966 research outputs found

    Tabaquismo en la consulta de enfermería de atención primaria

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    La Sociedad Científica Española de Enfermería –SCELE, ha realizado en la Facultad de Ciencias de la Salud de la Universidad de Alicante, los días 9 y 10 de Junio de 2016, el VIII Congreso Nacional SCELE, bajo el lema: "LIDERAZGO DE ENFERMERÍA EN LA GESTIÓN DE CUIDADOS EN LA CRONICIDAD". Se ofrece el acceso a los Resúmenes de las Comunicaciones Científicas Orales y Posters presentadas y defendidas en el trascurso del mencionado Congreso, en sus distintas categorías: estudios de investigación, proyectos de investigación y casos de cuidados

    Evaluación de la actividad antifúngica de nanoparticulas de Zno obtenidas del reciclado de pilas alcalinas agotadas

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    El objetivo de este trabajo es analizar las propiedades estructurales, ópticas y antifúngicas de dos ZnO obtenidos de pilas alcalinas agotadas, dado que el ZnO es ampliamente utilizado debido a sus propiedades ópticas y electrónicas, las cuales dependen del método de síntesis, y las formas y tamaños de las nanopartículas preparadas

    Sociomoral Reasoning in Children and Adolescents from Two Collectivist Cultures

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    This study compared the sociomoral reasoning of 7-, 9-, 12-, and 15-year-old children and adolescents of two collectivistic cultures in the 1990s: Spain (horizontal collectivism; N = 208) and Russia (vertical collectivism; N = 247). Participants reasoned about choices and moral justifications of a protagonist in a sociomoral dilemma where participants can focus on different moral and non-moral concerns (e.g., going with their best friend, going with a new classmate or trying to do something with both). Results support previous research in western societies: Participants tend to choose the option “visiting the best friend”, and self-interest tends to decrease with age whereas altruism tends to increase. Moreover, Spanish participants tended to consider all parties involved in the dilemma (i.e., old friend and new classmate), whereas Russian participants did not. These results are discussed in light of their differences as horizontal and vertical collectivistic societies. Overall, the results open an avenue for new studies when comparing the effects of culture on children’s and adolescents’ development

    Sex differences in mortality in patients with COPD

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    Little is known about survival and clinical prognostic factors in females with chronic obstructive pulmonary disease (COPD). The aim of the present study was to determine the survival difference between males and females with COPD and to compare the value of the different prognostic factors for the disease. In total, 265 females and 272 males with COPD matched at baseline by BODE (body mass index, airflow obstruction, dyspnoea, exercise capacity) and American Thoracic Society/European Respiratory Society/Global Initiative of Chronic Obstructive Lung Disease criteria were prospectively followed. Demographics, lung function, St George’s Respiratory Questionnaire, BODE index, the components of the BODE index and comorbidity were determined. Survival was documented and sex differences were determined using Kaplan–Meier analysis. The strength of the association of the studied variables with mortality was determined using multivariate and receiver operating curves analysis. All-cause (40 versus 18%) and respiratory mortality (24 versus 10%) were higher in males than females. Multivariate analysis identified the BODE index in females and the BODE index and Charlson comorbidity score in males as the best predictors of mortality. The area under the curve of the BODE index was a better predictor of mortality than the forced expiratory volume in one second for both sexes. At similar chronic obstructive pulmonary disease severity by BODE index and forced expiratory volume in one second, females have significantly better survival than males. For both sexes the BODE index is a better predictor of survival than the forced expiratory volume in one second

    On the concentration and size distribution of sub-micron aerosol in the Galápagos Islands

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    During the CHARLEX campaign in the Galápagos Islands, a Scanning Particle Mobility Sizer was deployed on San Cristobal Island in July-August 2011 to carry out size-resolved measurements of the concentration of submicron aerosols. To our knowledge these are the first measurements of aerosol concentrations in this unique environment. The particles with marine origin displayed a tri-modal number size distribution with peak diameters of 0.016 μm, 0.050 μm and 0.174 μm and a cloud-processed intermodal minimum at 0.093 μm. The mean total aerosol number concentration for the marine contribution was 470 ± 160 cm. A low particle concentration of 70 ± 50 cm for the nucleation size range was measured, but no evidence of new particle production in the atmospheric marine boundary layer (MBL) was observed. The concentration of the Aitken size mode was found to be related to aerosol entrainment from the free troposphere off the coast of Chile followed by transport within the MBL to the Galápagos Islands. Cloud processing may activate the particles in the Aitken size range, growing through 'in-cloud' sulphate production and increasing the particle concentration in the accumulation size range. The 0.093 μm cloud processed minima suggests that the critical supersaturation at which the particle is activated to a cloud droplet is in the 0.14-0.21% range. The daytime marine particle background concentration was influenced by human activity around the sampling site, as well as by new particle formation triggered by biogenic emissions from the vegetation cover of the island's semiarid lowlands. Effective CCN formation may play a role in the formation and properties of the stratus clouds, which permanently cover the top of the windward side of the islands and establish one of their characteristic climatic bands.Peer Reviewe

