Ler Peter Pan hoje

Síntese dos temas constantes na obra Peter Pan. Literatura Infantil e Imaginário, publicada com a chancela do Centro de Investigação em Estudos da Criança da Universidade do Minho.Esta publicação teve o apoio financeiro da FCT (Fundação para a Ciência e a Tecnologia - Lisboa - Portugal) e do programa de financiamento POCH (Programa Operacional Capital Humano): financiamento comparticipado pelo Fundo Social Europeu e por fundos nacionais do MEC (Ministério da Educação e da Ciência - Lisboa - Portugal) (2015-2016).info:eu-repo/semantics/publishedVersio

Currículo y aseguramiento de la calidad en la educación superior

174 p. Recurso ElectrónicoEl presente libro titulado Currículo y aseguramiento de la calidad en la educación superior, es el resultado del Proyecto de Investigación denominado: El currículo en las políticas de aseguramiento de la calidad de la educación superior en América Latina. Estudio de caso: Colombia, Chile. Costa Rica y México, de la Línea de Investigación en Currículo y Universidad del Grupo de Investi gación en Currículo, Universidad y Sociedad de la Universidad del Tolima.Los capítulos están confi gurados a través de la metodología de análisis de contenido complementado con la emergencia y construcción conceptual basada en la teoría fundamentada, así como con el apoyo de investigaciones realizadas por el propio grupo de investigación además de los desarrollos académicos de diversos autores tanto nacionales como internacionales especialmente en el ámbito latinoamericano

Caracterización de las infecciones de transmisión sexual, su tratamiento farmacológico y la recurrencia en una población colombiana

Introduction: Sexually transmitted infections are a public health problem worldwide. Their inadequate antimicrobial management has been associated with a higher risk of recurrence.Objective: To characterize the main sexually transmitted infections, the adherence to clinical practice guidelines, and the factors associated with recurrence in Colombia.Materials and methods: We conducted an observational study to identify the main sexually transmitted infections, the sociodemographic variables, and the pharmacological management in a patient cohort from a population database of 6.5 million people affiliated with the Colombian health system. We made a multivariate analysis to identify the variables associated with recurrence.Results: We detected 3,158 patients with a mean age of 41.8 ± 14.5 years, of whom 63.1% were men. We found 4.030 episodes of sexually transmitted infections, predominantly urethral syndrome (27.5%). Only 13.6% of patients with urethral syndrome, ulcerative syndrome, or genital warts were managed in compliance with clinical practice guidelines and 20.6% were dispensed condoms; 16.7% of patients had recurrences and being male (OR=1.32; 95%CI 1.08-1.63), <30 years old (OR=1.72; 95%CI 1.40-2.13), being treated in municipalities other than capital cities (OR=1.43; 95%CI 1.06-1.94), and having received inadequate treatment for the first episode (OR=1.93; 95%CI 1.52-2.39) were associated with recurrence.Conclusions: The majority of patients with sexually transmitted infections were not treated in compliance with clinical practice guidelines and those who did not have adequate management had a higher risk of recurrence.Introducción. Las infecciones de transmisión sexual constituyen actualmente un problema de salud pública en el mundo. Su inadecuado tratamiento antimicrobiano se ha relacionado con un mayor riesgo de recurrencias.Objetivo. Caracterizar las principales infecciones de transmisión sexual, el cumplimiento de las guías de práctica clínica de Colombia y los factores asociados con las recurrencias.Materiales y métodos. Se hizo un estudio observacional para determinar las principales infecciones de transmisión sexual, las variables sociodemográficas y el tratamiento farmacológico en una cohorte de pacientes registrados en una base de datos poblacional de 6,5 millones de personas afiliadas al Sistema de Salud de Colombia. Se hizo un análisis multivariado para establecer las variables asociadas con las recurrencias.Resultados. Se detectaron 3.158 pacientes; su edad media era de 41,8 ±14,5 años y 63,1 % de ellos correspondía a hombres; se encontraron 4.030 episodios de infecciones de transmisión sexual con predominio del síndrome uretral (27,5 %). El 13,6 % de los pacientes con síndrome uretral, ulceroso o con verrugas genitales se manejó según las guías de práctica clínica. El 20,6 % tenía acceso a condones y el 16,7 % presentó recurrencias. Ser hombre (OR=1,32; IC95% 1,08-1,63), tener <30 años (OR=1,72; IC95% 1,40-2,13), ser tratado en municipios distintos a ciudades capitales (OR=1,43; IC95% 1,06-1,94) y haber recibido un tratamiento inadecuado en el primer episodio (OR=1,93; IC95% 1,52-2,39) fueron factores asociados con las recurrencias.Conclusiones. La mayoría de los pacientes con infecciones de transmisión sexual no fueron tratados según las guías de práctica clínica y quienes no tuvieron un manejo adecuado presentaban mayor riesgo de recurrencias

