797 research outputs found

    Coherent and semiclassical states in magnetic field in the presence of the Aharonov-Bohm solenoid

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    A new approach to constructing coherent states (CS) and semiclassical states (SS) in magnetic-solenoid field is proposed. The main idea is based on the fact that the AB solenoid breaks the translational symmetry in the xy-plane, this has a topological effect such that there appear two types of trajectories which embrace and do not embrace the solenoid. Due to this fact, one has to construct two different kinds of CS/SS, which correspond to such trajectories in the semiclassical limit. Following this idea, we construct CS in two steps, first the instantaneous CS (ICS) and the time dependent CS/SS as an evolution of the ICS. The construction is realized for nonrelativistic and relativistic spinning particles both in (2+1)- and (3+1)- dimensions and gives a non-trivial example of SS/CS for systems with a nonquadratic Hamiltonian. It is stressed that CS depending on their parameters (quantum numbers) describe both pure quantum and semiclassical states. An analysis is represented that classifies parameters of the CS in such respect. Such a classification is used for the semiclassical decompositions of various physical quantities.Comment: 35 pages, 2 figures. Some typos in (77), (101), and (135) corrected with respect to the published version. Results unchange

    Dummy Cb sebagai Alat Simulator Kubikel untuk Pemeliharaan Preventif dan Korektif Guna Mengurangi Frekuensi Padam Penyulang 20 Kv (Aplikasi pada Sistem Scada 20 Kv Pt.pln (Persero) Apd Jateng & DIY)

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    Meira Dwi Primanto, Priyo Sasmoko, in paper dummy CB as cubicle simulator for preventive and corrective maintenance to reduce off frequency 20 KV feeders (20 KV scada system at APD Central Java and Yogyakarta) explain that in 2013, the APD PT.PLN Central Java and Yogyakarta are conducting integration to SCADA at 20 KV feeders in distribution substation. For the next stage has been installed SCADA maintenance should be done periodically. Maintenance can be planned or due to interference with the SCADA system. Maintenance is usually done by the team must perform SCADA Distribution feeder outages and transfer of the load. In the installation of equipment, SCADA team should get a working permit to shut down the feeder, and to transfer the load to another feeder, so that the work has to get permission. SCADA systems are already installed requires maintenance to keep the system reliability. When maintenance SCADA, feeders should be extinguished, whereas for medium voltage customers such as factories, hospitals, and airports should always be channeled electrical energy. Feeder outages and load Delegation KWH lost causes. To the authors attempt to provide solutions that can overcome the missing KWH with a tool innovations made. The author makes a tool such as a dummy circuit breaker simulator 20 KV cubicles. This tool serves Especially when employees perform maintenance or investigation SCADA Disorders, which aims for 20 KV feeders should not be extinguished when performing preventive and corrective maintenance. So the number of frequency of feeder outages can be reduced

    Alkylation-induced colon tumorigenesis in mice deficient in the Mgmt and Msh6 proteins

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    O[superscript 6]-methylguanine DNA methyltransferase (MGMT) suppresses mutations and cell death that result from alkylation damage. MGMT expression is lost by epigenetic silencing in a variety of human cancers including nearly half of sporadic colorectal cancers, suggesting that this loss maybe causal. Using mice with a targeted disruption of the Mgmt gene, we tested whether Mgmt protects against azoxymethane (AOM)-induced colonic aberrant crypt foci (ACF), against AOM and dextran sulfate sodium (DSS)-induced colorectal adenomas and against spontaneous intestinal adenomas in Apc[superscript Min] mice. We also examined the genetic interaction of the Mgmt null gene with a DNA mismatch repair null gene, namely Msh6. Both Mgmt and Msh6 independently suppress AOM-induced ACF, and combination of the two mutant alleles had a multiplicative effect. This synergism can be explained entirely by the suppression of alkylation-induced apoptosis when Msh6 is absent. In addition, following AOM+DSS treatment Mgmt protected against adenoma formation to the same degree as it protected against AOM-induced ACF formation. Finally, Mgmt deficiency did not affect spontaneous intestinal adenoma development in Apc[superscript Min/+] mice, suggesting that Mgmt suppresses intestinal cancer associated with exogenous alkylating agents, and that endogenous alkylation does not contribute to the rapid tumor development seen in Apc[superscript Min/+] mice.National Institutes of Health (U.S.) (grant ES02109)National Institutes of Health (U.S.) (grant CA75576)American Cancer Society (Research Professor

    Nonparametric estimation of conditional transition probabilities in a non-Markov illness-death model

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    One important goal in multi-state modeling is the estimation of transition probabilities. In longitudinal medical studies these quantities are particularly of interest since they allow for long-term predictions of the process. In recent years signi ficant contributions have been made regarding this topic. However, most of the approaches assume independent censoring and do not account for the influence of covariates. The goal of the paper is to introduce feasible estimation methods for the transition probabilities in an illness-death model conditionally on current or past covariate measures. All approaches are evaluated through a simulation study, leading to a comparison of two di erent estimators. The proposed methods are illustrated using real a colon cancer data set.This research was nanced by FEDER Funds through Programa Operacional Factores de Competitividade COMPETE and by Portuguese Funds through FCT - Funda ção para a Cência e a Tecnologia, within Projects Est-C/MAT/UI0013/2011 and PTDC/MAT/104879/2008. We also acknowledge nancial support from the project Grants MTM2008-03129 and MTM2011-23204 (FEDER support included) of the Spanish Ministerio de Ciencia e Innovaci on and 10PXIB300068PR of the Xunta de Galicia. Partial support from a grant from the US National Security Agency (H98230-11-1-0168) is greatly appreciated

    Mining structural signatures in proteins using intrachain interactions.