    Production of Neutron-rich Heavy Residues and the Freeze-out Temperature in the Fragmentation of Relativistic 238U Projectiles Determined by the Isospin Thermometer

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    Isotope yields of heavy residues produced in collisions of 238U with lead at 1AGeV show indications for a simultaneous break-up process. From the average N-over-Z ratio of the final residues up to Z = 70, the average limiting temperature of the break-up configuration at freeze out was determined to T approximately 5 MeV using the isospin-thermometer method. Consequences for the understanding of other phenomena in highly excited nuclear systems are discussed.Comment: 22 pages, 9 figures, accepted by Nucl. Phys.

    Dynamic Virtual Network Reconfiguration Over SDN Orchestrated Multitechnology Optical Transport Domains

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    Network virtualization is an emerging technique that enables multiple tenants to share an underlying physical infrastructure, isolating the traffic running over different virtual infrastructures/tenants. This technique aims to improve network utilization, while reducing the complexities in terms of network management for operators. Applied to this context, software defined networking (SDN) paradigm can ease network configurations by enabling network programmability and automation, which reduces the amount of operations required from both service and infrastructure providers. SDN techniques are decreasing vendor lock-in issues due to specific configuration methods or protocols. Application-based Network Operations (ABNO) is a toolbox of key network functional components with the goal of offering application-driven network management. Service provisioning using ABNO may involve direct configuration of data plane elements or delegate it to several control plane modules. We validate the applicability of ABNO to multi-tenant virtual networks in multi-technology optical domains based on two scenarios, in which multiple control plane instances are orchestrated by the architecture. Congestion Detection and Failure Recovery, are chosen to demonstrate fast recalculation and reconfiguration, while hiding the configurations in the physical layer from the upper layer.Grant numbers : supported by the Spanish Ministry of Economy and Competitiveness through the project FARO (TEC2012-38119)

    DNA methylation and histone acetylation of rat methionine adenosyltransferase 1A and 2A genes is tissue-specific

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    Methionine adenosyltransferase (MAT) catalyzes the biosynthesis of S-adenosylmethionine (AdoMet). In mammals MAT activity derives from two separate genes which display a tissue-specific pattern of expression. While MAT1A is expressed only in the adult liver, MAT2A is expressed in non-hepatic tissues. The mechanisms behind the selective expression of these two genes are not fully understood. In the present report we have evaluated MAT1A and MAT2A methylation in liver and in other tissues, such as kidney, by methylation-sensitive restriction enzyme digestion of genomic DNA. Our data indicate that MAT1A is hypomethylated in liver and hypermethylated in non-expressing tissues. The opposite situation is found for MAT2A. Additionally, histones associated to MAT1A and MAT2A genes showed enhanced levels of acetylation in expressing tissues (two-fold for MAT1A and 3.5-fold for MAT2A liver and kidney respectively). These observations support a role for chromatin structure and its modification in the tissue-specific expression of both MAT genes

    Liver-specific methionine adenosyltransferase MAT1A gene expression is associated with a specific pattern of promoter methylation and histone acetylation: implications for MAT1A silencing during transformation

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    Methionine adenosyltransferase (MAT) is the enzyme that catalyzes the synthesis of S-adenosylmethionine (AdoMet), the main donor of methyl groups in the cell. In mammals MAT is the product of two genes, MAT1A and MAT2A. MAT1A is expressed only in the mature liver whereas fetal hepatocytes, extrahepatic tissues and liver cancer cells express MAT2A. The mechanisms behind the tissue and differentiation state specific MAT1A expression are not known. In the present work we examined MAT1A promoter methylation status by means of methylation sensitive restriction enzyme analysis. Our data indicate that MAT1A promoter is hypomethylated in liver and hypermethylated in kidney and fetal rat hepatocytes, indicating that this modification is tissue specific and developmentally regulated. Immunoprecipitation of mononucleosomes from liver and kidney tissues with antibodies mainly specific to acetylated histone H4 and subsequent Southern blot analysis with a MAT1A promoter probe demonstrated that MAT1A expression is linked to elevated levels of chromatin acetylation. Early changes in MAT1A methylation are already observed in the precancerous cirrhotic livers from rats, which show reduced MAT1A expression. Human hepatoma cell lines in which MAT1A is not expressed were also hypermethylated at this locus. Finally we demonstrate that MAT1A expression is reactivated in the human hepatoma cell line HepG2 treated with 5-aza-2'-deoxycytidine or the histone deacetylase inhibitor trichostatin, suggesting a role for DNA hypermethylation and histone deacetylation in MAT1A silencing
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