20 research outputs found

    Le parcours de vie d'adultes exposés à la violence conjugale dans leur enfance ou leur adolescence : une étude rétrospective

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    La prĂ©sente recherche s’intĂ©resse aux parcours de vie d’adultes ayant Ă©tĂ© victimes d’exposition Ă  la violence conjugale (EVC) dans leur enfance ou leur adolescence. Cette Ă©tude a pour objectifs de : 1) mieux comprendre les effets perçus de l’EVC sur les diffĂ©rentes trajectoires de vie d’adultes ayant vĂ©cu cette victimisation, et ce, tout au long de la vie des individus; 2) d’explorer, auprĂšs de ces adultes, les liens qu’ils perçoivent entre cette victimisation, les autres expĂ©riences vĂ©cues dans les diffĂ©rentes trajectoires de vie ainsi que les facteurs aidants dans leur parcours. L’approche qualitative et descriptive de l’étude permet de donner la parole aux personnes directement concernĂ©es. Afin de rĂ©pondre aux objectifs de la recherche, une approche mixte a Ă©tĂ© utilisĂ©e. Un questionnaire en ligne quantitatif visant Ă  mesurer l’ensemble des victimisations subies incluant l’EVC et une entrevue individuelle qualitative ont Ă©tĂ© rĂ©alisĂ©s avec les neuf participants Ă  l’étude. Les donnĂ©es quantitatives ont Ă©tĂ© analysĂ©es de maniĂšre descriptive Ă  l’aide du logiciel SPSS et ont aussi servi Ă  orienter les questions pertinentes Ă  explorer dans l’entrevue qualitative. Les transcriptions des donnĂ©es qualitatives ont Ă©tĂ© codifiĂ©es et analysĂ©es avec le logiciel N’Vivo. L’analyse des transcriptions a rĂ©vĂ©lĂ© que les participants considĂšrent que l’EVC qu’ils ont vĂ©cue dans leur enfance a eu des impacts et des rĂ©percussions sur leurs diffĂ©rentes trajectoires de vie, et ce, mĂȘme rendu Ă  l’ñge adulte. Des problĂšmes de santĂ© mentale, de la difficultĂ© Ă  entrer en relation avec d’autres gens, la transmission intergĂ©nĂ©rationnelle de la victimisation et de la violence et la polyvictimisation ont Ă©tĂ© nommĂ©s comme des consĂ©quences de l’exposition. Des facteurs aidants tels que du soutien informel, des services d’aide formels parfois dans l’enfance mais surtout Ă  l’ñge adulte, leurs caractĂ©ristiques personnelles ainsi que leurs stratĂ©gies ont permis aux participants de passer Ă  travers les violences vĂ©cues

    Young adults’ viewpoints concerning helpful factors when living in an intimate partner violence context

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    This qualitative study examined factors which were considered to be helpful by young adults who were exposed to intimate partner violence (IPV) during their childhood and adolescence. Life course theory was chosen for the analysis framework because it allowed us to look at the factors found in such diverse trajectories as family, friendship, romantic relationships, school, and work. The sample was comprised of 45 young Qu®ebec adults from 18 to 25 years old who were exposed to IPV. The participants began by filling out an online questionnaire documenting their victimization experiences (the Adult Retrospective Version of the Juvenile Victimization Questionnaire). They then participated in a semi-structured interview based on their own life history calendar. The results indicated five main types of helpful factors: 1) emotional support, 2) material help, 3) professional help, 4) distancing strategies, and 5) opportunities to experience success and discover one’s strengths and abilities. Certain factors were noted in most of the above-mentioned trajectories, whereas others were specific to one or a few trajectories. In conclusion, the need to conduct further research on protective factors is emphasized, with the goal being to improve interventions with young people exposed to IPV and with those close to them, and to positively influence their life courses

    Exposure to intimate partner violence : perceived links with other victimizations and the severity of violence by young adults in Québec

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    The objective of this qualitative study was to understand how young adults (18 - 25 years old) who were exposed to intimate partner violence (IPV) during childhood and adolescence explained the links between this violence and the other victimizations that they had experienced, as well as the perceived severity that they assigned to these victimizations. The participants (N = 45) were recruited in the Province of Quebec (Canada). Before the interview, they filled out an online questionnaire with the Adult Retrospective Version of the Juvenile Victimization Questionnaire as well as answering sociodemographic questions. They likewise noted the victimization to which they were subjected before they reached adulthood. These data helped us to better prepare the qualitative interviews, allowing us to explore the links the youth see or do not see between their exposure to IPV and other declared victimizations. Interviews lasted an average of two hours and were supported by a semi-structured interview guide and a life history calendar. The results show that many of the participants identified stronger links between exposure to IPV and child maltreatment, intimidation at school, and dating violence. Findings highlight the importance of considering youth’s viewpoints about the victimizations they suffer so as to develop intervention and prevention programs that are better adapted to these youth’s experiences and point of views

