The S2N2 metallicity calibrator and the abundance gradient of M 33

We introduce the log(Ha/[SII]6717+6731) vs. log(Ha/[NII]6583) (S2N2) diagnostic diagram as metallicity and ionisation parameter indicator for HII regions in external galaxies. The location of HII regions in the S2N2 diagram was studied both empirically and theoretically. We found that, for a wide range of metallicities, the S2N2 diagram gives single valued results in the metallicity-ionisation parameter plane. We demonstrate that the S2N2 diagram is a powerful tool to estimate metallicities of high-redshift (z ~ 2) HII galaxies. Finally, we derive the metallicity for 76 HII regions in M33 from the S2N2 diagram and calculate an O/H abundance gradient for this galaxy of -0.05 (+-0.01) dex kpc^-1.Comment: 10 pages, 3 figures and 2 tables. Accepted for publication in MNRA

RF and IF mixer optimum matching impedances extracted by large-signal vectorial measurements

This paper introduces a new technique that allows us to measure the admittance conversion matrix of a two-port device,using a Nonlinear Vector Network Analyzer.This method is applied to extract the conversion matrix of a 0.2 µµµµm pHEMT,driven by a 4.8 GHz pump signal,at different power levels,using an intermediate frequency of 600 MHz.The issue on data inconsistency due to phase randomization among different measurements is discussed and a proper pre- processing algorithm is proposed to fix the problem. The output of this work consists of a comprehensive experimental evaluation of up-and down-conversion maximum gain,stability,and optimal RF and IF impedances

Weathering Effects on Engineering Geological Properties of Trachydacitic Volcanic Rocks from the Monte Amiata (Southern Tuscany, Italy)

Variability in lithology and weathering degree affects physical and mechanical properties of rocks. In this study, we investigated the relationships between weathering degree and engineering geological properties of trachydacitic volcanic rocks from Monte Amiata (central Italy) by coupling field and laboratory analyses. We collected in situ Schmidt hammer tests in the field. We evaluated weathering quantifying the percentage of secondary minerals through thermal analysis in the laboratory. We also determined dry density (rd), specific gravity of solids (Gs), porosity (n) and two-dimensional (2D) porosity as resulted from scanning electron microscopy investigations. The results of our study indicate a negative linear correlation between Schmidt hammer rebound values and secondary mineral percentage. This correlation provides a tool to quantitatively estimate the deterioration of rock uniaxial compressive strength (UCS) as weathering increases. Moreover, thermal analysis turned out to be a quantitative and reproducible method to evaluate weathering degree of magmatic rocks

HII regions within a compact high velocity cloud. A nearly star-less dwarf galaxy?

Within the SECCO survey we identified a candidate stellar counterpart to the Ultra Compact High Velocity Cloud (UCHVC) HVC274.68+74.70-123, that was suggested by Adams et al. (2013) as a possible mini-halo within the Local Group of galaxies. The spectroscopic follow-up of the brightest sources within the candidate reveals the presence of two HII regions whose radial velocity is compatible with physical association with the UVHVC. The available data does not allow us to give a definite answer on the nature of the newly identified system. A few alternative hypotheses are discussed. However, the most likely possibility is that we have found a new faint dwarf galaxy residing in the Virgo cluster of galaxies, which we name SECCO-1. Independently of its actual distance, SECCO-1 displays a ratio of neutral hydrogen mass to V luminosity of M_{HI}/L_V>= 20, by far the largest among local dwarfs. Hence, it appears as a nearly star-less galaxy and it may be an example of the missing links between normal dwarfs and the dark mini halos that are predicted to exist in large numbers according to the currently accepted cosmological model.Comment: Accepted for publication in ApJ Letters. Pdflatex, emulateapj.cls. 6 pages, 3 figures, 2 table

A catalog of planetary nebula candidates and HII regions in NGC 3109

Images obtained with the ESO VLT and FORS1 in [O III] 5007 on- and off-band as well as r_Gunn filters are analyzed to search for Planetary Nebula (PN) candidates in the dwarf irregular NGC 3109. In the continuum-subtracted [O III] 5007 on-band images, a large number of emission-line regions were detected. We describe the criteria employed in order to distinguish PN candidates from compact HII regions, finding that the sizes and the properties of the ionizing stars are the most unambiguous discriminators for separating the two classes. Based upon these criteria, we have found 20 PN candidates for which we present coordinates, nebular [O III] fluxes, and stellar magnitudes. The cumulative luminosity function for these PNe is discussed. A catalog of HII regions listing coordinates, nebular [O III] fluxes, stellar magnitudes and other characteristics is also presented. We find that HII regions are rather concentrated towards the disk of the galaxy, while PNe are found also above and below this structure, consistent with their belonging to an older stellar population.Comment: 8 pages, including 4 figures and 3 tables. Accepted in A&A. Replaced with the final versio

