Lipoprotein metabolism and LCAT activity in chronic renal failure dogs supplemented with PUFA oils

Due to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to [email protected], referencing the URI of the item.Includes bibliographical references: 44-52.Issued also on microfiche from Lange Micrographics.Serum total cholesterol (TC), lipoprotein cholesterol distribution, and lecithin:cholesterol acyltransferase (LCAT) activities of chronic renal failure dogs were investigated. Control dogs (n = 14) and affected dogs (n = 29) were fed one of three protein/phosphorous restricted diets: low protein canned (LPC), medium protein canned (MPC), or low protein dry (LPD), for 3 to 5 weeks. Basal diets were then supplemented for 6 weeks with menhaden fish oil (MHO) or safflower oil (SFO) in a crossover design which included a 3 week wash-out period. After basal diet acclimation, serum TC increased (paired t-test, p < 0.05) in LPC, MPC, and LPD control groups. At the same time, (X2 lipoprotein cholesterol increased (p < 0.05) in all three control groups. The MPC control dogs also showed an increase (p = 0.01) in cholesterol associated with the (xl fraction after diet acclimation. Among affected dogs, only those receiving the MPC diet showed an elevation (p < 0.01) in serum TC after the basal period. Significant MHO supplement effects included a decrease (p < 0.01) in serum TC in MPC control dogs, and a decrease (p < 0.05) in a2 lipoprotein cholesterol in LPD control dogs. Safflower oil had no significant effect on plasma lipoproteins. No significant differences in serum TC or lipoprotein cholesterol distribution were found between affected and control dogs regardless of basal diet or oil supplementation. Serum LCAT activates were assessed in a subset of MPC dogs; no significant differences between affected and control dogs were revealed. When these two groups were combined, ANOVA revealed an increase in LCAT activities (p < 0.03) after the basal period, and a significant decrease in LCAT activities (p < 0.05) after SFO supplementation. Previously, it was shown that the MPC diet elevated LCAT activities in normal dogs due to its higher fat content; the present group of control and affected dogs confirmed these findings. In the present study, LCAT activates of affected dogs may have been elevated prior to entry because these dogs had been fed renal failure diets which were relatively high in fat before entering the clinical trial

Study Results of University Students in the Context of Experiencing Positive Emotions, Satisfaction and Happiness

An optimal motivation for learning is one of the fundamental prerequisites for study success, it is therefore understandable that experts are still looking for additional ways to positively influence university students in this field. One option is the coherent and deliberate use of the close interdependence of motivational and emotional processes. In our reflections, we assume that the low motivation level of university students to learn can be caused by their dissatisfaction with certain areas of their lives. The emotions that they experience may prevent them from experiencing the enjoyment of learning, negatively influence attention, concentration, and will, which reflects in their lack of interest and even indifference to learning activities and consequently in deterioration of their learning outcomes. To find out how the students of the VSB – Technical University of Ostrava are satisfied with selected areas of their lives, we presented them with a series of ten consecutive stimuli (one stimulus = a pictogram and a descriptive word) that represented the domains of health – interpersonal relationships – studies – finances – personality characteristics. During the time the student followed the given stimuli, we measured their galvanic skin response (GSR) and in this manner followed the physiological manifestations of their emotions. After completing the measurement, the student completed a non-anonymous questionnaire in which they were required to comment on the quality of the emotion they felt during each stimulus. We compared the obtained data with the study success and verified potential dependencies

Lipoprotein metabolism and LCAT activity in chronic renal failure dogs supplemented with PUFA oils

