Bridging University Institutional and Accreditation Standards: An Advanced Practice Registered Nurse (APRN) Program Exemplar

The complexity of the health care environment requires the nursing profession to effectively anticipate current and future health care needs. Similarly, nursing education must ensure preparedness of future nursing professionals as well as meet the rigor of program accreditation standards. South Dakota State University (SDSU) College of Nursing Master’s and Doctor of Nursing Practice (DNP) programs are accredited by the Commission on Collegiate Nursing Education (CCNE), one of the two national specialized accrediting bodies for nursing. Both graduate programs must align with an American Association of Colleges of Nursing (AACN) Essentials document that corresponds to the respective degree and specialty, e.g. family nurse practitioner (FNP). Required curricular framework, components, and competencies are mapped within The Essentials of Master’s Education in Nursing and The Essentials of Doctoral Education for Advanced Nursing Practice. Both documents inform curricular content needed to meet core competencies specific to all Advanced Practice Registered Nursing (APRN) roles, such as the family nurse practitioner (AACN, 2006)

Concentración de inmigrantes y mercado inmobiliario en la ciudad de Barcelona

Diferentes autores mantienen que el sistema de precio de suelo y vivienda existente es un factor que perpetúa la segregación residencial y la desigualdad, situación que se agrava cuando se refiere a algunos grupos de inmigrantes que terminan alojándose en espacios degradados con características por debajo de las mínimas legales de habitabilidad (CORTÉS, 2000; MUSTERD, 2003). Se parte de la hipótesis que la población inmigrante del municipio de Barcelona, se ubica principalmente en esas zonas de menor calidad de vivienda y, que estas zonas de concentración de inmigrantes y menor calidad coinciden con las viviendas de menor precio. Se construyó el Índice de Calidad (iQviv) y el Índice de Características (iCviv) de viviendas. Observando su relación con el Índice de Concentración de Inmigrantes y la evolución del valor de la vivienda 2004-2010 en Barcelona se constató que no siempre las zonas con menor índice de calidad de vivienda y donde se concentran los inmigrantes coincide con las que presentan los precios inmobiliarios más bajos. El mercado inmobiliario es un factor determinante de la estructura socio-espacial de la ciudad, a través del cual se puede modificar el modelo de ciudad que se desea alcanzar respecto a la concentración de colectivos y segregación social. La estrategia residencial gubernamental (localización, régimen de tenencias, diversidad de usos) debe orientar las ciudades hacia la mixtura socio-espacial, la convivencia y el desarrollo social. Y tener mayor incidencia sobre el mercado residencial a fin de evitar una sobrevaloración de la vivienda y especulación de la misma aprovechándose de la necesidad y posibilidades de acceso a la vivienda reducidas de la población más desfavorecida.Different authors have linked the existing land and housing price system as a factor that perpetuates residential segregation and inequality, this situation is exacerbated when it comes to some immigrant groups that end in degraded areas with characteristics below the minimum legal for habitability (CORTÉS, 2000; MUSTERD, 2003). The hypothesis is that immigrant population of Barcelona city is located primarily in those areas of lower quality housing and that this immigrants concentration areas with lower quality housing index matches with the lower housing prices. On this research it was made the Housing Quality Index (iQviv), and the Housing Characteristics Index (iCviv), and it was observed their correlation with the Immigrant Concentration Index (ICI) and the evolution of the Housing Value from 2004-2010, in Barcelona. Observing that the areas with lower housing quality index and where immigrants are concentrated not always matches with the areas that have the lower real estate prices. The housing market is a determinant factor of the social-spatial structure of the city, through which it can be changed the city model to be achieved related with concentration of groups and social segregation. The government residential strategy (in terms of location, tenure arrangements, diversity of uses) should guide the city towards socio-spatial mix, coexistence, and social development of the population. Also it should have a greater impact on the residential market in order to avoid housing speculation and overvaluation, instead of taking advantage of the immigrant population needs, and therefore reducing their possibilities of housing access to.Peer Reviewe

Human papillomavirus type 18 is associated with less apoptosis in fibroblast tumours than human papillomavirus type 16.

In human cervical neoplasia human papillomavirus (HPV) type 18 has a higher cancer/cervical intraepithelial neoplasia (CIN) prevalence ratio than HPV 16. Fibrosarcomas derived from rat fibroblasts transfected with HPV 16 or 18 genomes showed increased apoptosis compared with controls. However, HPV 18 was associated with significantly less apoptosis than HPV 16, affording one possible explanation for the more rapidly progressive cervical neoplasia associated with HPV 18

Increasing the susceptibility of the rat 208F fibroblast cell line to radiation-induced apoptosis does not alter its clonogenic survival dose-response.

