Schur elements for the Ariki-Koike algebra and applications

We study the Schur elements associated to the simple modules of the Ariki-Koike algebra. We first give a cancellation-free formula for them so that their factors can be easily read and programmed. We then study direct applications of this result. We also complete the determination of the canonical basic sets for cyclotomic Hecke algebras of type $G(l,p,n)$ in characteristic 0.Comment: The paper contains the results of arXiv:1101.146

Fifty-kDa Hyaluronic Acid Upregulates Some Epidermal Genes without Changing TNF-α Expression in Reconstituted Epidermis

Background: Due to its strong water binding potential, hyaluronic acid (HA) is a well-known active ingredient for cosmetic applications. However, based on its varying molecular size, skin penetration of HA may be limited. Recent studies have demonstrated that low-molecular-weight HA (LMW HA) may show a certain proinflammatory activity. We thus aimed to characterize an LMW-sized HA molecule that combines strong anti-aging abilities with efficient skin penetration but lacks potential proinflammatory effects. Methods: Total RNA and total protein were isolated from reconstituted human epidermis following incubation with HAs of various molecular weights (20, 50, 130, 300, 800 and 1,500 kDa). Tumor necrosis factor-alpha expression was determined using quantitative PCR. Genonnic and proteomic expression of various junctional proteins was determined using Affymetrix and common Western blotting techniques. Results: LMW HA of approximately 50 kDa did not significantly alter tumor necrosis factor-alpha expression compared to 20-kDa HA, but revealed significantly higher skin penetration rates than larger sized HA associated with increased expression of genes and proteins known to be involved in tight junction formation and keratinocyte cohesion. Conclusion: LMW HA of approximately 50 kDa shows better penetration abilities than larger-sized HA. In addition, LMW HA influences the expression of various genes including those contributing to keratinocyte differentiation and formation of intercellular tight junction complexes without showing proinflammatory activity. These observations contribute to current knowledge on the effects of LMW HA on keratinocyte biology and cutaneous physiology. Copyright (C) 2011 S. Karger AG, Base

Characterization of global fields by Dirichlet L-series

We prove that two global fields are isomorphic if and only if there is an isomorphism of groups of Dirichlet characters that preserves L-series

Alternating groups and moduli space lifting Invariants

Main Theorem: Spaces of r-branch point 3-cycle covers, degree n or Galois of degree n!/2 have one (resp. two) component(s) if r=n-1 (resp. r\ge n). Improves Fried-Serre on deciding when sphere covers with odd-order branching lift to unramified Spin covers. We produce Hurwitz-Torelli automorphic functions on Hurwitz spaces, and draw Inverse Galois conclusions. Example: Absolute spaces of 3-cycle covers with +1 (resp. -1) lift invariant carry canonical even (resp. odd) theta functions when r is even (resp. odd). For inner spaces the result is independent of r. Another use appears in, http://www.math.uci.edu/~mfried/paplist-mt/twoorbit.html, "Connectedness of families of sphere covers of A_n-Type." This shows the M(odular) T(ower)s for the prime p=2 lying over Hurwitz spaces first studied by, http://www.math.uci.edu/~mfried/othlist-cov/hurwitzLiu-Oss.pdf, Liu and Osserman have 2-cusps. That is sufficient to establish the Main Conjecture: (*) High tower levels are general-type varieties and have no rational points.For infinitely many of those MTs, the tree of cusps contains a subtree -- a spire -- isomorphic to the tree of cusps on a modular curve tower. This makes plausible a version of Serre's O(pen) I(mage) T(heorem) on such MTs. Establishing these modular curve-like properties opens, to MTs, modular curve-like thinking where modular curves have never gone before. A fuller html description of this paper is at http://www.math.uci.edu/~mfried/paplist-cov/hf-can0611591.html .Comment: To appear in the Israel Journal as of 1/5/09; v4 is corrected from proof sheets, but does include some proof simplification in \S

Mind Perception Is the Essence of Morality

Mind perception entails ascribing mental capacities to other entities, whereas moral judgment entails labeling entities as good or bad or actions as right or wrong. We suggest that mind perception is the essence of moral judgment. In particular, we suggest that moral judgment is rooted in a cognitive template of two perceived minds—a moral dyad of an intentional agent and a suffering moral patient. Diverse lines of research support dyadic morality. First, perceptions of mind are linked to moral judgments: dimensions of mind perception (agency and experience) map onto moral types (agents and patients), and deficits of mind perception correspond to difficulties with moral judgment. Second, not only are moral judgments sensitive to perceived agency and experience, but all moral transgressions are fundamentally understood as agency plus experienced suffering—that is, interpersonal harm—even ostensibly harmless acts such as purity violations. Third, dyadic morality uniquely accounts for the phenomena of dyadic completion (seeing agents in response to patients, and vice versa), and moral typecasting (characterizing others as either moral agents or moral patients). Discussion also explores how mind perception can unify morality across explanatory levels, how a dyadic template of morality may be developmentally acquired, and future directions

Is spoken language all-or-nothing? Implications for future speech-based human-machine interaction

