Calcificaciones heterotópicas en cirugía protésica de cadera: Prótesis bicénctricas vs híbridas

Realizamos el seguimiento clínico y radiológico de 202 pacientes a los que se implantó una Prótesis Total de Cadera cementada (PTC). Analizamos la presencia de calcificaciones heterotópicas (CH) y su graduación, estudiando separadamente prótesis híbridas y bicéntricas. Valoramos los factores de riesgo relacionados con la aparición de CH, tamaño de implantes, alineación final, lado intervenido y relación con la presencia de complicaciones locales y sistemáticas. La prevalencia de CH fue de 35.5% (grado I, 19%; grado II, 10%; grado III, 5% y grado IV 1,5%); 9,9 % sintomáticas. Una mayor proporción de CH fue observada en varones (p=0,005); vástagos de mayor tamaño (p=0,001). No existen diferencias significativas (p=0,059) entre pacientes con prótesis híbridas frente a aquellos con prótesis bicéntricas. La valoración de Harris mostró diferencias en el seguimiento del parámetro dolor a los 24 meses entre los grupos con y sin CH.The clinical and radiological follow-up of 202 patients with a cemented Hip Artrhoplasty (HA) was reviewed. The presence of periarticular heterotopic ossifications (PHO) and its gradation was compared i9n hybrid and bipolar arthroplasties. Risk factors related to the appearance of PHO, implants size, final alignment, operated side and relationship to the postoperative local and systemic complications were several of the parameter analyzed. The presence of PHO was 35,5% (degree I, 19%; degree II, 10%; degree III, 5% and degree IV, 1,5%); 9,9% symptomatic. A greater proportion of PHO was observed in males (p=0,005) greater zie stems (p=0,001) and patients with postoperative local complications (p=0,001). There were no statistical differences between patients with hybrid hip arthoplasties as compared to those with bipolar his arthroplasties. The Harris score showed differences as regards pain at 24 months follow-up between the groups whit an without PHO

Electronic Descriptors for Supervised Spectroscopic Predictions

Spectroscopic properties of molecules holds great importance for the description of the molecular response under the effect of an UV/Vis electromagnetic radiation. Computationally expensive ab initio (e.g. MultiConfigurational SCF, Coupled Cluster) or TDDFT methods are commonly used by the quantum chemistry community to compute these properties. In this work, we propose a (supervised) Machine Learning approach to model the absorption spectra of organic molecules. Several supervised ML methods have been tested such as Kernel Ridge Regression (KRR), Multiperceptron Neural Networs (MLP) and Convolutional Neural Networks. The use of only geometrical descriptors (e.g. Coulomb Matrix) proved to be insufficient for an accurate training. Inspired on the TDDFT theory, we propose to use a set of electronic descriptors obtained from low-cost DFT methods: orbital energy differences, transition dipole moment between occupied and unoccupied Kohn-Sham orbitals and charge-transfer character of mono-excitations. We demonstrate that with this electronic descriptors and the use of Neural Networks we can predict not only a density of excited states, but also getting very good estimation of the absorption spectrum and charge-transfer character of the electronic excited states, reaching results close to the chemical accuracy (~2 kcal/mol or ~0.1eV)

Estudio de tres técnicas de concentración de proteína para la determinación del perfil proteico en Condensado de Aire Exhalado

Comunicaciones a congreso

Vástago femoral PMC en cirugía protésica de cadera: revisión clínica y radiológica

Evaluamos los resultados clínicos y radiológicos de nuestros 100 primeros casos consecutivos de sustitución protésica de cadera mediante modelo de vástago cementado PMC, realizando un seguimiento mínimo de 30 meses. La media de edad de los pacientes intervenidos ha sido de 75 años. El diagnóstico en 31 de los casos fue de coxartrosis, 63 fracturas y 6 otros. El 94% de los pacientes fueron intervenidos por abordaje posterolateral. La puntuación según la escala de Harris modificada fue de 82 puntos, 92 para las prótesis híbridas y 72 para las bicéntricas. Los hallazgos clinicorradiológicos sólo mostraron el aflojamiento de 1 vastago en la serie; no encontramos alteraciones en la interfaz cemento-prótesis.We reviewed 100 consecutive hip arthroplasties with a cemented femoral component (PMC) after 30 months of follow-up. The average age of patients was 75 years. The diagnosis was osteoarthritis in 31 hips, fractures in 63 hips and others in 6. 94% hip arthroplasties were performed through the posterolateral approach. The mean Harris score at latest 30-month follow- up, was 82 points, 92 points in hybrid arthroplasties and 72 in bipolar arthroplasties. Radiographic and clinic follow-up had showed loosening of 1 stem, without abnormalities in the interface cement-prosthesis

Clinical and Immunopathologic Profile of Mexican Patients with IgG4 Autoimmune Pancreatitis

Autoimmune pancreatitis is part of the spectrum of IgG4-associated diseases. Its diagnostic criteria and histological subtypes have been formally proposed recently and although based on current data it has been suggested that there are differences in clinical presentation among populations, more research is needed to properly establish if this heterogeneity exists. In this paper, we describe 15 cases of autoimmune pancreatitis diagnosed at a Mexican centre of reference, all of them associated to the lymphoplasmocytic sclerosing pancreatitis variant. The mean age at the onset of symptoms was 47.5 ± 14.4 years, and 53% of patients were male. The main manifestations were weight loss (87%), obstructive jaundice (53%), and acute (27%) and chronic (27%) pancreatitis. Only 20% of patients had high IgG4 serum levels at the time of diagnosis. All patients receiving prednisone responded favourably, both in their pancreatic and extrapancreatic manifestations. Clinical manifestations of Mexican patients showed certain differences with respect to those usually reported

