33 research outputs found

    Quantum Chiral Superfields

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    We define the ordinary Minkowski space inside the conformal space according to Penrose and Manin as homogeneous spaces for the Poincar\'e and conformal group respectively. We realize the supersymmetric (SUSY) generalizations of such homogeneous spaces over the complex and the real fields. We finally investigate chiral (antichiral) superfields, which are superfields on the super Grassmannian, Gr(2|1, 4|1), respectively on Gr(2|0, 4|1). They ultimately give the twistor coordinates necessary to describe the conformal superspace as the flag Fl(2|0, 2|1; 4|1) and the Minkowski superspace as its big cell.Comment: 10 pages. To appear in the proceedings of the ' Avenues of Quantum Field Theory in Curved Spacetime September 14-16, 2022. University of Genova (Italy

    Algebraic and Differential Star Products on Regular Orbits of Compact Lie Groups

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    In this paper we study a family of algebraic deformations of regular coadjoint orbits of compact semisimple Lie groups with the Kirillov Poisson bracket. The deformations are restrictions of deformations on the dual of the Lie algebra. We prove that there are non isomorphic deformations in the family. The star products are not differential, unlike the star products considered in other approaches. We make a comparison with the differential star product canonically defined by Kontsevich's map

    Supersymmetry in noncommutative superspaces

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    Non commutative superspaces can be introduced as the Moyal-Weyl quantization of a Poisson bracket for classical superfields. Different deformations are studied corresponding to constant background fields in string theory. Supersymmetric and non supersymmetric deformations can be defined, depending on the differential operators used to define the Poisson bracket. Some examples of deformed, 4 dimensional lagrangians are given. For extended superspace (N>1), some new deformations can be defined, with no analogue in the N=1 case.Comment: 23 pages, AMS-LaTeX. Misprints corrected, references adde

    Red de coordinación de actividades docentes interuniversitarias en el grado de Ciencias del Mar

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    Fruto del convenio marco de colaboración entre las Universidades de Vigo y Alicante y enmarcado dentro de las prácticas docentes interuniversitarias de la Facultad de Ciencias, se ha desarrollado una actividad de prácticas de campo para los alumnos del segundo curso del grado en Ciencias del Mar de la Universidad de Alicante. A través de esta actividad se propone la participación de los estudiantes en otro contexto universitario (Universidad de Vigo), interactuando con profesorado y estudiantes de otra universidad. Los objetivos incluyen actividades de adquisición de conocimientos complementarios (comparación entre ambientes atlánticos y mediterráneos, biodiversidad litoral costera y marina, geomorfología y sedimentología costera marina) y aptitudes para la capacitación de técnicas de muestreo en medios litorales y en dragados mediante embarcación

    Assessing the impact of COVID-19 on liver cancer management (CERO-19).

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    BACKGROUND & AIMS: The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges to healthcare systems and it may have heavily impacted patients with liver cancer (LC). Herein, we evaluated whether the schedule of LC screening or procedures has been interrupted or delayed because of the COVID-19 pandemic. METHODS: An international survey evaluated the impact of the COVID-19 pandemic on clinical practice and clinical trials from March 2020 to June 2020, as the first phase of a multicentre, international, and observational project. The focus was on patients with hepatocellular carcinoma or intrahepatic cholangiocarcinoma, cared for around the world during the first COVID-19 pandemic wave. RESULTS: Ninety-one centres expressed interest to participate and 76 were included in the analysis, from Europe, South America, North America, Asia, and Africa (73.7%, 17.1%, 5.3%, 2.6%, and 1.3% per continent, respectively). Eighty-seven percent of the centres modified their clinical practice: 40.8% the diagnostic procedures, 80.9% the screening programme, 50% cancelled curative and/or palliative treatments for LC, and 41.7% modified the liver transplantation programme. Forty-five out of 69 (65.2%) centres in which clinical trials were running modified their treatments in that setting, but 58.1% were able to recruit new patients. The phone call service was modified in 51.4% of centres which had this service before the COVID-19 pandemic (n = 19/37). CONCLUSIONS: The first wave of the COVID-19 pandemic had a tremendous impact on the routine care of patients with liver cancer. Modifications in screening, diagnostic, and treatment algorithms may have significantly impaired the outcome of patients. Ongoing data collection and future analyses will report the benefits and disadvantages of the strategies implemented, aiding future decision-making. LAY SUMMARY: The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges to healthcare systems globally. Herein, we assessed the impact of the first wave pandemic on patients with liver cancer and found that routine care for these patients has been majorly disrupted, which could have a significant impact on outcomes