Recent years have seen significant market penetration for voice-based personal assistants such as Apple’s Siri. However, despite this success, user take-up is frustratingly low. This article argues that there is a habitability gap caused by the inevitablemismatch between the capabilities and expectations of human users and the features and benefits provided by contemporary technology. Suggestions aremade as to how such problems might be mitigated, but a more worrisome question emerges: “is spoken language all-or-nothing”? The answer, based on contemporary views on the special nature of (spoken) language, is that there may indeed be a fundamental limit to the interaction that can take place between mismatched interlocutors (such as humans and machines). However, it is concluded that interactions between native and non-native speakers, or between adults and children, or even between humans and dogs, might provide critical inspiration for the design of future speech-based human-machine interaction

Beliefs about others' intentions determine whether cooperation is the faster choice

Is collaboration the fast choice for humans? Past studies proposed that cooperation is a behavioural default, based on Response Times (RT) findings. Here we contend that the individual’s reckoning of the immediate social environment shapes her predisposition to cooperate and, hence, response latencies. In a social dilemma game, we manipulate the beliefs about the partner’s intentions to cooperate and show that they act as a switch that determines cooperation and defection RTs; when the partner’s intention to cooperate is perceived as high, cooperation choices are speeded up, while defection is slowed down. Importantly, this social context effect holds across varying expected payoffs, indicating that it modulates behaviour regardless of choices’ similarity in monetary terms. Moreover, this pattern is moderated by individual variability in social preferences: Among conditional cooperators, high cooperation beliefs speed up cooperation responses and slow down defection. Among free-riders, defection is always faster and more likely than cooperation, while high cooperation beliefs slow down all decisions. These results shed new light on the conflict of choices account of response latencies, as well as on the intuitive cooperation hypothesis, and can help to correctly interpret and reconcile previous, apparently contradictory results, by considering the role of context in social dilemmas

Number Fields Ramified at One Prime

Abstract. For G a finite group and p a prime, a G-p field is a Galois number field K with Gal(K/Q) ∼ = G and disc(K) = ±pa for some a. We study the existence of G-p fields for fixed G and varying p. For G a finite group and p a prime, we define a G-p field to be a Galois number field K ⊂ C satisfying Gal(K/Q) ∼ = G and disc(K) = ±pa for some a. Let KG,p denote the finite, and often empty, set of G-p fields. The sets KG,p have been studied mainly from the point of view of fixing p and varying G; see [Har94], for example. We take the opposite point of view, as we fix G and let p vary. Given a finite group G, we let PG be the sequence of primes where each prime p is listed |KG,p | times. We determine, for various groups G, the first few primes in PG and their corresponding fields. Only the primes p dividing |G | can be wildly ramified in a G-p field, and so the sequences PG which are infinite are dominated by tamely ramified fields. In Sections 1, 2, and 3, we consider the cases when G is solvable with length 1, 2, and ≥ 3 respectively, using mainly class field theory. Section 4 deals wit

HIV infection and drugs of abuse: role of acute phase proteins

Background HIV infection and drugs of abuse such as methamphetamine (METH), cocaine, and alcohol use have been identified as risk factors for triggering inflammation. Acute phase proteins such as C-reactive protein (CRP) and serum amyloid A (SAA) are the biomarkers of inflammation. Hence, the interactive effect of drugs of abuse with acute phase proteins in HIV-positive subjects was investigated. Methods Plasma samples were utilized from 75 subjects with METH use, cocaine use, alcohol use, and HIV-positive alone and HIV-positive METH, cocaine, and alcohol users, and age-matched control subjects. The plasma CRP and SAA levels were measured by ELISA and western blot respectively and the CD4 counts were also measured. Results Observed results indicated that the CRP and SAA levels in HIV-positive subjects who are METH, cocaine and alcohol users were significantly higher when compared with either drugs of abuse or HIV-positive alone. The CD4 counts were also dramatically reduced in HIV-positive with drugs of abuse subjects compared with only HIV-positive subjects. Conclusions These results suggest that, in HIV-positive subjects, drugs of abuse increase the levels of CRP and SAA, which may impact on the HIV infection and disease progression

ZnO Nanorods via Spray Deposition of Solutions Containing Zinc Chloride and Thiocarbamide

In this work we present the results on formation of ZnO nanorods prepared by spray of aqueous solutions containing ZnCl2and thiocarbamide (tu) at different molar ratios. It has been observed that addition of thiocarbamide into the spray solution has great impact on the size, shape and phase composition of the ZnO crystals. Obtained layers were characterized by scanning electron microscopy (SEM) equipped with energy selected backscattered electron detection system (ESB), X-ray diffraction (XRD) and photoluminescence spectroscopy (PL). Small addition of thiocarbamide into ZnCl2solution (ZnCl2:tu = 1:0.25) supports development of significantly thinner ZnO nanorods with higher aspect ratio compared to those obtained from ZnCl2solution. Diameter of ZnO rods decreases from 270 to 100 nm and aspect ratio increases from ∼2.5 to 12 spraying ZnCl2and ZnCl2:tu solutions, respectively. According to XRD, well crystallized (002) orientated pure wurtzite ZnO crystals have been formed. However, tiny ‘spot’—like formations of ZnS were detected on the side planes of hexagonal rods prepared from the thiocarbamide containing solutions. Being adsorbed on the side facets of the crystals ZnS inhibits width growth and promotes longitudinalc-axis growth