Women Faculty of Color, Higher Education, and Sociocultural Change

This capstone will focus on women faculty of color who are underrepresented in faculty positions in predominantly white institutions. Although not all women faculty of color experience discriminatory treatment we can not ignore the lived experiences of these women who are in a disadvantage within academia. The lack of diversification, unequal representation, and socio-cultural understanding prompts society to take a closer insight to determine the necessary steps in facilitating institutional change within higher education. In order to promote equality for women faculty of color I recommend changing the institutionalized policies, developing quality support and mentoring groups in order to hinder negative experiences in job satisfaction that lead to greater retention rates within women faculty of color pursuing tenured or leadership positions

Preparation of [alpha][beta] unsaturated urethanes

Thesis (M.A.)--Boston University, 1948. This item was digitized by the Internet Archive

Impacto de la titulación colectiva en el consejo comunitario de Lloro-Cocoillo Choco Colombia 2012

En este trabajo de investigación, se llevara a cabo un análisis del impacto de la Titulación Colectiva, fundamentada en la ley 70 de 1993, en el Consejo Comunitario Integral de Lloro Cocoillo (Choco Colombia). Se dará a conocer el entorno social, económico, político y cultural de este Consejo Comunitario, forjando un panorama global del desarrollo integral de esta comunidad en busca del reconocimiento del derecho a la propiedad colectiva de las comunidades negras, en donde se deben surtir los trámites de ley que se amplían en el Decreto 1745 de 1995 en su artículo 20, para la Titulación Colectiva de las tierras que habitan.In this research work was carried out an analysis of the impact of collective ownership, based on Law 70 of 1993, the Consejo Comunitario Integral de Lloro Cocoillo (Choco Colombia). A notice of the social, economic, political and cultural development of the Consejo Comunitario, forging a global picture of the development of this community for the recognition of the right to collective ownership of black communities, where paperwork must be filled bill extending the Decree 1745 of 1995, article 20, for the collective titling of the lands they inhabit

Nonconventional Ca(OH) ₂ treatment of bamboo for the reinforcement of cement composites

This study compares the structural and morphological changes in Guadua angustifolia Kunth (GAK) fiber prepared in three different ways (chips, barkless and crushed) when non-conventional alkaline treatment is applied. Moreover, it shows the improvement of mechanical properties of cement composites reinforced with these treated fibers. The three different preparations of Guadua were treated with a saturated solution of calcium hydroxide (5%) at 125 °C and 1.25 kPa for 3 h to remove non-cellulosic compounds. Then, their chemical, morphological, and structural properties were examined. The fibers exhibiting the higher delignification rate were selected to prepare cement composite boards, whose mechanical properties were successively compared with those of composites reinforced with untreated G. angustifolia fibers. The water/cement ratios of the cement mixed with the Ca(OH)2-treated and the untreated fibers were, respectively, around 0.3 and 0.25. The flexural strength and toughness of the two composites were evaluated after 7, 28, and 90 days of curing. The calcium hydroxide treatment showed higher efficiency in removing non-cellulosic materials when performed on crushed bamboo; moreover, the mechanical properties of the composites reinforced with the treated fibers were higher than those mixed with the untreated ones. After 90 days of curing, the flexural strength increased by around 40% and the toughness became three times higher (p < 0.05). The mechanical improvement by the Ca(OH)2 treatment of G. angustifolia fibers demonstrates its potential for the fabrication of cement composites

The ASO Nusinersen ameliorates motor function and prevents Cajal body disassembly and abnormal poly(A) RNA distribution in motor neurons from a Spinal Muscular Atrophy mouse model

ABSTRACT : Spinal muscular atrophy (SMA) is a devastating autosomal recessive neuromuscular disease characterized by degeneration of spinal cord alpha motor neurons (αMNs). It is caused by the homozygous deletion or mutation of the survival motor neuron 1 (SMN1) gene, resulting in reduced expression of SMN protein, which leads to αMN degeneration and muscle atrophy. A second gene, SMN2, contains a mutation that promotes exclusion of exon 7 and causes the SMN2 transcripts to generate a truncated, nonfunctional, form of SMN: the SMN∆7 protein. A recent treatment with antisense oligonucleotides (ASOs) has been developed for SMA – Nusinersen (Spinraza, BIOGEN), which works by promoting the inclusion of exon 7 in SMN2 transcripts. In this work, we used the αMNs of the SMN∆7 mouse model of SMA to study the effects of Nusinersen in the behavior of Cajal bodies (CBs) and the cellular distribution of polyadenylated mRNAs. CBs are nuclear structures involved in RNA metabolism that can be disrupted in response to cellular stress in SMA αMNs. Moreover, an abnormal accumulation of polyadenylated mRNAs in nuclear granules (PARGs) have been previously shown in αMNs from the SMN∆7 mouse model of SMA. Notably, in our study we demonstrate that the treatment with Nusinersen, administered via intracerebroventricular injection, rescues growth curve and improves motor behavior in these mice. Importantly, Nusinersen also recovers the number of canonical CBs and reduces the abnormal accumulation of polyadenylated RNAs in nuclear granules or PARGs. Furthermore, the treatment with this ASO normalizes the expression of the pre-mRNAs encoding chondrolectin and choline acetyltransferase, two key factors for αMNs homeostasis. In light of these results, we propose that the mechanism of action of Nusinersen is partially mediated by the rescue of both CB biogenesis and the normal processing and distribution of polyadenylated mRNAs. It also becomes apparent that the rescue of SMN levels in the spinal cord has a beneficial effect on αMNs and skeletal myofibers, but the rescue of SMN expression in muscle is needed for the complete recovery of motor function.Máster en Biología Molecular y Biomedicin

