Cervical Angiomatoid Fibrous Histiocytoma

Background: Angiomatoid fibrous histiocytoma (AFH) is a rare type of sarcoma with low-grade malignancy thatusually occurs in young subjects. AFH is uncommon in the head and neck region.Methods: We describe an exceptional case of localization in the neck. This is the first report of a rare variant of AFHpresenting in a 42-year-old woman. The tumor was situated posterior to the carotid artery adhering to the prevertebralplane and invading the sympathetic cervical chain. In this setting, we decided to perform a surgical exploration withfrozen section biopsy. The frozen section revealed a fusiform tumor proliferation resembling a sarcoma. A FISH studyconcluded on the presence of a EWSR1 22q (22) gene rearrangement. Furthermore, the immunohistochemical studyrevealed anti-EMA positive cells. The final pathological description concluded on the presence of an AFH, which wasexcised by surgery alone.Results: After a 2 year follow-up period, the patient is free of disease. Angiomatoid fibrous histiocytoma (AFH) is arare sarcoma subtype, and mis diagnosis can lead to its over treatment. A precise description of the pathologicalresponse and a multidisciplinary discussion can lead to a correct decision.Conclusion: AFH is a tumor with local evolution, and surgery is the mainstay of its management. Complete localexcision is recommended to hamper local recurrences.

Pseudoaneurisma di origine traumatica localizzato in un seno sfenoidale fratturato

Descriviamo il caso di un pseudoaneurisma di origine traumatica dell’arteria carotide interna destra localizzato all’interno di un seno sfenoidale fratturato che si è sviluppato in un paziente che aveva riportato delle fratture dell’osso frontale e della base cranica che coinvolgevano le pareti del seno sfenoidale e il canale della carotide malgrado l’angio-TC precoce fosse negativa. Il paziente ha presentato due episodi di epistassi ritardata massiva potenzialmente letale prima di essere trattato con successo con tecniche endovascolari utilizzanti spirali metalliche e uno stent non ricoperto. Questo caso sottolinea il fatto che i pazienti con trauma cranico che presentano fratture nel seno sfenoidale con o senza epistassi massiva dovrebbero essere studiati il più presto possibile alla ricerca dello sviluppo di uno pseudoaneurisma postraumatico della carotide interna. Se la prima angio-TC è negativa, un’epistassi ricorrente dovrebbe condurre alla realizzazione di una seconda angio-TC poiché lo pseudoaneurisma richiede tempo per svilupparsi. Un trattamento endovascolare precoce con uno stent non ricoperto può impedire il decesso del paziente

Dosimetric comparison between coplanar and non coplanar field radiotherapy for ethmoid sinus cancer

<p>Abstract</p> <p>Background</p> <p>To compare non coplanar field (NCF) with coplanar field (CF) -intensity-modulated radiotherapy (IMRT) planning for ethmoid cancer.</p> <p>Methods</p> <p>Seven patients treated with NCF IMRT for ethmoid cancer were studied. A CF IMRT optimization was prepared with the same constraints as for the NCF treatment. The maximum point doses (D max) obtained for the different optic pathway structures (OPS) should differ no more than 3% from those achieved with the NCF IMRT plan. The distribution of the dose in the target volume and in the critical structures was compared between the two techniques, as well as the Conformity (CI) and the Homogeneity Indexes (HI) in the target volume.</p> <p>Results</p> <p>We noted no difference between the two techniques in the OPS for the D1, D2, and D5%, in the inner ear and controlateral lens for the average Dmax, in the temporo-mandibular joints for the average mean dose, in the cord and brainstem for the average D1%. The dose-volume histograms were slightly better with the NCF treatment plan for the planning target volume (PTV) with a marginally better HI but no impact on CI. We found a great improvement in the PTV coverage with the CF treatment plan for two patients with T4 tumors.</p> <p>Conclusion</p> <p>IMRT is one of the treatment options for ethmoid cancer. The PTV coverage is optimal without compromising the protection of the OPS. The impact of non coplanar versus coplanar set up is very slight.</p

Surgical Treatment of Carotid Body Paragangliomas: Outcomes and Complications According to the Shamblin Classification

