejuízos para a dimensão mora
A Complexidade do populismo: O exemplo da Venezuela
Comentário crítico sobre o artigo “Populismo radical e processo bolivariano: o conceito de populismo de Ernesto Laclau nas análises da Venezuela contemporânea”, de Vicente Neves da Silva Ribeiro
Rilevazione di transazioni fraudolente nell’e-commerce basata sull’apprendimento automatico
In questa tesi esplorerò il problema degli ordini fraudolenti nell’e-commerce,
gli impatti economici che hanno sulle aziende e i metodi attuali utilizzati
per scovarli. Analizzerò anche i modelli di machine learning e come questi
possono essere utilizzati per identificare gli ordini fraudolenti con maggiore
precisione e come valutarli in questo contesto. L’obiettivo `e fornire una com-
prensione più profonda del problema degli ordini fraudolenti nell’e-commerce
e analizzare metodi per affrontarlo attraverso l’utilizzo di tecnologie avanzate.
Per fare ciò, utilizzerò un modello di machine learning per fare delle predizioni su un dataset di transazioni open source, per capire quali sono i
fattori chiave per ottenere buone prestazioni, con l’obiettivo di massimizzare
i guadagni e ridurre al minimo i costi. Dopo aver analizzato diversi modelli,
verranno valutate le performance del miglior modello trovato su un dataset
di transazioni di un’azienda di fashion cliente dell’azienda per cui lavoro, con
lo scopo di realizzare un prodotto appetibile e vendibile da proporre a questo
cliente e in caso di successo anche ad altri
Pragmatismo e Razão Comunicacional: uma contribuição ao Aprendizado Educacional
The aim of this article is to study the educational potential of communicative reason. Since the emergence of pragmatism, there has been a group of thinkers who question the practice based on reason centered on the subject. Initiated in an environment of confrontation with knowledge arising from religious authority, the Enlightenment reason centered on the subject is based on the certainty of universal reason, present in the subjects. With pragmatism there are new forms of rationality, with emphasis on a type of reason that is formed in intersubjective relations. In Habermas, in particular, communicative reason promotes new conceptions about "truth" and "knowledge". Understood in the educational field, communicative reason results in a new learning process.O objetivo desse artigo é um estudo sobre as potencialidades educativas da razão comunicativa. Desde o surgimento do pragmatismo, presencia-se um grupo de pensadores que questiona a prática fundamentada na razão centrada no sujeito. Iniciada no ambiente de confronto com o saber advindo da autoridade religiosa, a razão Iluminista centrada no sujeito se ampara na certeza da razão universal, presente nos sujeitos. Com o pragmatismo há novas formas de racionalidade, com destaque para um tipo de razão que se forma nas relações intersubjetivas. Em Habermas, particularmente, a razão comunicativa promove novas concepções sobre a “verdade” e o “conhecimento”. Entendida no campo educacional, a razão comunicativa resulta em um novo processo de aprendizado
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