2,531 research outputs found
The transmission of nosocomial pathogens in an intensive care unit: a space–time clustering and structural equation modelling approach
We investigated the incidence of cases of nosocomial pathogens and risk factors in an intensive treatment unit ward to determine if the number of cases is dependent on location of patients and the colonization/infection history of the ward. A clustering approach method was developed to investigate the patterns of spread of cases through time for five microorganisms [methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter spp., Klebsiella spp., Candida spp., and Pseudomonas aeruginosa] using hospital microbiological monitoring data and ward records of patient-bed use. Cases of colonization/infection by MRSA, Candida and Pseudomonas were clustered in beds and through time while cases of Klebsiella and Acinetobacter were not. We used structural equation modelling to analyse interacting risk factors and the potential pathways of transmission in the ward. Prior nurse contact with colonized/infected patients, mediated by the number of patient-bed movements, were important predictors for all cases, except for those of Pseudomonas. General health and invasive surgery were significant predictors of cases of Candida and Klebsiella. We suggest that isolation and bed movement as a strategy to manage MRSA infections is likely to impact upon the incidence of cases of other opportunist pathogen
Cluster Ellipticities as a Cosmological Probe
We investigate the dependence of ellipticities of clusters of galaxies on
cosmological parameters using large-scale cosmological simulations. We
determine cluster ellipticities out to redshift unity for LCDM models with
different mean densities and amplitudes of mass fluctuation
. The mean ellipticity increases monotonically with redshift for
all models. Larger values of , i.e., earlier cluster formation
time, produce lower ellipticities. The dependence of ellipticity on
is relatively weak in the range for high mass
clusters. The mean ellipticity decreases linearly with the
amplitude of fluctuations at the cluster redshift , nearly independent of
; on average, older clusters are more relaxed and are thus less
elliptical. The distribution of ellipticities about the mean is approximated by
a Gaussian, allowing a simple characterization of the evolution of ellipticity
with redshift as a function of cosmological parameters. At , the mean
ellipticity of high mass clusters is approximated by . This relation opens up the
possibility that, when compared with future observations of large cluster
samples, the mean cluster ellipticity and its evolution could be used as a new,
independent tool to constrain cosmological parameters, especially the amplitude
of mass fluctuations, .Comment: 16 pages, 4 figure
Seguimiento de poblaciones con baja densidad: una perspectiva de qué nivel de declive poblacional podemos detectar con certeza
Monitoring of mammal species is an important part in detecting changes in their status. Efforts are based
on a variety of direct and indirect methods and many low density populations are monitored through field
signs. We present data on the endangered European red squirrel from Kidland Forest in the UK. We used
cone transects to both record changes in seed availability and to monitor population trends. We examined the difficulty of accurately detecting population change when populations are low and field signs are patchily distributed. Current efforts would be sufficient to detect significant population declines of 50–75% in years with a modest squirrel population but not when they fall below one squirrel for every 20 ha of forest. The findings emphasise that monitoring aims have to be clearly defined with an awareness and understanding of what level of change the adopted methodological approach can reliably detect. We propose that mammal monitoring schemes need to be based on a pilot scheme to determine effect size and planned accordingly.
Key words: Squirrel, Sciurus vulgaris, Conservation, Power analysis.El seguimiento de las especies de mamÃferos es una parte importante de la detección de los cambios producidos en su estatus. Los esfuerzos van dirigidos hacia diversos métodos directos e indirectos, y muchas poblaciones que presentan una densidad baja se monitorizan mediante rastros o signos de campo. En este trabajo presentamos datos de una especie en peligro, la ardilla roja, del bosque de Kidland en el Reino Unido. Se realizaron transectos de detección de piñas o conos para registrar tanto los cambios en la disponibilidad de semillas como para monitorizar las tendencias de la población. Examinamos la dificultad que presenta detectar con precisión los cambios poblacionales, cuando las poblaciones son pequeñas y los restos alimentarios de presencia están distribuidos de forma desigual. Los esfuerzos normales deberÃan ser suficientes para detectar disminuciones poblacionales significativas del 50–75% en años con una población de ardillas modesta, pero no cuando la densidad está por debajo de una ardilla cada 20 ha de bosque. Nuestros hallazgos enfatizan que los esfuerzos de seguimiento deben estar claramente definidos, con el conocimiento y la comprensión de qué nivel de cambio puede realmente detectar de forma fiable el enfoque metodológico adoptado. Proponemos que los seguimientos de mamÃferos deben estar basados en un esquema piloto, con el fin de determinar el efecto del tamaño, y ser planificados consecuentemente.
