When Collectivity Makes a Difference: Theoretical and Empirical Insights from Urban and Rural Communities in Colombia

[EN] In this paper, we analyse two Colombian communities using elements of the capability approach. The first, Comuna 8, is an urban community in Medellín, Colombia¿s second largest city. The second community is a Zona de Reserva Campesina (Peasant Farmer Reserve Zone) in the Cabrera municipality, in the Department of Cundinamarca. We explore the reasons why people value being part of a community, along with the collective capabilities that are expanded through community participation. As a product of these capabilities communities plan their own territories, which are examples of collective functionings. Social and environmental conversion factors, as well the historical background of the two communities, are key elements in the analysis. Finally, this research sheds light on individual and collective agency. This agency not only occurs in spaces recognised by Colombian law, but also in areas claimed by the communities themselves.This work was supported by Programa Adsideo 2015, Centro de Cooperacion al Desarrollo, Universitat Politecnica de Valencia. Ayudas Salvador de Madariaga, Subprograma de Movilidad, Plan Estatal de Investigacion Cientifica y Tecnica y de Innovacion 2013-2016.Boni Aristizábal, A.; Millan Franco, GF.; Millan Franco, MA. (2018). When Collectivity Makes a Difference: Theoretical and Empirical Insights from Urban and Rural Communities in Colombia. Journal of Human Development and Capabilities. 19(2):216-231. https://doi.org/10.1080/19452829.2017.1412408S216231192Alkire, S. (2002). Valuing Freedoms. doi:10.1093/0199245797.001.0001Biggeri, M., & Ferrannini, A. (2014). Opportunity Gap Analysis: Procedures and Methods for Applying the Capability Approach in Development Initiatives. Journal of Human Development and Capabilities, 15(1), 60-78. doi:10.1080/19452829.2013.837036Boni, A., & Walker, M. (2016). Universities and Global Human Development. doi:10.4324/9781315742793Crocker, D. A., & Robeyns, I. (s. f.). Capability and Agency. Amartya Sen, 60-90. doi:10.1017/cbo9780511800511.005Deneulin, S. (2014). Wellbeing, Justice and Development Ethics. doi:10.4324/9781315867090Deneulin, S., and S. Alkire. 2009. “A Normative Framework for Development?” InAn Introduction to the Human Development and Capability Approach: Freedom and Agency, edited by S. Deneulin and L. Shahani, 19–31. London: Earthscan.Drydyk, J. (2013). Empowerment, agency, and power. Journal of Global Ethics, 9(3), 249-262. doi:10.1080/17449626.2013.818374Apsan Frediani, A., Boni, A., & Gasper, D. (2014). Approaching Development Projects from a Human Development and Capability Perspective. Journal of Human Development and Capabilities, 15(1), 1-12. doi:10.1080/19452829.2013.879014Gaventa, J. (2006). Finding the Spaces for Change: A Power Analysis. IDS Bulletin, 37(6), 23-33. doi:10.1111/j.1759-5436.2006.tb00320.xHill, J. L. (1996). Psychological sense of community: Suggestions for future research. Journal of Community Psychology, 24(4), 431-438. doi:10.1002/(sici)1520-6629(199610)24:43.0.co;2-tIbrahim, S. S. (2006). From Individual to Collective Capabilities: The Capability Approach as a Conceptual Framework for Self‐help. Journal of Human Development, 7(3), 397-416. doi:10.1080/14649880600815982McMillan, D. W., & Chavis, D. M. (1986). Sense of community: A definition and theory. Journal of Community Psychology, 14(1), 6-23. doi:10.1002/1520-6629(198601)14:13.0.co;2-iRamos-Vidal, I., & Maya-Jariego, I. (2014). Sentido de comunidad, empoderamiento psicológico y participación ciudadana en trabajadores de organizaciones culturales. Psychosocial Intervention, 23(3), 169-176. doi:10.1016/j.psi.2014.04.00

Protective Activity of Streptococcus pneumoniae Spr1875 Protein Fragments Identified Using a Phage Displayed Genomic Library

There is considerable interest in pneumococcal protein antigens capable of inducing serotype-independent immunoprotection and of improving, thereby, existing vaccines. We report here on the immunogenic properties of a novel surface antigen encoded by ORF spr1875 in the R6 strain genome. An antigenic fragment encoded by spr1875, designated R4, was identified using a Streptococcus pneumoniae phage displayed genomic library after selection with a human convalescent serum. Immunofluorescence analysis with anti-R4 antisera showed that Spr1875 was expressed on the surface of strains belonging to different serotypes. Moreover, the gene was present with little sequence variability in 27 different pneumococcal strains isolated worldwide. A mutant lacking Spr1875 was considerably less virulent than the wild type D39 strain in an intravenous mouse model of infection. Moreover, immunization with the R4 recombinant fragment, but not with the whole Spr1875 protein, induced significant protection against sepsis in mice. Lack of protection after immunization with the whole protein was related to the presence of immunodominant, non-protective epitopes located outside of the R4 fragment. In conclusion, our data indicate that Spr1875 has a role in pneumococcal virulence and is immunogenic. As the R4 fragment conferred immunoprotection from experimental sepsis, selected antigenic fragments of Spr1875 may be useful for the development of a pneumococcal protein-based vaccine

2013 WSES guidelines for management of intra-abdominal infections

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