Tamanho de amostra para estimação da média e do coeficiente de variação em milho

The objective of this work was to determine the necessary sample size to estimate the mean and the coefficient of variation in traits of single, three‑way, and double maize crosses, in different harvests and precision levels, by resampling with replacement. Twelve characters were measured in 361, 373, and 416 plants, respectively, of the single, three‑way, and double‑cross hybrids of the 2008/2009 crop season, and in 1,777, 1,693, and 1,720 plants, respectively, of the single, three‑way, and double‑cross hybrids of the 2009/2010 crop season. Then, descriptive statistics were calculated and the sample size necessary to estimate the mean and coefficient of variation in precision levels – amplitudes of the confidence interval of 95% (AIC95%) of 5, 10, …, 35% of the mean and coefficient of variation – were determined by resampling with replacement. The sample size varied among hybrids, crop seasons, and traits. A larger sample size is necessary to estimate the mean and the coefficient of variation for the double-cross hybrid evaluated in the 2009/2010 crop season. For the same hybrid, crop, trait, and precision level, a larger sample size is necessary to estimate the mean compared to the sample size necessary to estimate the coefficient of variation. The measurement of 325, 150, 80, 60, 35, and 30 plants, respectively, is enough for the estimation of the mean and the coefficient of variation with AIC95% maximum of 10, 15, 20, 25, 30, and 35%, in all hybrids, crops and traits.O objetivo deste trabalho foi determinar o tamanho de amostra necessário para a estimação da média e do coeficiente de variação em caracteres de híbridos simples, triplo e duplo de milho, em diferentes safras e níveis de precisão, por reamostragem com reposição. Doze caracteres foram mensurados em 361, 373 e 416 plantas, respectivamente, de híbridos simples, triplo e duplo, na safra 2008/2009, e em 1.777, 1.693 e 1.720 plantas, respectivamente, de híbridos simples, triplo e duplo na safra 2009/2010. Calcularam-se as estatísticas descritivas e determinou-se o tamanho de amostra necessário para a estimação da média e do coeficiente de variação, em diferentes níveis de precisão – amplitudes do intervalo de confiança de 95% (AIC95%) de 5, 10, ..., 35% da média e do coeficiente de variação –, por reamostragem com reposição. O tamanho de amostra variou entre híbridos, safras e caracteres. É necessário maior tamanho de amostra para a estimação da média e do coeficiente de variação no híbrido duplo, avaliado na safra 2009/2010. Para um mesmo híbrido, safra, caractere e nível de precisão, é necessário maior tamanho de amostra para a estimação da média, em relação ao necessário para estimação do coeficiente de variação. A mensuração de 325, 150, 80, 60, 35 e 30 plantas, respectivamente, é suficiente para a estimação da média e do coeficiente de variação com AIC95% máximas de 10, 15, 20, 25, 30 e 35%, em todos os híbridos, safras e caracteres

Tromboprofilaxis en pacientes hospitalizados, ¿estamos haciendo lo correcto?