    Genomic Ancestry, CYP2D6, CYP2C9, and CYP2C19 Among Latin Americans

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    We present the distribution of CYP2D6, CYP2C9, and CYP2C19 variants and predicted phenotypes in 33 native and admixed populations from Ibero-America (n > 6,000) in the context of genetic ancestry (n = 3,387). Continental ancestries are the major determinants of frequencies of the increased-activity allele CYP2C19*17 and CYP2C19 gUMs (negatively associated with Native American ancestry), decreased-activity alleles CYP2D6*41 and CYP2C9*2 (positively associated with European ancestry), and decreased-activity alleles CYP2D6*17 and CYP2D6*29 (positively associated with African ancestry). For the rare alleles, CYP2C9*2 and CYPC19*17, European admixture accounts for their presence in Native American populations, but rare alleles CYP2D6*5 (null-activity), CYP2D6-multiplication alleles (increased activity), and CYP2C9*3 (decreased-activity) were present in the pre-Columbian Americas. The study of a broad spectrum of Native American populations from different ethno-linguistic groups show how autochthonous diversity shaped the distribution of pharmaco-alleles and give insights on the prevalence of clinically relevant phenotypes associated with drugs, such as paroxetine, tamoxifen, warfarin, and clopidogrel

    Surviving in isolation: genetic variation, bottlenecks and reproductive strategies in the Canarian endemic Limonium macrophyllum (Plumbaginaceae)

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    Oceanic archipelagos are typically rich in endemic taxa, because they offer ideal conditions for diversification and speciation in isolation. One of the most remarkable evolutionary radiations on the Canary Islands comprises the 16 species included in Limonium subsection Nobiles, all of which are subject to diverse threats, and legally protected. Since many of them are single-island endemics limited to one or a few populations, there exists a risk that a loss of genetic variation might limit their longterm survival. In this study, we used eight newly developed microsatellite markers to characterize the levels of genetic variation and inbreeding in L. macrophyllum, a species endemic to the North-east of Tenerife that belongs to Limonium subsection Nobiles. We detected generally low levels of genetic variation over all populations (HT = 0.363), and substantial differentiation among populations (FST = 0.188;RST = 0.186) coupled with a negligible degree of inbreeding (F = 0.042). Obligate outcrossing may have maintained L. macrophyllum relatively unaffected by inbreeding despite the species’ limited dispersal ability and the genetic bottlenecks likely caused by a prolonged history of grazing. Although several factors still constitute a risk for the conservation of L. macrophyllum, the lack of inbreeding and the recent positive demographic trends observed in the populations of this species are factors that favour its future persistence

    Seguimiento de variables ecofisiológicas en plantones de "Pinus halepensis" Miller, en un ciclo de secado: ¿puede encontrarse diferente comportamiento en plantones producidos con diferentes substratos?

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    Se han producido plantones de Pinus halepensis Miller utilizando dos tipos de substrato: uno a base de lodos de depuradora compostados con orujo de uva y otro usando turba convencional. En 240 de estos individuos, de 14 meses de edad, se realizó el seguimiento de variables ecofisiológicas durante un ciclo de secado, después de caracterizar estructuralmente ambas muestras. Los plantones producidos con lodos, respecto a los producidos con turba, presentan mayores valores (significativos estadísticamente) de altura, diámetro basal, biomasa de raíz y biomasa aérea. Pese a que la turba puede retener hasta 6,5 gramos de agua por gramo de substrato y el lodo tan solo 1,2 gramos, no se han encontrado diferencias significativas en el potencial hídrico de los individuos con distinto substrato de plantación, lo que indica una mejor adaptación de estos individuos a la sequía. En cuanto a la fotosíntesis (A) no se han encontrado diferencias, sin embargo la transpiración (E) y conductancia estomática (gs) son menores en los individuos producidos con lodo, lo que indica el mejor control que ejercen los mismos sobre el cierre de los estomas
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