75 research outputs found

    O direito/ dever de expressão/ informação face ao direito à privacidade

    Get PDF
    RESUMO: O avanço da tecnologia e a velocidade da informação com o crescimento da participação dos indivíduos em rede sociais. O direito brasileiro tem por intuito proteger o direito da personalidade, todavia, a depender do exame etimológico da palavra personalidade pode-se chegar a conceitos distintos. Em que pese, pretende-se aprofundar em relação à imprensa como meio facilitador para adentrar na vida privada do indivíduo, o direito à informação se contrapõe diretamente com o direito à privacidade, e também o direito à expressão. No entanto, tem-se em vista que a depender da maneira em que se divulga a informação (imagens, vídeos, nomes) existe a possibilidade de configurar o vilipêndio de cadáver, por ferir diretamente os direitos da personalidade, direitos estes intrínsecos ao ser humano, ressaltando que deve ser analisado o caso sub judice para certificar o enquadramento do devido artigo penal

    O DIREITO/ DEVER DE EXPRESSÃO/ INFORMAÇÃO FACE AO DIREITO À PRIVACIDADE: UM OLHAR CRÍTICO SOBRE A EXPOSIÇÃO DO VILIPÊNDIO A CADÁVER

    Get PDF
    RESUMO: O avanço da tecnologia e a velocidade da informação com o crescimento da participação dos indivíduos em rede sociais. O direito brasileiro tem por intuito proteger o direito da personalidade, todavia, a depender do exame etimológico da palavra personalidade pode-se chegar a conceitos distintos. Em que pese, pretende-se aprofundar em relação à imprensa como meio facilitador para adentrar na vida privada do indivíduo, o direito à informação se contrapõe diretamente com o direito à privacidade, e também o direito à expressão. No entanto, tem-se em vista que a depender da maneira em que se divulga a informação (imagens, vídeos, nomes) existe a possibilidade de configurar o vilipêndio de cadáver, por ferir diretamente os direitos da personalidade, direitos estes intrínsecos ao ser humano, ressaltando que deve ser analisado o caso sub judice para certificar o enquadramento do devido artigo penal

    A Status Assessment of Perkinsiosis, Bonamiosis, and Mateiliosis in Commercial Marine Bivalves from Southern Brazil

    Get PDF
    14 páginas, 1 figura, 3 tablas.-- Simone Sühnel ... et al.The protozoans Perkinsus marinus, Perkinsus olseni, Bonamia ostreae, Bonamia exitiosa, and Marteilia refringens are responsible for some of the most detrimental diseases in the production of cultivated shellfish worldwide and are classified as notifiable diseases by the World Organization for Animal Health (OIE). This study examined the general health status of wild and cultured bivalves from southern Brazil and included diagnostic tests for the presence of Perkinsus sp., Bonamia sp., andMarteilia sp. Cultured bivalves included the mangrove oyster Crassostrea gasar (syn. Crassostrea brasiliana), the brown mussel Perna perna, the lion's paw scallop Nodipecten nodosus, andwing pearl oyster Pteria hirundo. Themangrove oyster Crassostrea rhizophorae and the carib pointed venus clam Anomalocardia brasiliana (syn. Anomalocardia flexuosa) were collected from wild populations. A variety of parasitic or commensal organisms were detected by histology including Ancistrocoma-like and Spenophrya-like organisms; Bucephalus genus, Nematopsis sp., Steinhausia sp., and Tylocephalum sp.; unidentified trematode; unknown protozoan and metazoans; and an amoeba parasite. Hemocytic infiltration was most commonly associated with parasitized animals. Histological, culture and molecular diagnostic tests did not find any evidence of the presence of OIE-listed pathogens or related species in this study. Although the current survey did not identify any pathogens or diseases of concern, it provides baseline health assessment data for these species against which any future disease developments or significant changes in population health can be compared. These data are also valuable with respect to the development and implementation of public policies related to aquatic animal healthWe would like to thank to the Ministry of Fisheries and Aquaculture, Brazil, for the research support provided to the Fundaçao de Amparo à Pesquisa do Estado de Santa Catarina (FAPESC), Brazil; the National Council of Technological and ScientificDevelopment, Brazil (CNPq-558222/2008-0), for supporting themacro- andmicroscopical analysis and for providing a grant (CNPq-301072/2007-8); the Coordenaçao de Aperfeiçoamento de Pessoal de Nivel Superior (CAPES), Brazil, for post-doctoral scholarship support for SS; the Pacific Biologic Station and Vancouver Island University (VIU) in Canada for supporting the molecular studiesPeer reviewe

