Straightforward synthesis of enantiomerically pure 1, 2, 3-triazoles derived from amino esters

A practical and straightforward approach that enables for the first time, the synthesis of enantiomerically pure 1,4,5-trisubstituted, 1,5-disubstituted, and fused 1,2,3 triazole derivatives has been developed. The synthesis employs enantiomerically pure amino esters derived from amino acids and commercially available ketones under metal-free conditions.status: publishe