Synthesis, physicochemical and photophysical characterization of 4-(1-Pyrenyl)-Butyl-α-d-mannopyranoside

Indexación: Web of Science; Scopus; Scielo.Glycolipids are biomolecules composed of a lipid chain (lipophilic) and a monosaccharide or oligosaccharide as hydrophilic group. Their chemical structure and biological role make them undoubtedly good candidates for a large and continuously growing number of biotechnological applications. Mannose is a carbohydrate present on membrane glycolipids of a wide number of pathogenic microorganisms (bacteria, fungi, protozoa, and viruses) and specifically recognized by several lectins. We synthesized a mannose derivative linked through a short methylene chain to a pyrene moiety which behaves as a surfactant, able to aggregate, and retains the photophysical properties of pyrene: showing comparable absorption and emission spectra, having lower fluorescence quantum yield and the ability to form excimer, and finally the ability to produce O-2((1)Delta(g)) with high quantum yields. Thus, this novel molecule would open future applications for detection (fluorescence) or inactivation (singlet oxygen) of bacterial pathogens, viruses, tumor cells, or particular cells.http://ref.scielo.org/pcn4d

Identification and quantification of drivers of forest degradation in tropical dry forests: a case study in Western Mexico

The intensity of forest degradation is linked to landowners' decisions on management of their shifting cultivation systems. Understanding the processes involved in this land use type is therefore essential for the design of sustainable forest management practices. However, knowledge of the processes and patterns of forest transition that result from this practice is extremely limited. In this study, we used spatially-explicit binary logistic regression to study the proximate factors that relate to forest degradation by combining biophysical and socio-economic variables. Our study region is within the Ayuquila Basin, in Western Mexico, a typical fragmented tropical dry forest landscape dominated by shifting cultivation. Through a survey and semi-structured interviews with community leaders, we obtained data on the forest resources and on the uses that people make of them. Detailed forest cover maps for 2004 and 2010 were produced from high-resolution SPOT 5 data, and ancillary geographical data were used to extract spatial variables. The degree of social marginalization of each community and the ratio of forest area to population size were the main factors positively correlated with the probability of the occurrence of forest degradation. Livestock management and use of fence posts by the communities were also positively associated with forest degradation. Among biophysical factors, forest degradation is more likely to occur in flatter areas. We conclude that local drivers of forest degradation include both socioeconomic and physical variables and that both of these factors need to be addressed at the landscape level while developing measures for activities related to REDD+. (C) 2015 Elsevier Ltd. All rights reserved

Genome-wide gene expression changes of Pseudomonas veronii 1YdBTEX2 during bioaugmentation in polluted soils.

Bioaugmentation aims to use the capacities of specific bacterial strains inoculated into sites to enhance pollutant biodegradation. Bioaugmentation results have been mixed, which has been attributed to poor inoculant growth and survival in the field, and, consequently, moderate catalytic performance. However, our understanding of biodegradation activity mostly comes from experiments conducted under laboratory conditions, and the processes occurring during adaptation and invasion of inoculants into complex environmental microbiomes remain poorly known. The main aim of this work was thus to study the specific and different cellular reactions of an inoculant for bioaugmentation during adaptation, growth and survival in natural clean and contaminated non-sterile soils, in order to better understand factors limiting bioaugmentation. As inoculant we focused on the monoaromatic compound-degrading bacterium Pseudomonas veronii 1YdBTEX2. The strain proliferated in all but one soil types in presence and in absence of exogenously added toluene. RNAseq and differential genome-wide gene expression analysis illustrated both a range of common soil responses such as increased nutrient scavenging and recycling, expression of defense mechanisms, as well as environment-specific reactions, notably osmoprotection and metal homeostasis. The core metabolism of P. veronii remained remarkably constant during exponential growth irrespective of the environment, with slight changes in cofactor regeneration pathways, possibly needed for balancing defense reactions. P. veronii displayed a versatile global program, enabling it to adapt to a variety of soil environments in the presence and even in absence of its target pollutant toluene. Our results thus challenge the widely perceived dogma of poor survival and growth of exogenous inoculants in complex microbial ecosystems such as soil and provide a further basis to developing successful bioaugmentation strategies

Oligodendroglioma anaplásico en el nervio óptico de un perro

Los gliomas son tumores no neuronales del tejido nervioso. En el Sistema Nervioso Central (SNC) dependiendo de su origen se clasifican en astrocitomas, oligodendrogliomas, tumores mixtos (oligoastrocitomas), ependimomas y papilomas de plexos coroideos. La retina y el nervio óptico pertenecen al SNC. Aunque las neoplasias primarias de la retina y el nervio óptico son bastante infrecuentes, son los meningiomas los tumores primarios más comunes siendo los gliomas más raros

