1,668 research outputs found

    Civil Conflict and Three Dimensions of Ethnic Inequality

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    Presentado como comunicación en el Department of Political Science, Columbia University in the City of New York, en noviembre de 2012 Presentado como comunicación en "Concentration on Conflict", Civil Conflict and Rationality. Barcelona GSE Summer Forum, celebrado del 10 al 12 de junio de 2013 en Barcelona (España)Most empirical studies on civil conflict are not able to find a significant relationship between interpersonal-measures of economic inequality and the likelihood of conflict. When individuals belong to groups, general inequality (measured by the Gini) can be decomposed into three components: between-group inequality (BGI), within-group inequality (WGI), and ‘Overlap’ (which is inversely related to the economic segregation of groups). This paper shows that is possible to establish a robust empirical relation between group-based measures of income differences and con- flict. Drawing on over 200 individual-level surveys from 89 countries, we create a new data set that allows us to measure these three components and to examine their empirical relationship with civil conflict. Consistent with Esteban and Ray’s (2011) argument about the need for labor and capital to fight civil wars, we find a strong, robust positive association between WGI and civil conflict. And consistent with the “contact hypothesis” in sociology, we find that the economic segregation of groups (as measured by a lower Overlap component) is often associated with more civil conflict. Since some components of inequality are associated with more civil conflict but others are associated with less, the analysis helps explain why it has been difficult to identify a relationship between general inequality and civil war. And the strong finding for WGI underscores the value of developing clear theories about how the internal characteristics of groups influence the incidence of civil conflictPeer Reviewe

    Microstructural modifications in tungsten induced by high flux plasma exposure : TEM examination

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    We have performed microstructural characterization using transmission electron microscopy (TEM) techniques to reveal nanometric features in the sub-surface region of tungsten samples exposed to high flux, low energy deuterium plasma. TEM examination revealed formation of a dense dislocation network and dislocation tangles, overall resulting in a strong increase in the dislocation density by at least one order of magnitude as compared to the initial one. Plasma-induced dislocation microstructure vanishes beyond a depth of about 10 mu m from the top of the exposed surface where the dislocation density and its morphology becomes comparable to the reference microstructure. Interstitial edge dislocation loops with Burgers vector a(0)/2 and a(0) were regularly observed within 6 mu m of the sub-surface region of the exposed samples, but absent in the reference material. The presence of these loops points to a co-existence of nanometric D bubbles, growing by loop punching mechanism, and sub-micron deuterium flakes, resulting in the formation of surface blisters, also observed here by scanning electron microscopy

    “Varopoulos paradigm”: Mackey property versus metrizability in topological groups.

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    The class of all locally quasi-convex (lqc) abelian groups contains all locally convex vector spaces (lcs) considered as topological groups. Therefore it is natural to extend classical properties of locally convex spaces to this larger class of abelian topological groups. In the present paper we consider the following well known property of lcs: “A metrizable locally convex space carries its Mackey topology ”. This claim cannot be extended to lqc-groups in the natural way, as we have recently proved with other coauthors (Außenhofer and de la Barrera Mayoral in J Pure Appl Algebra 216(6):1340–1347, 2012; Díaz Nieto and Martín Peinador in Descriptive Topology and Functional Analysis, Springer Proceedings in Mathematics and Statistics, Vol 80 doi:10.1007/978-3-319-05224-3_7, 2014; Dikranjan et al. in Forum Math 26:723–757, 2014). We say that an abelian group G satisfies the Varopoulos paradigm (VP) if any metrizable locally quasi-convex topology on G is the Mackey topology. In the present paper we prove that in any unbounded group there exists a lqc metrizable topology that is not Mackey. This statement (Theorem C) allows us to show that the class of groups satisfying VP coincides with the class of finite exponent groups. Thus, a property of topological nature characterizes an algebraic feature of abelian groups

    Impact of minority concentration on fundamental (H)D ICRF heating performance in JET-ILW

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    ITER will start its operation with non-activated hydrogen and helium plasmas at a reduced magnetic field of B-0 = 2.65 T. In hydrogen plasmas, the two ion cyclotron resonance frequency (ICRF) heating schemes available for central plasma heating (fundamental H majority and 2nd harmonic He-3 minority ICRF heating) are likely to suffer from relatively low RF wave absorption, as suggested by numerical modelling and confirmed by previous JET experiments conducted in conditions similar to those expected in ITER's initial phase. With He-4 plasmas, the commonly adopted fundamental H minority heating scheme will be used and its performance is expected to be much better. However, one important question that remains to be answered is whether increased levels of hydrogen (due to e. g. H pellet injection) jeopardize the high performance usually observed with this heating scheme, in particular in a full-metal environment. Recent JET experiments performed with the ITER-likewall shed some light onto this question and the main results concerning ICRF heating performance in L-mode discharges are summarized here

    Validity of the N\'{e}el-Arrhenius model for highly anisotropic Co_xFe_{3-x}O_4 nanoparticles

