Econometric modelling of enterprise financial activity

The article considers specific features of application of vector auto-regression technologies and models of error correcting in the study of strategic financial position of an enterprise. It offers an algorithm of selection of the method of forecasting interconnected financial indicators. It develops dynamic systems of indicators of external and internal financial environment of an enterprise. The obtained results could be used in strategic management of the enterprise financial activity

ЗАВИСИМОСТЬ УСПЕШНОСТИ ПРОХОЖДЕНИЯ АЛЬФА-ТРЕНИНГА ОТ ЭКСТРАВЕРСИИ И НЕЙРОТИЗМА

The present paper shows the relationship of the success rate of alpha-training – learning to voluntarily increase the power of the alpha-rhythm with the help of the neurofeedback – with factors of the "Big Five" model of personality traits (NEO–FFI). It was found that most successful at the task of training were the subjects with low scores on Extraversion dimension and moderately high scores on Neuroticism dimension.Показана связь успешности прохождения альфа-тренинга – обучения произвольному увеличению мощности альфа-ритма при помощи технологии биоуправления – с факторами «большой пятерки» личностных черт (NEO-FFI). Установлено, что c задачей тренинга наиболее успешно справляются испытуемые с низкими баллами по шкале «Экстраверсия» и умеренно высокими баллами по шкале «Нейротизм»

Numerical Investigation into the Effect of Splats and Pores on the Thermal Fracture of Air Plasma-Sprayed Thermal Barrier Coatings

The effect of splat interfaces on the fracture behavior of air plasma-sprayed thermal barrier coatings (APS-TBC) is analyzed using finite element modeling involving cohesive elements. A multiscale approach is adopted in which the explicitly resolved top coat microstructural features are embedded in a larger domain. Within the computational cell, splat interfaces are modeled as being located on a sinusoidal interface in combination with a random distribution of pores. Parametric studies are conducted for different splat interface waviness, spacing, pore volume fraction and fracture properties of the splat interface. The results are quantified in terms of crack nucleation temperature and total microcrack length. It is found that the amount of cracking in TBCs actually decreases with increased porosity up to a critical volume fraction. In contrast, the presence of splats is always detrimental to the TBC performance. This detrimental effect is reduced for the splat interfaces with high waviness and spacing compared to those with low waviness and spacing. The crack initiation temperature was found to be linearly dependent on the normal fracture properties of the splat interface. Insights derived from the numerical results aid in engineering the microstructure of practical TBC systems for improved resistance against thermal fracture

Results of the work of Yekaterinburg city cardiorheumatological child center and the possibility of specialized medical care today

The article presents the history and the work of City Cardiorheumatological Child Center which is located in the Children`s Clinical Hospital №11 Yekaterinburg City. The characteristic of the work of all departments of cardiorheumatological center, which includes outpatient advisory department (10,800 visits per year), cardiorheumatological department, day hospital, intensive care unit, functional diagnostics department with ultrasound procedures presented. Organization of such structures of pediatric service can improve the efficiency of diagnosis and treatment cardiac disease in young age.В статье представлена история создания городского детского кардиологического центра и современная модель центра на базе ДГКБ №11. и кафедры поликлинической педиатрии и педиатрии ФПК и ПП Уральского Государственного медицинского Университета. Дана характеристика работы всех подразделений кардиоревматологического центра, включающего специализированное отделение, амбулаторно-консультативное отделение на 10,8 тысяч посещений в год, дневной стационар, отделение реанимации и интенсивной терапии и отделение функциональной диагностики с кабинетом УЗИ-исследований. Организация подобных структур педиатрической службы позволяет повышать эффективность диагностики и лечения детей с кардиологической патологией и предупредить прогрессирование в молодом и более старшем возрасте

Transcriptional responses of winter barley to cold indicate nucleosome remodelling as a specific feature of crown tissues

