Elastic growth in thin geometries

International audienceGeneration of shapes in biological tissues is a complex multiscale phenomenon. Biochemical details of cell proliferation, death and mobility can be incorporated within a continuum mechanical framework by specifying locally the amplitude and direction of growth. For tissues exhibiting an elastic behavior, equilibrium shapes of growing bodies can be evaluated through the minimization of an appropriate energy. This model is applied to thin shells and plates, a geometry relevant to nuts and pollen grains but also leaves, petals and algae

On-sky observations with an achromatic hybrid phase knife coronagraph in the visible

CONTEXT: The four-quadrant phase mask stellar coronagraph, introduced by D. Rouan et al., is capable of achieving very high dynamical range imaging and was studied in the context of the direct detection of extra-solar planets. Achromatic four-quadrant phase mask is currently being developed for broadband IR applications. AIMS: We report on laboratory and on-sky tests of a prototype coronagraph in the visible. This prototype, the achromatic hybrid phase knife coronagraph, was derived from the four-quadrant phase mask principle. METHODS: The instrumental setup implementing the coronagraph itself was designed to record the pre- and post-coronagraphic images simultaneously so that an efficient real-time image selection procedure can be performed. We describe the coronagraph and the associated tools that enable robust and repeatable observations. We present an algorithm of image selection that has been tested against the real on-sky data of the binary star HD80081 (* 38 Lyn). RESULTS Although the observing conditions were poor, the efficiency of the proposed method is proven. From this experiment, we derive procedures that can apply to future focal instruments associating adaptive optics and coronagraphy, targeting high dynamic range imaging in astronomy, such as detecting extra-solar planets

Formation et esprit d'entreprendre chez les étudiants

Cette contribution s'attache à étudier entre esprit d'entreprendre et domaine d'études chez les étudiants français. L'esprit d'entreprendre est le substrat dans lequel peut germer l'intention qui pourra donner lieu à une création d'entreprise. Nous choisissons de l'appréhender à partir d'une grille de lecture dérivée du modèle psychosocial du comportement planifié d'Ajzen, enrichie par des variables reflétant l'implication dans la vie associative et les opinions sur les formations à la création d'entreprise.esprit d'entreprendre ; domaine d'étude ; étudiants français

On the variational limits of lattice energies on prestrained elastic bodies

We study the asymptotic behaviour of the discrete elastic energies in presence of the prestrain metric $G$, assigned on the continuum reference configuration $\Omega$. When the mesh size of the discrete lattice in $\Omega$ goes to zero, we obtain the variational bounds on the limiting (in the sense of $\Gamma$-limit) energy. In case of the nearest-neighbour and next-to-nearest-neibghour interactions, we derive a precise asymptotic formula, and compare it with the non-Euclidean model energy relative to $G$

Morphogenesis of growing soft tissues

Recently, much attention has been given to a noteworthy property of some soft tissues: their ability to grow. Many attempts have been made to model this behaviour in biology, chemistry and physics. Using the theory of finite elasticity, Rodriguez has postulated a multiplicative decomposition of the geometric deformation gradient into a growth-induced part and an elastic one needed to ensure compatibility of the body. In order to fully explore the consequences of this hypothesis, the equations describing thin elastic objects under finite growth are derived. Under appropriate scaling assumptions for the growth rates, the proposed model is of the Foppl-von Karman type. As an illustration, the circumferential growth of a free hyperelastic disk is studied.Comment: 4 pages, 3 figure

The smectic order of wrinkles

A thin elastic sheet lying on a soft substrate develops wrinkled patterns when subject to an external forcing or as a result of geometric incompatibility. Thin sheet elasticity and substrate response equip such wrinkles with a global preferred wrinkle spacing length and with resistance to wrinkle curvature. These features are responsible for the liquid crystalline smectic-like behaviour of such systems at intermediate length scales. This insight allows better understanding of the wrinkling patterns seen in such systems, with which we explain pattern breaking into domains, the properties of domain walls and wrinkle undulation. We compare our predictions with numerical simulations and with experimental observations

Time trends in social contacts before and during the COVID-19 pandemic: the CONNECT study

Background Since the beginning of the COVID-19 pandemic, many countries, including Canada, have adopted unprecedented physical distancing measures such as closure of schools and non-essential businesses, and restrictions on gatherings and household visits. We described time trends in social contacts for the pre-pandemic and pandemic periods in Quebec, Canada. Methods CONNECT is a population-based study of social contacts conducted shortly before (2018/2019) and during the COVID-19 pandemic (April 2020 – February 2021), using the same methodology for both periods. We recruited participants by random digit dialing and collected data by self-administered web-based questionnaires. Questionnaires documented socio-demographic characteristics and social contacts for two assigned days. A contact was defined as a two-way conversation at a distance ≤ 2 m or as a physical contact, irrespective of masking. We used weighted generalized linear models with a Poisson distribution and robust variance (taking possible overdispersion into account) to compare the mean number of social contacts over time and by socio-demographic characteristics. Results A total of 1291 and 5516 Quebecers completed the study before and during the pandemic, respectively. Contacts significantly decreased from a mean of 8 contacts/day prior to the pandemic to 3 contacts/day during the spring 2020 lockdown. Contacts remained lower than the pre-COVID period thereafter (lowest = 3 contacts/day during the Christmas 2020/2021 holidays, highest = 5 in September 2020). Contacts at work, during leisure activities/in other locations, and at home with visitors showed the greatest decreases since the beginning of the pandemic. All sociodemographic subgroups showed significant decreases of contacts since the beginning of the pandemic. The mixing matrices illustrated the impact of public health measures (e.g. school closure, gathering restrictions) with fewer contacts between children/teenagers and fewer contacts outside of the three main diagonals of contacts between same-age partners/siblings and between children and their parents. Conclusion Physical distancing measures in Quebec significantly decreased social contacts, which most likely mitigated the spread of COVID-19

Five-factor model personality traits in opioid dependence

<p>Abstract</p> <p>Background</p> <p>Personality traits may form a part of the aetiology of opioid dependence. For instance, opioid dependence may result from self-medication in emotionally unstable individuals, or from experimenting with drugs in sensation seekers. The five factor model (FFM) has obtained a central position in contemporary personality trait theory. The five factors are: Neuroticism, Extraversion, Openness to Experience, Agreeableness and Conscientiousness. Few studies have examined whether there is a distinct personality pattern associated with opioid dependence.</p> <p>Methods</p> <p>We compared FFM personality traits in 65 opioid dependent persons (mean age 27 years, 34% females) in outpatient counselling after a minimum of 5 weeks in buprenorphine replacement therapy, with those in a non-clinical, age- and sex-matched sample selected from a national database. Personality traits were assessed by a Norwegian version of the Revised NEO Personality Inventory (NEO PI-R), a 240-item self-report questionnaire. Cohen's d effect sizes were calculated for the differences in personality trait scores.</p> <p>Results</p> <p>The opioid-dependent sample scored higher on Neuroticism, lower on Extraversion and lower on Conscientiousness (d = -1.7, 1.2 and 1.7, respectively) than the controls. Effects sizes were small for the difference between the groups in Openness to experience scores and Agreeableness scores.</p> <p>Conclusion</p> <p>We found differences of medium and large effect sizes between the opioid dependent group and the matched comparison group, suggesting that the personality traits of people with opioid dependence are in fact different from those of non-clinical peers.</p

Genetic Control of Organ Shape and Tissue Polarity

A combination of experimental analysis and mathematical modelling shows how the genetic control of tissue polarity plays a fundamental role in the development and evolution of form