La relación pedagógica estudiante-enfermera: un estudio hermenéutico-fenomenológico

Objetivo: esta investigación estudió el significado de la relación pedagógico en la formación del estudio de enfermería y caracteriza el papel que esta relación posee en la práctica del cuidado, reflexiva, relacional y ética del estudiante. Método: investigación cualitativa con abordaje hermenéutico fenomenológico de Gadamer, etnográfico. Desarrollado durante la pasantía clínica de 11 alumnos con su respectivo profesor e instructor clínico de una Escuela de Enfermería en Barcelona, entre febrero de 2011 y febrero de 2012. Las estrategias de recolección de datos fueron: observación participante, conversas informales, entrevistas a profundidad y materiales escritos. Para su análisis fue utilizado el método comparativo constante de Glasser y Strauss. Resultados: la relación pedagógica orientada para el alumno emergió como el núcleo temático que incluyó categorías tales como "estar para el alumno", "confianza" y "autonomía". Conclusión: la relación pedagógica orientada para el alumno es una relación de cuidado que ofrece acompañamiento, confianza, presencia, empoderamiento y autonomía

Cuidados de Enfermagem à Gestante Com Diabetes Gestacional

Este estudo é realizado no âmbito do Trabalho de Conclusão de Curso de Licenciatura em Enfermagem, na Universidade do Mindelo e trata da sistematização da assistência de enfermagem prestada à gestante com diabetes gestacional durante o pré natal, através de consulta de enfermagem e das acções educativas realizadas às gestantes. Escolhemos trabalhar este tema, primeiramente por motivos pessoais, uma vez que ambas trabalhamos no serviço de Ginecologia-Obstetrícia do Hospital Baptista de Sousa e, em segundo lugar, porque queremos dar resposta sobre a forma como os enfermeiros prestam cuidados às gestantes com diabetes gestacional. Para o desenvolvimento do presente trabalho, utilizámos o método de revisão de literatura, como metodologia base e também realizámos entrevistas semi-estruturadas e observação participante.A gestação é um processo natural que envolve múltiplas mudanças, a vários níveis, tanto fisiológicos, como psico-sociais e emocionais. Dentro das mudanças fisiológicas, pode surgir a diabetes gestacional. Assim, considerando que a intervenção de enfermagem pré-natal e atendimento hospitalar eficiente podem diminuir expressivamente a morbilidade e mortalidade materna e fetal, tendo como causa a diabetes gestacional. Concluímos que o aprimoramento técnico e científico do enfermeiro, muito pode contribuir no acompanhamento destas gestantes dentro de uma equipa multidisciplinar e, consequentemente, alcançar o equilíbrio e o bem-estar, tanto materno como fetal, nos procedimentos, diagnóstico e tratamento da diabetes gestacional

Efectividad del tratamiento inmunomodulador con leucocitos alogénicos, en aborto involuntario recurrente. Revisión sistemática y metaanálisis

