Relación de predicción entre la integración social y expectativas académicas en estudantes universitarios de primer año

Las expectativas académicas, la participación del estudiante en las actividades del campus y la facultad, las relaciones con los docentes, compañeros/as, amigos/as y el apoyo familiar tienen un papel fundamental en el ajuste y adaptación al contexto universitario. El objetivo de este estudio es identificar en qué medida la percepción que tienen los estudiantes universitarios de primer año sobre sus relaciones con los docentes, compañeros/as, amigos/as y apoyo familiar recibido predicen sus expectativas académicas transcurrido el primer semestre lectivo. La muestra estuvo formada por 152 estudiantes (50% mujeres) con edades comprendidas entre 18 y 40 años (Mdn=18.5) matriculados en el primer curso de distintas titulaciones del Campus de Ourense. Para medir las expectativas académicas de los estudiantes se utilizó el Cuestionario de Percepciones Académicas (CPA) y para evaluar su equilibrio emocional, la relación con docentes, compañeros/as, amigos/as y familia se usó la Escala de Integración Social en la Educación Superior (EISES-R). Se realizó un análisis de regresión jerárquico por pasos teniendo en cuenta la variable sexo. Los resultados mostraron modelos de predicción significativos diferentes para hombres y mujeres. De acuerdo a ello, los factores de integración social deben ser considerados como un indicador de acciones de intervención para mejorar el ajuste y adaptación de los estudiantes universitarios de primer año a la Educación Superior, siendo necesarias propuestas diferenciadas en función del sexo. Para hombres el foco de actuación debe situarse en la relación con los amigos y la familia, para las mujeres en la relación con los compañeros/as

Avaliação de um protocolo de extração de DNA genômico a partir de sangue total.

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Small Corrections to the Tunneling Phase Time Formulation

After reexamining the above barrier diffusion problem where we notice that the wave packet collision implies the existence of {\em multiple} reflected and transmitted wave packets, we analyze the way of obtaining phase times for tunneling/reflecting particles in a particular colliding configuration where the idea of multiple peak decomposition is recovered. To partially overcome the analytical incongruities which frequently rise up when the stationary phase method is adopted for computing the (tunneling) phase time expressions, we present a theoretical exercise involving a symmetrical collision between two identical wave packets and a unidimensional squared potential barrier where the scattered wave packets can be recomposed by summing the amplitudes of simultaneously reflected and transmitted wave components so that the conditions for applying the stationary phase principle are totally recovered. Lessons concerning the use of the stationary phase method are drawn.Comment: 14 pages, 3 figure

Desempenho de bovinos de corte no pasto suplementados com misturas múltiplas contendo uréia e amiréia.

O presente trabalho foi realizado com o objetivo de avaliar o real potencial da amiréia 1 50S comparada com mistura equivalente em uréia, milho moído e flor de enxofre, como ingredientes em misturas múltiplas para bovinos de corte no pasto; Foram utilizados 40 bezerros sem raça definida, com peso médio de 167 Kg, no período das águas, e 40 bezerros sem raça definida, com peso médio de 285 Kg, no período seco; Os tratamentos foram baseados na amiréia 1 50S e mistura equivalente em milho moído, uréia e flor de enxofre com núcleo mineral e sal, sendo esse em dois níveis para regular consumo

The alpha-galactosidase A p.Arg118Cys variant does not cause a Fabry disease phenotype: data from individual patients and family studies