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    We report a systematic study on the structural and magnetic properties of Co_{x}Fe_{3-x}O_{4} magnetic nanoparticles with sizes between 55 to 2525 nm, prepared by thermal decomposition of Fe(acac)_{3} and Co(acac)_{2}. The large magneto-crystalline anisotropy of the synthesized particles resulted in high blocking temperatures (4242 K \leqq TBT_B 345\leqq 345 K for 55 \leqq d 13\leqq 13 nm ) and large coercive fields (HC1600H_C \approxeq 1600 kA/m for T=5T = 5 K). The smallest particles (=5=5 nm) revealed the existence of a magnetically hard, spin-disordered surface. The thermal dependence of static and dynamic magnetic properties of the whole series of samples could be explained within the N\'{e}el-Arrhenius relaxation framework without the need of ad-hoc corrections, by including the thermal dependence of the magnetocrystalline anisotropy constant K1(T)K_1(T) through the empirical Br\"{u}khatov-Kirensky relation. This approach provided K1(0)K_1(0) values very similar to the bulk material from either static or dynamic magnetic measurements, as well as realistic values for the response times (τ01010\tau_0 \simeq 10^{-10} s). Deviations from the bulk anisotropy values found for the smallest particles could be qualitatively explained based on Zener\'{}s relation between K1(T)K_1(T) and M(T)

    A primer-independent DNA polymerase-based method for competent whole-genome amplification of intermediate to high GC sequences

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    The dataset (raw sequencing data) that supports the findings of this study are archived in the Universidad Autónoma de Madrid data repository e‐cienciaDatos in DOI: 10.21950/HCNDGMultiple displacement amplification (MDA) has proven to be a useful technique for obtaining large amounts of DNA from tiny samples in genomics and metagenomics. However, MDA has limitations, such as amplification artifacts and biases that can interfere with subsequent quantitative analysis. To overcome these challenges, alternative methods and engineered DNA polymerase variants have been developed. Here, we present new MDA protocols based on the primer-independent DNA polymerase (piPolB), a replicative-like DNA polymerase endowed with DNA priming and proofreading capacities. These new methods were tested on a genomes mixture containing diverse sequences with high-GC content, followed by deep sequencing. Protocols relying on piPolB as a single enzyme cannot achieve competent amplification due to its limited processivity and the presence of ab initio DNA synthesis. However, an alternative method called piMDA, which combines piPolB with Φ29 DNA polymerase, allows proficient and faithful amplification of the genomes. In addition, the prior denaturation step commonly performed in MDA protocols is dispensable, resulting in a more straightforward protocol. In summary, piMDA outperforms commercial methods in the amplification of genomes and metagenomes containing high GC sequences and exhibits similar profiling, error rate and variant determination as the non-amplified samplesMCIN/AEI/10.13039/501100011033 and ERDF A way of making Europe [PGC2018-09723-A-I00 and PID2021-123403NB-I00 to M.R.R.]; C. Egas’ laboratory was funded by the European Union′s Horizon 2020 Research and Innovation Program [685474]; METAFLUIDICS project; C.D.O. and C.M.C. were holder of Fellowships from the Spanish Ministry of University [FPU16/02665] and Spanish Ministry of Science and Innovation [PRE2019-087304], respectivel

    The sequence selectivity of KSRP explains its flexibility in the recognition of the RNA targets

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    K-homology (KH) splicing regulator protein (KSRP) is a multi-domain RNA-binding protein that regulates different steps of mRNA metabolism, from mRNA splicing to mRNA decay, interacting with a broad range of RNA sequences. To understand how KSRP recognizes its different RNA targets it is necessary to define the general rules of KSRP–RNA interaction. We describe here a complete scaffold-independent analysis of the RNA-binding potential of the four KH domains of KSRP. The analysis shows that KH3 binds to the RNA with a significantly higher affinity than the other domains and recognizes specifically a G-rich target. It also demonstrates that the other KH domains of KSRP display different sequence preferences explaining the broad range of targets recognized by the protein. Further, KSRP shows a strong negative selectivity for sequences containing several adjacent Cytosines limiting the target choice of KSRP within single-stranded RNA regions. The in-depth analysis of the RNA-binding potential of the KH domains of KSRP provides us with an understanding of the role of low sequence specificity domains in RNA recognition by multi-domain RNA-binding proteins

    The Role of Peripheral Amide Groups as Hydrogen-Bonding Directors in the Tubular Self-Assembly of Dinucleobase Monomers

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    Nanotubes are a fascinating kind of self‐assembled structure which have a wide interest and potential in supramolecular chemistry. We demonstrated that nanotubes of defined dimensions can be produced from dinucleobase monomers through two decoupled hierarchical cooperative processes: cyclotetramerization and supramolecular polymerization. Here we analyze the role of peripheral amide groups, which can form an array of hydrogen bonds along the tube axis, on this self‐assembly process. A combination of (1)H NMR and CD spectroscopy techniques allowed us to analyze quantitatively the thermodynamics of each of these two processes separately. We found out that the presence of these amide directors is essential to guide the polymerization event and that their nature and number have a strong influence, not only on the stabilization of the stacks of macrocycles, but also on the supramolecular polymerization mechanism
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