Tectosedimentary and stratigraphic contex in Meirama's coal bassin (A Coruña, Spain).

[Resumen] La sucesión de Unidades Litoestratigráficas dentro de la Cuenca Noeógena de Meirama, demuestra una compleja evolución Tectosedimentaria. Se constata la presencia de médios deposicionales Lacustres, Fluviales, así como grandes periodos de desarrollo forestal. La influencia tectónica dentro de la cuenca, aparece marcada tanto en etapas resedimentárias, como en etapas Sin- y Postsedimentárias.[Abstract] Lithoestratigraphic units succesion in Meirama's Neogene-Bassin, prove a complex Tectosedimentary evolution. It is defined moving of diverse Lacustrine and Fluvial sedimentary environments, also great periods of woodland development. Tectonic influence into bassin, is trade in diverse stages: Pre-, Syn and Postsedimentary ones

Validation and Adaptation of the Prosocial and Antisocial Behavior in Sport Scale to the Spanish context of Physical Education

Physical education (PE), by its own characteristics, is a subject where social communication is especially promoted. However, it is necessary to have tools that evaluate the social behaviour of students during PE classes. For this reason, we propose to validate and adapt the Prosocial and Antisocial Behavior in Sport Scale to the Spanish context of PE classes. The study involved 1081 students aged 12 to 18 (M = 14.83; SD = 1.27). The psychometric properties of the Prosocial Behavior Scale were analyzed through several statistical analyses. The results of the confirmatory factorial analysis and the exploratory factorial analysis supported the internal structure of the questionnaire. In addition, the scale was invariant to gender. Cronbach’s alpha values were higher than 0.70 in the factors and sub-factors, finally showing adequate levels of temporal stability. Taking into account the results achieved in the present study, PE teachers have an effective tool to assess the social and antisocial behaviour of their students’ students during PE classes

Correlación entre dos secuencias lacustres pliocenas en los sectores marginales de Orce y Gorafe (Depresión de Guadix-Baza. Granada)

Las características sedimentológicas (secuencias deposicionales y megasecuencias), estratigráficas (discontinuidades estatigráficas de la misma edad) y estructurales (sistemas de fracturas de salto en di- rección N70E y N135E) permiten deducir un ambiente lacustre-palustre y unas condiciones ambientales-estructurales correlacionables en los dos extremos de la cuenca de Guadix-Baz

Overexpression of mitochondrial if1 prevents metastatic disease of colorectal cancer by enhancing anoikis and tumor infiltration of NK cells

Increasing evidences show that the ATPase Inhibitory Factor 1 (IF1), the physiological inhibitor of the ATP synthase, is overexpressed in a large number of carcinomas contributing to metabolic reprogramming and cancer progression. Herein, we show that in contrast to the findings in other carcinomas, the overexpression of IF1 in a cohort of colorectal carcinomas (CRC) predicts less chances of disease recurrence, IF1 being an independent predictor of survival. Bioinformatic and gene expression analyses of the transcriptome of colon cancer cells with differential expression of IF1 indicate that cells overexpressing IF1 display a less aggressive behavior than IF1 silenced (shIF1) cells. Proteomic and functional in vitro migration and invasion assays confirmed the higher tumorigenic potential of shIF1 cells. Moreover, shIF1 cells have increased in vivo metastatic potential. The higher metastatic potential of shIF1 cells relies on increased cFLIP-mediated resistance to undergo anoikis after cell detachment. Furthermore, tumor spheroids of shIF1 cells have an increased ability to escape from immune surveillance by NK cells. Altogether, the results reveal that the overexpression of IF1 acts as a tumor suppressor in CRC with an important anti-metastatic role, thus supporting IF1 as a potential therapeutic target in CRCThis research was funded by grants from Ministerio de Ciencia, Innovación y Universidades (SAF2013-41945-R, SAF2016-75916-R and SAF2016-75452-R), CIBERER-ISCIII (CB06/07/0017) and Fundación Ramón Areces, Spai

The social engagement of university practice: training the university volunteer in learning communities schools

En la sociedad actual la participación, desde el voluntariado en programas de acción social, es considerada como un valor fortalecedor de las sociedades democráticas, y para el alumnado universitario una oportunidad de complementar su formación profesionalizadora compartiendo experiencias significativas en diversos ámbitos de intervención social. Desde el año 2011, la Facultad de Ciencias de la Educación de la Universidad de Córdoba ha estado colaborando con los centros que han iniciado su transformación en Comunidades de Aprendizaje a través de distintas actuaciones, entre las cuales se sitúa la participación de voluntariado universitario en el proyecto. Esta participación supone un compromiso del alumnado en la puesta en marcha de actuaciones educativas de éxito (AEE) y en la participación en las diferentes comisiones del centro, asistiendo al colegio durante el curso académico y, paralelamente, recibiendo formación sobre las bases científicas de este proyecto. El objetivo de esta comunicación es describir la experiencia de formación del voluntariado universitario en Comunidades de Aprendizaje, realizada a través de dos actividades: Seminario de Iniciación al Voluntariado en Comunidades de Aprendizaje y Seminario de Tertulias Pedagógicas Dialógicas. Estos seminarios pretenden ofrecer al alumnado de grado de las diversas titulaciones de la Facultad de Ciencias de la Educación la oportunidad de participar en experiencias educativas innovadoras que están reconocidas por la Comisión Europea como programas superadores de la exclusión social, como es el caso de las Comunidades de Aprendizaje (INCLUD-ED Consortium, 2006-2011) a la vez que participan durante el curso académico en las prácticas que realizan como voluntarios y voluntarias en las escuelas Comunidades de Aprendizaje de Córdoba. Finalmente, aportamos conclusiones basadas en el análisis de los datos obtenidos en distintos momentos del proceso.In modern societies , participation in volunteer social action is considered as a strengthening factor of democratic societies. For university students is an opportunity to complete their training by sharing meaningful experiences in various areas of social intervention. Since 2011, the Faculty of Education at the University of Cordoba has been working with schools that have begun their transformation into learning communities through various activities , among which a university voluntary participation in the project schools. This participation is a commitment of the students in the implementation of educational strategies for success (ESS) and participation in the various committees of the center, attending school during the academic year and, in parallel, receiving training on the scientific basis of this project. The aim of this paper is to describe the formation of the university experience volunteering in Learning Communities, conducted through two activities: Seminar Introduction to Volunteering Learning Communities and Educational Seminar Tertuliasdialogic . These seminars offered to undergraduate students of various courses at the Faculty of Education the opportunity to participate in innovative educational experiences that are recognized by the European Commission as superseders programs of social exclusion, such as the Communities of Learning (INCLUD-ED Consortium, 2006-2011) while participating in the academic year in practices that perform as volunteers in schools learning Communities Córdoba. Finally, we provide conclusions based on the analysis of data obtained at different monmentsin the process