OBJECTIVES: The objective of this study was to review our experience in the surgical management of carotid body paragangliomas and evaluate the outcomes and complications according to the Shamblin classification. METHODS: Thirteen patients who had been diagnosed and surgically treated for carotid body tumors (CBTs) were enrolled in this study. We reviewed patient demographics, radiographic findings, and surgical outcomes collected from medical records. RESULTS: Fifteen CBTs were found in 13 patients and 13 tumors were resected. Selective preoperative tumor embolization was performed on six patients. The median blood loss, operation time, and hospital stay for these patients were not significantly reduced compared to those without embolization. The median tumor size was 2.3 cm in Shamblin I and II and 4 cm in Shamblin III. The median intraoperative blood loss was 280 mL and 700 mL, respectively (P<0.05). Internal carotid artery ligation with reconstruction was accomplished on three patients (23%), and they all belonged to Shamblin III (38%). One Shamblin III patient (8%) developed transient cerebral ischemia, and postoperative stroke with death occurred in another Shamblin III patient. Postoperative permanent cranial nerve deficit occurred in three patients (23%) who were all in Shamblin III (P=0.03). There were no recurrences or delayed complications at the median follow up of 29 months. CONCLUSION: Shamblin III had a high risk of postoperative neurovascular complications. Therefore, early detection and prompt surgical resection of CBTs will decrease surgical morbidity.ope

Supracricoid partial laryngectomy in the management of t3 laryngeal cancer

Objective. To evaluate the oncologic results only in T3 glottic and supraglottic cancers regarding supracricoid partial laryngectomy (SCPL) not requiring total laryngectomy and to assess functional results by self-evaluation by the patient. Study Design. Case series with medical record review. Setting. Single tertiary care center. Subjects and Methods. Thirty-two patients with laryngeal squamous cell carcinoma, previously untreated, who underwent SCPL with cricohyoidopexy or cricohyoidoepiglottopexy were reviewed. Results. At 1, 3, and 5 years, the disease-free survival rates were 96.9%, 89.4%, and 78.2%; overall survival rates were 96.9%, 93.2%, and 87.3%; local control and locoregional control rates were 100%, 96.2%, and 96.2%; and distant metastasis-free survival rates were 100%, 100%, and 88.2%, respectively. Aspiration pneumonia was the most common complication observed. The 3 laryngeal functions (speech, swallowing, and breathing) were spared in 83.9% of patients. Conclusion. Supracricoid partial laryngectomy for selected glottic and supraglottic T3 tumors has excellent oncologic and functional results

Current trends in initial management of hypopharyngeal cancer: The declining use of open surgery

Squamous cell carcinoma of the hypopharynx represents a distinct clinical entity. Most patients present with significant comorbidities and advanced‐stage disease. The overall survival is relatively poor because of high rates of regional and distant metastasis at presentation or early in the course of the disease. A multidisciplinary approach is crucial in the overall management of these patients to achieve the best results and maintain or improve functional results. Traditionally, operable hypopharyngeal cancer has been treated by total (occasionally partial) laryngectomy and partial or circumferential pharyngectomy, followed by reconstruction and postoperative radiotherapy in most cases. Efforts to preserve speech and swallowing function in the surgical treatment of hypopharyngeal (and laryngeal) cancer have resulted in a declining use of total laryngopharyngectomy and improved reconstructive efforts, including microvascular free tissue transfer. There are many surgical, as well as nonsurgical, options available for organ and function preservation, which report equally effective tumor control and survival. The selection of appropriate treatment is of crucial importance in the achievement of optimal results for these patients. In this article, several aspects of surgical and nonsurgical approaches in the treatment of hypopharyngeal cancer are discussed. Future studies must be carefully designed within clearly defined populations and use uniform terminology and standardized functional assessment and declare appropriate patient or disease endpoints. These studies should focus on improvement of resultsx, without increasing patient morbidity. In this respect, technical improvements in radiotherapy such as intensity‐modulated radiotherapy, advances in supportive care, and incorporation of newer systemic agents such as targeted therapy, are relevant developments. © 2010 Wiley Periodicals, Inc. Head Neck, 2012Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90087/1/21613_ftp.pd

Contribution à l'étude de la voix après laryngectomie partielle supracricoïdienne (application au développement de la technique)

AIX-MARSEILLE2-BU Méd/Odontol. (130552103) / SudocPARIS-BIUP (751062107) / SudocSudocFranceF