5 research outputs found
A novel highly selective chemosensor based on curcumin for detection of Cu2+ and its application for bioimaging
Preparation, photoluminescence properties and application for in聽vivo tumor imaging of curcumin derivative-functionalized graphene oxide composite
Micropropagation and protein profile analysis by SDS-PAGE of Gracilaria changii (Rhodophyta, Solieriaceae)
Analytical approaches for proteomics and lipidomics of arsenic in algae
Arsenic (As) is an element with a complex chemistry found in relatively high concentrations in the marine environment. A diverse group of As compounds or As species exist in the marine environment and these are of importance to human health given their potential cytotoxicity. It has been pointed out that marine algae are the origin of such As compounds, since they accumulate arsenate from seawater and metabolize it into several organoarsenic species of both lipophilic and hydrophilic nature. In this chapter, it is intended to discuss lipidomics approaches for identification of the > 70 existing lipophilic arsenic species (arsenolipids) in algae which include arsenic incorporated into phospholipids, hydrocarbons, long-chain alcohols, and polyunsaturated fatty acids. In turn, proteomic analysis will also be presented and discussed in its role, for example, to investigate whether cells show a specific response or survival strategy when under arsenic-induced stress. Research on proteome involvement in stress and tolerance to arsenic offers new tools to understand the associated physiological and biochemical mechanisms connected with different algae responses. Protein biomarkers are also of interest to enable indication of quantitative changes in some physiological parameters as the result of stress or toxicity.N/