On the electroweak phase transition in the Minimal Supersymmetric Standard Model

We study the finite-temperature effective potential of the Minimal Supersymmetric Standard Model, in the limit of only one light Higgs boson. Because of the large top Yukawa coupling, there can be significant differences with respect to the Standard Model case: for given values of the Higgs and top masses, little supersymmetry breaking in the stop sector can make the phase transition more strongly first-order. After including the full structure of the stop mass matrix, the most important experimental constraints and the leading plasma effects, we find that the present limits on Higgs and squark masses are still compatible with the scenario of electroweak baryogenesis, in a small region of parameter space corresponding to m_h \simlt 70 \gev and \msba \simlt 105 \gev.Comment: 10 A4 pages, 7 figures available upon request, CERN-TH.6833/93, IEM-FT-69/93 (one paragraph expanded for clarity

Expectations of rehabilitation following lower limb amputation: a qualitative study.

To explore the expectations of patients about to undergo prosthetic rehabilitation following a lower limb amputation

The Gauging of Five-dimensional, N=2 Maxwell-Einstein Supergravity Theories coupled to Tensor Multiplets

We study the general gaugings of N=2 Maxwell-Einstein supergravity theories (MESGT) in five dimensions, extending and generalizing previous work. The global symmetries of these theories are of the form SU(2)_R X G, where SU(2)_R is the R-symmetry group of the N=2 Poincare superalgebra and G is the group of isometries of the scalar manifold that extend to symmetries of the full action. We first gauge a subgroup K of G by turning some of the vector fields into gauge fields of K while dualizing the remaining vector fields into tensor fields transforming in a non-trivial representation of K. Surprisingly, we find that the presence of tensor fields transforming non-trivially under the Yang-Mills gauge group leads to the introduction of a potential which does not admit an AdS ground state. Next we give the simultaneous gauging of the U(1)_R subgroup of SU(2)_R and a subgroup K of G in the presence of K-charged tensor multiplets. The potential introduced by the simultaneous gauging is the sum of the potentials introduced by gauging K and U(1)_R separately. We present a list of possible gauge groups K and the corresponding representations of tensor fields. For the exceptional supergravity we find that one can gauge the SO^*(6) subgroup of the isometry group E_{6(-26)} of the scalar manifold if one dualizes 12 of the vector fields to tensor fields just as in the gauged N=8 supergravity.Comment: Latex file, 23 page

Vacuum Stability, Perturbativity, and Scalar Singlet Dark Matter

We analyze the one-loop vacuum stability and perturbativity bounds on a singlet extension of the Standard Model (SM) scalar sector containing a scalar dark matter candidate. We show that the presence of the singlet-doublet quartic interaction relaxes the vacuum stability lower bound on the SM Higgs mass as a function of the cutoff and lowers the corresponding upper bound based on perturbativity considerations. We also find that vacuum stability requirements may place a lower bound on the singlet dark matter mass for given singlet quartic self coupling, leading to restrictions on the parameter space consistent with the observed relic density. We argue that discovery of a light singlet scalar dark matter particle could provide indirect information on the singlet quartic self-coupling.Comment: 25 pages, 10 figures; v2 - fixed minor typos; v3 - added to text discussions of other references, changed coloring of figures for easier black and white viewin

Effects of ocean acidification on invertebrate settlement at volcanic CO<inf>2</inf> vents

We present the first study of the effects of ocean acidification on settlement of benthic invertebrates and microfauna. Artificial collectors were placed for 1 month along pH gradients at CO2 vents off Ischia (Tyrrhenian Sea, Italy). Seventy-nine taxa were identified from six main taxonomic groups (foraminiferans, nematodes, polychaetes, molluscs, crustaceans and chaetognaths). Calcareous foraminiferans, serpulid polychaetes, gastropods and bivalves showed highly significant reductions in recruitment to the collectors as pCO2 rose from normal (336-341 ppm, pH 8.09-8.15) to high levels (886-5,148 ppm) causing acidified conditions near the vents (pH 7.08-7.79). Only the syllid polychaete Syllis prolifera had higher abundances at the most acidified station, although a wide range of polychaetes and small crustaceans was able to settle and survive under these conditions. A few taxa (Amphiglena mediterranea, Leptochelia dubia, Caprella acanthifera) were particularly abundant at stations acidified by intermediate amounts of CO2 (pH 7. 41-7.99). These results show that increased levels of CO2 can profoundly affect the settlement of a wide range of benthic organisms. © 2010 Springer-Verlag

Time to go global: a consultation on global health competencies for postgraduate doctors

BACKGROUND: Globalisation is having profound impacts on health and healthcare. We solicited the views of a wide range of stakeholders in order to develop core global health competencies for postgraduate doctors. METHODS: Published literature and existing curricula informed writing of seven global health competencies for consultation. A modified policy Delphi involved an online survey and face-to-face and telephone interviews over three rounds. RESULTS: Over 250 stakeholders participated, including doctors, other health professionals, policymakers and members of the public from all continents of the world. Participants indicated that global health competence is essential for postgraduate doctors and other health professionals. Concerns were expressed about overburdening curricula and identifying what is 'essential' for whom. Conflicting perspectives emerged about the importance and relevance of different global health topics. Five core competencies were developed: (1) diversity, human rights and ethics; (2) environmental, social and economic determinants of health; (3) global epidemiology; (4) global health governance; and (5) health systems and health professionals. CONCLUSIONS: Global health can bring important perspectives to postgraduate curricula, enhancing the ability of doctors to provide quality care. These global health competencies require tailoring to meet different trainees' needs and facilitate their incorporation into curricula. Healthcare and global health are ever-changing; therefore, the competencies will need to be regularly reviewed and updated