Acessível em: www.ncbi.nlm.nih.gov/pmc/articles/PMC4423738/Lysosomal α-galactosidase A (α-Gal) is the enzyme deficient in Fabry disease (FD), an X-linked glycosphingolipidosis caused by pathogenic mutations affecting the GLA gene. The early-onset, multi-systemic FD classical phenotype is associated with absent or severe enzyme deficiency, as measured by in vitro assays, but patients with higher levels of residual α-Gal activity may have later-onset, more organ-restricted clinical presentations. A change in the codon 118 of the wild-type α-Gal sequence, replacing basic arginine by a potentially sulfhydryl-binding cysteine residue - GLA p.(Arg118Cys) -, has been recurrently described in large FD screening studies of high-risk patients. Although the Cys118 allele is associated with high residual α-Gal activity in vitro, it has been classified as a pathogenic mutation, mainly on the basis of theoretical arguments about the chemistry of the cysteine residue. However its pathogenicity has never been convincingly demonstrated by pathology criteria. We reviewed the clinical, biochemical and histopathology data obtained from 22 individuals of Portuguese and Spanish ancestry carrying the Cys118 allele, including 3 homozygous females. Cases were identified either on the differential diagnosis of possible FD manifestations and on case-finding studies (n=11; 4 males), or on unbiased cascade screening of probands' close relatives (n=11; 3 males). Overall, those data strongly suggest that the GLA p.(Arg118Cys) variant does not segregate with FD clinical phenotypes in a Mendelian fashion, but might be a modulator of the multifactorial risk of cerebrovascular disease. The Cys118 allelic frequency in healthy Portuguese adults (n=696) has been estimated as 0.001, therefore not qualifying for "rare" condition

Evaluation of HBV-Like circulation in wild and farm animals from Brazil and Uruguay

The origin of the hepatitis B virus is a subject of wide deliberation among researchers. As a result, increasing academic interest has focused on the spread of the virus in different animal species. However, the sources of viral infection for many of these animals are unknown since transmission may occur from animal to animal, human to human, animal to human, and human to animal. The aim of this study was to evaluate hepadnavirus circulation in wild and farm animals (including animals raised under wild or free conditions) from different sites in Brazil and Uruguay using serological and molecular tools. A total of 487 domestic wild and farm animals were screened for hepatitis B virus (HBV) serological markers and tested via quantitative and qualitative polymerase chain reaction (PCR) to detect viral DNA. We report evidence of HBsAg (surface antigen of HBV) and total anti-HBc (HBV core antigen) markers as well as low-copy hepadnavirus DNA among domestic and wild animals. According to our results, which were confirmed by partial genome sequencing, as the proximity between humans and animals increases, the potential for pathogen dispersal also increases. A wider knowledge and understanding of reverse zoonoses should be sought for an effective One Health response

Atividades educativas para portadores de doença crônica: subsídios para a enfermagem

Trata-se de pesquisa de intervenção, realizada em uma Unidade Básica de Saúde do município de Colombo, Paraná, de março a novembro de 2009, com 35 portadores de doença crônica, com idades entre 18 e 60 anos, cadastrados no Programa de Hipertensão e Diabetes. Os objetivos foram: identificar o conhecimento sobre a hipertensão arterial e intervir mediante atividades educativas em grupo. A coleta de dados ocorreu por meio de entrevista semiestruturada e quatro encontros em grupos, e da sua análise emergiram as categorias: “Compreensão da doença” e “Maneiras de cuidar”. Constatou-se que os usuários conhecem a doença, os seus fatores de risco e as possíveis complicações, e que as atividades educativas favoreceram a troca de experiências, proporcionaram a reflexão e a possibilidade de gestão de seu tratamento, e é uma estratégia que deve ser utilizada e divulgada pelos enfermeiros.

ATR-FTIR spectroscopy in blood plasma combined with multivariate analysis to detect HIV infection in pregnant women

Abstract: The primary concern for HIV-infected pregnant women is the vertical transmission that can occur during pregnancy, in the intrauterine period, during labour or even breastfeeding. The risk of vertical transmission can be reduced by early diagnosis. Therefore, it is necessary to develop new methods to detect this virus in a quick and low-cost fashion, as colorimetric assays for HIV detection tend to be laborious and costly. Herein, attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectroscopy combined with multivariate analysis was employed to distinguish HIV-infected patients from healthy uninfected controls in a total of 120 blood plasma samples. The best sensitivity (83%) and specificity (92%) values were obtained using the genetic algorithm with linear discriminant analysis (GA-LDA). These good classification results in addition to the potential for high analytical frequency, the low cost and reagent-free nature of this method demonstrate its potential as an alternative tool for HIV screening during pregnancy