El tromboembolismo venoso conlleva una alta morbimortalidad en pacientes hospitalizados. Existe contundente evidencia sobre la costo-efectividad de la tromboprofilaxis, y no realizarla, se considera una práctica médica insegura. Materiales y métodos: Este estudio trasversal se realizó para evaluar la presencia de factores de riesgo y la realización de profilaxis para trombosis venosa profunda y embolismo pulmonar en pacientes hospitalizados en los servicios de medicina interna, gineco-obstetricia y quirúrgicas del Hospital Universitario San Jorge, en Pereira, Colombia, entre agosto de 2009 y marzo de 2010. Resultados: De 210 pacientes sólo el 29,5 % recibió profilaxis farmacológica pese a que hasta un 57,6% presentaron tres o más factores de riesgo para tromboembolismo venoso. Prácticamente la mitad de los pacientes de los servicios de medicina interna (47%) y de cirugía (56,3%) fueron clasificados como “alto o muy alto riesgo”. El servicio de cirugía fue el que más pacientes de muy alto riesgo albergó (81,8%); sin embargo, no recibieron tromboprofilaxis un 86% de estos pacientes. En contraste, el servicio de Medicina Interna fue el que realizó tromboprofilaxis de tipo farmacológico con más frecuencia (75,8% de los pacientes en este servicio la recibieron), mientras que en el servicio de gineco-Obstetricia solo un 2,7% de las pacientes la recibieron. Del total de pacientes que recibieron profilaxis farmacológica, un 4,3% no tenía indicación. Discusión: El análisis mostró que ser hospitalizado en el servicio de quirúrgica o de gineco-obstetricia de este institución se convierte en un factor de riesgo para no recibir tromboprofilaxis (p<0,001). Este estudio demuestra la necesidad de aplicar estrategias para que los médicos comprendan la importancia de la tromboprofilaxis y la apliquen de acuerdo con las guías mundialmente aceptadas.Deep vein thrombosis and pulmonary thromboembolism are important causes of morbidity and mortality in medically ill and surgical patients. There is a large body of evidence about the benefit of thromboprophylaxis and its cost-effectiveness, no performing prophylaxis is considered an unsafe medical care. Methods: This cross-sectional study was done to assess risk factors and prophylaxis given for deep venous thrombosis and pulmonary embolism in newly admitted medically ill and surgical patients during august 2009 to March 2010, in a tertiary teaching care center hospital in colombia (Hospital Universitario san Jorge). results: Only 29.5 percent out of 210 patients were given pharmacological prophylaxis, despite more than a half patients (57.6%) had three or more venous thromboembolism risk factors. Most of very high risk patients (81.8%) were at the surgical ward. The 47% and the 56,3 were classified as having high or very high risk in the internal medicine and surgical ward respectively. However, 86% of patients at surgical ward, and 97.3% at gynecology and obstetrics ward, did not receive prophylaxis, as long as, at internal medicine ward, more than a half patients did receive it (75.8%). Only 4.3% of patients were given prophylaxis without indication. discussion: Most of patients who did not receive pharmacological prophylaxis were at surgical ward (41.2%) and gynecology and obstetrics ward (48%) and being admitted in these becomes a risk factor for not receiving thromboprophylaxis (p<0.001). This study underlines the need to aggressively implement venous thromboembolism risk stratification strategy in medical and surgical patients and provide prophylaxis according to the published guidelines.http://revistas.utp.edu.co/index.php/revistamedic

Safety, Effectiveness, and Hemodynamic Performance of the Bovine Pericardium Organic Valvular Bioprosthesis

ABSTRACT Objective: To assess actual data on the safety, effectiveness, and hemodynamic performance of Bovine Pericardium Organic Valvular Bioprosthesis (BVP). Methods: The BIOPRO Trial is an observational, retrospective, non-comparative, non-randomized, and multicenter study. We collected data from 903 patients with symptomatic, moderate, or severe valve disease who underwent BVP implants in the timeframe from 2013 to 2020 at three Brazilian institutions. Death, valve-related adverse events (AEs), functional recovery, and hemodynamic performance were evaluated at the hospital, at discharge, and six months and one year later. Primary analysis compared late (> 30 days after implant) linearized rates of valve-related AEs, such as thromboembolism, valve thrombosis, major hemorrhage, major paravalvular leak, and endocarditis, following objective performance criteria (OPC). Analysis was performed to include at least 400 valve-years for each valve position (aortic and mitral) for complete comparisons to OPC. Kaplan-Meier survival and major adverse cardiovascular and cerebrovascular event analyses were also performed. Results: This retrospective study analyzed follow-up data collected from 903 patients (834.2 late patient-years) who have undergone surgery for 455 isolated aortic valve replacement (50.4%), 382 isolated mitral valve replacement (42.3%), and 66 combined valve replacement or other intervention (7.3%). The linearized rates of valve-related AEs were < 2 × OPC. One-year survival rates were 95.1% and 92.7% for aortic and mitral valve replacement, respectively. This study demonstrated an improvement in the New York Heart Association classification from baseline and hemodynamic performance within an expected range. Conclusion: According to this analysis, BVP meets world standards for safety and clinical efficacy

