110 research outputs found
MOTIVES OF THE EGYPTIAN EDUCATION FUTURE FOR SUSTAINABLE DEVELOPMENT: A COMPARATIVE ANALYSIS BETWEEN 2020 AND 2030
Purpose of the study: The current study aims to identify the engines of the future of Egyptian education to achieve the fourth goal of the United Nations Convention on Sustainable Development.
Methodology: The research followed the analytical method in the comparative analysis of the future of Egyptian education between 2020 and 2030.
Main Findings: The results of the research, in addition to the conclusions of researchers from the literature and previous studies, stressed on the importance of the existence of ten motives for the future of education for sustainable development 2030.
Applications of this study: This research attempts to address this dilemma through the perspectives and engines of education for sustainability. Where teachers can meet the Education for Sustainable Development (ESD) approach to enhance knowledge and positive attitudes towards appropriate action for sustainability in relevant, meaningful, exciting, and creative ways, this research offers experiences that allow pupils to become more connected to nature, develop children's sense of practical orientation that embraces positive attitudes, change behaviour and hope for the child's future.
Novelty/Originality of this study: There is no research or studies that addressed the motives of the Egyptian education future for sustainable development
DEVELOPMENT OF A MICROFLUIDIC GAS GENERATOR FROM AN EFFICIENT FILM-BASED MICROFABRICATION METHOD
poster abstractRecently, tape&film based microfabrication method has been studied for rapid prototyping of microfluidic devices due to its low cost and ease of fabrication [1]. But most of the reported film-based microfluidic devices are simple single-layer patterned 2-dimentional (2D) designs, whose potential applications are limited. In this paper, we present the design, fabrication and testing results of a 3-dimentional (3D) structured microfluidic gas generator prototype. This gas generator is used as an example to introduce our new approach of film-based fabrication method towards lab-use microfluidic research, which usually requires constant change of design and prefers low fabrication cost and short fabrication period. The prototype is a film-based comprehensive microfluidic gas generator which integrates self-circulation, self-regulation, catalytic reaction, and gas/liquid separation. Time and economy efficiency are the biggest merit of this method. The only required facility during the whole process is a digital craft-cutter.
The working principle of the device is illustrated in Fig.1 [2]. The film-based prototype is an alternate version of the silicon-based self-circulating self-regulating gas generator developed by Meng [2]. Fig.2 shows the schematic of the filmbased prototype. It consists of 15 layers of films, tapes, glass slide, tubing connectors, and cube supporting. As shown in Fig.3, the prototype device was obtained by sequentially aligning and stacking multiple layers of patterned films and double-sided Kapton tape. The patterns were obtained by a digital craft-cutter from CAD drawings. The 3D structure was made from both the pattern and the thickness of the layer material, as shown in Fig.4. Besides, functional features can be easily added into the device. For instance, Pt-black was partially sprayed on the tape layer for catalytic reaction using a shadow mask, and nanoporous membrane was cut in the desired shape and stack-placed in position as the gas/liquid separator. The self-circulating and self-regulating functions were achieved by capillary force difference in different channels as shown in Fig.4, which can be achieved by fabricating different channel depths and treating the surface of certain channel into hydrophilic and leave others hydrophobic. The treatment for polystyrene (PS) film was achieved by spraying Lotus Leaf® hydrophilic coating or using oxygen plasma machine [3]. The fabricated device was tested with H2O2 solutions (for O2) and NH3BH3 solutions (for H2) at different concentrations (Fig.5). A pressure difference (1 psi) was applied across the gas/liquid separation membrane to provide better venting. The gas generation profiles are shown in Fig.6 and the summarized characteristics is given in Table 1. The generated gas flow rate is measured by a gas flow meter, and liquid pumping rate measured by monitoring the movement of a liquid/gas meniscus. Fig. 6 shows that higher reactant concentration causes higher gas generation rate. The fluctuation of gas generation rate is due to the pulsatile pumping of this self-pumping mechanism. It is expected that designs with multiple parallel channels can make the gas generation profile smooth due to the interactions among the channels. Detailed characterization results and discussion on reaction kinetics and pumping dynamics in the microfluidic reactor will be reported
Magnetic character of a large continental transform : an aeromagnetic survey of the Dead Sea Fault
Author Posting. © American Geophysical Union, 2007. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Geochemistry Geophysics Geosystems 8 (2007): Q07005, doi:10.1029/2007GC001582.New high-resolution airborne magnetic (HRAM) data along a 120-km-long section of the Dead Sea Transform in southern Jordan and Israel shed light on the shallow structure of the fault zone and on the kinematics of the plate boundary. Despite infrequent seismic activity and only intermittent surface exposure, the fault is delineated clearly on a map of the first vertical derivative of the magnetic intensity, indicating that the source of the magnetic anomaly is shallow. The fault is manifested by a 10–20 nT negative anomaly in areas where the fault cuts through magnetic basement and by a <5 nT positive anomaly in other areas. Modeling suggests that the shallow fault is several hundred meters wide, in agreement with other geophysical and geological observations. A magnetic expression is observed only along the active trace of the fault and may reflect alteration of magnetic minerals due to fault zone processes or groundwater flow. The general lack of surface expression of the fault may reflect the absence of surface rupture during earthquakes. The magnetic data also indicate that unlike the San Andreas Fault, the location of this part of the plate boundary was stable throughout its history. Magnetic anomalies also support a total left-lateral offset of 105–110 km along the plate boundary, as suggested by others. Finally, despite previous suggestions of transtensional motion along the Dead Sea Transform, we did not identify any igneous intrusions related to the activity of this fault segment.The project was funded by U.S.-AID Middle Eastern
Regional Cooperation grant TA-MOU-01-M21-012
Plate osteosynthesis versus hemiarthroplasty in proximal humerus fractures – Does routine screening of systemic inflammatory biomarkers makes sense?
