Transverse size effects in the fragmentation of hadronic strings

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Modulated Phases in Spin-Peierls Systems

Lattice modulations in the high magnetic field phase and close to impurities in spin-Peierls systems are considered and compared to experiment. Necessary extensions of existing theories are proposed. The influence of zero-point fluctuations on magnetic amplitudes is shown.Comment: 10 pages, 4 figures included, to appear in Advances in Solid State Physics/Festkoerperprobleme Spring Conference 1999 of the DP

Spin Excitations in La2CuO4: Consistent Description by Inclusion of Ring-Exchange

We consider the square lattice Heisenberg antiferromagnet with plaquette ring exchange and a finite interlayer coupling leading to a consistent description of the spin-wave excitation spectrum in La2CuO4. The values of the in-plane exchange parameters, including ring-exchange J_{\Box}, are obtained consistently by an accurate fit to the experimentally observed in-plane spin-wave dispersion, while the out-of-plane exchange interaction is found from the temperature dependence of the sublattice magnetization at low temperatures. The fitted exchange interactions J=151.9 meV and J_{\Box}=0.24 J give values for the spin stiffness and the Neel temperature in excellent agreement with the experimental data.Comment: 4 pages, 1 figure, RevTe

Relativistic Hydrodynamics for Heavy--Ion Collisions -- I. General Aspects and Expansion into Vacuum

We present algorithms to solve relativistic hydrodynamics in 3+1--dimensional situations without apparent symmetry to simplify the solution. In simulations of heavy--ion collisions, these numerical schemes have to deal with the physical vacuum and with equations of state with a first order phase transition between hadron matter and a quark--gluon plasma. We investigate their performance for the one--dimensional expansion of baryon-free nuclear matter into the vacuum, which is an analytically solvable test problem that incorporates both the aspect of the vacuum as well as that of a phase transition in the equation of state. The dependence of the lifetime of the mixed phase on the initial energy density is discussed.Comment: 31 pages, 16 uuencoded figure

Hadron and hadron-cluster production in a hydrodynamical model including particle evaporation

We discuss the evolution of the mixed phase at RHIC and SPS within boostinvariant hydrodynamics. In addition to the hydrodynamical expansion, we also consider evaporation of particles off the surface of the fluid. The back-reaction of the evaporation process on the dynamics of the fluid shortens the lifetime of the mixed phase. In our model this lifetime of the mixed phase is <12 fm/c in Au+Au at RHIC and <6.5 fm/c in Pb+Pb at SPS, even in the limit of vanishing transverse expansion velocity. Strangeness separation occurs, especially in events (or at rapidities) with relatively high initial net baryon and strangeness number, enhancing the multiplicity of MEMOs (multiply strange nuclear clusters). If antiquarks and antibaryons reach saturation in the course of the pure QGP or mixed phase, we find that at RHIC the ratio of antideuterons to deuterons may exceed 0.3 and even anti-helium to helium>0.1. Due to fluctuations, at RHIC even negative baryon number at midrapidity is possible in individual events, so that the antibaryon and antibaryon-cluster yields exceed those of the corresponding baryons and clusters.Comment: 17 pages, Latex, epsfig stylefil

Dynamics of Hot Bulk QCD Matter: from the Quark-Gluon Plasma to Hadronic Freeze-Out

We introduce a combined macroscopic/microscopic transport approach employing relativistic hydrodynamics for the early, dense, deconfined stage of the reaction and a microscopic non-equilibrium model for the later hadronic stage where the equilibrium assumptions are not valid anymore. Within this approach we study the dynamics of hot, bulk QCD matter, which is expected to be created in ultra-relativistic heavy ion collisions at the SPS, the RHIC and the LHC. Our approach is capable of self-consistently calculating the freeze-out of the hadronic system, while accounting for the collective flow on the hadronization hypersurface generated by the QGP expansion. In particular, we perform a detailed analysis of the reaction dynamics, hadronic freeze-out, and transverse flow.Comment: 55 pages, 15 figure

Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation

Regulatory T cells (T(reg) cells) are essential for self-tolerance and immune homeostasis. Lack of effector T cell (T(eff) cell) function and gain of suppressive activity by T(reg) cells are dependent on the transcriptional program induced by Foxp3. Here we report that repression of SATB1, a genome organizer that regulates chromatin structure and gene expression, was crucial for the phenotype and function of T(reg) cells. Foxp3, acting as a transcriptional repressor, directly suppressed the SATB1 locus and indirectly suppressed it through the induction of microRNAs that bound the SATB1 3' untranslated region. Release of SATB1 from the control of Foxp3 in T(reg) cells caused loss of suppressive function, establishment of transcriptional T(eff) cell programs and induction of T(eff) cell cytokines. Our data support the proposal that inhibition of SATB1-mediated modulation of global chromatin remodeling is pivotal for maintaining T(reg) cell functionality.Marc Beyer... Timothy Sadlon...Simon C Barry... et al

NK cells and cancer: you can teach innate cells new tricks

Natural killer (NK) cells are the prototype innate lymphoid cells endowed with potent cytolytic function that provide host defence against microbial infection and tumours. Here, we review evidence for the role of NK cells in immune surveillance against cancer and highlight new therapeutic approaches for targeting NK cells in the treatment of cancer