Decreased dentin tubules density and reduced thickness of peritubular dentin in hyperbilirubinemia-related green teeth

It is stated anecdotally that patients with liver diseases in childhood who develop green teeth have increased risk for rampant caries, which may be secondary to changes in dental structure. The aim of this study was to test the hypothesis that hyperbilirubinemia affects the dentin morphology of green teeth. Sixteen primary teeth were prepared and divided into two groups (green teeth, n = 8 and control, n = 8), which were transversely fractured across the cervical third of the dental crowns; dentin was prepared and sputter-coated with gold, and examined under a scanning electron microscope. The mean density and mean diameter of dentin tubules, as well as the thickness of peritubular dentin, were compared. Hyperbilirubinemia was associated with a decrease in the density of the dentin tubules (p< .01) and the thickness of peritubular dentin of green teeth (p< .01). There was a correlation between childhood hyperbilirubinemia and changes in the dentin morphology, including a decrease in the density of the dentin tubules and a reduction in the thickness of peritubular dentin in green teeth

Tamanho de amostra e relações lineares de caracteres morfológicos e produtivos de crambe

Os objetivos deste trabalho foram determinar o tamanho de amostra para a estimação da média de caracteres morfológicos e produtivos de crambe (Crambe abyssinica Hochst) e avaliar as relações entre esses caracteres. Foi conduzido um experimento a campo em Santa Maria, Estado do Rio Grande do Sul (latitude 29&deg;42'S, longitude 53&deg;49'W e 95m de altitude), no ano de 2008. Na colheita, foram selecionadas, aleatoriamente, 75 plantas e foram mensurados os caracteres morfológicos (altura de planta, número de rácemos por planta e comprimento médio dos rácemos por planta) e os produtivos (número de frutos por planta, número de frutos por rácemo e produtividade de grãos). Foi calculado o tamanho de amostra de cada caráter e investigada a relação entre os caracteres por meio de diagramas de dispersão, análises de correlação, de trilha e regressão. Na cultura de crambe, para estimar a média com uma mesma precisão, o tamanho de amostra (número de plantas) dos caracteres produtivos é maior que o dos morfológicos. O número de frutos por planta tem relação linear positiva com a produtividade de grãos e pode ser utilizado para seleção indireta

Tromboprofilaxis en pacientes hospitalizados, ¿estamos haciendo lo correcto?

Introducción: El tromboembolismo venoso conlleva una alta morbimortalidad en pacientes hospitalizados. Existe contundente evidencia sobre la costo-efectividad de la tromboprofilaxis, y no realizarla, se considera una práctica médica insegura. Materiales y métodos: Este estudio trasversal se realizó para evaluar la presencia de factores de riesgo y la realización de profilaxis para trombosis venosa profunda y embolismo pulmonar en pacientes hospitalizados en los servicios de medicina interna, gineco-obstetricia y quirúrgicas del Hospital Universitario San Jorge, en Pereira, Colombia, entre agosto de 2009 y marzo de 2010. Resultados: De 210 pacientes sólo el 29,5 % recibió profilaxis farmacológica pese a que hasta un 57,6% presentaron tres o más factores de riesgo para tromboembolismo venoso. Prácticamente la mitad de los pacientes de los servicios de medicina interna (47%) y de cirugía (56,3%) fueron clasificados como “alto o muy alto riesgo”. El servicio de cirugía fue el que más pacientes de muy alto riesgo albergó (81,8%); sin embargo, no recibieron tromboprofilaxis un 86% de estos pacientes. En contraste, el servicio de Medicina Interna fue el que realizó tromboprofilaxis de tipo farmacológico con más frecuencia (75,8% de los pacientes en este servicio la recibieron), mientras que en el servicio de gineco-Obstetricia solo un 2,7% de las pacientes la recibieron. Del total de pacientes que recibieron profilaxis farmacológica, un 4,3% no tenía indicación. Discusión: El análisis mostró que ser hospitalizado en el servicio de quirúrgica o de gineco-obstetricia de este institución se convierte en un factor de riesgo para no recibir tromboprofilaxis (p&lt;0,001). Este estudio demuestra la necesidad de aplicar estrategias para que los médicos comprendan la importancia de la tromboprofilaxis y la apliquen de acuerdo con las guías mundialmente aceptadas