23 research outputs found

    "Invisible burials" and fragmentation practices in Iron Age Europe:Excavations at the Monte Bernorio Necropolis (Northern Spain)

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    The scarcity of burial remains in large parts of Iron Age Europe, particularly in the Atlantic regions, has often led scholars to discuss the apparent “invisibility” of graves. This paper presents the results from several excavation campaigns at Monte Bernorio, one of the most important sites of the 1st millennium b.c. on the Iberian Peninsula. The fieldwork and post-excavation work carried out in the area of the necropolis have identified numerous burial pits, with complex ritual activities characterized by fragmentation and the practice of the pars pro toto. In addition, evidence for later rituals in some of the graves can be linked to ancestor worship. The results provide important insights into funerary practices in Late Iron Age Europe, leading us to rethink the very meaning of cemeteries in the study area and beyond.- Burial Traditions in Iron Age Europe - The Monte Bernorio Archaeological Zone - The 2007–2008 Necropolis Excavations - The 2015–2016 Necropolis Excavations - Post-Excavation Work and Interpretation: The Faunal and Human Remains - Structure and Chronology of Monte Bernorio Area 7 - Destruction of the Body, Commemoration in the Absence of a Corpse, and Visibility of the Mortuary Rite

    : Aristocrates, guerriers et pouvoirs sur les cimes des Alpes-Maritimes

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    International audienceEntre le ve et le iiie siècle avant notre ère, des populations gauloises ont érigé sur un petit sommet du massif du Mercantour une construction monumentale. À l’intérieur des murs, hors du monde ordinaire, aristocrates et élites guerrières y ont tenu d’énigmatiquesbanquets rituels à l’occasion desquels le tissage des liens de hiérarchie et de pouvoir a pu être réaffirmé. Sous les décombres de cet édifice abandonné il y a plus de 2200 ans, archéologues et scientifiques ont retrouvé des sols jonchés d’armes, de bijoux, de restes humains et de reliefs de repas. Au travers de ces vestiges fragmentés, l’histoire de ces lointains ancêtres est revisitée à l’aune de ces nouvelles données qui renversent la perception que nous avions des Gaulois du Mercantour. Au-delà des gestes liés au cérémoniel de ces banquets qui renvoient aux pratiques hellénistiques bien connues, on y découvre une population, nombreuse, hiérarchisée, belliqueuse et intégrée dans un réseau commercial au long cours

    Correction to: Identification of a novel 1,4,8-triazaphenanthrene derivative as a neuroprotectant for dopamine neurons vulnerable in Parkinson's disease

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    Parkinson's disease (PD) is a chronic degenerative disorder characterized by typical motor symptoms caused by the death of dopamine (DA) neurons in the midbrain and ensuing shortage of DA in the striatum, at the level of nerve terminals. No curative treatment is presently available for PD in clinical practice. In our search for neuroprotectants in PD, we generated new 1,4,8-triazaphenanthrenes by combining 6-endo-dig-cycloisomerization of propargylquinoxalines and Suzuki or Sonogashira cross-coupling reactions. Neuroprotection assessment of newly synthesized 1,4,8-triazaphenanthrenes in a PD cellular model resulted in the discovery of a new hit compound PPQ (5m). Neuroprotection by 5m was concentration-dependent and the result of a combined effect on intracellular calcium release channels and astroglial cells. Of interest, 5m also counteracted DA cell loss in a mouse model of PD, making this molecule a promising candidate for PD treatment.Fil: Le Douaron, Gael. Universite Paris Sud; Francia. Universite Pierre et Marie Curie; FranciaFil: Ferrié, Laurent. Universite Paris Sud; FranciaFil: Sepulveda Diaz, Julia E.. Universite Pierre et Marie Curie; FranciaFil: Seon Méniel, Blandine. Universite Paris Sud; FranciaFil: Acuña, Leonardo. Universite Pierre et Marie Curie; Francia. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Raisman Vozari, Rita. Universite Pierre et Marie Curie; FranciaFil: Michel, Patrick P.. Universite Pierre et Marie Curie; FranciaFil: Figadere, Bruno. Universite Paris Sud; Franci
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