4 research outputs found

    Video Filtering Using Separable Four-Dimensional Nonlocal Spatiotemporal Transforms

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    The large number of practical application involving digital videos has motivated a significant interest in restoration or enhancement solutions to improve the visual quality under the presence of noise. We propose a powerful video denoising algorithm that exploits temporal and spatial redundancy characterizing natural video sequences to reduce the effects of noise. The algorithm implements the paradigm of nonlocal grouping and collaborative filtering, where a four-dimensional transform- domain representation is leveraged to enforce sparsity and thus regularize the data. Moreover we present an extension of our algorithm that can be effectively used as a deblocking and deringing filter to reduce the artifacts introduced by most of the popular video compression techniques. Our algorithm, termed V-BM4D, at first constructs three-dimensional volumes, by tracking blocks along trajectories defined by the motion vectors, and then groups together mutually similar volumes by stacking them along an additional fourth dimension. Each group is transformed through a decorrelating four-dimensional separable transform, and then it is collaboratively filtered by coeffcients shrinkage. The effectiveness of shrinkage is due to the sparse representation of the transformed group. Sparsity is achieved because of different type of correlation among the groups: local correlation along the two dimensions of the blocks, temporal correlation along the motion trajectories, and nonlocal spatial correlation along the fourth dimension. As a conclusive step, the different estimates of the filtered groups are adaptively aggregated and subsequently returned to their original position, to produce a final estimate of the original video. The proposed filtering procedure leads to excellent results in both objective and subjective visual quality, since in the restored video sequences the effect of the noise or of the compression artifacts is noticeably reduced, while the significant features are preserved. As demonstrated by experimental results, V-BM4D outperforms the state of the art in video denoising. /Kir1

    Video Filtering Using Separable Four-Dimensional Nonlocal Spatiotemporal Transforms

    Get PDF
    The large number of practical application involving digital videos has motivated a significant interest in restoration or enhancement solutions to improve the visual quality under the presence of noise. We propose a powerful video denoising algorithm that exploits temporal and spatial redundancy characterizing natural video sequences to reduce the effects of noise. The algorithm implements the paradigm of nonlocal grouping and collaborative filtering, where a four-dimensional transform- domain representation is leveraged to enforce sparsity and thus regularize the data. Moreover we present an extension of our algorithm that can be effectively used as a deblocking and deringing filter to reduce the artifacts introduced by most of the popular video compression techniques. Our algorithm, termed V-BM4D, at first constructs three-dimensional volumes, by tracking blocks along trajectories defined by the motion vectors, and then groups together mutually similar volumes by stacking them along an additional fourth dimension. Each group is transformed through a decorrelating four-dimensional separable transform, and then it is collaboratively filtered by coeffcients shrinkage. The effectiveness of shrinkage is due to the sparse representation of the transformed group. Sparsity is achieved because of different type of correlation among the groups: local correlation along the two dimensions of the blocks, temporal correlation along the motion trajectories, and nonlocal spatial correlation along the fourth dimension. As a conclusive step, the different estimates of the filtered groups are adaptively aggregated and subsequently returned to their original position, to produce a final estimate of the original video. The proposed filtering procedure leads to excellent results in both objective and subjective visual quality, since in the restored video sequences the effect of the noise or of the compression artifacts is noticeably reduced, while the significant features are preserved. As demonstrated by experimental results, V-BM4D outperforms the state of the art in video denoising. /Kir1

    Correction to: Tocilizumab for patients with COVID-19 pneumonia. The single-arm TOCIVID-19 prospective trial

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    A Survey of Empirical Results on Program Slicing

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    International audienceBACKGROUND:Patients with peripheral artery disease have an increased risk of cardiovascular morbidity and mortality. Antiplatelet agents are widely used to reduce these complications.METHODS:This was a multicentre, double-blind, randomised placebo-controlled trial for which patients were recruited at 602 hospitals, clinics, or community practices from 33 countries across six continents. Eligible patients had a history of peripheral artery disease of the lower extremities (previous peripheral bypass surgery or angioplasty, limb or foot amputation, intermittent claudication with objective evidence of peripheral artery disease), of the carotid arteries (previous carotid artery revascularisation or asymptomatic carotid artery stenosis of at least 50%), or coronary artery disease with an ankle-brachial index of less than 0·90. After a 30-day run-in period, patients were randomly assigned (1:1:1) to receive oral rivaroxaban (2·5 mg twice a day) plus aspirin (100 mg once a day), rivaroxaban twice a day (5 mg with aspirin placebo once a day), or to aspirin once a day (100 mg and rivaroxaban placebo twice a day). Randomisation was computer generated. Each treatment group was double dummy, and the patient, investigators, and central study staff were masked to treatment allocation. The primary outcome was cardiovascular death, myocardial infarction or stroke; the primary peripheral artery disease outcome was major adverse limb events including major amputation. This trial is registered with ClinicalTrials.gov, number NCT01776424, and is closed to new participants.FINDINGS:Between March 12, 2013, and May 10, 2016, we enrolled 7470 patients with peripheral artery disease from 558 centres. The combination of rivaroxaban plus aspirin compared with aspirin alone reduced the composite endpoint of cardiovascular death, myocardial infarction, or stroke (126 [5%] of 2492 vs 174 [7%] of 2504; hazard ratio [HR] 0·72, 95% CI 0·57-0·90, p=0·0047), and major adverse limb events including major amputation (32 [1%] vs 60 [2%]; HR 0·54 95% CI 0·35-0·82, p=0·0037). Rivaroxaban 5 mg twice a day compared with aspirin alone did not significantly reduce the composite endpoint (149 [6%] of 2474 vs 174 [7%] of 2504; HR 0·86, 95% CI 0·69-1·08, p=0·19), but reduced major adverse limb events including major amputation (40 [2%] vs 60 [2%]; HR 0·67, 95% CI 0·45-1·00, p=0·05). The median duration of treatment was 21 months. The use of the rivaroxaban plus aspirin combination increased major bleeding compared with the aspirin alone group (77 [3%] of 2492 vs 48 [2%] of 2504; HR 1·61, 95% CI 1·12-2·31, p=0·0089), which was mainly gastrointestinal. Similarly, major bleeding occurred in 79 (3%) of 2474 patients with rivaroxaban 5 mg, and in 48 (2%) of 2504 in the aspirin alone group (HR 1·68, 95% CI 1·17-2·40; p=0·0043).INTERPRETATION:Low-dose rivaroxaban taken twice a day plus aspirin once a day reduced major adverse cardiovascular and limb events when compared with aspirin alone. Although major bleeding was increased, fatal or critical organ bleeding was not. This combination therapy represents an important advance in the management of patients with peripheral artery disease. Rivaroxaban alone did not significantly reduce major adverse cardiovascular events compared with asprin alone, but reduced major adverse limb events and increased major bleeding
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