    Distensibility and Strength of the Pelvic Floor Muscles of Women in the Third Trimester of Pregnancy

    Get PDF
    Objective. the objective of this study was to compare the role of the pelvic floor muscles between nulliparous and multiparous women in the third trimester of pregnancy, by analyzing the relationship between electrical activity (surface electromyography-EMG), vaginal palpation (modified Oxford scale), and perineal distensibility (Epi-no). Methods. This was an observational cross-sectional study on a sample of 60 healthy pregnant women with no cervical dilation, single fetus, gestational age between 35 and 40 weeks, and maternal age ranging from 15 to 40 years. the methods used were bidigital palpation (modified Oxford scale, graded 05), surface EMG(electrical activity during maximal voluntary contraction), and perineal distensibility (Epi-no device). the Pearson correlation coefficient (r) was used to analyze the Epi-no values and the surface EMG findings. the Kruskal-Wallis test was used to compare the median values from surface EMG and Epi-no, using the modified Oxford scale scores. Results. Among the 60 patients included in this study, 30 were nulliparous and 30 multiparous. the average maternal age and gestational age were 26.06 (+/- 5.58) and 36.56 (+/- 1.23), respectively. It was observed that nulliparous women had both higher perineal muscle strength (2.53 +/- 0.57 versus 2.06 +/- 0.64;P = 0.005) and higher electrical activity (45.35 +/- 12.24.. V versus 35.79 +/- 11.66 mu V;P = 0.003), while among the multiparous women, distensibility was higher (19.39 +/- 1.92 versus 18.05 +/- 2.14;P = 0.013). We observed that there was no correlation between perineal distensibility and electrical activity during maximal voluntary contraction(r = -0.193;p - 0.140). However, we found a positive relationship between vaginal palpation and surface electromyography (P = 0.008), but none between Epi-no values (P = 0.785). Conclusion. the electrical activity and muscle strength of the pelvic floor muscles of the multiparous women were damaged, in relation to the nulliparous women, while the perineal distensibility was lower in the latter group. There was a positive relationship between surface EMG and the modified Oxford scale.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Fed Univ São Paulo UNIFESP, Dept Obstet, BR-05303000 Vila Leopoldina, SP, BrazilUniv Fed Uberlandia, Fac Phys Educ & Physiotherapy, BR-38400 Uberlandia, MG, BrazilFed Univ São Paulo UNIFESP, Dept Obstet, BR-05303000 Vila Leopoldina, SP, BrazilFAPESP: 2011/18731-6Web of Scienc

    Engineering single-atom Fe-N active sites on hollow carbon spheres for oxygen reduction reaction

    Get PDF
    Seeking alternatives to noble metals-based electrocatalysts for oxygen reduction reaction (ORR), hollow carbon spheres (CSs) were finely tuned with stable single-atom Fe-N species through a synthesis methodology requiring only earth-abundant metal precursors. CSs with different sizes were synthesized by sol-gel polycondensation of resorcinol with formaldehyde over silica nanoparticles, followed by thermal annealing and silica etching. A catalyst screening revealed the positive impact of both the hollow core and structural defects of the CSs for ORR. Single-atom Fe-N active sites were introduced on the best performing CSs through simultaneous incorporation of iron and nitrogen precursors, and glucose. A significant enhancement in ORR activity was observed despite the small iron load introduced (0.12 wt%). ORR performance indicators, advanced characterization, and molecular simulation studies revealed nitrogen's crucial role in anchoring individual iron atoms and modulating the charge density nearby the active sites (increase of 80 mV in the half-wave potential). Adding glucose as a chelating agent enhances the metal-heteroatom coordination and subsequent dispersion of iron, accounting for an increase of 20 mV in the half-wave potential, an average of electrons transferred as high as 3.9 (at 0.4 V vs. RHE), and higher stability (99%) than that of a platinum-based (20 wt%) electrocatalyst (92%).11 página