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    In this work we use a data mining approach to analyze similarity of proteins and to extract conserved information on dissimilar sequences of proteins of the same family.X-meeting 2007

    Coherent states of non-relativistic electron in magnetic-solenoid field

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    We construct coherent states of a nonrelativistic electron in the magnetic-solenoid field, which is a superposition of the Aharonov-Bohm field and a collinear uniform magnetic field. In the problem under consideration there are two kind of coherent states, the first kind corresponds to classical trajectories which embrace the solenoid and the second one to trajectories which do not. Mean coordinates in the constructed coherent states are moving along classical trajectories, the coherent states maintain their form under the time evolution, and represent a complete set of functions, which can be useful in semi classical calculations. In the absence of the Aharonov-Bohm filed these states are reduced to the well-known in the case of uniform magnetic field Malkin-Man'ko coherent states.Comment: 11 pages, version accepted for publication in J. Phys. A, 3 figures adde

    Contribuição de sistema de gerenciamento de conteúdo Web para a gestão do conhecimento em redes de PD&I na Embrapa.

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    O Plano Diretor da Embrapa (V PDE, 2008) destaca a importância estratégica da formação de arranjos inter-institucionais, como as Redes de Pesquisa, Desenvolvimento & Inovação ? PD&I, tendo em vista que a geração de inovações envolve um processo interativo, embasado pelo estabelecimento de relacionamentos visando à produção e difusão de conhecimentos novos e economicamente úteis (LUNDVALL,1992). A fim de apoiar a gestão do conhecimento no âmbito de redes de PD&I, a Embrapa Informática Agropecuária iniciou em 2006 a utilização do sistema gestor de conteúdo Web Plone

    Transition to adult care of young people with congenital heart disease: Impact of a service on knowledge and self-care skills, and correlates of a successful transition

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    Aims Less than one-third of adolescents with congenital heart disease (CHD) successfully transition to adult care, missing out on education of their cardiac condition, and risking loss to follow-up. We assessed the efficacy of our transition clinic on patient education and empowerment and identified correlates of successful transition. Methods and results Overall, 592 patients were seen at least once in our transition service between 2015 and 2022 (age 15.2 ± 1.8 years, 47.5% female). Most adolescents (53%) had moderate CHD, followed by simple (27.9%) and severe (19.1%) CHD. Learning disability (LD) was present in 18.9% and physical disability (PD) in 4.7%. In patients without LD, knowledge of their cardiac condition improved significantly from the first to the second visit (naming their condition: from 20 to 52.3%, P 0.05). Treatment adherence and management involvement, self-reported anxiety, and dental care awareness did not change over time. Successful transition (attendance of ≥ 2 clinics) was achieved in 49.3%. Younger age at the first visit, simpler CHD, and absence of PD were associated with successful transition. Conclusion A transition service positively impacts on patient education and empowerment in most CHD adolescents transitioning to adult care. Strategies to promote a tailored support for patients with LD should be sought, and earlier engagement should be encouraged to minimize follow-up losses

    MOF-mediated synthesis of supported Fe-doped Pd nanoparticles under mild conditions for magnetically recoverable catalysis

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    Metal-organic framework (MOF)-driven synthesis is considered as a promising alternative for the development of new catalytic materials with well-designed active sites. This synthetic approach is used here to gradually transform a new bimetallic MOF, with Pd and Fe as the metal components, by the in situ generation of aniline under mild conditions. This methodology results in a compositionally homogeneous nanocomposite formed by Fe-doped Pd nanoparticles that, in turn, are supported on iron oxide-doped carbon. The nanocomposite has been fully characterized by several techniques such as IR and Raman spectroscopy, TEM, XPS, and XAS. The performance of this nanocomposite as an heterogeneous catalyst for hydrogenation of nitroarenes and nitrobenzene coupling with benzaldehyde has been evaluated, proving it to be an efficient and reusable catalyst

    Low-temperature hydroformylation of ethylene by phosphorous stabilized Rh sites in a one-pot synthesized Rh-(O)-P-MFI zeolite

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    Zeolites containing Rh single sites stabilized by phosphorous were prepared through a one-pot synthesis method and are shown to have superior activity and selectivity for ethylene hydroformylation at low temperature (50 °C). Catalytic activity is ascribed to confined Rh2O3 clusters in the zeolite which evolve under reaction conditions into single Rh3+ sites. These Rh3+ sites are effectively stabilized in a Rh-(O)-P structure by using tetraethylphosphonium hydroxide as a template, which generates in situ phosphate species after H2 activation. In contrast to Rh2O3, confined Rh0 clusters appear less active in propanal production and ultimately transform into Rh(I)(CO)2 under similar reaction conditions. As a result, we show that it is possible to reduce the temperature of ethylene hydroformylation with a solid catalyst down to 50 °C, with good activity and high selectivity, by controlling the electronic and morphological properties of Rh species and the reaction conditions.13 página
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