Recent studies have suggested a correlation between the rate and incidence of apoptosis and the radiation response of particular cell lines. However, we found that increasing the rate of induction of apoptosis in the fibroblast line 208F, by transfecting it with human c-myc, did not lead to a change in its clonogenic survival dose-response for either gamma-irradiation or 125I-induced DNA damage. It was also found that expression of mutant (T24) Ha-ras in the 208F line appeared to decrease the level of apoptosis per mitosis after irradiation and inhibited the formation of nucleosomal ladders, but did not affect either the onset of the morphological features of apoptosis or the clonogenic survival dose-response of the cells to either gamma-irradiation or 125I-induced DNA damage. Our findings suggest that it may be incorrect to make predictions about the radiosensitivity of cells based only on knowledge of their mode of death

On small proofs of Bell-Kochen-Specker theorem for two, three and four qubits

The Bell-Kochen-Specker theorem (BKS) theorem rules out realistic {\it non-contextual} theories by resorting to impossible assignments of rays among a selected set of maximal orthogonal bases. We investigate the geometrical structure of small $v-l$ BKS-proofs involving $v$ real rays and $l$ $2n$-dimensional bases of $n$-qubits ($1< n < 5$). Specifically, we look at the parity proof 18-9 with two qubits (A. Cabello, 1996), the parity proof 36-11 with three qubits (M. Kernaghan & A. Peres, 1995 \cite{Kernaghan1965}) and a newly discovered non-parity proof 80-21 with four qubits (that improves work of P. K Aravind's group in 2008). The rays in question arise as real eigenstates shared by some maximal commuting sets (bases) of operators in the $n$-qubit Pauli group. One finds characteristic signatures of the distances between the bases, which carry various symmetries in their graphs.Comment: version to appear in European Physical Journal Plu

Phenotype, disease severity and pain are major determinants of quality of life in Fabry disease: results from a large multicenter cohort study.

Quality of life (QoL) is decreased in patients with Fabry disease (FD). To improve QoL, it is important to understand the influence of FD related characteristics, symptoms, and complications. In this retrospective cohort study we explored the effect of pain (measured by the Brief Pain Inventory), phenotype, treatment, and FD-related complications on QoL. QoL data of Fabry patients as assessed by the EuroQol five dimension questionnaire (EQ-5D) from two international centers of excellence were collected. The aim of this study was to evaluate the effect of sex, phenotype, age, different states of disease severity, pain, and ERT on EQ-5D utilities. For 286 adult FD patients (mean age 42.5 years, 40% men, 60% classical phenotype) 2240 EQ-5Ds were available. QoL is decreased in men as well as women with FD, especially in older men with a classical phenotype. At age 50, utility was lower in men with classical FD compared to those with non-classical disease (β = -0.12, 95% CI: -0.23 - 0.01, p = 0.037) with further difference in the years thereafter. Cardiovascular complications, stroke or transient ischemic attacks, multiple FD-related complications and pain were also associated with decreased utilities. Overall, no change in utility was seen in patients on ERT over a mean follow-up of 6.1 years. FD leads to a decreased QoL compared to the general population. Disease complications and pain both negatively influence QoL. Adequate assessment and treatment of pain as well as improved strategies to prevent disease complications are needed to improve QoL in the FD population

Electrobioremediation of oil spills

Annually, thousands of oil spills occur across the globe. As a result, petroleum substances and petrochemical compounds are widespread contaminants causing concern due to their toxicity and recalcitrance. Many remediation strategies have been developed using both physicochemical and biological approaches. Biological strategies are most benign, aiming to enhance microbial metabolic activities by supplying limiting inorganic nutrients, electron acceptors or donors, thus stimulating oxidation or reduction of contaminants. A key issue is controlling the supply of electron donors/acceptors. Bioelectrochemical systems (BES) have emerged, in which an electrical current serves as either electron donor or acceptor for oil spill bioremediation. BES are highly controllable and can possibly also serve as biosensors for real time monitoring of the degradation process. Despite being promising, multiple aspects need to be considered to make BES suitable for field applications including system design, electrode materials, operational parameters, mode of action and radius of influence. The microbiological processes, involved in bioelectrochemical contaminant degradation, are currently not fully understood, particularly in relation to electron transfer mechanisms. Especially in sulfate rich environments, the sulfur cycle appears pivotal during hydrocarbon oxidation. This review provides a comprehensive analysis of the research on bioelectrochemical remediation of oil spills and of the key parameters involved in the process

Photoproduction of pions and etas in nuclei

We calculate the cross sections for inclusive one-pion, two-pion and eta photoproduction in nuclei in the photon energy range from 300 MeV to 900 MeV within the framework of a semi-classical BUU transport model. Our results are compared with existing experimental data and discussed with respect to a calculation of the total photoabsorption cross section.Comment: 30 pages LaTeX including 13 postscript figure

Would you give art to a drowning man?

A symposium to launch the research publication, "PLOT" Organised by Simon Read and Nicky Coutts introduced by Simon Read, artist, senior lecturer in Fine Art with presentations by Maria Thereza Alves, artist,Bergit Arends, curator, Natural History Museum, Dr Jean Fisher, Middlesex University, Fernando Rodriguez Palma, artist, summing up by Dr Martha Fleming. Held at MODA (Museum of Domestic Arhitecture), Middlesex Universit