Evolución de fascies abanico aluvial-fluvial-lacustre en el Plioceno de la Depresión de Guadix-Baza

El corte del Río de Gor muestra la evolución lateral de los materiales de la Fm. Guadix (fluvial) a la Fm. Gorafe-Huelago (lacustre). Desde el borde de la cuenca hacia el interior (en 6 km) se reconocen, en los materiales pliocenos, los siguientes medios sedimentarios yuxtapuestos: A. Abanico aluvial medio. B. Abanico aluvial medio. C. Ríos trenzados (braided). D. Meandriforme proximal. E. Meandriforme distal. F. Llanura lutítica. G. Medio lacustr

Factorizing the time evolution operator

There is a widespread belief in the quantum physical community, and in textbooks used to teach Quantum Mechanics, that it is a difficult task to apply the time evolution operator Exp{-itH/h} on an initial wave function. That is to say, because the hamiltonian operator generally is the sum of two operators, then it is a difficult task to apply the time evolution operator on an initial wave function f(x,0), for it implies to apply terms operators like (a+b)^n. A possible solution of this problem is to factorize the time evolution operator and then apply successively the individual exponential operator on the initial wave function. However, the exponential operator does not directly factorize, i. e. Exp{a+b} is not equal to Exp{a}Exp{b}. In this work we present a useful procedure for factorizing the time evolution operator when the argument of the exponential is a sum of two operators, which obey specific commutation relations. Then, we apply the exponential operator as an evolution operator for the case of elementary unidimensional potentials, like the particle subject to a constant force and the harmonic oscillator. Also, we argue about an apparent paradox concerning the time evolution operator and non-spreading wave packets addressed previously in the literature.Comment: 24 pages; added references; one figure change

Effect of being the organizer of a Handball Worl Championship in team perfomance

Cuando un equipo actúa como local parece tener cierta ventaja. Este hecho se denomina home advantage (HA) y ha sido muy estudiado en competiciones de liga, pero poco en competiciones de sede única. Se analizaron 4.340 partidos disputados en todos los Campeonatos del Mundo de balonmano disputados hasta 2011. Las variables registradas fueron: partidos ganados, empatados, perdidos, número goles marcados y recibidos y sexo de los competidores. La HA en los Campeonatos del Mundo de balonmano es de 67,9±0,23 para la categoría masculina y de 71,2±0,27 para la femenina. Existe una asociación entre la HA, los puntos obtenidos y la clasificación final del equipo.When a team plays at home seems to get some advantage. This effect is called home advantage (HA) and has been widely studied in league competitions, but little in competitions in a single venue. 4.340 games played in all Handballl World Championships since 1936 to 2011 were analyzed. The variables registered were games won, games drawn, games lost, the number of goals scored and goals against and the gender of the competitors. The HA (mean±sd) in the World Handball Championships is 67.9±0.23, for the male category and 71.2±0.27 for the female. A significant association exists between HA, the points obtained in a competition and the final classification of a team

Cannabidiol treatment might promote resilience to cocaine and methamphetamine use disorders: A review of possible mechanisms

Currently, there are no approved pharmacotherapies for addiction to cocaine and other psychostimulant drugs. Several studies have proposed that cannabidiol (CBD) could be a promising treatment for substance use disorders. In the present work, the authors describe the scarce preclinical and human research about the actions of CBD on the effects of stimulant drugs, mainly cocaine and methamphetamine (METH). Additionally, the possible mechanisms underlying the therapeutic potential of CBD on stimulant use disorders are reviewed. CBD has reversed toxicity and seizures induced by cocaine, behavioural sensitization induced by amphetamines, motivation to self-administer cocaine and METH, context- and stress-induced reinstatement of cocaine and priming-induced reinstatement of METH seeking behaviours. CBD also potentiated the extinction of cocaine- and amphetamine-induced conditioned place preference (CPP), impaired the reconsolidation of cocaine CPP and prevented priming-induced reinstatement of METH CPP. Observational studies suggest that CBD may reduce problems related with crack-cocaine addiction, such as withdrawal symptoms, craving, impulsivity and paranoia (Fischer et al., 2015). The potential mechanisms involved in the protective effects of CBD on addiction to psychostimulant drugs include the prevention of drug-induced neuroadaptations (neurotransmitter and intracellular signalling pathways changes), the erasure of aberrant drug-memories, the reversion of cognitive deficits induced by psychostimulant drugs and the alleviation of mental disorders comorbid with psychostimulant abuse. Further, preclinical studies and future clinical trials are necessary to fully evaluate the potential of CBD as an intervention for cocaine and methamphetamine addictive disorders