    Experiência de uma consulta de cardio-oncologia num hospital universitário terciário em Portugal: estudo observacional

    Get PDF
    © 2022 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espa ̃na, S.L.U. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)Introduction: Heart disease and cancer are the two leading causes of morbidity and mortality worldwide. Advances in cancer screening and management have led to longer survival and better quality of life. Despite this progress, many cancer patients experience cardiovascular complications during and after cancer treatment. This study describes the experience of a cardio-oncology program at tertiary academic hospital. Methods: In this retrospective observational study, cancer patients referred to the CHULN cardio-oncology consultation (COC) between January 2016 and December of 2019 were included. Data collected included: patient demographics, cancer type, reason for referral, cardiovascular risk factors, cardiac and oncologic treatments and clinical outcomes. Results: A total of 520 patients (mean age: 65 ± 14 years; 65% women) were referred to the COC. The main reasons for referral were suspected heart failure (26%), pre-high risk chemotherapy assessment (20%) and decreased LVEF (15%). Pre-existing cardiovascular risk factors were common (79%) and 309 (59%) were taking cardiac medications. The most common type of malignancy was breast cancer (216, 41%) followed by gastrointestinal (139, 27%). More than half received anthracycline-based regimens (303, 58%). Most patients (401; 77%) successfully completed cancer therapy. At the time of last data collection, the majority of patients were alive (430, 83%). Cardiac-related mortality was observed in 16%. Conclusions: The close collaboration between cardiology and oncology teams and timely cardiac monitoring was the key to the majority of patients to completing their prescribed cancer therapy.info:eu-repo/semantics/publishedVersio

    Absence of the caspases 1/11 modulates liver global lipid profile and gut microbiota in high-fat-diet-induced obese mice

    Get PDF
    Obesity is a chronic disease with rising worldwide prevalence and largely associated with several other comorbidities, such as cancer, non-alcoholic fatty liver disease (NAFLD), and metabolic syndrome. Hepatic steatosis, a hallmark of NAFLD, is strongly correlated with obesity and has been correlated with changes in the gut microbiota, which can promote its development through the production of short-chain fatty acids (SCFAs) that regulate insulin resistance, bile acid, choline metabolism, and inflammation. Recent studies have suggested a controversial role for the inflammasome/caspase-1 in the development of obesity and non-alcoholic steatohepatitis (NASH). Here, we evaluated the role of inflammasome NLRP3 and caspases 1/11 in the establishment of obesity and hepatic steatosis in diet-induced obese mice, correlating them with the global lipid profile of the liver and gut microbiota diversity. After feeding wild-type, caspases 1/11, and NLRP3 knockout mice with a standard fat diet (SFD) or a high-fat diet (HFD), we found that the caspases 1/11 knockout mice, but not NLRP3 knockout mice, were more susceptible to HFD-induced obesity, and developed enhanced hepatic steatosis even under SFD conditions. Lipidomics analysis of the liver, assessed by MALDI-MS analysis, revealed that the HFD triggered a significant change in global lipid profile in the liver of WT mice compared to those fed an SFD, and this profile was modified by the lack of caspases 1/11 and NLRP3. The absence of caspases 1/11 was also correlated with an increased presence of triacylglycerol in the liver. Gut microbial diversity analysis, using 16S rRNA gene sequencing, showed that there was also an increase of Proteobacteria and a higher Firmicutes/Bacteroidetes ratio in the gut of caspases 1/11 knockout mice fed an HFD. Overall, mice without caspases 1/11 harbored gut bacterial phyla involved with weight gain, obesity, and hepatic steatosis. Taken together, our data suggest an important role for caspases 1/11 in the lipid composition of the liver and in the modulation of the gut microbial community composition. Our results further suggest that HFD-induced obesity and the absence of caspases 1/11 may regulate both lipid metabolism and gut microbial diversity, and therefore may be associated with NAFLD and obesity10CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP312359/2016-02016/22577-6This research was funded by Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq -#312359/2016-0). CM was funded by the Canada Research Chair Program, the Canadian Foundation for Innovation, McGill University, and the Canadian Institutes for Health Research (PJT-149098). ME was funded by the São Paulo Research Foundation (FAPESP) (2016/22577-6)
    corecore