Lepton flavour violation in the MSSM

We derive new constraints on the quantities delta_{XY}^{ij}, X,Y=L,R, which parametrise the flavour-off-diagonal terms of the charged slepton mass matrix in the MSSM. Considering mass and anomalous magnetic moment of the electron we obtain the bound |delta^{13}_{LL} delta^{13}_{RR}|<0.1 for tan beta=50, which involves the poorly constrained element delta^{13}_{RR}. We improve the predictions for the decays tau -> mu gamma, tau -> e gamma and mu -> e gamma by including two-loop corrections which are enhanced if tan beta is large. The finite renormalisation of the PMNS matrix from soft SUSY-breaking terms is derived and applied to the charged-Higgs-lepton vertex. We find that the experimental bound on BR(tau -> e gamma) severely limits the size of the MSSM loop correction to the PMNS element U_{e3}, which is important for the proper interpretation of a future U_{e3} measurement. Subsequently we confront our new values for delta^{ij}_{LL} with a GUT analysis. Further, we include the effects of dimension-5 Yukawa terms, which are needed to fix the Yukawa unification of the first two generations. If universal supersymmetry breaking occurs above the GUT scale, we find the flavour structure of the dimension-5 Yukawa couplings tightly constrained by mu -> e gamma.Comment: 37 pages, 15 figures; typo in Equation (35) and (49) correcte

Probing CPT in transitions with entangled neutral kaons

In this paper we present a novel CPT symmetry test in the neutral kaon system based, for the first time, on the direct comparison of the probabilities of a transition and its CPT reverse. The required interchange of in out states for a given process is obtained exploiting the Einstein-Podolsky-Rosen correlations of neutral kaon pairs produced at a phi-factory. The observable quantities have been constructed by selecting the two semileptonic decays for flavour tag, the pi and 3 pi(0) decays for CP tag and the time orderings of the decay pairs. The interpretation in terms of the standard Weisskopf-Wigner approach to this system, directly connects CPT violation in these observables to the violating R delta parameter in the mass matrix of K-0 (K) over bar (0), a genuine CPT violating effect independent of Delta Gamma and not requiring the decay as an essential ingredient. Possible spurious effects induced by CP violation in the decay and/or a violation of the Delta S = Delta Q rule have been shown to be well under control. The proposed test is thus fully robust, and might shed light on possible new CPT violating mechanisms, or further improve the precision of the present experimental limits. It could be implemented at the DA Phi NE facility in Frascati, where the KLOE-2 experiment might reach a statistical sensitivity of O (10(-3)) on the newly proposed observable quantities

Unified N=2 Maxwell-Einstein and Yang-Mills-Einstein Supergravity Theories in Four Dimensions

We study unified N=2 Maxwell-Einstein supergravity theories (MESGTs) and unified Yang-Mills Einstein supergravity theories (YMESGTs) in four dimensions. As their defining property, these theories admit the action of a global or local symmetry group that is (i) simple, and (ii) acts irreducibly on all the vector fields of the theory, including the ``graviphoton''. Restricting ourselves to the theories that originate from five dimensions via dimensional reduction, we find that the generic Jordan family of MESGTs with the scalar manifolds [SU(1,1)/U(1)] X [SO(2,n)/SO(2)X SO(n)] are all unified in four dimensions with the unifying global symmetry group SO(2,n). Of these theories only one can be gauged so as to obtain a unified YMESGT with the gauge group SO(2,1). Three of the four magical supergravity theories defined by simple Euclidean Jordan algebras of degree 3 are unified MESGTs in four dimensions. Two of these can furthermore be gauged so as to obtain 4D unified YMESGTs with gauge groups SO(3,2) and SO(6,2), respectively. The generic non-Jordan family and the theories whose scalar manifolds are homogeneous but not symmetric do not lead to unified MESGTs in four dimensions. The three infinite families of unified five-dimensional MESGTs defined by simple Lorentzian Jordan algebras, whose scalar manifolds are non-homogeneous, do not lead directly to unified MESGTs in four dimensions under dimensional reduction. However, since their manifolds are non-homogeneous we are not able to completely rule out the existence of symplectic sections in which these theories become unified in four dimensions.Comment: 47 pages; latex fil

A computational framework to emulate the human perspective in flow cytometric data analysis

Background: In recent years, intense research efforts have focused on developing methods for automated flow cytometric data analysis. However, while designing such applications, little or no attention has been paid to the human perspective that is absolutely central to the manual gating process of identifying and characterizing cell populations. In particular, the assumption of many common techniques that cell populations could be modeled reliably with pre-specified distributions may not hold true in real-life samples, which can have populations of arbitrary shapes and considerable inter-sample variation. &lt;p/&gt;Results: To address this, we developed a new framework flowScape for emulating certain key aspects of the human perspective in analyzing flow data, which we implemented in multiple steps. First, flowScape begins with creating a mathematically rigorous map of the high-dimensional flow data landscape based on dense and sparse regions defined by relative concentrations of events around modes. In the second step, these modal clusters are connected with a global hierarchical structure. This representation allows flowScape to perform ridgeline analysis for both traversing the landscape and isolating cell populations at different levels of resolution. Finally, we extended manual gating with a new capacity for constructing templates that can identify target populations in terms of their relative parameters, as opposed to the more commonly used absolute or physical parameters. This allows flowScape to apply such templates in batch mode for detecting the corresponding populations in a flexible, sample-specific manner. We also demonstrated different applications of our framework to flow data analysis and show its superiority over other analytical methods. &lt;p/&gt;Conclusions: The human perspective, built on top of intuition and experience, is a very important component of flow cytometric data analysis. By emulating some of its approaches and extending these with automation and rigor, flowScape provides a flexible and robust framework for computational cytomics