Current state of fine mineral tailings treatment: A critical review on theory and practice
The mining industry produces fluid fine mineral tailings on the order of millions of tonnes each year, with billions of tonnes already stored globally. This trend is expected to escalate as demand for mineral products continues to grow with increasingly lower grade ores being more commonly exploited by hydrometallurgy. Ubiquitous presence and enrichment of fine solids such as silt and clays in fluid fine mineral tailings prevent efficient solid-liquid separation and timely re-use of valuable process water. Long-term storage of such fluid waste materials not only incurs a huge operating cost, but also creates substantial environmental liabilities of tailings ponds for mining operators. This review broadly examines current theoretical understandings and prevalent industrial practices on treating fine mineral tailings for greater water recovery and reduced environmental footprint of mining operations
Cross-protection induced by highly conserved human B, CD4+, and CD8+ T-cell epitopes-based vaccine against severe infection, disease, and death caused by multiple SARS-CoV-2 variants of concern
BackgroundThe coronavirus disease 2019 (COVID-19) pandemic has created one of the largest global health crises in almost a century. Although the current rate of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections has decreased significantly, the long-term outlook of COVID-19 remains a serious cause of morbidity and mortality worldwide, with the mortality rate still substantially surpassing even that recorded for influenza viruses. The continued emergence of SARS-CoV-2 variants of concern (VOCs), including multiple heavily mutated Omicron sub-variants, has prolonged the COVID-19 pandemic and underscores the urgent need for a next-generation vaccine that will protect from multiple SARS-CoV-2 VOCs.MethodsWe designed a multi-epitope-based coronavirus vaccine that incorporated B, CD4+, and CD8+ T- cell epitopes conserved among all known SARS-CoV-2 VOCs and selectively recognized by CD8+ and CD4+ T-cells from asymptomatic COVID-19 patients irrespective of VOC infection. The safety, immunogenicity, and cross-protective immunity of this pan-variant SARS-CoV-2 vaccine were studied against six VOCs using an innovative triple transgenic h-ACE-2-HLA-A2/DR mouse model.ResultsThe pan-variant SARS-CoV-2 vaccine (i) is safe , (ii) induces high frequencies of lung-resident functional CD8+ and CD4+ TEM and TRM cells , and (iii) provides robust protection against morbidity and virus replication. COVID-19-related lung pathology and death were caused by six SARS-CoV-2 VOCs: Alpha (B.1.1.7), Beta (B.1.351), Gamma or P1 (B.1.1.28.1), Delta (lineage B.1.617.2), and Omicron (B.1.1.529).ConclusionA multi-epitope pan-variant SARS-CoV-2 vaccine bearing conserved human B- and T- cell epitopes from structural and non-structural SARS-CoV-2 antigens induced cross-protective immunity that facilitated virus clearance, and reduced morbidity, COVID-19-related lung pathology, and death caused by multiple SARS-CoV-2 VOCs
Labour Migration from the Eastern Partnership Countries: Evolution and Policy Options for Better Outcomes
This study is part of the project entitled Costs and Benefits of Labour Mobility between the EU and the Eastern Partnership Countries for the European Commission1. The study was written by Luca Barbone (CASE) Mikhail Bonch- Osmolovskiy (CASE) and Matthias Luecke (Kiel). It is based on the six country studies for the Eastern Partnership countries commissioned under this project and prepared by Mihran Galstyan and Gagik Makaryan (Armenia), Azer Allahveranov and Emin Huseynov (Azerbaijan), Aleksander Chubrik and Aliaksei Kazlou (Belarus), Lasha Labadze and Mirjan Tukhashvili (Georgia), Vasile Cantarji and Georgeta Mincu (Moldova), Tom Coupé and Hanna Vakhitova (Ukraine). The authors would like to thank for their comments and suggestions Kathryn Anderson, Martin Kahanec, Costanza Biavaschi, Lucia Kurekova, Monica Bucurenciu, Borbala Szegeli, Giovanni Cremonini and Ummuhan Bardak, as well as the dbaretailed review provided by IOM. The views in this study are those of the authors' only, and should not be interpreted as representing the official position of the European Commission and its institutions
Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries
Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P < 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely
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