Due to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to [email protected], referencing the URI of the item.Includes bibliographical references: 44-52.Issued also on microfiche from Lange Micrographics.Serum total cholesterol (TC), lipoprotein cholesterol distribution, and lecithin:cholesterol acyltransferase (LCAT) activities of chronic renal failure dogs were investigated. Control dogs (n = 14) and affected dogs (n = 29) were fed one of three protein/phosphorous restricted diets: low protein canned (LPC), medium protein canned (MPC), or low protein dry (LPD), for 3 to 5 weeks. Basal diets were then supplemented for 6 weeks with menhaden fish oil (MHO) or safflower oil (SFO) in a crossover design which included a 3 week wash-out period. After basal diet acclimation, serum TC increased (paired t-test, p < 0.05) in LPC, MPC, and LPD control groups. At the same time, (X2 lipoprotein cholesterol increased (p < 0.05) in all three control groups. The MPC control dogs also showed an increase (p = 0.01) in cholesterol associated with the (xl fraction after diet acclimation. Among affected dogs, only those receiving the MPC diet showed an elevation (p < 0.01) in serum TC after the basal period. Significant MHO supplement effects included a decrease (p < 0.01) in serum TC in MPC control dogs, and a decrease (p < 0.05) in a2 lipoprotein cholesterol in LPD control dogs. Safflower oil had no significant effect on plasma lipoproteins. No significant differences in serum TC or lipoprotein cholesterol distribution were found between affected and control dogs regardless of basal diet or oil supplementation. Serum LCAT activates were assessed in a subset of MPC dogs; no significant differences between affected and control dogs were revealed. When these two groups were combined, ANOVA revealed an increase in LCAT activities (p < 0.03) after the basal period, and a significant decrease in LCAT activities (p < 0.05) after SFO supplementation. Previously, it was shown that the MPC diet elevated LCAT activities in normal dogs due to its higher fat content; the present group of control and affected dogs confirmed these findings. In the present study, LCAT activates of affected dogs may have been elevated prior to entry because these dogs had been fed renal failure diets which were relatively high in fat before entering the clinical trial

Vysoce kvalitní a snadno regenerovatelný osobní filtr

Proper respiratory tract protection is the key factor to limiting the rate of COVID-19 spread and providing a safe environment for health care workers. Traditional N95 (FFP2) respirators are not easy to regenerate and thus create certain financial and ecological burdens; moreover, their quality may vary significantly. A solution that would overcome these disadvantages is desirable. In this study a commercially available knit polyester fleece fabric was selected as the filter material, and a total of 25 filters of different areas and thicknesses were prepared. Then, the size-resolved filtration efficiency (40-400 nm) and pressure drop were evaluated at a volumetric flow rate of 95 L/min. We showed the excellent synergistic effect of expanding the filtration area and increasing the number of filtering layers on the filtration efficiency; a filter cartridge with 8 layers of knit polyester fabric with a surface area of 900 cm(2) and sized 25 x 14 x 8 cm achieved filtration efficiencies of 98% at 95 L/min and 99.5% at 30 L/min. The assembled filter kit consists of a filter cartridge (14 Pa) carried in a small backpack connected to a half mask with a total pressure drop of 84 Pa at 95 L/min. In addition, it is reusable, and the filter material can be regenerated at least ten times by simple methods, such as boiling. We have demonstrated a novel approach for creating high-quality and easy-to-breathe-through respiratory protective equipment that reduces operating costs and is a green solution because it is easy to regenerate.Správná ochrana dýchacích cest je klíčovým faktorem pro omezení rychlosti šíření COVID-19 a zajištění bezpečného prostředí pro zdravotnické pracovníky. Tradiční respirátory N95 (FFP2) se nedají snadno regenerovat a vytvářejí tak určitou finanční a ekologickou zátěž; navíc se jejich kvalita může výrazně lišit. Žádoucí je řešení, které by tyto nevýhody překonalo. V této studii byla jako filtrační materiál vybrána komerčně dostupná pletená polyesterová fleecová tkanina a bylo připraveno celkem 25 filtrů různých ploch a tlouštěk. Poté byla vyhodnocena účinnost filtrace s rozlišením velikosti (40-400 nm) a pokles tlaku při objemovém průtoku 95 l/min. Prokázali jsme vynikající synergický efekt rozšíření filtrační plochy a zvýšení počtu filtračních vrstev na účinnost filtrace; filtrační patrona s 8 vrstvami pletené polyesterové tkaniny o ploše 900 cm(2) a rozměrech 25 x 14 x 8 cm dosáhla účinnosti filtrace 98 % při 95 l/min a 99,5 % při 30 l/min. Sestavená filtrační sada se skládá z filtrační patrony (14 Pa) nesené v malém batohu spojeném s polomaskou s celkovým tlakovým spádem 84 Pa při 95 l/min. Navíc je opakovaně použitelný a filtrační materiál lze jednoduchými metodami, jako je vaření, nejméně desetkrát regenerovat. Prokázali jsme nový přístup k vytvoření vysoce kvalitních a snadno dýchatelných dýchacích ochranných prostředků, které snižují provozní náklady a jsou ekologickým řešením, protože se snadno regenerují