Dentro del marco del aborto involuntario recurrente (AIR), se han propuesto causas autoinmunes y alogénicas, e implementación de terapias como la inmunización activa con leucocitos alogénicos de la pareja o de donantes. La evidencia disponible en cuanto a la efectividad de estos tratamientos es contradictoria, por lo que se desea realizar una revisión sistemática para evaluar la efectividad de la inmunización activa con leucocitos alogénicos de la pareja o de donantes para esta condición. Se realizó un estudio tipo revisión sistemática de la literatura, usando las siguientes bases de datos: Medline, Embase, Cochrane Library y Scielo. Se realizó una búsqueda a través del registro de ensayos clínicos del Instituto Nacional de Salud de los Estados Unidos (www.clinicaltrials.gov) y, una búsqueda manual a través de las referencias de los estudios seleccionados siguiendo la estrategia de bola de nieve. Se seleccionaron ensayos clínicos y estudios de cohorte analítica, en idioma inglés y español. Se realizó un análisis cuantitativo de la información por medio de un metaanálisis. El tratamiento inmunomodulador con linfocitos puede considerarse como una terapia efectiva para mantener la gestación y lograr recién nacido vivo según resultados estadísticos; sin embargo la calidad de los estudios incluidos es baja, por lo que no se aconseja para la práctica rutinaria. Se sugiere la realización de estudios con metodologías robustas y que apoyen los resultados presentados en esta investigación.Involuntary recurrent abortion (IRA) is defined as the history of three or more abortions before 20 weeks of gestation. Within its etiology has been proposed and allogeneic or autoimmune causes, with the implementation of therapies that try to immunize women against "foreign" cells of a future pregnancy like the trophoblast membrane immunization, active immunization with allogeneic leukocytes partner or donor and the use of intravenous immunoglobulin (IVIG). The available evidence regarding their effectiveness is scarce and contradictory, which is why we want to conduct a systematic review to assess the effectiveness of this treatment, measured by the rate of live births in women with AIR, who were treted by immunomodulator, and the adverse events presented in the mother and child. Asystematic review of the literature will be conducted. First, a search will be make through the following databases: Medline, Embase, Cochrane Library and Scielo. Also a search made through the registration of clinical trials at the National Institute of Health in the United States (www.clinicaltrials. gov) and finally manual search will be made through the references of the selected studies following the snowball strategy. The following search terms will be used: Human, pregnancy, involuntary recurrent abortion, prevention, control, immunotherapy, immunization, allogeneic leukocytes, trophoblast, newborn, controlled clinical trials, cohort, in different combinations. If the studies allow a quantitative analysis of the information will be made. This systematic review will provide evidence about the effectiveness of immunomodulatory treatments to achieve pregnancy and live birth and assess gestational week at birth and complications in the newborn. The results will serve to discuss the use of inmunomodulator treatment in cases of IRA. It will serve as a starting point for the implementation of a treatment strategy that is beneficial to patients and complement existing clinical practice protocols

El cine - foro como estrategia didáctica para la educación en competencias comunicativas y afectivas para la ciudadanía

El cine ha sido utilizado como una estrategia comunicativa efectiva en diversos contextos, ya que permite reflejar en un ambiente realista las características de una situación específica. El presente estudio es de orden cualitativo con enfoque descriptivo y utiliza el cine-foro como estrategia didáctica para la educación en competencias comunicativas y afectivas para la ciudadanía. El estudio se realizó con 73 estudiantes de la asignatura Filosofía e Historia de los Valores de la Vida, del Programa Ciencias del Deporte y la Recreación, de la Facultad de Ciencias de la Salud, de la Universidad Tecnológica de Pereira, durante el año 2012. Esta asignatura fundamenta sus contenidos en el conocimiento de la ética, la moral, los valores y los referentes teóricos y filosóficos que los sustentan. Busca que los estudiantes adquieran competencias para expresarse con autonomía e identifiquen tipos de valores, tradiciones y creencias de otros grupos culturales y sociales. Se eligieron 11 películas del género drama, las cuales fueron distribuidas aleatoriamente a los estudiantes en subgrupos de 3 personas. Las películas fueron vistas por cada subgrupo y presentadas al grupo completo de una forma creativa, utilizando actividades, herramientas y métodos elegidos por ellos, con el propósito de dar a entender a sus compañeros la esencia de las mismas, en la cual propiciaban el acercamiento con la realidad con una intencionalidad definida. Este proceso llevó a comprender algunos aspectos sociales, culturales, políticos, religiosos y económicos de diferentes culturas y apropiarse de herramientas conceptuales que incitaron a la reflexión de forma clara y participativa.Cinema has been used as an effective communicative strategy in a number of teaching situations, since it allows to reflect, in a realistic environment, the characteristics of a specific situation. The present study is qualitative with a descriptive focus and employs the film forum as a didactic strategy for education in communicative and affective competencies for citizenship. This study was performed with 73 students of the Philosophy and History of Life Values subject, from the Faculty of Health Sciences in the Universidad Tecnológica de Pereira, during 2012. The content of this subject is based on the knowledge of ethics, morality and human values and the theoretic basis of these concepts. This subject pretends that students achieve competencies to express themselves with autonomy and to identify different types of human values, traditions and beliefs from other cultural and social backgrounds. 11 drama films were chosen, which were assigned to 3-student groups. The films were watched by each group and then they were presented to the whole group in a creative way employing different activities, tools and methods with the goal of giving to all the students elements to understand the essence of the film and facilitate an approach to reality with a definite intentionality. This process allows to understand some social, cultural, politic, religious and economic aspects from different cultures and to grab conceptual tools toward reflection in a clear and participative way