Solitary-wave vortices in quadratic nonlinear media

We find families of vortex solitary waves in bulk quadratic nonlinear media under conditions for second-harmonic generation. We show that the vortex solitary waves are azimuthally unstable and that they decay into sets of stable spatial solitons. We calculate the growth rates of the azimuthal perturbations and show how those affect the pattern of output light. © 1998 Optical Society of AmericaPeer ReviewedPostprint (published version

Diseño de un observador y un controlador de velocidad de un motor DC por modos deslizantes

En este artículo se presenta una estructura de estimación y control de estados mediante modos deslizantes para un modelo lineal. Se presenta un sistema mecánico de un Motor DC, al cual se le diseñaran un observador y un controlador deslizante de primer y segundo orden. Los resultados se comparan con un diseño de un PID. Los dos diseños se prueban ante cambios de referencia, perturbaciones y ruido. In this paper a structure for estimation and control of states using sliding modes is presented for a linear model. A mechanical system of a DC motor is presented with a designed observer and a sliding controller of first and second order. The results are compared with a design of a PID. The two designs are tested against reference changes, disturbances and noise. — In this paper a structure for estimation and control of states using sliding modes is presented for a linear model. A mechanical system of a DC motor is presented with a designed observer and a sliding controller of first and second order. The results are compared with a design of a PID. The two designs are tested against reference changes, disturbances and noise. Keywords — Dc Motor, Observer, Sliding modes, State spaceUniversidad Nacional de ColombiaColciencia

Diseño de un Observador y un Controlador de velocidad de un motor DC por modos deslizantes

En este artículo se presenta una estructura de estimación y control de estados implementando las normas básicas de diseño de observadores y controladores mediante modos deslizantes para un modelo lineal. Se presenta un sistema mecánico de un Motor DC, al cual se le diseñaran un observador y un controlador deslizante de primero y segundo orden. Los resultados se comparan con un diseño de un PID. Los dos diseños se prueban ante cambios de referencia, perturbaciones y ruido.Universidad Nacional de ColombiaColcienciasBanco Mundia

Apoyo social formal en colectivos con dificultades de inserción laboral

IX Jornades de Foment de la Investigació de la FCHS (Any 2003-2004

Tipos de lesiones de Piricularia en trigo.

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Solitary-wave Vortices in Quadratic Nonlinear Media

We find families of vortex solitary waves in bulk quadratic nonlinear media under conditions for second-harmonic generation. We show that the vortex solitary waves are azimuthally unstable and that they decay into sets of stable spatial solitons. We calculate the growth rates of the azimuthal perturbations and show how those affect the pattern of output light. © 1998 Optical Society of AmericaThis work has been partially supported by the Spanish Government under grant PB95-0768.Peer Reviewe

Male tilapia production techniques: A mini-review

Tilapia culture has been growing over the past decades as an excellent source of high-quality protein. Some of the Tilapia´s advantages are the ability to breed and produce new generations rapidly, tolerate shallow and turbid waters, resist a high level of disease and be flexible for culture under many different farming systems. These characteristics are the main reasons for its commercial success. However, one of them contributes to the major drawback of pond culture: the high level of uncontrolled reproduction that may occur in grow-out ponds. Uncontrolled reproduction yields to stunted growth and unmar-ketable fish due to offspring competing with the initial stock for food, besides other problems like less dissolved oxygen, greater release of ammonia and feces, heterogeneous sizes and overpopulation stress. Monosex production has been preferred in order to deal with these issues. Males are preferred because they grow almost twice as fast as the females. This paper reviews monosex male production techniques and their results, comprising environment manipulation, hybridization, sex reversal and genetic manipulation. The choice of a particular technique would depend on the legislation of each country. This review’s should help to select the appropriate technique depending on the market target and the commercial technology available.Keywords: Monosex production, hybridization, sex reversal, environmental and genetic sex determinationAfrican Journal of Biotechnology Vol. 12(36), pp. 5496-550