    Mieux rĂ©pondre aux besoins complexes des familles confrontĂ©es Ă  la cooccurrence de violence conjugale et d’un problĂšme de santĂ© mentale ou de consommation

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    Cette recherche qualitative explore les points de vue de mĂšres, de pĂšres et d’adolescents (n = 43) quant aux services reçus pour les problĂšmes cooccurrents de violence conjugale, de santĂ© mentale et de consommation chez les parents. Les donnĂ©es ont Ă©tĂ© recueillies par des entrevues semi-dirigĂ©es, soutenues d’un outil de cartographie des services utilisĂ©s. L’analyse de contenu thĂ©matique montre que les participants dĂ©ploient plusieurs stratĂ©gies pour faire face aux problĂšmes cooccurrents vĂ©cus et utilisent diverses ressources d’aide formelle et informelle. Plusieurs recommandations sont proposĂ©es pour amĂ©liorer l’offre d’aide aux familles en situation de cooccurrence, dont la concertation entre les diffĂ©rentes ressources concernĂ©es.This qualitative research explores the point of views of mothers, fathers, and teenagers (n = 43) about the services they received for co-occurring problems of intimate partner violence, mental health, and parental substance use. The data were collected through semi-structured interviews, supported by a mapping tool of the services they used. The thematic content analysis shows that participants deploy several strategies to address co-occurring problems and use various formal and informal support resources. Several recommendations are proposed to improve the offer of assistance to families in situations of co-occurrence, including concertation between the different concerned resources

    L’influence perçue de l’exposition Ă  la violence conjugale sur les relations significatives des jeunes concernĂ©s : une perspective temporelle

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    Cadre de la recherche : Cet article porte sur l’évolution des relations avec les personnes significatives pour les jeunes adultes ayant Ă©tĂ© exposĂ©s Ă  de la violence conjugale pendant leur enfance ou leur adolescence. Objectifs : Cette recherche vise Ă  identifier les personnes ayant eu une influence importante dans le parcours de vie des jeunes concernĂ©s, Ă  examiner comment les relations avec ces personnes significatives ont Ă©voluĂ© Ă  travers le temps et dans quelle mesure l’exposition Ă  la violence conjugale a influencĂ© ces relations. MĂ©thodologie : Il s’agit d’une recherche qualitative fondĂ©e sur la thĂ©orie des parcours de vie. Nous avons rĂ©alisĂ© des entrevues semi-structurĂ©es, soutenues par l’outil du calendrier historique de vie, auprĂšs de 45 jeunes de 18 Ă  25 ans. RĂ©sultats : L’exposition Ă  la violence conjugale affecte de façon plus importante les relations avec les parents, bien que de façon diffĂ©rente avec le parent qui exerce la violence qu’avec celui qui la subit. Les relations avec les autres personnes significatives (amis, fratrie, famille Ă©largie, autres) tendent Ă  ĂȘtre plus stables dans le temps, sont gĂ©nĂ©ralement aidantes et fluctuent moins en fonction de l’exposition Ă  la violence conjugale que les relations parent(s)-enfant(s). Les relations amoureuses, quant Ă  elles, impliquent parfois une revictimisation, mais sont aussi des occasions de reconstruire des relations plus saines et Ă©galitaires. Conclusions : Cette recherche contribue au dĂ©veloppement des connaissances sur les relations significatives pour les jeunes ayant Ă©tĂ© exposĂ©s Ă  de la violence conjugale. La perspective d’analyse temporelle que nous avons privilĂ©giĂ©e permet de souligner les angles morts des recherches rĂ©alisĂ©es Ă  ce jour et de proposer des pistes de recherche futures. Contribution : Cette recherche suggĂšre des pistes d’amĂ©lioration de l’aide offerte aux jeunes concernĂ©s et Ă  leurs proches, en mobilisant davantage les relations qu’ils identifient comme significatives dans leurs diffĂ©rentes trajectoires de vie – familiale, amicale, amoureuse, scolaire et professionnelle.Research Framework: This article examines the evolution of relationships identified as significant by young adults who were exposed to intimate partner violence in childhood or adolescence. Objectives: The study attempted to identify the people who had an important influence on the young people’s life course, to examine how the relationships with these significant people evolved, and to determine the extent to which exposure to intimate partner violence influenced these relationships. Methodology: This is a qualitative study based on life course theory. Semi-structured interviews, accompanied by a life-course calendar, were conducted with 45 persons from 18 to 25 years old. Results: Exposure to intimate partner violence had a greater impact on the relationships with the parents, although in different ways which depended on whether it was the parent who perpetrated or who was subjected to the violence. The relationships with other significant people (friends, siblings, extended family, etc.) tended to be more stable over time and were generally supportive and fluctuated less in the presence of intimate partner violence. Dating relationships sometimes led to a revictimization but also represented occasions to rebuild healthier and more equal relationships. Conclusions: This study contributes to our understanding of the significant relationships of young people who have been exposed to intimate partner violence. The temporal analysis perspective adopted here helped to identify some of the shortcomings in previous studies and to propose avenues for future research. Contribution: This study suggests certain actions to improve aid provided for youths and those close to them. The aim is to take advantage of the relationships that they consider significant in their various life trajectories, namely family, friends, intimate partner, school, and work