Numerical study of efficiencies for box type solar cooker with internal reflectors

En este trabajo se muestran los resultados del estudio de las eficiencias termodinámicas de 1.a y 2.a ley aplicadas a 4 arreglos diferentes de estufas solares de tipo caja con reflectores internos. La estufa solar tiene 2 vidrios en su cubierta para disminuir la pérdida de calor por radiación y convección, y crear así el efecto invernadero. El interior de la estufa tiene espejos colocados a diferentes ángulos para dirigir la radiación solar hacia un recipiente con agua que se encuentra también dentro de la estufa. Los resultados obtenidos están basados en las temperaturas de calentamiento del agua, las cuales fueron obtenidas por medio de una simulación numérica que permite comparar los 4 arreglos de estufas solares bajo condiciones idénticas. El tratamiento de los resultados revela que la cantidad de energía que impacta en las estufas solares no es aprovechada de manera adecuada para los fines de calentamiento de agua. La mayor parte de la energía aprovechable se almacena en los vidrios de la tapa, lo que evidencia la necesidad de trabajar en el desarrollo de mejores materiales para mejorar tal situación.In this work, results of efficiencies for first and second law of thermodynamics applied to four box-type solar cookers with internal reflectors are shown. The solar cooker has two glasses on its cover to diminish the losses of heat for radiation and convection, besides creating the effect hothouse inside the cooker. The interior of the cooker has flat mirrors placed at different angles to reflect the solar radiation toward a recipient with water inside the cooker. The obtained results are based on heating water temperatures which were obtained by means of numeric simulation, allowing comparison under identical conditions of four solar cookers. The treatment of the results revealed that the quantity of energy that impacts on the solar cookers is not used in right way for the heating water ends. Most of the profitable energy is stored in the glasses of the cover, what evidences the necessity to work in the development of better materials to diminish such situation.Peer Reviewe

Counting matrices over finite fields with support on skew Young diagrams and complements of Rothe diagrams

We consider the problem of finding the number of matrices over a finite field with a certain rank and with support that avoids a subset of the entries. These matrices are a q-analogue of permutations with restricted positions (i.e., rook placements). For general sets of entries these numbers of matrices are not polynomials in q (Stembridge 98); however, when the set of entries is a Young diagram, the numbers, up to a power of q-1, are polynomials with nonnegative coefficients (Haglund 98). In this paper, we give a number of conditions under which these numbers are polynomials in q, or even polynomials with nonnegative integer coefficients. We extend Haglund's result to complements of skew Young diagrams, and we apply this result to the case when the set of entries is the Rothe diagram of a permutation. In particular, we give a necessary and sufficient condition on the permutation for its Rothe diagram to be the complement of a skew Young diagram up to rearrangement of rows and columns. We end by giving conjectures connecting invertible matrices whose support avoids a Rothe diagram and Poincar\'e polynomials of the strong Bruhat order.Comment: 24 pages, 9 figures, 1 tabl

Matone's Relation in the Presence of Gravitational Couplings

The prepotential in N=2 SUSY Yang-Mills theories enjoys remarkable properties. One of the most interesting is its relation to the coordinate on the quantum moduli space $u=$ that results into recursion equations for the coefficients of the prepotential due to instantons. In this work we show, with an explicit multi-instanton computation, that this relation holds true at arbitrary winding numbers. Even more interestingly we show that its validity extends to the case in which gravitational corrections are taken into account if the correlators are suitably modified. These results apply also to the cases in which matter in the fundamental and in the adjoint is included. We also check that the expressions we find satisfy the chiral ring relations for the gauge case and compute the first gravitational correction.Comment: 21 page

Neutrinos in Non-linear Structure Formation - a Simple SPH Approach

We present a novel method for implementing massive neutrinos in N-body simulations. Instead of sampling the neutrino velocity distribution by individual point particles we take neutrino free-streaming into account by treating it as an effective redshift dependent sound speed in a perfect isothermal fluid, and assume a relation between the sound speed and velocity dispersion of the neutrinos. Although the method fails to accurately model the true neutrino power spectrum, it is able to calculate the total matter power spectrum to the same accuracy as more complex hybrid neutrino methods, except on very small scales. We also present an easy way to update the publicly available Gadget-2 version with this neutrino approximation.Comment: 13 pages, 7 figure