Pensar el Estado y la sociedad : desafíos actuales

Las reflexiones contenidas en esta coedición deben contribuir a restablecer la imprescindible relación entre conocimientos y experiencias, entre teoría y práctica, que demandan los procesos emancipatorios nacionales y latinoamericanos en la transición que vivimos. Ésta como dice Boaventura deberá moverse en el experimentalismo propio que demandan circunstancias de incertidumbre y de ausencia de recetas de futuro, pero cuyo carácter debería ser la multiplicación de formas de deliberación democrática como garantía para remontar el riesgo de su fractura y revisión.Presentación 7 1. Reinventando la emancipación social 13 2. Debate sobre la universidad del siglo XXI 37 3. Los desafíos de las ciencias sociales hoy 101 4. ¿Estamos condenados a ser gobernados? 121 Conversatorio sobre universidad popular para los movimientos sociales 5. La reinvencion del Estado y el Estado plurinacional 13

Morphological and ultrasonographic characterization of the three zones of supratesticular region of testicular artery in Assaf rams

[EN] To fully understand the histological, morphometrical and heamodynamic variations of different supratesticular artery regions, 20 mature and healthy Assaf rams were examined through ultrasound and morphological studies. The testicular artery images of the spermatic cord as shown by B-mode analysis indicated a tortuous pattern along its course toward the testis, although it tends to be less tortuous close to the inguinal ring. Doppler velocimetric values showed a progressive decline in flow velocity, in addition to pulsatility and vessel resistivity when entering the testis, where there were significant differences in the Doppler indices and velocities among the different regions. The peak systolic velocity, pulsatility index and resistive index were higher in the proximal supratesticular artery region, followed by middle and distal ones, while the end diastolic velocity was higher in the distal supratesticular region. The total arterial blood flow and total arterial blood flow rate reported a progressive and significant increase along the testicular cord until entering the testis. Histological examination revealed presence of vasa vasorum in the tunica adventitia, with their diameter is higher in the proximal supratesticular zone than middle and distal ones. Morphometrically, the thickness of the supratesticular artery wall showed a significant decline downward toward the testis; meanwhile, the outer arterial diameter and inner luminal diameter displayed a significant increase distally. The expression of alpha smooth muscle actin and vimentin was higher in the tunica media of the proximal supratesticular artery zone than in middle and distal ones.SIThe authors acknowledge the staff members and technicians of Comparative Anatomy and Pathology Department, and Animal Medicine and Surgery Department, Faculty of Veterinary Medicine, León University, Spain, and specially Professor P de Paz for their great help in the practical and laboratory parts of this study. Many thanks are extended to staff member of Anatomy and Embryology Department, Faculty of Veterinary Medicine, Sohag University, for their help with histological and morphometrical analyses. We are thankful and grateful for European Union for the financial support of this study through the project (ERASMUS+ KA107 2019/2020). This work was financially supported by the Junta de Castilla y León (LE253P18) and MINECO (AGL2017-83098-R) project and the University of León, and also by Sohag University, Egypt.This article was funded by Ministerio de Economía, Industria y Competitividad, Gobierno de España (AGL2017-83098-R) and Junta de Castilla y León (LE253P18)

Efecto del campo el?ctrico en la estructura cristalina de cer?micas submicroestructuradas DE (1-X)(Bi0.5Na0.5)TiO3- X BaTiO3 con composici?n pr?xima a la frontera morfotr?pica

--El sistema (1-x)(Bi0.5Na0.5)TiO3 - x BaTiO3 (BNBT100x) presenta una frontera morfotr?pica [1] (MPB) por lo que se presenta como posible material piezoel?ctrico "lead-free". Muy recientemente se han puesto de manifiesto peculiaridades estructurales de este sistema cerca de la MPB. La naturaleza y el rol de ordenamientos at?micos locales diferentes del orden global y la posibilidad de simetr?as inferiores a la rombo?drica son temas de actualidad. Exploramos aqu? el gran potencial de la difracci?n en alta resoluci?n de radiaci?n sincrotr?nica y el ajuste por Rietveld de los difractogramas de alta resoluci?n completos [2], que permite una mejor caracterizaci?n de las fases presentes que en los habituales an?lisis de grupos de picos aislados. Se determina el efecto del campo el?ctrico aplicado en cer?micas submicro- estructuradas [3] de composiciones BNBT4 y BNBT6 obtenidas a partir de precursores nanom?tricos preparados mediante autocombusti?n de sol-gel. Los experimentos de difracci?n se desarrollaron en el sincrotr?n de Stanford (USA) con radiaci?n de 12 keV. Para todas las muestras analizadas se consider? el difractograma completo para un recorrido del vector de dispersi?n Q entre 0 y 6.4?-1. En todos los casos investigados, se esclareci? la ocurrencia de las fases tetragonal P4mm, rombo?drica R3c y/o monocl?nica Cc. Se dan resultados cuantitativos de ocurrencia, concentraciones relativas, forma y tama?o de part?culas y orientaciones preferente