    Challenges in mathematical cognition: a collaboratively-derived research agenda

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    This paper reports on a collaborative exercise designed to generate a coherent agenda for research on mathematical cognition. Following an established method, the exercise brought together 16 mathematical cognition researchers from across the fields of mathematics education, psychology and neuroscience. These participants engaged in a process in which they generated an initial list of research questions with the potential to significantly advance understanding of mathematical cognition, winnowed this list to a smaller set of priority questions, and refined the eventual questions to meet criteria related to clarity, specificity and practicability. The resulting list comprises 26 questions divided into six broad topic areas: elucidating the nature of mathematical thinking, mapping predictors and processes of competence development, charting developmental trajectories and their interactions, fostering conceptual understanding and procedural skill, designing effective interventions, and developing valid and reliable measures. In presenting these questions in this paper, we intend to support greater coherence in both investigation and reporting, to build a stronger base of information for consideration by policymakers, and to encourage researchers to take a consilient approach to addressing important challenges in mathematical cognition

    Challenges in Mathematical Cognition: A Collaboratively-Derived Research Agenda

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    This paper reports on a collaborative exercise designed to generate a coherent agenda for research on mathematical cognition. Following an established method, the exercise brought together 16 mathematical cognition researchers from across the fields of mathematics education,psychology and neuroscience. These participants engaged in a process in which they generated an initial list of research questions with the potential to significantly advance understanding of mathematical cognition, winnowed this list to a smaller set of priority questions, and refined the eventual questions to meet criteria related to clarity, specificity and practicability. The resulting list comprises 26 questions divided into sixbroad topic areas: elucidating the nature of mathematical thinking, mapping predictors and processes of competence development, charting developmental trajectories and their interactions, fostering conceptual understanding and procedural skill, designing effective interventions, and developing valid and reliable measures. In presenting these questions in this paper, we intend to support greater coherence in both investigation and reporting, to build a stronger base of information for consideration by policymakers, and to encourage researchers to take a consilient approach to addressing important challenges in mathematical cognition.</p

    Mitochondrial genetic diversity, selection and recombination in a canine transmissible cancer.

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    Canine transmissible venereal tumour (CTVT) is a clonally transmissible cancer that originated approximately 11,000 years ago and affects dogs worldwide. Despite the clonal origin of the CTVT nuclear genome, CTVT mitochondrial genomes (mtDNAs) have been acquired by periodic capture from transient hosts. We sequenced 449 complete mtDNAs from a global population of CTVTs, and show that mtDNA horizontal transfer has occurred at least five times, delineating five tumour clades whose distributions track two millennia of dog global migration. Negative selection has operated to prevent accumulation of deleterious mutations in captured mtDNA, and recombination has caused occasional mtDNA re-assortment. These findings implicate functional mtDNA as a driver of CTVT global metastatic spread, further highlighting the important role of mtDNA in cancer evolution.Wellcome Trust Investigator Award, 102942/Z/13/A Elizabeth P Murchison Leverhulme Trust Philip Leverhulme Prize Elizabeth P Murchison Royal Society Research Grant, RG130615 Elizabeth P Murchiso

    Recurrent horizontal transfer identifies mitochondrial positive selection in a transmissible cancer

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    Abstract: Autonomous replication and segregation of mitochondrial DNA (mtDNA) creates the potential for evolutionary conflict driven by emergence of haplotypes under positive selection for ‘selfish’ traits, such as replicative advantage. However, few cases of this phenomenon arising within natural populations have been described. Here, we survey the frequency of mtDNA horizontal transfer within the canine transmissible venereal tumour (CTVT), a contagious cancer clone that occasionally acquires mtDNA from its hosts. Remarkably, one canine mtDNA haplotype, A1d1a, has repeatedly and recently colonised CTVT cells, recurrently replacing incumbent CTVT haplotypes. An A1d1a control region polymorphism predicted to influence transcription is fixed in the products of an A1d1a recombination event and occurs somatically on other CTVT mtDNA backgrounds. We present a model whereby ‘selfish’ positive selection acting on a regulatory variant drives repeated fixation of A1d1a within CTVT cells

    Somatic evolution and global expansion of an ancient transmissible cancer lineage

