494 research outputs found
Classical motion in force fields with short range correlations
We study the long time motion of fast particles moving through time-dependent
random force fields with correlations that decay rapidly in space, but not
necessarily in time. The time dependence of the averaged kinetic energy and
mean-squared displacement is shown to exhibit a large degree of universality;
it depends only on whether the force is, or is not, a gradient vector field.
When it is, p^{2}(t) ~ t^{2/5} independently of the details of the potential
and of the space dimension. Motion is then superballistic in one dimension,
with q^{2}(t) ~ t^{12/5}, and ballistic in higher dimensions, with q^{2}(t) ~
t^{2}. These predictions are supported by numerical results in one and two
dimensions. For force fields not obtained from a potential field, the power
laws are different: p^{2}(t) ~ t^{2/3} and q^{2}(t) ~ t^{8/3} in all dimensions
d\geq 1
Determination of the time-dependent reaction coefficient and the heat flux in a nonlinear inverse heat conduction problem
Diffusion processes with reaction generated by a nonlinear source are commonly encountered in practical applications related to ignition, pyrolysis and polymerization. In such processes, determining the intensity of reaction in time is of crucial importance for control and monitoring purposes. Therefore, this paper is devoted to such an identification problem of determining the time-dependent coefficient of a nonlinear heat source together with the unknown heat flux at an inaccessible boundary of a one-dimensional slab from temperature measurements at two sensor locations in the context of nonlinear transient heat conduction. Local existence and uniqueness results for the inverse coefficient problem are proved when the first three derivatives of the nonlinear source term are Lipschitz continuous functions. Furthermore, the conjugate gradient method (CGM) for separately reconstructing the reaction coefficient and the heat flux is developed. The ill-posedness is overcome by using the discrepancy principle to stop the iteration procedure of CGM when the input data is contaminated with noise. Numerical results show that the inverse solutions are accurate and stable
Tsallis non-extensive statistics, intermittent turbulence, SOC and chaos in the solar plasma. Part one: Sunspot dynamics
In this study, the nonlinear analysis of the sunspot index is embedded in the
non-extensive statistical theory of Tsallis. The triplet of Tsallis, as well as
the correlation dimension and the Lyapunov exponent spectrum were estimated for
the SVD components of the sunspot index timeseries. Also the multifractal
scaling exponent spectrum, the generalized Renyi dimension spectrum and the
spectrum of the structure function exponents were estimated experimentally and
theoretically by using the entropy principle included in Tsallis non extensive
statistical theory, following Arimitsu and Arimitsu. Our analysis showed
clearly the following: a) a phase transition process in the solar dynamics from
high dimensional non Gaussian SOC state to a low dimensional non Gaussian
chaotic state, b) strong intermittent solar turbulence and anomalous
(multifractal) diffusion solar process, which is strengthened as the solar
dynamics makes phase transition to low dimensional chaos in accordance to
Ruzmaikin, Zeleny and Milovanov studies c) faithful agreement of Tsallis non
equilibrium statistical theory with the experimental estimations of i)
non-Gaussian probability distribution function, ii) multifractal scaling
exponent spectrum and generalized Renyi dimension spectrum, iii) exponent
spectrum of the structure functions estimated for the sunspot index and its
underlying non equilibrium solar dynamics.Comment: 40 pages, 11 figure
Time--delay autosynchronization of the spatio-temporal dynamics in resonant tunneling diodes
The double barrier resonant tunneling diode exhibits complex spatio-temporal
patterns including low-dimensional chaos when operated in an active external
circuit. We demonstrate how autosynchronization by time--delayed feedback
control can be used to select and stabilize specific current density patterns
in a noninvasive way. We compare the efficiency of different control schemes
involving feedback in either local spatial or global degrees of freedom. The
numerically obtained Floquet exponents are explained by analytical results from
linear stability analysis.Comment: 10 pages, 16 figure
A discontinuous extended Kalman filter for non-smooth dynamic problems
Problems that result into locally non-differentiable and hence non-smooth state-space equations are often encountered in engineering. Examples include problems involving material laws pertaining to plasticity, impact and highly non-linear phenomena. Estimating the parameters of such systems poses a challenge, particularly since the majority of system identification algorithms are formulated on the basis of smooth systems under the assumption of observability, identifiability and time invariance. For a smooth system, an observable state remains observable throughout the system evolution with the exception of few selected realizations of the state vector. However, for a non-smooth system the observable set of states and parameters may vary during the evolution of the system throughout a dynamic analysis. This may cause standard identification (ID) methods, such as the Extended Kalman Filter, to temporarily diverge and ultimately fail in accurately identifying the parameters of the system. In this work, the influence of observability of non-smooth systems to the performance of the Extended and Unscented Kalman Filters is discussed and a novel algorithm particularly suited for this purpose, termed the Discontinuous Extended Kalman Filter (DEKF), is proposed
Clinical and neuroanatomical signatures of tissue pathology in frontotemporal lobar degeneration.
