96,464 research outputs found

    Breast Cancer in Art Painting

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    Breast cancer is an emotive cancer. It is a disease that affects a visible sexual organ and it is the commonest single cause of death of women between 40 and 60 years of age. Nevertheless, this type of cancer was infrequently depicted in art paintings. In this article the themes from the breast cancer in famous art paintings are discussed

    The basic biology of erbB-2 and its participation in colorectal cancers

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    ErbB-2 is one of Tour cell surface growth factor receptors involved in transmission of signals controlling normal cell growth and differentiation. A range of growth factors serve as ligands, but none is specific for the ErbB-2 receptor. Ligand binding to ErbB-1, ErbB-3 and ErbB-4 induces rapid receptor dimerization, with a marked preference for ErbB-2 as a dimer partner. When ErbB-2 is overexpressed multiple ErbB-2 heterodimers are formed and cell signalling is stronger, resulting in enhanced responsiveness to growth factors and malignant growth. This explains why ErbB-2 overexpression is an indicator of poor prognosis in colorectal cancers and may be predictive of response to treatment. ErbB-2 is a highly specific and promising target for new colon cancer treatments.Zadanie pt. „Digitalizacja i udostępnienie w Cyfrowym Repozytorium Uniwersytetu Łódzkiego kolekcji czasopism naukowych wydawanych przez Uniwersytet Łódzki” nr 885/P-DUN/2014 dofinansowane zostało ze środków MNiSW w ramach działalności upowszechniającej naukę

    An algebraic model for rational SO(3)-spectra

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    Greenlees established an equivalence of categories between the homotopy category of rational SO(3)-spectra and the derived category DA(SO(3)) of a certain abelian category. In this paper we lift this equivalence of homotopy categories to the level of Quillen equivalences of model categories. Methods used in this paper provide the first step towards obtaining an algebraic model for the toral part of rational G-spectra, for any compact Lie group G

    A Trip to the Amazon Forest

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    Postcard from Magdalena McGuire, during the Linfield College Semester Abroad Program at the Universidad San Francisco de Quito in Ecuado

    István, a király: Rock-Opera As an Expression of Hungarian National Identity

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    The movie Istvàn, a kiràly presents themes which are not only universal, but also crucial for the process of building Hungarian national identity, such as the myth of origin, the insoluble conflict between the past and present, Christianity, and the valour of the fight for freedom and respect for tradition. These motifs make Istvàn, a kiràly worth watching not only for Hungarians, but also for all non-Hungarians who desire to understand the culture of Hungary. For them, Istvàn, a kiràly will be an invaluable insight into the Hungarian mind.This book was financially supported by the National Programme for the Development of Humanities: project “Cinema: Intercultural Perspective. Western-European Cinema in Poland, Polish Cinema in Western Europe. Mutual Perception of Film Cultures (1918–1939)”

    Post-error brain activity correlates with incidental memory for negative words

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    The present study had three main objectives. First, we aimed to evaluate whether short-duration affective states induced by negative and positive words can lead to increased error-monitoring activity relative to a neutral task condition. Second, we intended to determine whether such an enhancement is limited to words of specific valence or is a general response to arousing material. Third, we wanted to assess whether post-error brain activity is associated with incidental memory for negative and/or positive words. Participants performed an emotional stop-signal task that required response inhibition to negative, positive or neutral nouns while EEG was recorded. Immediately after the completion of the task, they were instructed to recall as many of the presented words as they could in an unexpected free recall test. We observed significantly greater brain activity in the error-positivity (Pe) time window in both negative and positive trials. The error-related negativity amplitudes were comparable in both the neutral and emotional arousing trials, regardless of their valence. Regarding behavior, increased processing of emotional words was reflected in better incidental recall. Importantly, the memory performance for negative words was positively correlated with the Pe amplitude, particularly in the negative condition. The source localization analysis revealed that the subsequent memory recall for negative words was associated with widespread bilateral brain activity in the dorsal anterior cingulate cortex and in the medial frontal gyrus, which was registered in the Pe time window during negative trials. The present study has several important conclusions. First, it indicates that the emotional enhancement of error monitoring, as reflected by the Pe amplitude, may be induced by stimuli with symbolic, ontogenetically learned emotional significance. Second, it indicates that the emotion-related enhancement of the Pe occurs across both negative and positive conditions, thus it is preferentially driven by the arousal content of an affective stimuli. Third, our findings suggest that enhanced error monitoring and facilitated recall of negative words may both reflect responsivity to negative events. More speculatively, they can also indicate that post-error activity of the medial prefrontal cortex may selectively support encoding for negative stimuli and contribute to their privileged access to memory

    Single-phase feeding and compensatory growth in growing and finishing pigs (OK-Net Ecofeed Practice Abstract)

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    • Limit the supply of essential amino acids during early growth and utilise the pigs’ capacity to fully compensate for the restriction by increased protein retention and faster growth during later growth phases. • Crude protein and lysine contents can be substantially reduced, below common standards (i.e. crude protein to 16.5% and digestible lysine between 0.70-0.80 g standardised ileal digestible (SID) lysine/MJ NE), in well-balanced diets. • A reduction in crude protein content, from 15.5 to 14.5 g SID/g SID lysine can lower the nitrogen output by approximately 10%. • Formulate diets on a digestible amino acid basis rather than on a total amino acid or crude protein basis. • High-quality protein feed ingredients such as faba beans, peas, oil seed-, dairy- and cereal-based by-products, aquatic resources, etc., or a combination of them, can be used. • At the pig level, this practice can reduce soya bean cake utilisation (14%) and increase pea utilisation (22%). • Careful follow-up of the pigs' feed consumption, growth and health status is recommended

    Introduction

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    Zadanie „Stworzenie anglojęzycznych wersji wydawanych publikacji” finansowane w ramach umowy nr 948/P-DUN/2016 ze środków Ministra Nauki i Szkolnictwa Wyższego przeznaczonych na działalność upowszechniającą naukę
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