Prevalence of HIV-1 Drug Resistance among Women Screening for HIV Prevention Trials in KwaZulu-Natal, South Africa (MTN-009)

Background:A major concern with using antiretroviral (ARV)-based products for HIV prevention is the potential spread of drug resistance, particularly from individuals who are HIV-infected but unaware of their status. Limited data exist on the prevalence of HIV infection or drug resistance among potential users of ARV-based prevention products.Methods:A cross-sectional study of reproductive-aged women who presented to screen for an HIV prevention trial was conducted at 7 clinical sites in Durban, South Africa. CD4+T cell counts, HIV-1 RNA levels and population sequencing of the protease and reverse transcriptase genes were performed for all women with 2 positive HIV rapid tests. Resistance mutations were identified using the Stanford Calibrated Population Resistance Tool.Results:Of the 1073 evaluable women, 400(37%) were confirmed as HIV-infected. Of those, plasma HIV-1 RNA was detectable in 365/400(91%) and undetectable(200 copies/ml) analyzed for drug resistance, 26(7.4%) had nucleoside reverse transcriptase inhibitor (NRTI), non-nucleoside reverse transcriptase inhibitor (NNRTI) or protease inhibitor (PI) drug resistance mutations. Among those with resistance, 18/26 participants(62%) had single-class NNRTI resistance and 5/26(19%) had dual-class NRTI/NNRTI. Major mutations in reverse transcriptase included K65R(n = 1), L74I(n = 1), K103N(n = 19), V106M(n = 4), Y181C(n = 2), M184V(n = 4), and K219E/R(n = 2). Major PI-resistance mutations were rare: M46L(n = 1) and I85V(n = 1). All participants were infected with subtype C virus, except one infected with subtype A.Conclusions:In women from Durban, South Africa screening for an HIV prevention trial, the HIV prevalence was high (37%) and HIV drug resistance prevalence was above 5%. This study highlights the potential challenges faced when implementing an ARV-based prevention product that overlaps with first-line antiretroviral therapy. Effective screening to exclude HIV infection among women interested in uptake of ARV-based HIV prevention will be essential in limiting the spread of ARV resistance

Role of the Fractalkine Receptor in CNS Autoimmune Inflammation: New Approach Utilizing a Mouse Model Expressing the Human CX3CR1

Multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system (CNS) is the leading cause of non-traumatic neurological disability in young adults. Immune mediated destruction of myelin and oligodendrocytes is considered the primary pathology of MS, but progressive axonal loss is the major cause of neurological disability. In an effort to understand microglia function during CNS inflammation, our laboratory focuses on the fractalkine/CX3CR1 signaling as a regulator of microglia neurotoxicity in various models of neurodegeneration. Fractalkine (FKN) is a transmembrane chemokine expressed in the CNS by neurons and signals through its unique receptor CX3CR1 present in microglia. During experimental autoimmune encephalomyelitis (EAE), CX3CR1 deficiency confers exacerbated disease defined by severe inflammation and neuronal loss. The CX3CR1 human polymorphism I249/M280 present in ∼20% of the population exhibits reduced adhesion for FKN conferring defective signaling whose role in microglia function and influence on neurons during MS remains unsolved. The aim of this study is to assess the effect of weaker signaling through hCX3CR1I249/M280 during EAE. We hypothesize that dysregulated microglial responses due to impaired CX3CR1 signaling enhance neuronal/axonal damage. We generated an animal model replacing the mouse CX3CR1 locus for the hCX3CR1I249/M280 variant. Upon EAE induction, these mice exhibited exacerbated EAE correlating with severe inflammation and neuronal loss. We also observed that mice with aberrant CX3CR1 signaling are unable to produce FKN and ciliary neurotrophic factor during EAE in contrast to wild type mice. Our results provide validation of defective function of the hCX3CR1I249/M280 variant and the foundation to broaden the understanding of microglia dysfunction during neuroinflammation. © 2018 Cardona et al