Identification of a RAI1-associated disease network through integration of exome sequencing, transcriptomics, and 3D genomics.
Smith-Magenis syndrome (SMS) is a developmental disability/multiple congenital anomaly disorder resulting from haploinsufficiency of RAI1. It is characterized by distinctive facial features, brachydactyly, sleep disturbances, and stereotypic behaviors.
We investigated a cohort of 15 individuals with a clinical suspicion of SMS who showed neither deletion in the SMS critical region nor damaging variants in RAI1 using whole exome sequencing. A combination of network analysis (co-expression and biomedical text mining), transcriptomics, and circularized chromatin conformation capture (4C-seq) was applied to verify whether modified genes are part of the same disease network as known SMS-causing genes.
Potentially deleterious variants were identified in nine of these individuals using whole-exome sequencing. Eight of these changes affect KMT2D, ZEB2, MAP2K2, GLDC, CASK, MECP2, KDM5C, and POGZ, known to be associated with Kabuki syndrome 1, Mowat-Wilson syndrome, cardiofaciocutaneous syndrome, glycine encephalopathy, mental retardation and microcephaly with pontine and cerebellar hypoplasia, X-linked mental retardation 13, X-linked mental retardation Claes-Jensen type, and White-Sutton syndrome, respectively. The ninth individual carries a de novo variant in JAKMIP1, a regulator of neuronal translation that was recently found deleted in a patient with autism spectrum disorder. Analyses of co-expression and biomedical text mining suggest that these pathologies and SMS are part of the same disease network. Further support for this hypothesis was obtained from transcriptome profiling that showed that the expression levels of both Zeb2 and Map2k2 are perturbed in Rai1 (-/-) mice. As an orthogonal approach to potentially contributory disease gene variants, we used chromatin conformation capture to reveal chromatin contacts between RAI1 and the loci flanking ZEB2 and GLDC, as well as between RAI1 and human orthologs of the genes that show perturbed expression in our Rai1 (-/-) mouse model.
These holistic studies of RAI1 and its interactions allow insights into SMS and other disorders associated with intellectual disability and behavioral abnormalities. Our findings support a pan-genomic approach to the molecular diagnosis of a distinctive disorder
Phenomenology of the Lense-Thirring effect in the Solar System
Recent years have seen increasing efforts to directly measure some aspects of
the general relativistic gravitomagnetic interaction in several astronomical
scenarios in the solar system. After briefly overviewing the concept of
gravitomagnetism from a theoretical point of view, we review the performed or
proposed attempts to detect the Lense-Thirring effect affecting the orbital
motions of natural and artificial bodies in the gravitational fields of the
Sun, Earth, Mars and Jupiter. In particular, we will focus on the evaluation of
the impact of several sources of systematic uncertainties of dynamical origin
to realistically elucidate the present and future perspectives in directly
measuring such an elusive relativistic effect.Comment: LaTex, 51 pages, 14 figures, 22 tables. Invited review, to appear in
Astrophysics and Space Science (ApSS). Some uncited references in the text
now correctly quoted. One reference added. A footnote adde
Ciências sociais e ambientais rural: principais temas e perspectivas analíticas.
Este trabalho tem por finalidade fazer um balanço dos estudos ambientais rurais sob a perspectiva das ciências sociais. Para isso, em primeiro lugar, realiza-se uma análise da trajetória dos movimentos sociais, identificando-se as principais questões ambientais emergentes na ótica dos atores do mundo rural. Num segundo momento, agrupam-se os temas privilegiados pelos pesquisadores para, em seguida, apontar as principais perspectivas analíticas em curso
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