Оценка надежности высоконадежных систем с учетом ЗИП

Предложены приближенные верхние и нижние оценки коэффициента готовности высоконадежной восстанавливаемой системы со структурной избыточностью. Полученные расчетные соотношения могут использоваться для оценки надежности высоконадежных систем с учетом различных стратегий пополнения ЗИП

Developmental delay in early childhood is associated with visual-constructive skills at school age in a Brazilian cohort

Abstract We investigated differences in IQ and visual-constructive skills in school-age children evaluated as developmentally delayed or typically developed in early childhood. Sixty-four participants from a Brazilian cohort were evaluated in IQ (Wechsler Abbreviated Scale of Intelligence) and tasks of visual-spatial memory and visual-constructive skills through the Benton Visual Retention Test (BVRT) at school age. Neuropsychomotor development at 4 years of age was measured by Denver II. Developmentally delayed children showed lower IQs, lower scores, and more errors in copy and memory BVRT tasks when compared to typically developed children. Delay in neuropsychomotor development in early childhood may affect the subsequent cognitive development of children

Pulse wave velocity testing in the Baltimore longitudinal study of aging.

Carotid-femoral pulse wave velocity is considered the gold standard for measurements of central arterial stiffness obtained through noninvasive methods(1). Subjects are placed in the supine position and allowed to rest quietly for at least 10 min prior to the start of the exam. The proper cuff size is selected and a blood pressure is obtained using an oscillometric device. Once a resting blood pressure has been obtained, pressure waveforms are acquired from the right femoral and right common carotid arteries. The system then automatically calculates the pulse transit time between these two sites (using the carotid artery as a surrogate for the descending aorta). Body surface measurements are used to determine the distance traveled by the pulse wave between the two sampling sites. This distance is then divided by the pulse transit time resulting in the pulse wave velocity. The measurements are performed in triplicate and the average is used for analysis

Prevalence, clinical correlates, and functional impact of subaortic ventricular septal bulge (from the Baltimore Longitudinal Study of Aging).

A localized hypertrophy of the subaortic segment of the ventricular septum-ventricular septal bulge (VSB)-has been frequently described in series of elderly population, but its prevalence with age, clinical correlates, and impact on cardiac function and exercise capacity remain uncertain. We explored these associations in a cross-sectional sample without known cardiac disease from the Baltimore Longitudinal Study of Aging. We randomly selected 700 participants (50% men, mean age 64 \ub1 15, range 26 to 95 years) and reviewed their echocardiograms. We identified 28 men and 21 women with VSB (7% overall prevalence). The prevalence of VSB significantly increased with age in both genders (p <0.0001). In multivariate logistic regression including hypertension and other cardiovascular risk factors, only age displayed a significant independent association with VSB (OR 1.06 per year, 95% confidence interval 1.03 to 1.10, p = 0.0001). After multiple adjustments, participants with VSB compared with those without had enhanced global left ventricular contractility (fractional shortening 41 \ub1 1.3 vs 38 \ub1 0.3%, p = 0.04; ejection fraction 71 \ub1 1.6 vs 67 \ub1 0.4%, p = 0.06; systolic velocity of the mitral annulus 8.4 \ub1 0.1 vs 8.9 \ub1 0.3, p = 0.06), and larger aortic root diameters (3.3 \ub1 0.06 vs 3.1 \ub1 0.02 cm, p = 0.02). In subgroup of participants who completed a maximal treadmill test (177 women and 196 men), those with VSB (19, 5.1%) had significantly lower peak oxygen consumption than their counterparts (19.6 \ub1 3.8 vs 22.9 \ub1 6.6 ml/kg/min, p = 0.03). However, this association was no longer significant after multiple adjustments. In conclusion, the presence of VSB is independently associated with older age and determines enhanced left ventricular contractility, without any evident impact on exercise capacity

The relation of elementary school children’s externalizing behaviour to emotion attributions, evaluation of consequences, and moral reasoning

This study examined the relation of elementary-school children's externalizing behaviour to emotion attributions, evaluation of consequences, and moral reasoning. Externalizing behaviour was rated by the parents using the Child Behaviour Checklist (CBCL/4 - 18). Moral development was assessed by three stories describing different types of rule violation and a moral conflict in friendship including obligations and self-interest. The children were asked about the emotions they would attribute to the hypothetical victimizer (or protagonist) and the self-as-victimizer (or protagonist), the evaluation of the interpersonal consequences of the rule violation (or action decision) as well as their justifications. Boys who made selfish action decisions and attributed positive emotions to the protagonist of the moral dilemma displayed more externalizing behaviour than girls. Furthermore, boys with consistent moral (negative) emotion attributions to the self-as-victimizer across the rule violations showed less externalizing behaviour than boys with inconsistent moral emotion attributions. Younger children who anticipated negative interpersonal consequences of transgressions displayed higher rates of externalizing behaviour than younger children who anticipated less negative consequences. Moral reasons in the context of emotion attributions to the self-as-victimizer were negatively associated with externalizing behaviour