Global access to affordable direct oral anticoagulants

Poor control of cardiovascular disease accounts for a substantial proportion of the disease burden in developing countries, but often essential anticoagulant medicines for preventing strokes and embolisms are not widely available. In 2019, direct oral anticoagulants were added to the World Health Organization's WHO Model list of essential medicines. The aims of this paper are to summarize the benefits of direct oral anticoagulants for patients with cardiovascular disease and to discuss ways of increasing their usage internationally. Although the cost of direct oral anticoagulants has provoked debate, the affordability of introducing these drugs into clinical practice could be increased by: price negotiation; pooled procurement; competitive tendering; the use of patent pools; and expanded use of generics. In 2017, only 14 of 137 countries that had adopted national essential medicines lists included a direct oral anticoagulant on their lists. This number could increase rapidly if problems with availability and affordability can be tackled. Once the types of patient likely to benefit from direct oral anticoagulants have been clearly defined in clinical practice guidelines, coverage can be more accurately determined and associated costs can be better managed. Government action is required to ensure that direct oral anticoagulants are covered by national budgets because the absence of reimbursement remains an impediment to achieving universal coverage. Tackling cardiovascular disease with the aid of direct oral anticoagulants is an essential component of efforts to achieve the World Health Organization's target of reducing premature deaths due to noncommunicable disease by 25% by 2025

Discovery of true, likely and possible symbiotic stars in the dwarf spheroidal NGC 205

In this paper we discuss the photometric and spectroscopic observations of newly discovered (symbiotic) systems in the dwarf spheroidal galaxy NGC 205. The Gemini Multi-Object Spectrograph on-off band [O III] 5007 A emission imaging highlighted several [O III] line emitters, for which optical spectra were then obtained (Gon\c{c}alves et al. 2014). The detailed study of the spectra of three objects allow us to identify them as true, likely and possible symbiotic systems (SySts), the first ones discovered in this galaxy. SySt-1 is unambiguously classified as a symbiotic star, because of the presence of unique emission lines which belong only to symbiotic spectra, the well known O VI Raman scattered lines. SySt-2 is only possibly a SySt because the Ne VII Raman scattered line at 4881 A, recently identified in a well studied Galactic symbiotic as another very conspicuous property of symbiotic, could as well be identified as N III or [Fe III]. Finally, SySt-3 is likely a symbiotic binary because in the red part of the spectrum it shows the continuum of a late giant, and forbidden lines of moderate- to high-ionization, like [Fe v] 4180 A. The main source for skepticism on the symbiotic nature of the latter systems is their location in the PN region in the [O III] 4363/H\gamma\ vs [O III] 5007/H\beta\ diagnostic diagram (Gutierrez-Moreno et al. 1995). It is worth mentioning that at least another two confirmed symbiotics, one of the Local Group dwarf spheroidal IC 10 and the other of the Galaxy, are also misplaced in this diagram.Comment: 8 pages, 5 figures, accepted for publication in MNRAS

Planetary nebulae in M33: probes of AGB nucleosynthesis and ISM abundances

We have obtained deep optical spectrophotometry of 16 planetary nebulae in M33, mostly located in the central two kpc of the galaxy, with the Subaru and Keck telescopes. We have derived electron temperatures and chemical abundances from the detection of the [OIII]4363 line for the whole sample. We have found one object with an extreme nitrogen abundance, 12+log(N/H)=9.20, accompanied by a large helium content. After combining our data with those available in the literature for PNe and HII regions, we have examined the behavior of nitrogen, neon, oxygen and argon in relation to each other, and as a function of galactocentric distance. We confirm the good correlation between Ne/H and O/H for PNe in M33. Ar/H is also found to correlate with O/H. This strengthens the idea that at the metallicity of the bright PNe analyzed in M33, which is similar to that found in the LMC, these elements have not been significantly modified during the dredge-up processes that take place during the AGB phase of their progenitor stars. We find no significant oxygen abundance offset between PNe and HII regions at any given galactocentric distance, despite the fact that these objects represent different age groups in the evolution of the galaxy. Combining the results from PNe and HII regions, we obtain a representative slope of the ISM alpha-element (O, Ar, Ne) abundance gradient in M33 of -0.025 +/- 0.006 dex/kpc. Both PNe and HII regions display a large abundance dispersion at any given distance from the galactic center. We find that the N/O ratio in PNe is enhanced, relative to the HII regions, by approximately 0.8 dex.Comment: 21 pages, 20 figures. Accepted for publication in MNRA

Gas accretion as the origin of chemical abundance gradients in distant galaxies

It has recently been suggested that galaxies in the early Universe can grow through the accretion of cold gas, and that this may have been the main driver of star formation and stellar mass growth. Because the cold gas is essentially primordial, it has a very low abundance of elements heavier than helium (metallicity). As it is funneled to the centre of a galaxy, it will lead the central gas having an overall lower metallicity than gas further from the centre, because the gas further out has been enriched by supernovae and stellar winds, and not diluted by the primordial gas. Here we report chemical abundances across three rotationally-supported star-forming galaxies at z~3, only 2 Gyr after the Big Bang. We find an 'inverse' gradient, with the central, star forming regions having a lower metallicity than less active ones, opposite to what is seen in local galaxies. We conclude that the central gas has been diluted by the accretion of primordial gas, as predicted by 'cold flow' models.Comment: To Appear in Nature Oct 14, 2010; Supplementary Information included her