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    Made available in DSpace on 2019-10-06T15:53:36Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-08-02GPD Charitable TrustLeverhulme TrustThe canine transmissible venereal tumor (CTVT) is a cancer lineage that arose several millennia ago and survives by “metastasizing” between hosts through cell transfer. The somatic mutations in this cancer record its phylogeography and evolutionary history. We constructed a time-resolved phylogeny from 546 CTVT exomes and describe the lineage's worldwide expansion. Examining variation in mutational exposure, we identify a highly context-specific mutational process that operated early in the cancer's evolution but subsequently vanished, correlate ultraviolet-light mutagenesis with tumor latitude, and describe tumors with heritable hyperactivity of an endogenous mutational process. CTVT displays little evidence of ongoing positive selection, and negative selection is detectable only in essential genes. We illustrate how long-lived clonal organisms capture changing mutagenic environments, and reveal that neutral genetic drift is the dominant feature of long-term cancer evolution.Transmissible Cancer Group Department of Veterinary Medicine University of CambridgeAnimal Management in Rural and Remote Indigenous Communities (AMRRIC)World VetsAnimal Shelter Stichting Dierenbescherming SurinameSikkim Anti-Rabies and Animal Health Programme Department of Animal Husbandry Livestock Fisheries and Veterinary Services Government of SikkimRoyal (Dick) School of Veterinary Studies Roslin Institute University of Edinburgh Easter Bush CampusConserLab Animal Preventive Medicine Department Faculty of Animal and Veterinary Sciences University of ChileCorozal Veterinary Hospital University of PanamĂĄSt. George's UniversityNakuru District Veterinary Scheme LtdAnimal Medical CentreInternational Animal Welfare Training Institute UC Davis School of Veterinary MedicineCentro UniversitĂĄrio de Rio Preto (UNIRP)Department of Clinical and Veterinary Surgery SĂŁo Paulo State University (UNESP)Ladybrand Animal ClinicVeterinary Clinic Sr. Dog'sWorld Vets Latin America Veterinary Training CenterNational Veterinary Research InstituteAnimal ClinicIntermunicipal Stray Animals Care Centre (DIKEPAZ)Animal Protection Society of SamoaFaculty of Veterinary Science University of ZuliaVeterinary Clinic BIOCONTROLFaculty of Veterinary Medicine School of Health Sciences University of ThessalyVeterinary Clinic El Roble Animal Healthcare Network Faculty of Animal and Veterinary Sciences University of ChileOnevetGroup Hospital VeterinĂĄrio BernaUniversidade Vila VelhaVeterinary Clinic ZoovetservisÉcole Inter-Ă©tats des Sciences et MĂ©decine VĂ©tĂ©rinaires de DakarDepartment of Small Animal Medicine Faculty of Veterinary Medicine Utrecht UniversityVetexpert Veterinary GroupVeterinary Clinic Lopez QuintanaClinique Veterinaire de Grand Fond Saint Gilles les BainsDepartment of Veterinary Sciences University of MessinaFacultad de Medicina Veterinaria y Zootecnia Universidad AutĂłnoma del Estado de MĂ©xicoSchool of Veterinary Medicine Universidad de las AmĂ©ricasCancer Development and Innate Immune Evasion Lab Champalimaud Center for the UnknownTouray and Meyer Vet ClinicHillside Animal HospitalKampala Veterinary SurgeryAsavet Veterinary CharitiesVets Beyond BordersFaculty of Veterinary Medicine Autonomous University of YucatanLaboratorio de PatologĂ­a Veterinaria Universidad de CaldasInterdisciplinary Centre of Research in Animal Health (CIISA) Faculty of Veterinary Medicine University of LisbonFour Paws InternationalHelp in SufferingVeterinary Clinic Dr JosĂ© RojasDepartment of Biotechnology Balochistan University of Information Technology Engineering and Management SciencesCorozal Veterinary ClinicVeterinary Clinic VetmasterState Hospital of Veterinary MedicineJomo Kenyatta University of Agriculture and TechnologyLaboratory of Biomedicine and Regenerative Medicine Department of Clinical Sciences Faculty of Animal and Veterinary Sciences University of ChileFaculty of Veterinary and Agricultural Sciences University of MelbourneAnimal Anti Cruelty LeagueClinical Sciences Department Faculty of Veterinary Medicine BucharestDepartment of Pathology Faculty of Veterinary Medicine Ankara UniversityFaculty of Veterinary Sciences National University of AsuncionLilongwe Society for Protection and Care of Animals (LSPCA)Wellcome Sanger InstituteDepartment of Cellular and Molecular Medicine University of California San DiegoDepartment of Clinical and Veterinary Surgery SĂŁo Paulo State University (UNESP)Leverhulme Trust: 102942/Z/13/
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