We report a series of microarray-based comparisons of gene expression in the leaf and crown of the winter barley cultivar Luxor, following the exposure of young plants to various periods of low (above and below zero) temperatures. A transcriptomic analysis identified genes which were either expressed in both the leaf and crown, or specifically in one or the other. Among the former were genes responsible for calcium and abscisic acid signalling, polyamine synthesis, late embryogenesis abundant proteins and dehydrins. In the crown, the key organ for cereal overwintering, cold treatment induced transient changes in the transcription of nucleosome assembly genes, and especially H2A and HTA11, which have been implicated in cold sensing in Arabidopsis thaliana. In the leaf, various heat-shock proteins were induced. Differences in expression pattern between the crown and leaf were frequent for genes involved in certain pathways responsible for osmolyte production (sucrose and starch, raffinose, γ-aminobutyric acid metabolism), sugar signalling (trehalose metabolism) and secondary metabolism (lignin synthesis). The action of proteins with antifreeze activity, which were markedly induced during hardening, was demonstrated by a depression in the ice nucleation temperature

Medroxyprogesterone Acetate Alters Mycobacterium Bovis BCG-Induced Cytokine Production in Peripheral Blood Mononuclear Cells of Contraceptive Users

Most individuals latently infected with Mycobacterium tuberculosis (M.tb) contain the infection by a balance of effector and regulatory immune responses. This balance can be influenced by steroid hormones such as glucocorticoids. The widely used contraceptive medroxyprogesterone acetate (MPA) possesses glucocorticoid activity. We investigated the effect of this hormone on immune responses to BCG in household contacts of active TB patients. Multiplex bead array analysis revealed that MPA demonstrated both glucocorticoid and progestogenic properties at saturating and pharmacological concentrations in peripheral blood mononuclear cells (PBMCs) and suppressed antigen specific cytokine production. Furthermore we showed that PBMCs from women using MPA produced significantly lower levels of IL-1α, IL-12p40, IL-10, IL-13 and G-CSF in response to BCG which corresponded with lower numbers of circulating monocytes observed in these women. Our research study is the first to show that MPA impacts on infections outside the genital tract due to a systemic effect on immune function. Therefore MPA use could alter susceptibility to TB, TB disease severity as well as change the efficacy of new BCG-based vaccines, especially prime-boost vaccine strategies which may be administered to adult or adolescent women in the future

Innovative direction of educational trajectory of pediatrics under continuous medical education successes, problems and prospects

The main problems and perspectives of the development of continuous medical education (NMI) and the work of the Department of Polyclinic Pediatrics and Pediatrics of the FPK and PP FGBOU in the UGMU of the Ministry of Health of Russia on the introduction of the NMA system are presented. An analysis of the results of the questionnaire survey of 45 pediatricians participating in the implementation of the pilot project for the implementation of the additional educational program “Palliative care in pediatrics.” As a result of the study, 80% of the practitioners indicated that the information on the palliative care system for children is known to them for the first time, and the cycle is timely and in demand by the pediatric community.Представлены основные проблемы и перспективы развития непрерывного медицинского образования (НМО) и работа кафедры поликлинической педиатрии и педиатрии ФПК и ПП ФГБОУ ВО УГМУ Минздрава России по внедрению системы НМО. Проведен анализ результатов анкетирования 45 врачей-педиатров, участвующих в реализации пилотного проекта по реализации дополнительной образовательной программы «Паллиативная помощь в педиатрии». В результате проведенного исследования 80% врачей практического звена указали на то, что полученная информация по системе оказания паллиативной помощи детям познается ими впервые, а проведение цикла своевременно и востребовано педиатрическим сообществом

Fructan and its relationship to abiotic stress tolerance in plants

Numerous studies have been published that attempted to correlate fructan concentrations with freezing and drought tolerance. Studies investigating the effect of fructan on liposomes indicated that a direct interaction between membranes and fructan was possible. This new area of research began to move fructan and its association with stress beyond mere correlation by confirming that fructan has the capacity to stabilize membranes during drying by inserting at least part of the polysaccharide into the lipid headgroup region of the membrane. This helps prevent leakage when water is removed from the system either during freezing or drought. When plants were transformed with the ability to synthesize fructan, a concomitant increase in drought and/or freezing tolerance was confirmed. These experiments indicate that besides an indirect effect of supplying tissues with hexose sugars, fructan has a direct protective effect that can be demonstrated by both model systems and genetic transformation

Session 17 Ecophysiology

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