Palabras clave: Ardilla, Sciurus vulgaris, Conservación, Análisis de potencia
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Advancing Pharmacist Collaborative Care within Academic Health Systems.
INTRODUCTION:The scope of pharmacy practice has evolved over the last few decades to focus on the optimization of medication therapy. Despite this positive impact, the lack of reimbursement remains a significant barrier to the implementation of innovative pharmacist practice models. SUMMARY:We describe the successful development, implementation and outcomes of three types of pharmacist collaborative care models: (1) a pharmacist with physician oversight, (2) pharmacist-interprofessional teams and (3) physician-pharmacist teams. The outcome measurement of these pharmacist care models varied from the design phase to patient volume measurement and to comprehensive quality dashboards. All of these practice models have been successfully funded by affiliated health systems or grants. CONCLUSIONS:The expansion of pharmacist services delivered by clinical faculty has several benefits to affiliated health systems: (1) significant improvements in patient care quality, (2) access to experts in specialty areas, and (3) the dissemination of outcomes with national and international recognition, increasing the visibility of the health system
Time independent description of rapidly oscillating potentials
The classical and quantum dynamics in a high frequency field are found to be
described by an effective time independent Hamiltonian. It is calculated in a
systematic expansion in the inverse of the frequency () to order
. The work is an extension of the classical result for the Kapitza
pendulum, which was calculated in the past to order . The analysis
makes use of an implementation of the method of separation of time scales and
of a quantum gauge transformation in the framework of Floquet theory. The
effective time independent Hamiltonian enables one to explore the dynamics in
presence of rapidly oscillating fields, in the framework of theories that were
developed for systems with time independent Hamiltonians. The results are
relevant, in particular, for exploration of the dynamics of cold atoms.Comment: 4 pages, 1 figure. Revised versio
Floquet states and persistent currents transitions in a mesoscopic ring
We consider the effect of an oscillating potential on the single-particle
spectrum and the time-averaged persistent current of a one-dimensional
phase-coherent mesoscopic ring with a magnetic flux. We show that in a ring
with an even number of spinless electrons the oscillating potential has a
strong effect on the persistent current when the excited side bands are close
to the eigen levels of a pure ring. Resonant enhancement of side bands of the
Floquet state generates a sign change of the persistent current.Comment: 2 figure
Resonant Auger spectroscopy at the L2,3 shake-up thresholds as a probe of electron correlation effects in nickel
The excitation energy dependence of the three-hole satellites in the
L3-M4,5M4,5 and L2-M4,5M4,5 Auger spectra of nickel metal has been measured
using synchrotron radiation. The satellite behavior in the non-radiative
emission spectra at the L3 and L2 thresholds is compared and the influence of
the Coster-Kronig channel explored. The three-hole satellite intensity at the
L3 Auger emission line reveals a peak structure at 5 eV above the L3 threshold
attributed to resonant processes at the 2p53d9 shake-up threshold. This is
discussed in connection with the 6-eV feature in the x-ray absorption spectrum.Comment: 8 pages, 4 figures; http://prb.aps.org/abstract/PRB/v58/i7/p3677_
Anharmonic double-phonon excitations in the interacting boson model
Double- vibrations in deformed nuclei are analyzed in the context of
the interacting boson model. A simple extension of the original version of the
model towards higher-order interactions is required to explain the observed
anharmonicities of nuclear vibrations. The influence of three- and four-body
interactions on the moments of inertia of ground- and -bands, and on
the relative position of single- and double- bands is studied
in detail. As an example of a realistic calculation, spectra and transitions of
the highly -anharmonic nuclei Dy, Er, and Er
are interpreted in this approach.Comment: 38 pages, TeX (ReVTeX). 15 ps figures. Submitted to Phys. Rev.
Phase diffusion as a model for coherent suppression of tunneling in the presence of noise
We study the stabilization of coherent suppression of tunneling in a driven
double-well system subject to random periodic function ``kicks''. We
model dissipation due to this stochastic process as a phase diffusion process
for an effective two-level system and derive a corresponding set of Bloch
equations with phase damping terms that agree with the periodically kicked
system at discrete times. We demonstrate that the ability of noise to localize
the system on either side of the double-well potenital arises from overdamping
of the phase of oscillation and not from any cooperative effect between the
noise and the driving field. The model is investigated with a square wave
drive, which has qualitatively similar features to the widely studied
cosinusoidal drive, but has the additional advantage of allowing one to derive
exact analytic expressions.Comment: 17 pages, 4 figures, submitted to Phys. Rev.
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