Validación del Inventario de Supresión del Oso Blanco en Población Mexicana

Thought suppression is the general tendency to suppress unwanted, negative thoughts and the inability to ignore unwanted intrusive thoughts. The purpose of this study was to develop a translated version of the White Bear Suppression Inventory (WBSI) that is reliable and valid in a Mexican sample. A back-to-back translation of the WBSI was made, and the WBSI- Mexican Version (WBSI-MV) was administered to a sample of 346 undergraduate students enrolled at university in northern Mexico. Support was found for a two-factor solution, with factors labeled intrusion and suppression, which is consistent with previous research. Furthermore, support was found for the validity of the WBSI-MV, as both subscales were considered to be significantly and positively associated with measures of obsessive-compulsive disorder symptoms and thought-action fusion. Overall, the WBSI-MV proved to be a valid measure that can be used to assess suppressive and intrusive thoughts in the Mexican population.El Inventario de Supresión del Oso Blanco (WBSI) se encuentra entre los instrumentos de autoinforme más utilizados para evaluar la supresión del pensamiento, la tendencia general a suprimir los pensamientos negativos no deseados y la incapacidad de ignorarlos. El propósito del presente estudio fue desarrollar una versión traducida del WBSI que sea confiable y válida en una muestra mexicana. Se realizó una traducción y se administró a 346 estudiantes universitarios en el norte de México. Los resultados mostraron una solución de dos factores, etiquetados como intrusión y supresión, lo cual es consistente con investigaciones previas. Además, se apoyó la validez de la versión mexicana (WBSI-MV), ya que ambas subescalas estaban asociadas de manera significativa y positiva con medidas de síntomas de trastorno obsesivo compulsivo y fusión de pensamiento-acción. En general, se mostró que el WBSI-MV es un instrumento válido que puede utilizarse para evaluar los pensamientos supresivos e intrusivos en la poblaciónmexicana

Molecular detection and parasite load of Trypanosoma cruzi in digestive tract tissue of Chagas disease patients affected by megacolon

Chagas disease, caused by the Trypanosoma cruzi parasite in the Americas affects similar to 7 million people, 30% with cardiac tissue damage and 10-15% with digestive disorders. In this study, we have developed a protocol to detect the presence of the parasite and estimate its load in resected dysfunctional tissue segments of chronically infected patients with digestive megacolon. We have included samples from 43 individuals, 38/5 with positive/negative serology for Chagas disease and digestive syndromes. Samples of 1.5 to 2.0 cm(2) were taken from different points of the dysfunctional digestive tract in specialized centres in Cochabamba, Bolivia. T. cruzi cultures were performed by inoculation with NNN-LIT culture medium, and genomic material was obtained from the samples for multiplex qPCR with TaqMan probes targeting satellite nuclear DNA. Cultures failed to isolate T. cruzi but qPCR reached a sensitivity of 42.1% (16/38) with all three spots and in triplicate. A new quantification methodology using synthetic satellite DNA as quantitation standard revealed parasite loads ranging from 2.2 x 10(2) to 1.0 x 10(6) satellite DNA copies/mu l. Positive samples from the distal end showed a higher parasite load. The results of the present study strengthen and add further evidence to previous findings in an experimental mouse model of chronic T. cruzi infection, providing a valuable tool to improve scientific knowledge on the relevance of the digestive tract in parasite persistence, and underline the need of a better understanding of host-pathogen interaction in digestive tissues, considering pathophysiology, disease immunology and response to treatment

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

“ASOCIACIÓN DEL CONTROL GLUCÉMICO Y EL TIEMPO DE EVOLUCIÓN DE LA DIABETES MELLITUS CON LA FUNCIÓN SEXUAL EN LAS MUJERES DE 20 A 49 AÑOS DE EDAD ADSCRITAS A LA UNIDAD DE MEDICINA FAMILIAR NO. 64 DE TEQUESQUINAHUAC”

Resumen .- Antecedentes: En la literatura internacional se describen cambios en la función sexual femenina con respecto a los cambios climatéricos, sin embargo son pocos los estudios que realizan una asociación entre la presencia de diabetes mellitus con un cambio en la función sexual de la mujer en contraste con la abundante investigación en diabetes mellitus y función sexual masculina. Objetivo: Asociar el control glucémico y el tiempo de evolución de la diabetes mellitus con la función sexual en las mujeres de 20 a 49 años de edad adscritas a la Unidad de Medicina Familiar Número 64. Material y métodos: Se realizó un estudio de tipo observacional, prospectivo, transversal, analítico. La muestra constituida de 280 mujeres diabéticas de 20 a 49 años de edad, previo consentimiento informado se otorgó el instrumento de auto aplicación: Escala de experiencia sexual de Arizona ASEX. Análisis de datos: Para realizar estadística descriptiva se utilizó el programa estadístico SPSS 23, para calcular medidas de tendencia central a las variables cuantitativas, así como frecuencias y porcentajes para variables cualitativas, para el análisis bivariado de se calcularon X2 y V de Crammer. Resultados: Se encontró que la función sexual de las 280 participantes, el 44.3% de la muestra se clasifica con función sexual normal, mientras que 55.7% presentó disfunción sexual; En la asociación entre el control glucémico con la función sexual, se encontró que el 66% de las participantes con control glucémico adecuado presentó función sexual normal, mientras que el 34 % de ellas presento disfunción sexual. Con respecto a las pacientes con descontrol glucémico se obtuvo que 34.4% presentó función sexual normal, y el 65.6 % que presentó disfunción sexual se calculó X2 con una p= 0.000 y V de Cramer 0.295 con p=0.000; para la asociación entre el tiempo de evolución de la diabetes mellitus con la función sexual, se reporta que el 32% de las participantes con un tiempo de evolución de la enfermedad igual o mayor a 10 años presentó función sexual normal, mientras que el 68 % de ellas presento disfunción sexual. Con respecto a las pacientes con menos de 10 años de evolución de la diabetes mellitus se obtuvo que 48.7% presentó función sexual normal, y el 51.3 % que presentó disfunción sexual, calculando X2 con una p= 0.012 y V de Cramer 0.150 con p=0.000 Conclusiones: La función sexual de las mujeres diabéticas de 20 a 49 años de edad, presenta asociación con correlación significativa con el control glucémico, así como con el tiempo de evolución de la enfermedad. PALABRAS CLAVE: Función sexual, control glucémico y tiempo de evolución de la diabetes mellitus

Methodologies for Monitoring the Digital Marketing of Foods and Beverages Aimed at Infants, Children, and Adolescents (ICA): A Scoping Review

While television has been the most widely used medium for food and beverage marketing, companies are shifting in favor of digital media. The ubiquitous digital marketing of breast-milk substitutes (BMS) and foods and beverages high in saturated fat, salt, and/or free sugars (FBHFSS) has been considered a powerful environmental determinant of inadequate dietary practices during infancy, childhood, and adolescence. The scoping review’s aim was to systematically identify and map the types of methodologies available to monitor the digital marketing of foods and beverages targeting infants, children, and adolescents (ICA) worldwide. Research evidence published from 2011 to October 2021 was examined using search strategies including multiple databases and citation tracking. A total of 420 sources were evaluated, and 28 studies from 81 countries meeting the inclusion criteria were retained. Most of the studies (n = 24) documenting methodologies to monitor inappropriate digital marketing were published since 2015 and were primarily aimed at identifying the promotional techniques and nutritional content of FBHFSS targeting adolescents (n = 13). It is paramount to develop a feasible and scalable monitoring system to develop effective policies to protect parents and ICA from BMS and FBHSFF digital marketing